-
1
-
-
77950610036
-
The changing demographic pattern of multiple sclerosis epidemiology
-
Koch-Henriksen N, Sorensen PS,. The changing demographic pattern of multiple sclerosis epidemiology. Lancet Neurol 2010; 9: 520-532.
-
(2010)
Lancet Neurol
, vol.9
, pp. 520-532
-
-
Koch-Henriksen, N.1
Sorensen, P.S.2
-
2
-
-
84555197737
-
A mechanistically novel, first oral therapy for multiple sclerosis: The development of fingolimod (FTY720, Gilenya)
-
Chun J, Brinkmann V,. A mechanistically novel, first oral therapy for multiple sclerosis: the development of fingolimod (FTY720, Gilenya). Discov Med 2011; 12: 213-228.
-
(2011)
Discov Med
, vol.12
, pp. 213-228
-
-
Chun, J.1
Brinkmann, V.2
-
3
-
-
76149093586
-
A placebo controlled trial of oral fingolimod in relapsing multiple sclerosis
-
Kappos L, Radue EW, O'Connor P, et al. A placebo controlled trial of oral fingolimod in relapsing multiple sclerosis. N Engl J Med 2010; 362: 387-401.
-
(2010)
N Engl J Med
, vol.362
, pp. 387-401
-
-
Kappos, L.1
Radue, E.W.2
O'Connor, P.3
-
4
-
-
84901197534
-
Safety and efficacy of fingolimod in patients with relapsing-remitting multiple sclerosis (FREEDOMS II): A double-blind, randomised, placebo-controlled, phase 3 trial
-
Erratum: Lancet Neurol 2013; 13: 536
-
Calabresi PA, Radue EW, Goodin D, et al. Safety and efficacy of fingolimod in patients with relapsing-remitting multiple sclerosis (FREEDOMS II): a double-blind, randomised, placebo-controlled, phase 3 trial. Lancet Neurol 2014; 13: 545-56; Erratum: Lancet Neurol 2013; 13: 536.
-
(2014)
Lancet Neurol
, vol.13
, pp. 545-556
-
-
Calabresi, P.A.1
Radue, E.W.2
Goodin, D.3
-
5
-
-
76149140914
-
Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis
-
Cohen JA, Barkhof F, Comi G, et al. Oral fingolimod or intramuscular interferon for relapsing multiple sclerosis. N Engl J Med 2010; 362: 402-415.
-
(2010)
N Engl J Med
, vol.362
, pp. 402-415
-
-
Cohen, J.A.1
Barkhof, F.2
Comi, G.3
-
6
-
-
77951073508
-
Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis
-
Chun J, Hartung HP,. Mechanism of action of oral fingolimod (FTY720) in multiple sclerosis. Clin Neuropharmacol 2010; 33: 91-101.
-
(2010)
Clin Neuropharmacol
, vol.33
, pp. 91-101
-
-
Chun, J.1
Hartung, H.P.2
-
7
-
-
70849086174
-
FTY720 (fingolimod) in multiple sclerosis: Therapeutic effects in the immune and the central nervous system
-
Brinkmann V,. FTY720 (fingolimod) in multiple sclerosis: therapeutic effects in the immune and the central nervous system. Br J Pharmacol 2009; 158: 1173-1182.
-
(2009)
Br J Pharmacol
, vol.158
, pp. 1173-1182
-
-
Brinkmann, V.1
-
8
-
-
33747419124
-
Pulmonary and vascular pharmacology of sphingosine 1-phosphate
-
Brinkmann V, Baumruker T,. Pulmonary and vascular pharmacology of sphingosine 1-phosphate. Curr Opin Pharmacol 2006; 6: 244-250.
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 244-250
-
-
Brinkmann, V.1
Baumruker, T.2
-
9
-
-
0036239322
-
Cell type-specific localization of human cardiac S1P receptors
-
Mazurais D, Roberts P, Gout B, et al. Cell type-specific localization of human cardiac S1P receptors. J Histochem Cytochem 2002; 50: 661-669.
