Curcumin Nanoformulation for Cervical Cancer Treatment

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Zaman, Mohd S ^a   Chauhan, Neeraj ^a   Yallapu, Murali M ^a   Gara, Rishi K ^a   Maher, Diane M ^b   Kumari, Sonam ^a   Sikander, Mohammed ^a   Khan, Sheema ^a   Zafar, Nadeem ^a   Jaggi, Meena ^a   Chauhan, Subhash C ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b SANFORD RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CURCUMIN; LACTIC ACID; MICRORNA; MIRN21 MICRORNA, HUMAN; NANOPARTICLE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANIMAL; CELL CYCLE; CELL PROLIFERATION; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MOUSE; TUMOR CELL LINE; UTERINE CERVICAL NEOPLASMS;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CURCUMIN; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LACTIC ACID; MICE; MICRORNAS; NANOPARTICLES; POLYGLYCOLIC ACID; UTERINE CERVICAL NEOPLASMS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84957818730     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep20051     Document Type: Article

References (60)

1. Clarke, M. A. et al. Human papillomavirus DNA methylation as a potential biomarker for cervical cancer. Cancer Epidemiol Biomarkers Prev 21, 2125-2137 (2012).
2. Moore, E. E., Wark, J. D., Hopper, J. L., Erbas, B. & Garland, S. M. The roles of genetic and environmental factors on risk of cervical cancer: a review of classical twin studies. Twin Res Hum Genet 15, 79-86 (2012).
3. Zhen, S., Hu, C. M. & Bian, L. H. Glutathione S-transferase polymorphism interactions with smoking status and HPV infection in cervical cancer risk: an evidence-based meta-analysis. PLoS One 8, e83497 (2013).
4. Au, W. W., Abdou-Salama, S., Sierra-Torres, C. H. & Al-Hendy, A. Environmental risk factors for prevention and molecular intervention of cervical cancer. Int J Hyg Environ Health 210, 671-678 (2007).
5. Maher, D. M. et al. Curcumin suppresses human papillomavirus oncoproteins, restores p53, Rb, and PTPN13 proteins and inhibits benzo[a]pyrene-induced upregulation of HPV E7. Mol Carcinog 50, 47-57 (2011).
6. Alam, S., Conway, M. J., Chen, H. S. & Meyers, C. The cigarette smoke carcinogen benzo[a]pyrene enhances human papillomavirus synthesis. J Virol 82, 1053-1058 (2008).
7. Rahman, I., Biswas, S. K. & Kirkham, P. A. Regulation of inflammation and redox signaling by dietary polyphenols. Biochem Pharmacol 72, 1439-1452 (2006).
8. Tirkey, N., Kaur, G., Vij, G., Curcumin & Chopra, K. A diferuloylmethane, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rat kidneys. BMC Pharmacol 5, 15 (2005).
9. Deeb, D. D. et al. Chemosensitization of hormone-refractory prostate cancer cells by curcumin to TRAIL-induced apoptosis. J Exp Ther Oncol 5, 81-91 (2005).
10. Nardo, L., Andreoni, A., Bondani, M., Masson, M. & Hjorth Tonnesen, H. Studies on curcumin and curcuminoids. XXXIV. Photophysical properties of a symmetrical, non-substituted curcumin analogue. J Photochem Photobiol B 97, 77-86 (2009).
11. Prusty, B. K. & Das, B. C. Constitutive activation of transcription factor AP-1 in cervical cancer and suppression of human papillomavirus (HPV) transcription and AP-1 activity in HeLa cells by curcumin. Int J Cancer 113, 951-960 (2005).
12. Di Domenico, F., Foppoli, C., Coccia, R. & Perluigi, M. Antioxidants in cervical cancer: chemopreventive and chemotherapeutic effects of polyphenols. Biochim Biophys Acta 1822, 737-747 (2012).
13. Singh, M. & Singh, N. Molecular mechanism of curcumin induced cytotoxicity in human cervical carcinoma cells. Mol Cell Biochem 325, 107-119 (2009).
14. Singh, M. & Singh, N. Curcumin counteracts the proliferative effect of estradiol and induces apoptosis in cervical cancer cells. Mol Cell Biochem 347, 1-11 (2011).
15. Madden, K. et al. Proteomics-based approach to elucidate the mechanism of antitumor effect of curcumin in cervical cancer. Prostaglandins Leukot Essent Fatty Acids 80, 9-18 (2009).
16. Cheng, A. L. et al. Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Res 21, 2895-2900 (2001).
17. Anand, P., Kunnumakkara, A. B., Newman, R. A. & Aggarwal, B. B. Bioavailability of curcumin: problems and promises. Mol Pharm 4, 807-818 (2007).
