White matter hyperintensity burden in elderly cohort studies: The Sunnybrook Dementia Study, Alzheimer's Disease Neuroimaging Initiative, and Three-City Study

Alzheimer's and Dementia

Volumn 12, Issue 2, 2016, Pages 203-210

  Ramirez, Joel ^a,b   McNeely, Alicia A ^a,b   Scott, Christopher J M ^a,b   Masellis, Mario ^a,b,c,d,e   Black, Sandra E ^a,b,c,e  

^a Canada   (Canada)

^b HEART AND STROKE FOUNDATION OF CANADA   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d CENTRE FOR ADDICTION AND MENTAL HEALTH   (Canada)

^e SUNNYBROOK RESEARCH INSTITUTE   (Canada)

Author keywords

Aging; Alzheimer's disease; Cerebrovascular disease; Dementia; Elderly cohort; Population studies; White matter hyperintensities

Indexed keywords

ADULT; AGED; AGING; ALZHEIMER DISEASE; CEREBROVASCULAR DISEASE; CLINICAL RESEARCH; COHORT ANALYSIS; HUMAN; MINI MENTAL STATE EXAMINATION; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; REVIEW; VERY ELDERLY; WHITE MATTER; WHITE MATTER HYPERINTENSITY; BRAIN; CANADA; COMPARATIVE STUDY; FEMALE; FRANCE; MALE; MIDDLE AGED; MILD COGNITIVE IMPAIRMENT; MYELINATED NERVE; PATHOLOGY; PATHOPHYSIOLOGY; UNITED STATES;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BRAIN; CANADA; CEREBROVASCULAR DISORDERS; COHORT STUDIES; FEMALE; FRANCE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MILD COGNITIVE IMPAIRMENT; NERVE FIBERS, MYELINATED; NEUROIMAGING; UNITED STATES; WHITE MATTER;

EID: 84957843473     PISSN: 15525260     EISSN: 15525279     Source Type: Journal    
DOI: 10.1016/j.jalz.2015.06.1886     Document Type: Article

References (58)