-
(2002)
J Histochem Cytochem
, vol.50
, pp. 661-669
-
-
Mazurais, D.1
Roberts, P.2
Gout, B.3
-
10
-
-
0035310611
-
Sphingosylphosphocholine is a naturally occurring lipid mediator in blood plasma: A possible role in regulating cardiac function via sphingolipid receptors
-
Liliom K, Sun G, Bunemann M, et al. Sphingosylphosphocholine is a naturally occurring lipid mediator in blood plasma: a possible role in regulating cardiac function via sphingolipid receptors. Biochem J 2001; 355: 189-197.
-
(2001)
Biochem J
, vol.355
, pp. 189-197
-
-
Liliom, K.1
Sun, G.2
Bunemann, M.3
-
11
-
-
14644408845
-
The heart rate decrease caused by acute FTY720 administration is mediated by the G protein-gated potassium channel i
-
Koyrakh L, Roman MI, Brinkmann V, et al. The heart rate decrease caused by acute FTY720 administration is mediated by the G protein-gated potassium channel I. Am J Transplant 2005; 5: 529-536.
-
(2005)
Am J Transplant
, vol.5
, pp. 529-536
-
-
Koyrakh, L.1
Roman, M.I.2
Brinkmann, V.3
-
12
-
-
33745927144
-
FTY720: Placebo-controlled study of the effect on cardiac rate and rhythm in healthy subjects
-
Schmouder R, Serra D, Wang Y, et al. FTY720: placebo-controlled study of the effect on cardiac rate and rhythm in healthy subjects. J Clin Pharmacol 2006; 46: 895-904.
-
(2006)
J Clin Pharmacol
, vol.46
, pp. 895-904
-
-
Schmouder, R.1
Serra, D.2
Wang, Y.3
-
13
-
-
79952034469
-
Long-term safety of oral fingolimod (FTY720) in relapsing multiple sclerosis: Integrated analyses of phase 1 and 3 studies (P843)
-
Collins W, Cohen J, O'Connor P, et al. Long-term safety of oral fingolimod (FTY720) in relapsing multiple sclerosis: integrated analyses of phase 1 and 3 studies (P843). Mult Scler 2010; 16: S295.
-
(2010)
Mult Scler
, vol.16
, pp. S295
-
-
Collins, W.1
Cohen, J.2
O'Connor, P.3
-
14
-
-
84957088865
-
Intermittent atrioventricular block following fingolimod initiation
-
Gialafos E, Gerakoulis S, Grigoriou A, et al. Intermittent atrioventricular block following fingolimod initiation. Case Rep Neurol Med 2014: 1-4. DOI: 10.1155/2014/191305.
-
(2014)
Case Rep Neurol Med
, pp. 1-4
-
-
Gialafos, E.1
Gerakoulis, S.2
Grigoriou, A.3
-
15
-
-
84856249964
-
Fingolimod for multiple sclerosis
-
Pelletier D, Hafler DA,. Fingolimod for multiple sclerosis. N Engl J Med 2012; 366: 339-347.
-
(2012)
N Engl J Med
, vol.366
, pp. 339-347
-
-
Pelletier, D.1
Hafler, D.A.2
-
16
-
-
80655128161
-
Delayed fingolimod-associated asystole
-
Espinosa PS, Berger JR,. Delayed fingolimod-associated asystole. Mult Scler 2011; 17: 1387-1389.
-
(2011)
Mult Scler
, vol.17
, pp. 1387-1389
-
-
Espinosa, P.S.1
Berger, J.R.2
-
18
-
-
84860706754
-
-
European Medicines Agency. (accessed 25 October 2012)
-
European Medicines Agency. European Medicines Agency starts review of Gilenya (fingolimod). 2012. http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/public-health-alerts/2012/01/human-pha-detail-000050.jsp&mid=WC0b01ac058001d126 (. accessed 25 October 2012).
