Circadian clock gene aryl hydrocarbon receptor nuclear translocator-like polymorphisms are associated with seasonal affective disorder: An Indian family study

Indian Journal of Psychiatry

Volumn 58, Issue 1, 2016, Pages 57-60

  Rajendran, Bhagya ^a   Janakarajan, Veeramahali Natarajan ^b  

^a BHARATHIAR UNIVERSITY   (India)

^b Department of Pharmacology   (India)

Author keywords

Aryl hydrocarbon receptor nuclear translocator like; circadian rhythms; seasonal affective disorder; single nucleotide polymorphism

Indexed keywords

TRANSCRIPTION FACTOR ARNTL;

ALLELE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FAMILY STUDY; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HUMAN; INDIAN; PATHOGENESIS; SEASONAL AFFECTIVE DISORDER; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 84957111035     PISSN: 00195545     EISSN: 19983794     Source Type: Journal    
DOI: 10.4103/0019-5545.174374     Document Type: Article

References (20)

1. Rosenthal NE, Sack DA, Gillin JC, Lewy AJ, Goodwin FK, Davenport Y, et al. Seasonal affective disorder. A description of the syndrome and preliminary findings with light therapy. Arch Gen Psychiatry 1984;41:72-80.
2. Le-Niculescu H, Patel SD, Bhat M, Kuczenski R, Faraone SV, Tsuang MT, et al. Convergent functional genomics of genome-wide association data for bipolar disorder: Comprehensive identification of candidate genes, pathways and mechanisms. Am J Med Genet B Neuropsychiatr Genet 2009;150B: 155-81.
3. Bunger MK, Wilsbacher LD, Moran SM, Clendenin C, Radcliffe LA, Hogenesch JB, et al. Mop3 is an essential component of the master circadian pacemaker in mammals. Cell 2000;103:1009-17.
4. Mansour HA, Wood J, Logue T, Chowdari KV, Dayal M, Kupfer DJ, et al. Association study of eight circadian genes with bipolar I disorder, schizoaffective disorder and schizophrenia. Genes Brain Behav 2006;5:150-7.
5. Nievergelt CM, Kripke DF, Barrett TB, Burg E, Remick RA, Sadovnick AD, et al. Suggestive evidence for association of the circadian genes PERIOD3 and ARNTL with bipolar disorder. Am J Med Genet B Neuropsychiatr Genet 2006;141B: 234-41.
6. Partonen T, Treutlein J, Alpman A, Frank J, Johansson C, Depner M, et al. Three circadian clock genes Per2, Arntl, and Npas2 contribute to winter depression. Ann Med 2007;39:229-38.
7. Patel SD, Le-Niculescu H, Koller DL, Green SD, Lahiri DK, McMahon FJ, et al. Coming to grips with complex disorders: Genetic risk prediction in bipolar disorder using panels of genes identified through convergent functional genomics. Am J Med Genet B Neuropsychiatr Genet 2010;153B: 850-77.
8. Soria V, Martínez-Amorós E, Escaramís G, Valero J, Pérez-Egea R, García C, et al. Differential association of circadian genes with mood disorders: CRY1 and NPAS2 are associated with unipolar major depression and CLOCK and VIP with bipolar disorder. Neuropsychopharmacology 2010;35:1279-89.
9. McCarthy MJ, Nievergelt CM, Kelsoe JR, Welsh DK. A survey of genomic studies supports association of circadian clock genes with bipolar disorder spectrum illnesses and lithium response. PLoS One 2012;7:e32091.
10. Thornton T, Zhang Q, Cai X, Ober C, McPeek MS. XM: Association testing on the X-chromosome in case-control samples with related individuals. Genet Epidemiol 2012;36:438-50.
11. Thornton T, McPeek MS. Case-control association testing with related individuals: A more powerful quasi-likelihood score test. Am J Hum Genet 2007;81:321-37.
12. Bourgain C, Hoffjan S, Nicolae R, Newman D, Steiner L, Walker K, et al. Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus. Am J Hum Genet 2003;73:612-26.
13. Baum AE, Akula N, Cabanero M, Cardona I, Corona W, Klemens B, et al. A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder. Mol Psychiatry 2008;13:197-207.
14. Geoffroy PA, Lajnef M, Bellivier F, Jamain S, Gard S, Kahn JP, et al. Genetic association study of circadian genes with seasonal pattern in bipolar disorders. Sci Rep 2015;5:10232.
15. Kovanen L, Saarikoski ST, Aromaa A, Lönnqvist J, Partonen T. ARNTL (BMAL1) and NPAS2 gene variants contribute to fertility and seasonality. PLoS One 2010;5:e10007.
16. Magnusson A, Partonen T. The diagnosis, symptomatology, and epidemiology of seasonal affective disorder. CNS Spectr 2005;10:625-34.
17. Greenwood TA, Schork NJ, Eskin E, Kelsoe JR. Identification of additional variants within the human dopamine transporter gene provides further evidence for an association with bipolar disorder in two independent samples. Mol Psychiatry 2006;11:125-33, 115.
18. Berk M, Dodd S, Kauer-Sant'anna M, Malhi GS, Bourin M, Kapczinski F, et al. Dopamine dysregulation syndrome: Implications for a dopamine hypothesis of bipolar disorder. Acta Psychiatr Scand Suppl 2007;434:41-9.
19. Hampp G, Ripperger JA, Houben T, Schmutz I, Blex C, Perreau-Lenz S, et al. Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood. Curr Biol 2008;18:678-83.
20. Huang ZJ, Edery I, Rosbash M. PAS is a dimerization domain common to Drosophila period and several transcription factors. Nature 1993;364:259-62.