RACK1 promotes maintenance of morphine-associated memory via activation of an ERK-CREB dependent pathway in hippocampus

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Liu, Litao ^a   Zhu, Jiejun ^a   Zhou, Liming ^a   Wan, Lihong ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GNB2-RS1 PROTEIN, MOUSE; MORPHINE; NEUROPEPTIDE; SMALL INTERFERING RNA;

ANIMAL; C57BL MOUSE; DRUG EFFECTS; HIPPOCAMPUS; INSTRUMENTAL CONDITIONING; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MALE; MEMORY; METABOLISM; NERVE CELL PLASTICITY; REWARD; SIGNAL TRANSDUCTION; SYNAPSE; ULTRASTRUCTURE; UPREGULATION;

ANIMALS; CONDITIONING, OPERANT; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; HIPPOCAMPUS; INJECTIONS, INTRAVENTRICULAR; MALE; MAP KINASE SIGNALING SYSTEM; MEMORY; MICE, INBRED C57BL; MORPHINE; NEURONAL PLASTICITY; NEUROPEPTIDES; RECEPTORS, CELL SURFACE; REWARD; RNA, SMALL INTERFERING; SYNAPSES; UP-REGULATION;

EID: 84957536870     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep20183     Document Type: Article

References (40)

1. Compton, W. M. & Volkow, N. D. Major increases in opioid analgesicabuse in the United States: concerns and strategies. Drug Alcohol Depend 81, 103-107 (2006).
2. Childress, A. R. et al. Limbic activation during cue-induced cocaine craving. Am J Psychiatry 156, 11-18 (1999).
3. Dennis, M. & Scott, C. K. Managing addiction as a chronic condition. Addict Sci Clin Pract 4, 45-55 (2007).
4. Childress, A., Ehrman, R., McLellan, A. T. & O'Brien, C. Conditioned craving and arousal in cocaine addiction: a preliminary report. NIDA Res Monogr 81, 74-80 (1988).
5. Wu, W. et al. Involvement of insular muscarinic cholinergic receptors in morphine-induced conditioned place preference in rats. Psychopharmacology (Berl) 231, 4109-18 (2014).
6. Squire, L. R. Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans. Psychol Rev 99, 195-231 (1992).
7. Isokawa, M. Cellular signal mechanisms of reward-related plasticity in the hippocampus. Neural Plast 2012, 945373 (2012).
8. Heidari, M. H. et al. Effect of chronic morphine consumption on synaptic plasticity of rat's hippocampus: a transmission electron microscopy study. Neurol Res Int 2013, 290414 (2013).
9. Portugal, G. S. et al. Hippocampal long-term potentiation is disrupted during expression and extinction but is restored after reinstatement of morphine place preference. J Neurosci 34, 527-38 (2014).
10. Yaka, R. et al. NMDA receptor function is regulated by the inhibitory scaffolding protein, RACK1. Proc Natl AcadSci USA 99, 5710-5 (2002).
11. Yaka, R., He, D. Y., Phamluong, K. & Ron, D. Pituitary adenylate cyclase-activating polypeptide (PACAP(1-38)) enhances N-methyl-D-aspartate receptor function and brain-derived neurotrophic factor expression via RACK1. J Biol Chem 278, 9630-8 (2003).
12. Arimoto, K. et al. Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways. Nat Cell Biol 10, 1324-32(2008).
13. Sklan, E. H., Podoly, E. & Soreq, H. RACK1 has the nerve to act: structure meets function in the nervous system. Prog Neurobiol 78, 117-34 (2006).
14. He, D. Y., Neasta, J. & Ron, D. Epigenetic regulation of BDNF expression via the scaffolding protein RACK1. J Biol Chem 285, 19043-50 (2010).
15. Wan, L. et al. Protein receptor for activated C kinase 1 is involved in morphine reward in mice. Neuroscience 161, 734-42 (2009).
16. Wan, L. et al. RACK1 affects morphine reward via BDNF. Brain Res 1416, 26-34 (2011).
17. Russo, S. J., Mazei-Robison, M. S., Ables, J. L. & Nestler, E. J. Neurotrophic factors and structural plasticity in addiction. Neuropharmacology 56, 73-82 (2009).
18. Di Benedetto, B. et al. Differential mRNA distribution of components of the ERK/MAPK signaling cascade in the adult mouse brain. J Comp Neurol 500, 542-56 (2007).
