Inhibition of miR-222-3p activity promoted osteogenic differentiation of hBMSCs by regulating Smad5-RUNX2 signal axis

Biochemical and Biophysical Research Communications

Volumn 470, Issue 3, 2016, Pages 498-503

  Yan, Jihong ^a   Guo, Duo ^a   Yang, Shu ^a   Sun, Huaimei ^a   Wu, Bo ^a   Zhou, Deshan ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Mesenchymal stem cells; miR 222 3p; Osteogenic differentiation; RUNX2; Smad5

Indexed keywords

ALKALINE PHOSPHATASE; LENTIVIRUS VECTOR; MICRORNA; MICRORNA 222 3P; MICRORNA 222 3P INHIBITOR; PROTEIN INHIBITOR; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; MIRN222 MICRORNA, HUMAN; RUNX2 PROTEIN, HUMAN; SMAD5 PROTEIN, HUMAN;

ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; CELL CULTURE; CYTOLOGY; GENE EXPRESSION REGULATION; MESENCHYMAL STROMA CELL; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MESENCHYMAL STROMAL CELLS; MICRORNAS; OSTEOBLASTS; OSTEOGENESIS; SIGNAL TRANSDUCTION; SMAD5 PROTEIN;

EID: 84957581149     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2016.01.133     Document Type: Article

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