1. Alzheimer's Disease International. World Alzheimer Report 2014: Dementia and risk reduction: An analysis of protective and modifiable factors. London, UK: 2014.
2. L. Fratiglioni, L.J. Launer, K. Andersen, M.M. Breteler, J.R. Copeland, J.F. Dartigues, and et al. Incidence of dementia and major subtypes in Europe: A collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group Neurology 54 2000 S10 S15
3. S. Black, and C. Iadecola Vascular cognitive impairment: Small vessels, big toll: Introduction Stroke 40 2009 S38 S39
4. D.S. Knopman Cerebrovascular pathology in cognitive impairment: New (in)sights Neurology 78 2012 1032 1033
5. J.C. De la Torre Detection, prevention, and pre-clinical treatment of Alzheimer's disease J Alzheimers Dis 2014 64 65
6. F. Portet, A.M. Brickman, Y. Stern, N. Scarmeas, J. Muraskin, F.A. Provenzano, and et al. Metabolic syndrome and localization of white matter hyperintensities in the elderly population Alzheimers Dement 8 2012 S88 S95.e1
7. J.M. Wardlaw, E.E. Smith, G.J. Biessels, C. Cordonnier, F. Fazekas, R. Frayne, and et al. Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration Lancet Neurol 12 2013 822 838
8. J.A. Schneider, Z. Arvanitakis, W. Bang, and D.A. Bennett Mixed brain pathologies account for most dementia cases in community-dwelling older persons Neurology 69 2007 2197 2204
9. A. Viswanathan, W.A. Rocca, and C. Tzourio Vascular risk factors and dementia: How to move forward? Neurology 72 2009 368 374
10. M.M. Mielke, T. Montine, and A.S. Khachaturian Vascular diseases: one pathway toward new conceptual models of dementia Alzheimers Dement 8 2012 S69 70
11. V. Deramecourt, J.Y. Slade, A.E. Oakley, R.H. Perry, P.G. Ince, C.A. Maurage, and et al. Staging and natural history of cerebrovascular pathology in dementia Neurology 78 2012 1043 1050
12. J.B. Toledo, S.E. Arnold, K. Raible, J. Brettschneider, S.X. Xie, M. Grossman, and et al. Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer's Coordinating Centre Brain 136 2013 2697 2706
13. A. Moghekar, M. Kraut, W. Elkins, J. Troncoso, A.B. Zonderman, S.M. Resnick, and et al. Cerebral white matter disease is associated with Alzheimer pathology in a prospective cohort Alzheimers Dement 8 2012 S71 S77
14. L. Pantoni Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges Lancet Neurol 9 2010 689 701
15. A.A. Gouw, A. Seewann, W.M. van der Flier, F. Barkhof, A.M. Rozemuller, P. Scheltens, and et al. Heterogeneity of small vessel disease: A systematic review of MRI and histopathology correlations J Neurol Neurosurg Psychiatry 82 2011 126 135
16. M. O'Sullivan Leukoaraiosis Pract Neurol 8 2008 26 38
17. S.E. Black, F.Q. Gao, and J. Bilbao Understanding white matter disease: Imaging-pathological correlations in vascular cognitive impairment Stroke 40 2009 S48 52
18. D.M. Moody, W.R. Brown, V.R. Challa, and R.L. Anderson Periventricular venous collagenosis: Association with leukoaraiosis Radiology 194 1995 469 476
19. M. Haglund, and E. Englund Cerebral amyloid angiopathy, white matter lesions and Alzheimer encephalopathy - a histopathological assessment Dement Geriatr Cogn Disord 14 2002 161 166
20. A. Viswanathan, and H. Chabriat Cerebral microhemorrhage Stroke 37 2006 550 555
21. E.E. Smith, and F. Eichler Cerebral amyloid angiopathy and lobar intracerebral hemorrhage Arch Neurol 63 2006 148 151
22. M. Yoshita, E. Fletcher, D. Harvey, M. Ortega, O. Martinez, D.M. Mungas, and et al. Extent and distribution of white matter hyperintensities in normal aging, MCI, and AD Neurology 67 2006 2192 2198
23. C. DeCarli, B.L. Miller, G.E. Swan, T. Reed, P.A. Wolf, and D. Carmelli Cerebrovascular and brain morphologic correlates of mild cognitive impairment in the National Heart, Lung, and Blood Institute Twin Study Arch Neurol 58 2001 643 647
24. J. Ramirez, A.A. McNeely, C.J. Scott, D.T. Stuss, and S.E. Black Subcortical hyperintensity volumetrics in Alzheimer's disease and normal elderly in the Sunnybrook Dementia Study: Correlations with atrophy, executive function, mental processing speed, and verbal memory Alzheimers Res Ther 6 2014 49
25. The Sunnybrook Dementia Study n.d. Available at: www.brainlab.ca/sunnybrookdementiastudy. Accessed March 19, 2015.
26. Alzheimer's Disease Neuroimaging Initiative n.d. Available at: www.adni.loni.usc.edu. Accessed March 19, 2015.
27. The Three-City Study n.d. Available at: www.three-city-study.com. Accessed March 19, 2015.
28. O. Godin, C. Tzourio, O. Rouaud, Y. Zhu, P. Maillard, F. Pasquier, and et al. Joint effect of white matter lesions and hippocampal volumes on severity of cognitive decline: The 3C-Dijon MRI study J Alzheimers Dis 20 2010 453 463
29. K.B. Boone, B.L. Miller, I.M. Lesser, C.M. Mehringer, E. Hill-Gutierrez, M.A. Goldberg, and et al. Neuropsychological correlates of white-matter lesions in healthy elderly subjects. A threshold effect Arch Neurol 49 1992 549 554
30. M. Albert, J. Massaro, C. Decarli, A. Beiser, S. Seshadri, P.A. Wolf, and et al. Profiles by sex of brain MRI and cognitive function in the Framingham Offspring Study Alzheimer Dis Assoc Disord 24 2010 190 193
31. C. Decarli, D.G. Murphy, M. Tranh, C.L. Grady, J.V. Haxby, J.A. Gillette, and et al. The effect of white matter hyperintensity volume on brain structure, cognitive performance, and cerebral metabolism of glucose in 51 healthy adults Neurology 45 1995 2077 2084