19. Xu, Y. et al. Essential role of NR2B-containing NMDA receptor-ERK pathway in nucleus accumbens shell in morphine-associated contextual memory. Brain Res Bull 89, 22-30 (2012).
20. Agoglia, A. E. et al. Alcohol Alters the activation of ERK1/2, a functional regulator of binge alcohol drinking in adult C57BL/6J mice. Alcohol Clin Exp Res 39, 463-75 (2015).
21. Morón, J. A. et al. Modulation of opiate-related signaling molecules in morphine-dependent conditioned behavior: conditioned place preference to morphine induces CREB phosphorylation. Neuropsychopharmacology 35, 955-66 (2010).
22. Krasnova, I. N. et al. CREB phosphorylation regulates striatal transcriptional responses in the self-administration model of methamphetamine addiction in the rat. Neurobiol Dis 58, 132-43 (2013).
23. Calhoun, M. E. et al. Comparative evaluation of synaptophysin-based methods for quantification of synapses. J Neurocytol 25, 821-828 (1996).
24. Kim, S. Y. et al. Experience with the "good" limb induces aberrant synaptic plasticity in the perilesion cortex after stroke. J Neurosci 35, 8604-10 (2015).
25. Lu, L., Zeng, S., Liu, D. & Ceng, X. Inhibition of the amygdala and hippocampal calcium/calmodulin-dependent protein kinase II attenuates the dependence and relapse to morphine differently in rats. Neurosci Lett 291, 191-5 (2000).
26. Zhang, X. Q. et al. Activation of p38 signaling in the microglia in the nucleus accumbens contributes to the acquisition and maintenance of morphine-induced conditioned place preference. Brain Behav Immun 26, 318-25 (2012).
27. Lüscher, C. & Malenka, R. C. Drug-evoked synaptic plasticity in addiction: from molecular changes to circuit remodeling. Neuron 69, 650-63 (2011).
28. Lüscher, C. Drug-evoked synaptic plasticity causing addictive behavior. J Neurosci 33, 17641-6 (2013).
29. Alaghband, Y. et al. Retrieval-induced NMDA receptor-dependentArc expression in two models of cocaine-cue memory. Neurobiol Learn Mem 116, 79-89 (2014).
30. Martin, S. J., Grimwood, P. D. & Morris, R. G. Synaptic plasticity and memory: an evaluation of the hypothesis. Annu Rev Neurosci 23, 649-711 (2000).
31. Bennett, M. K. & Scheller, R. H. Themolecular machinery for secretion is conserved from yeast to neurons. Proc Natl AcadSci USA 90, 2559-2563 (1993).
32. Tarsa, L. & Goda, Y. Synaptophysin regulates activity-dependent synapse formation in cultured hippocampal neurons. Proc Natl AcadSci USA 99, 1012-1016 (2002).
33. Yong, Z. et al. Effects of thienorphine on synaptic structure and synaptophysin expression in the rat nucleus accumbens. Neuroscience 274, 53-8 (2014).
34. Yong, Z. et al. The effect of chronic thienorphine administration on long-term potentiation and synaptic structure in rat hippocampus. Synapse 67, 779-85 (2013).
35. Allen, K. D. et al. Nucleolar integrity is required for the maintenance of long-term synaptic plasticity. PLoS One 9, e104364 (2014).
36. Liu, Y. et al. The extracellular signal-regulated kinase signaling pathway is involved in the modulation of morphine-induced reward by mPer1. Neuroscience 146, 265-271 (2007).
37. Kim, S. W. et al. Memory-improving effect of formulation-MSS by activation of hippocampal MAPK/ERK signaling pathway in rats. BMB Rep 41, 242-7 (2008).
38. Ma, W. et al. Chronic morphine exposure increases the phosphorylation of MAP kinases and the transcription factor CREB in dorsal root ganglion neurons: an in vitro and in vivo study. Eur J Neurosci 14, 1091-104 (2001).
39. Li, S. X. et al. Inhibition of Period1 gene attenuates the morphine-induced ERK-CREB activation in frontal cortex, hippocampus, and striatum in mice. Am J Drug Alcohol Abuse 34, 673-82 (2008).
40. Lv, X. F. et al. NAc shell Arc/Arg3.1 protein mediates reconsolidation of morphine CPP by increased GluR1 cell surface expression: activation of ERK-coupled CREB is required. Int J Neuropsychopharmacol 18, doi: 10.1093/ijnp/pyv030 (2015).