18. Shehzad, A., Wahid, F. & Lee, Y. S. Curcumin in cancer chemoprevention: molecular targets, pharmacokinetics, bioavailability, and clinical trials. Arch Pharm (Weinheim) 343, 489-499 (2010).
19. Shehzad, A., Khan, S., Shehzad, O. & Lee, Y. S. Curcumin therapeutic promises and bioavailability in colorectal cancer. Drugs Today (Barc) 46, 523-532 (2010).
20. Ireson, C. et al. Characterization of metabolites of the chemopreventive agent curcumin in human and rat hepatocytes and in the rat in vivo, and evaluation of their ability to inhibit phorbol ester-induced prostaglandin E2 production. Cancer Res 61, 1058-1064 (2001).
21. Shaikh, J., Ankola, D. D., Beniwal, V., Singh, D. & Kumar, M. N. Nanoparticle encapsulation improves oral bioavailability of curcumin by at least 9-fold when compared to curcumin administered with piperine as absorption enhancer. Eur J Pharm Sci 37, 223-230 (2009).
22. Yallapu, M. M., Gupta, B. K., Jaggi, M. & Chauhan, S. C. Fabrication of curcumin encapsulated PLGA nanoparticles for improved therapeutic effects in metastatic cancer cells. J Colloid Interface Sci 351, 19-29 (2010).
23. Wang, W. et al. MicroRNA-21 and the clinical outcomes of various carcinomas: a systematic review and meta-analysis. BMC Cancer 14, 819 (2014).
24. Garajova, I. et al. Molecular mechanisms underlying the role of microRNAs in the chemoresistance of pancreatic cancer. Biomed Res Int 2014, 678401 (2014).
25. Wang, F., Liu, M., Li, X. & Tang, H. MiR-214 reduces cell survival and enhances cisplatin-induced cytotoxicity via down-regulation of Bcl2l2 in cervical cancer cells. FEBS Lett 587, 488-495 (2013).
26. Qiang, R. et al. Plexin-B1 is a target of miR-214 in cervical cancer and promotes the growth and invasion of HeLa cells. Int J Biochem Cell Biol 43, 632-641 (2011).
27. Meissner, J. D. Nucleotide sequences and further characterization of human papillomavirus DNA present in the CaSki, SiHa and HeLa cervical carcinoma cell lines. J Gen Virol 80(Pt 7), 1725-1733 (1999).
28. Adler, K., Erickson, T. & Bobrow, M. High sensitivity detection of HPV-16 in SiHa and CaSki cells utilizing FISH enhanced by TSA. Histochem Cell Biol 108, 321-324 (1997).
29. Saavedra, K. P., Brebi, P. M. & Roa, J. C. Epigenetic alterations in preneoplastic and neoplastic lesions of the cervix. Clin Epigenetics 4, 13 (2012).
30. Keating, J. T. et al. Ki-67, cyclin E, and p16INK4 are complimentary surrogate biomarkers for human papilloma virus-related cervical neoplasia. Am J Surg Pathol 25, 884-891 (2001).
31. Loffler, D. et al. Interleukin-6 dependent survival of multiple myeloma cells involves the Stat3-mediated induction of microRNA-21 through a highly conserved enhancer. Blood 110, 1330-1333 (2007).
32. Wang, X. et al. MiR-214 inhibits cell growth in hepatocellular carcinoma through suppression of beta-catenin. Biochem Biophys Res Commun 428, 525-531 (2012).
33. Xu, L. F. et al. MicroRNA-21 (miR-21) regulates cellular proliferation, invasion, migration, and apoptosis by targeting PTEN, RECK and Bcl-2 in lung squamous carcinoma, Gejiu City, China. PLoS One 9, e103698 (2014).
34. Shen, H. et al. Alteration in Mir-21/PTEN expression modulates gefitinib resistance in non-small cell lung cancer. PLoS One 9, e103305 (2014).
35. Ross, A. H. & Gericke, A. Phosphorylation keeps PTEN phosphatase closed for business. Proc Natl Acad Sci USA 106, 1297-1298 (2009).
36. Maccario, H., Perera, N. M., Davidson, L., Downes, C. P. & Leslie, N. R. PTEN is destabilized by phosphorylation on Thr366. Biochem J 405, 439-444 (2007).
37. Xia, H., Ooi, L. L. & Hui, K. M. MiR-214 targets beta-catenin pathway to suppress invasion, stem-like traits and recurrence of human hepatocellular carcinoma. PLoS One 7, e44206 (2012).