32. O. Carmichael, C. Schwarz, D. Drucker, E. Fletcher, D. Harvey, L. Beckett, and et al. Longitudinal changes in white matter disease and cognition in the first year of the Alzheimer disease neuroimaging initiative Arch Neurol 67 2010 1370 1378
33. J. Barnes, O.T. Carmichael, K.K. Leung, C. Schwarz, G.R. Ridgway, J.W. Bartlett, and et al. Vascular and Alzheimer's disease markers independently predict brain atrophy rate in Alzheimer's Disease Neuroimaging Initiative controls Neurobiol Aging 34 2013 1996 2002
34. A.A. McNeely, J. Ramirez, S.M. Nestor, J. Zhao, F. Gao, A. Kiss, and et al. Cholinergic subcortical hyperintensities in Alzheimer's disease patients from the Sunnybrook Dementia Study: Relationships with cognitive dysfunction and hippocampal atrophy J Alzheimers Dis 43 2015 785 796
35. O. Godin, C. Tzourio, P. Maillard, B. Mazoyer, and C. Dufouil Antihypertensive treatment and change in blood pressure are associated with the progression of white matter lesion volumes: The Three-City (3C)-Dijon Magnetic Resonance Imaging Study Circulation 123 2011 266 273
36. C.L. Satizabal, Y.C. Zhu, B. Mazoyer, C. Dufouil, and C. Tzourio Circulating IL-6 and CRP are associated with MRI findings in the elderly: The 3C-Dijon Study Neurology 78 2012 720 727
37. L. Pantoni, A.M. Basile, G. Pracucci, K. Asplund, J. Bogousslavsky, H. Chabriat, and et al. Impact of age-related cerebral white matter changes on the transition to disability - the LADIS study: Rationale, design and methodology Neuroepidemiology 24 2005 51 62
38. R. Schmidt, S. Ropele, J. Ferro, S. Madureira, A. Verdelho, K. Petrovic, and et al. Diffusion-weighted imaging and cognition in the leukoaraiosis and disability in the elderly study Stroke 41 2010 e402 e408
39. V.J. Verlinden, J.N. van der Geest, M. de Groot, A. Hofman, W.J. Niessen, A. van der Lugt, and et al. Structural and microstructural brain changes predict impairment in daily functioning Am J Med 127 2014 1089 1096.e2
40. X. Chen, W. Wen, K.J. Anstey, and P.S. Sachdev Prevalence, incidence, and risk factors of lacunar infarcts in a community sample Neurology 73 2009 266 272
41. Y. Noh, Y. Lee, S.W. Seo, J.H. Jeong, S.H. Choi, J.H. Back, and et al. A new classification system for ischemia using a combination of deep and periventricular white matter hyperintensities J Stroke Cerebrovasc Dis 23 2014 636 642
42. G. McKhann, D. Drachman, M. Folstein, R. Katzman, D. Price, and E.M. Stadlan Clinical diagnosis of Alzheimer's disease: Report of the NINCDS- ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease Neurology 34 1984 939 944
43. V.C. Hachinski, L.D. Iliff, E. Zilhka, G.H. DuBoulay, V.L. McAllister, J. Marshall, and et al. Cerebral blood flow in dementia Arch Neurol 32 1975 632 637
44. G.M. McKhann, D.S. Knopman, H. Chertkow, B.T. Hyman, C.R. Jack Jr., C.H. Kawas, and et al. The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease Alzheimers Dement 7 2011 263 269
45. P. Sachdev, R. Kalaria, J. O'Brien, I. Skoog, S. Alladi, S.E. Black, and et al. Diagnostic criteria for vascular cognitive disorders: A VASCOG statement Alzheimer Dis Assoc Disord 28 2014 206 218
46. M.A. Kling, J.Q. Trojanowski, D.A. Wolk, V.M.Y. Lee, and S.E. Arnold Vascular disease and dementias: Paradigm shifts to drive research in new directions Alzheimers Dement 9 2013 76 92
47. O. Carmichael, D. Mungas, L. Beckett, D. Harvey, S. Tomaszewski Farias, B. Reed, and et al. MRI predictors of cognitive change in a diverse and carefully characterized elderly population Neurobiol Aging 33 2012 83 95
48. E.B. Larson, and K.M. Langa Aging and incidence of dementia: A critical question Neurology 78 2012 1452 1453
49. K.M. Langa, E.B. Larson, J.H. Karlawish, D.M. Cutler, M.U. Kabeto, S.Y. Kim, and et al. Trends in the prevalence and mortality of cognitive impairment in the United States: Is there evidence of a compression of cognitive morbidity? Alzheimers Dement 4 2008 134 144
50. K.C. Manton, X.L. Gu, and S.V. Ukraintseva Declining prevalence of dementia in the U.S. elderly population Adv Gerontol 16 2005 30 37
51. W.A. Rocca, R.C. Petersen, D.S. Knopman, L.E. Hebert, D.A. Evans, K.S. Hall, and et al. Trends in the incidence and prevalence of Alzheimer's disease, dementia, and cognitive impairment in the United States Alzheimers Dement 7 2011 80 93
52. F.E. Matthews, A. Arthur, L.E. Barnes, J. Bond, C. Jagger, L. Robinson, and et al. A two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: Results of the Cognitive Function and Ageing Study I and II Lancet 382 2013 1405 1412
53. E.M.C. Schrijvers, B.F.J. Verhaaren, P.J. Koudstaal, A. Hofman, M.A. Ikram, and M.M.B. Breteler Is dementia incidence declining? Trends in dementia incidence since 1990 in the Rotterdam Study Neurology 78 2012 1456 1463
54. Medical Imaging Trial Network of Canada n.d. Available at: www.mitnec.org. Accessed March 19, 2015.
55. J.C. Tardif, J.D. Spence, T.M. Heinonen, A. Moody, J. Pressacco, R. Frayne, and et al. Atherosclerosis Imaging and the Canadian Atherosclerosis Imaging Network Can J Cardiol 29 2013 297 303
56. Canadian Atherosclerosis Imaging Network n.d. Available at: www.canadianimagingnetwork.org. Accessed March 19, 2015.
57. Ontario Neurodegenerative Disease Research Initiative n.d. Available at: www.ondri.ca. Accessed March 19, 2015.
58. J. Ramirez, E. Gibson, A. Quddus, N.J. Lobaugh, A. Feinstein, B. Levine, and et al. Lesion Explorer: A comprehensive segmentation and parcellation package to obtain regional volumetrics for subcortical hyperintensities and intracranial tissue Neuroimage 54 2011 963 973