Effect of CPAP therapy on cardiovascular events and mortality in patients with obstructive sleep apnea: a meta-analysis

Sleep and Breathing

Volumn 20, Issue 3, 2016, Pages 965-974

  Guo, Jun ^a   Sun, Yu ^b,c   Xue, Li Jun ^d   Huang, Zi Yang ^c   Wang, Yong Shen ^b   Zhang, Lei ^b   Zhou, Gui Hua ^b   Yuan, Li Xin ^b  

^a TSINGHUA UNIVERSITY   (China)

^b Tuberculosis Hospital of Binzhou City   (China)

^c FUJIAN MEDICAL UNIVERSITY   (China)

^d Bao an people s hospital   (China)

Author keywords

Cardiovascular events; Continuous positive airway pressure; Meta analysis; Mortality; Obstructive sleep apnea; Sleepiness

Indexed keywords

ARTICLE; BODY MASS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; DIABETES MELLITUS; DIASTOLIC BLOOD PRESSURE; EPWORTH SLEEPINESS SCALE; FOLLOW UP; HUMAN; INCIDENCE; META ANALYSIS; OXYGEN THERAPY; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; QUALITY CONTROL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SLEEP DISORDERED BREATHING; SMOKING; SYSTEMATIC REVIEW; SYSTOLIC BLOOD PRESSURE; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; CAUSE OF DEATH; COMORBIDITY; COMPLICATION; MORTALITY; RISK; SLEEP APNEA, OBSTRUCTIVE;

BLOOD PRESSURE; BODY MASS INDEX; CARDIOVASCULAR DISEASES; CAUSE OF DEATH; COMORBIDITY; CONTINUOUS POSITIVE AIRWAY PRESSURE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RISK; SLEEP APNEA, OBSTRUCTIVE;

EID: 84957951118     PISSN: 15209512     EISSN: 15221709     Source Type: Journal    
DOI: 10.1007/s11325-016-1319-y     Document Type: Article

References (33)

