MiRNA-486 regulates angiogenic activity and survival of mesenchymal stem cells under hypoxia through modulating Akt signal

Biochemical and Biophysical Research Communications

Volumn 470, Issue 3, 2016, Pages 670-677

  Shi, Xue Feng ^a,b,c   Wang, Hua ^b   Xiao, Feng Jun ^b   Yin, Yue ^b,d   Xu, Qin Qin ^a,b   Ge, Ri Li ^a   Wang, Li Sheng ^b  

^a QINGHAI UNIVERSITY   (China)

^b BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^c Department of Respiratory Medicine Qinghai Provincial People s Hospital   (China)

^d PEKING UNIVERSITY FIRST HOSPITAL   (China)

Author keywords

Bone marrow mesenchymal stem cells; Hypoxia; miR 486; PTEN PI3K AKT signaling

Indexed keywords

MESSENGER RNA; MICRORNA; MICRORNA 486; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; SCATTER FACTOR; UNCLASSIFIED DRUG; VASCULOTROPIN; ANGIOGENIC PROTEIN; MIRN486 MICRORNA, HUMAN; ONCOPROTEIN; OXYGEN;

ANGIOGENESIS; APOPTOSIS; ARTICLE; CELL HYPOXIA; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; UPREGULATION; CELL CULTURE; CELL DIFFERENTIATION; CELL MOTION; CYTOLOGY; MESENCHYMAL STROMA CELL; METABOLISM; PHYSIOLOGY;

ANGIOGENIC PROTEINS; CELL DIFFERENTIATION; CELL HYPOXIA; CELL MOVEMENT; CELL SURVIVAL; CELLS, CULTURED; GENE EXPRESSION REGULATION; HUMANS; MESENCHYMAL STROMAL CELLS; MICRORNAS; NEOVASCULARIZATION, PHYSIOLOGIC; ONCOGENE PROTEIN V-AKT; OXYGEN; SIGNAL TRANSDUCTION;

EID: 84957438057     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2016.01.084     Document Type: Article

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