-
(2012)
European Medicines Agency Starts Review of Gilenya (Fingolimod)
-
-
-
19
-
-
84899660109
-
EAP Investigators. Safety of the first dose of fingolimod for multiple sclerosis: Results of an open-label clinical trial
-
Laroni A, Brogi D, Morra VB, et al. EAP Investigators. Safety of the first dose of fingolimod for multiple sclerosis: results of an open-label clinical trial. BMC Neurol 2014; 14: 65.
-
(2014)
BMC Neurol
, vol.14
, pp. 65
-
-
Laroni, A.1
Brogi, D.2
Morra, V.B.3
-
20
-
-
84902664210
-
Overview and safety of fingolimod hydrochloride use in patients with multiple sclerosis
-
Ward MD, Jones DE, Goldman MD,. Overview and safety of fingolimod hydrochloride use in patients with multiple sclerosis. Expert Opin Drug Saf 2014; 13: 989-98.
-
(2014)
Expert Opin Drug Saf
, vol.13
, pp. 989-998
-
-
Ward, M.D.1
Jones, D.E.2
Goldman, M.D.3
-
21
-
-
84923093812
-
The autonomic balance predicts cardiac responses after the first dose of fingolimod
-
Rossi S, Rocchi C, Studer V, et al. The autonomic balance predicts cardiac responses after the first dose of fingolimod. Mult Scler 2015; 21: 206-216.
-
(2015)
Mult Scler
, vol.21
, pp. 206-216
-
-
Rossi, S.1
Rocchi, C.2
Studer, V.3
-
22
-
-
0024723470
-
Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms
-
Schiller NB, Shah PM, Crawford M, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms. J Am Soc Echocardiogr 1989; 2: 358-367.
-
(1989)
J Am Soc Echocardiogr
, vol.2
, pp. 358-367
-
-
Schiller, N.B.1
Shah, P.M.2
Crawford, M.3
-
23
-
-
0036481560
-
Doppler Quantification Task Force of the Nomenclature and Standards Committee of the American Society of Echocardiography. Recommendations for quantification of Doppler echocardiography: A report from the Doppler Quantification Task Force of the Nomenclature and Standards Committee of the American Society of Echocardiography
-
Quiñones MA, Otto CM, Stoddard M, et al. Doppler Quantification Task Force of the Nomenclature and Standards Committee of the American Society of Echocardiography. Recommendations for quantification of Doppler echocardiography: a report from the Doppler Quantification Task Force of the Nomenclature and Standards Committee of the American Society of Echocardiography. J Am Soc Echocardiogr 2002; 15: 167-184.
-
(2002)
J Am Soc Echocardiogr
, vol.15
, pp. 167-184
-
-
Quiñones, M.A.1
Otto, C.M.2
Stoddard, M.3
-
24
-
-
84880792302
-
Safety, tolerability, and efficacy of oral therapies for relapsing-remitting multiple sclerosis
-
Oh J, O'Connor PW,. Safety, tolerability, and efficacy of oral therapies for relapsing-remitting multiple sclerosis. CNS Drugs 2013; 27: 591-609.
-
(2013)
CNS Drugs
, vol.27
, pp. 591-609
-
-
Oh, J.1
O'Connor, P.W.2
-
25
-
-
84860284278
-
Placebo-controlled study of the effects of fingolimod on cardiac rate and rhythm and pulmonary function in healthy volunteers
-
Schmouder R, Hariry S, David OJ,. Placebo-controlled study of the effects of fingolimod on cardiac rate and rhythm and pulmonary function in healthy volunteers. Eur J Clin Pharmacol 2012; 68: 355-362.
-
(2012)
Eur J Clin Pharmacol
, vol.68
, pp. 355-362
-
-
Schmouder, R.1
Hariry, S.2
David, O.J.3
|