1. Pan L, Xie X, Liu D, Ren D, Guo Y (2016) Obstructive sleep apnoea and risks of allcause mortality: preliminary evidence from prospective cohort studies. Sleep Breath. doi:10.1007/s11325-015-1295-7
2. Hu X, Fan J, Chen S, Yin Y, Zrenner B (2015) The role of continuous airway pressure in blood pressure control for patients with obstructive sleep apnea and hypertension: a meta-analysis of randomized controlled trials. J Clin Hypertens (Greenwich) 17(3):215–222
3. Barbe F, Duran-Cantolla J, Capote F, de la Pena M, Chiner E, Masa JF, Gonzalez M, Marín JM, Garcia-Rio F, de Atauri JD, Terán J, Mayos M, Monasterio C, del Campo F, Gomez S, de la Torre MS, Martinez M, Montserrat JM, Spanish Sleep and Breathing Group (2010) Long-term effect of continuous positive airway pressure in hypertensive patients with sleep apnea. Am J Respir Crit Care Med 181(7):718–726
4. Gottlieb DJ, Punjabi NM, Mehra R, Patel SR, Quan SF, Babineau DC, Tracy RP, Rueschman M, Blumenthal RS, Lewis EF, Bhatt DL, Redline S (2014) CPAP versus oxygen in obstructive sleep apnea. N Engl J Med 370(24):2276–2285
5. Xie X, Pan L, Ren D, Du C, Guo Y (2013) Effects of continuous positive airway pressure therapy on systemic inflammation in obstructive sleep apnea: a meta-analysis. Sleep Med 14(11):1139–1150
6. Jullian-Desayes J-FM, Tamisier R, Launois S, Borel AL, Levy P, Pepin JL (2015) Impact of obstructive sleep apnea treatment by continuous positive airway pressure on cardiometabolic biomarkers: a systematic review from sham CPAP randomized controlled trials. Sleep Med Rev 21:23–38
7. Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group (2009) Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. J Clin Epidemiol 62(10):1006–1012
8. DerSimonian R, Laird N (1986) Meta-analysis in clinical trials. Control Clin Trials 7(3):177–188
9. Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327(7414):557–560
10. Robinson GV, Smith DM, Langford BA, Davies RJ, Stradling JR (2006) Continuous positive airway pressure does not reduce blood pressure in nonsleepy hypertensive OSA patients. Eur Respir J 27(6):1229–1235
11. Lozano L, Tovar JL, Sampol G, Romero O, Jurado MJ, Segarra A, Espinel E, Ríos J, Untoria MD, Lloberes P (2010) Continuous positive airway pressure treatment in sleep apnea patients with resistant hypertension: a randomized, controlled trial. J Hypertens 28(10):2161–2168
12. Durán-Cantolla J, Aizpuru F, Montserrat JM, Ballester E, Terán-Santos J, Aguirregomoscorta JI, Gonzalez M, Lloberes P, Masa JF, De La Peña M, Carrizo S, Mayos M, Barbé F, Spanish Sleep and Breathing Group (2010) Continuous positive airway pressure as treatment for systemic hypertension in people with obstructive sleep apnoea: randomised controlled trial. BMJ 341:c5991
13. Phillips CL, Yee BJ, Marshall NS, Liu PY, Sullivan DR, Grunstein RR (2011) Continuous positive airway pressure reduces postprandial lipidemia in obstructive sleep apnea: a randomized, placebo-controlled crossover trial. Am J Respir Crit Care Med 184(3):355–361
14. Drager LF, Pedrosa RP, Diniz PM, Diegues-Silva L, Marcondes B, Couto RB, Giorgi DM, Krieger EM, Lorenzi-Filho G (2011) The effects of continuous positive airway pressure on prehypertension and masked hypertension in men with severe obstructive sleep apnea. Hypertension 57(3):549–555
15. Barbé F, Durán-Cantolla J, Sánchez-de-la-Torre M, Martínez-Alonso M, Carmona C, Barceló A, Chiner E, Masa JF, Gonzalez M, Marín JM, Garcia-Rio F, Diaz de Atauri J, Terán J, Mayos M, de la Peña M, Monasterio C, de Campo F, JM M, Spanish Sleep And Breathing Network (2012) Effect of continuous positive airway pressure on the incidence of hypertension and cardiovascular events in nonsleepy patients with obstructive sleep apnea: a randomized controlled trial. JAMA 307(20):2161–2168
16. Kushida CA, Nichols DA, Holmes TH, Quan SF, Walsh JK, Gottlieb DJ, Simon RD Jr, Guilleminault C, White DP, Goodwin JL, Schweitzer PK, Leary EB, Hyde PR, Hirshkowitz M, Green S, McEvoy LK, Chan C, Gevins A, Kay GG, Bloch DA, Crabtree T, Dement WC (2012) Effects of continuous positive airway pressure on neurocognitive function in obstructive sleep apnea patients: The Apnea Positive Pressure Long-term Efficacy Study (APPLES). Sleep 35(12):1593–1602