38. Wang, Y., Zhai, W., Wang, H., Xia, X. & Zhang, C. Benzo(a)pyrene promotes A549 cell migration and invasion through upregulating Twist. Arch Toxicol, 89(3), 451-458 (2015).
39. Castillo-Sanchez, R., Villegas-Comonfort, S., Galindo-Hernandez, O., Gomez, R. & Salazar, E. P. Benzo-[a]-pyrene induces FAK activation and cell migration in MDA-MB-231 breast cancer cells. Cell Biol Toxicol 29, 303-319 (2013).
40. Yoshino, I. et al. Induction of epithelial-mesenchymal transition-related genes by benzo[a]pyrene in lung cancer cells. Cancer 110, 369-374 (2007).
41. Li, F., Wang, T. & Tang, S. SOX14 promotes proliferation and invasion of cervical cancer cells through Wnt/β-catenin pathway. Int J Clin Exp Pathol 8(2), 1698-1704 (2015).
42. Polakis, P. The many ways of Wnt in cancer. Curr Opin Genet Dev 17, 45-51 (2007).
43. MacDonald, B. T., Tamai, K. & He, X. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 17, 9-26 (2009).
44. Henderson, B. R. & Fagotto, F. The ins and outs of APC and beta-catenin nuclear transport. EMBO Rep 3, 834-839 (2002).
45. Cadigan, K. M. & Peifer, M. Wnt signaling from development to disease: insights from model systems. Cold Spring Harb Perspect Biol 1, a002881 (2009).
46. Jamieson, C., Sharma, M. & Henderson, B. R. Wnt signaling from membrane to nucleus: beta-catenin caught in a loop. Int J Biochem Cell Biol 44, 847-850 (2012).
47. McGraw, S. L. & Ferrante, J. M. Update on prevention and screening of cervical cancer. World J Clin Oncol 5, 744-752 (2014).
48. Schiffman, M., Castle, P. E., Jeronimo, J., Rodriguez, A. C. & Wacholder, S. Human papillomavirus and cervical cancer. Lancet 370, 890-907 (2007).
49. McIntyre-Seltman, K., Castle, P. E., Guido, R., Schiffman, M., Wheeler, C. M. & Group, A. Smoking is a risk factor for cervical intraepithelial neoplasia grade 3 among oncogenic human papillomavirus DNA-positive women with equivocal or mildly abnormal cytology. Cancer Epidemiol Biomarkers Prev 14, 1165-1170 (2005).
50. Izzotti, A. et al. Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke. FASEB J 23, 806-812 (2009).
51. Schembri, F. et al. MicroRNAs as modulators of smoking-induced gene expression changes in human airway epithelium. Proc Natl Acad Sci USA 106, 2319-2324 (2009).
52. Chen, W. et al. Low-dose gamma-irradiation inhibits IL-6 secretion from human lung fibroblasts that promotes bronchial epithelial cell transformation by cigarette-smoke carcinogen. Carcinogenesis 33, 1368-1374 (2012).
53. Pei, X. H. et al. Polycyclic aromatic hydrocarbons induce IL-8 expression through nuclear factor kappaB activation in A549 cell line. Cytokine 19, 236-241 (2002).
54. Volinia, S. et al. A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 103, 2257-2261 (2006).
55. Shin, V. Y. et al. NF-kappaB targets miR-16 and miR-21 in gastric cancer: involvement of prostaglandin E receptors. Carcinogenesis 32, 240-245 (2011).
56. Zhou, R., Hu, G., Gong, A. Y. & Chen, X. M. Binding of NF-kappaB p65 subunit to the promoter elements is involved in LPSinduced transactivation of miRNA genes in human biliary epithelial cells. Nucleic Acids Res 38, 3222-3232 (2010).
57. Di, G. H. et al. IL-6 secreted from senescent mesenchymal stem cells promotes proliferation and migration of breast cancer cells. PLoS One 9, e113572 (2014).
58. Sun, W. et al. Interleukin-6 promotes the migration and invasion of nasopharyngeal carcinoma cell lines and upregulates the expression of MMP-2 and MMP-9. Int J Oncol 44, 1551-1560 (2014).
59. Heinecke, J. L. et al. Tumor microenvironment-based feed-forward regulation of NOS2 in breast cancer progression. Proc Natl Acad Sci USA 111, 6323-6328 (2014).
60. Punfa, W., Yodkeeree, S., Pitchakarn, P., Ampasavate, C. & Limtrakul, P. Enhancement of cellular uptake and cytotoxicity of curcumin-loaded PLGA nanoparticles by conjugation with anti-P-glycoprotein in drug resistance cancer cells. Acta Pharmacol Sin 33(6), 823-31 (2012).