17. Martínez-García MA, Capote F, Campos-Rodríguez F, Lloberes P, Díaz de Atauri MJ, Somoza M, Masa JF, González M, Sacristán L, Barbé F, Durán-Cantolla J, Aizpuru F, Mañas E, Barreiro B, Mosteiro M, Cebrián JJ, dela Peña M, García-Río F, Maimó A, Zapater J, Hernández C, Grau SanMarti N, Montserrat JM, Spanish Sleep Network (2013) Effect of CPAP on blood pressure in patients with obstructive sleep apnea and resistant hypertension: the HIPARCO randomized clinical trial. JAMA 310(22):2407–2415
18. Pedrosa RP, Drager LF, de Paula LK, Amaro AC, Bortolotto LA, Lorenzi-Filho G (2014) Effects of OSA treatment on BP in patients with resistant hypertension: a randomized trial. Chest 144(5):1487–1494
19. Lloberes P, Sampol G, Espinel E, Segarra A, Ramon MA, Romero O, Ferrer R, Martínez-Garcia MA, Tovar JL (2014) A randomized controlled study of CPAP effect on plasma aldosterone concentration in patients with resistant hypertension and obstructive sleep apnea. J Hypertens 32(8):1650–1657
20. McMillan A, Bratton DJ, Faria R, Laskawiec-Szkonter M, Griffin S, Davies RJ, Nunn AJ, Stradling JR, Riha RL, Morrell MJ, Investigators PREDICT (2014) Continuous positive airway pressure in older people with obstructive sleep apnoea syndrome (PREDICT): a 12-month, multicentre, randomised trial. Lancet Respir Med 2(10):804–812
21. Chirinos JA, Gurubhagavatula I, Teff K, Rader DJ, Wadden TA, Townsend R, Foster GD, Maislin G, Saif H, Broderick P, Chittams J, Hanlon AL, Pack AI (2014) CPAP, weight loss, or both for obstructive sleep apnea. N Engl J Med 370(24):2265–2275
22. Muxfeldt ES, Margallo V, Costa LM, Guimarães G, Cavalcante AH, Azevedo JC, de Souza F, Cardoso CR, Salles GF (2015) Effects of continuous positive airway pressure treatment on clinic and ambulatory blood pressures in patients with obstructive sleep apnea and resistant hypertension: a randomized controlled trial. Hypertension 65(4):736–742
23. Huang Z, Liu Z, Luo Q, Zhao Q, Zhao Z, Ma X, Liu W, Yang D (2015) Long-term effects of continuous positive airway pressure on blood pressure and prognosis in hypertensive patients with coronary heart disease and obstructive sleep apnea: a randomized controlled trial. Am J Hypertens 28(3):300–306
24. Hoyos CM, Yee BJ, Wong KK, Grunstein RR, Phillips CL (2015) Treatment of Sleep Apnea With CPAP Lowers Central and Peripheral Blood Pressure Independent of the Time-of-Day: A Randomized Controlled Study. Am J Hypertens pii: hpv023. [Epub ahead of print]
25. Parra O, Sanchez-Armengol A, Capote F, Bonnin M, Arboix A, Campos- Rodriguez F, Pérez-Ronchel J, Durán-Cantolla J, Martínez-Null C, de la Peña M, Jiménez MC, Masa F, Casadon I, Alonso ML, Macarrón JL (2015) Efficacy of continuous positive airway pressure treatment on 5-year survival in patients with ischaemic stroke and obstructive sleep apnea: a randomized controlled trial. J Sleep Res 24(1):47–53
26. Kendzerska T, Gershon AS, Hawker G, Leung RS, Tomlinson G (2014) Obstructive sleep apnea and risk of cardiovascular events and all-cause mortality: a decade-long historical cohort study. PLoS Med 11:e1001599
27. Peppard PE, Young T, Palta M, Dempsey J, Skatrud J (2000) Longitudinal study of moderate weight change and sleep-disordered breathing. JAMA 284(23):3015–3021
28. Feng Y, Zhang Z, Dong ZZ (2015) Effects of continuous positive airway pressure therapy on glycaemic control, insulin sensitivity and body mass index in patients with obstructive sleep apnoea and type 2 diabetes: a systematic review and meta-analysis. NPJ Prim Care Respir Med 25:15005
29. Drager LF, Brunoni AR, Jenner R, Lorenzi-Filho G, Benseñor IM, Lotufo PA (2015) Effects of CPAP on body weight in patients with obstructive sleep apnoea: a meta-analysis of randomised trials. Thorax 70(3):258–264
30. Fava C, Dorigoni S, Dalle Vedove F, Danese E, Montagnana M, Guidi GC, Narkiewicz K, Minuz P (2014) Effect of CPAP on blood pressure in patients with OSA/hypopnea a systematic review and meta-analysis. Chest 145(4):762–771
31. Rodway GW, Weaver TE, Mancini C, Cater J, Maislin G, Staley B, Ferguson KA, George CF, Schulman DA, Greenberg H, Rapoport DM, Walsleben JA, Lee-Chiong T, Kuna ST (2010) Evaluation of sham-CPAP as a placebo in CPAP intervention studies. Sleep 33(2):260–266
32. Hui DS, To KW, Ko FW, Fok JP, Chan MC, Ngai JC, Tung AH, Ho CW, Tong MW, Szeto CC, Yu CM (2006) Nasal CPAP reduces systemic blood pressure in patients with obstructive sleep apnoea and mild sleepiness. Thorax 61(12):1083–1090
33. Krieger J, Kurtz D, Petiau C, Sforza E, Trautmann D (1996) Long-term compliance with CPAP therapy in obstructive sleep apnea patients and in snorers. Sleep 19(9 Suppl):S136–S143