A novel photoelectrochemical immunosensor by integration of nanobody and TiO2 nanotubes for sensitive detection of serum cystatin C

Analytica Chimica Acta

Volumn 902, Issue , 2016, Pages 107-114

  Mi, Li ^a   Wang, Pingyan ^b   Yan, Junrong ^b   Qian, Jing ^a   Lu, Jusheng ^a   Yu, Jiachao ^a   Wang, Yuzhen ^d   Liu, Hong ^d   Zhu, Min ^b   Wan, Yakun ^b,c   Liu, Songqin ^a  

^a SOUTHEAST UNIVERSITY   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c Jiangsu Nanobody Engineering and Research Center   (China)

^d Plexera LLC   (United States)

Author keywords

Covalence; Cystatin C; Nanobody; Photoelectrochemical immunosensor; TiO2 nanotube arrays

Indexed keywords

CORRELATION DETECTORS; DIAGNOSIS; ELECTROCHEMISTRY; IMMUNOSENSORS; PHOTOCURRENTS; SIGNAL TO NOISE RATIO; TITANIUM DIOXIDE; YARN;

COVALENCE; CYSTATIN C; NANOBODY; NANOTUBE ARRAYS; PHOTOELECTROCHEMICALS;

NANOTUBES;

BOVINE SERUM ALBUMIN; CYSTATIN C; CYSTATIN C SPECIFIC NANOBODY; CYSTATIN C SPECIFIC NANOBODY TIO2 NANOTUBE; NANOBODY; NANOTUBE; TIO2 NANOTUBE; UNCLASSIFIED DRUG; TITANIUM; TITANIUM DIOXIDE;

ACCURACY; ARTICLE; BACTRIAN CAMEL; BINDING AFFINITY; CALIBRATION; CONTROLLED STUDY; COVALENT BOND; ELECTROCHEMICAL ANALYSIS; ELECTROCHEMICAL ANODIZATION; IMMUNOSENSOR; LIMIT OF DETECTION; NONHUMAN; PHAGE DISPLAY; PHOTOELECTROCHEMICAL IMMUNOSENSOR; PRIORITY JOURNAL; PROTEIN ANALYSIS; RELIABILITY; SENSITIVITY AND SPECIFICITY; SIGNAL NOISE RATIO; THERMOSTABILITY; BLOOD; CHEMISTRY; ELECTROCHEMISTRY; GENETIC PROCEDURES; HUMAN; PHOTOCHEMISTRY; SCANNING ELECTRON MICROSCOPY; SURFACE PLASMON RESONANCE; TEMPERATURE;

BIOSENSING TECHNIQUES; CYSTATIN C; ELECTROCHEMISTRY; HUMANS; LIMIT OF DETECTION; MICROSCOPY, ELECTRON, SCANNING; NANOTUBES; PHOTOCHEMISTRY; SINGLE-DOMAIN ANTIBODIES; SURFACE PLASMON RESONANCE; TEMPERATURE; TITANIUM;

EID: 84956953467     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2015.11.007     Document Type: Article

References (46)

1. Stevens L.A., Coresh J., Greene T., Levey A.S. Medical progress - assessing kidney function - measured and estimated glomerular filtration rate. N. Engl. J. Med. 2006, 354:2473-2483.
2. Zappitelli M., Krawczeski C.D., Devarajan P., Wang Z., Sint K., Thiessen-Philbrook H., Li S.M., Bennett M.R., Ma Q., Shlipak M.G., Garg A.X., Parikh C.R. Early postoperative serum cystatin C predicts severe acute kidney injury following pediatric cardiac surgery. Kidney Int. 2011, 80:655-662. T.-A. Consortium.
3. Go A.S., Chertow G.M., Fan D.J., McCulloch C.E., Hsu C.Y. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N. Engl. J. Med. 2004, 351:1296-1305.
4. Menon V., Wang X., Sarnak M.J., Hunsicker L.H., Madero M., Beck G.J., Collins A.J., Kusek J.W., Levey A.S., Greene T. Long-term outcomes in nondiabetic chronic kidney disease. Kidney Int. 2008, 73:1310-1315.
5. Coca S.G., Parikh C.R. Urinary biomarkers for acute kidney injury: perspectives on translation. Clin. J. Am. Soc. Nephrol. 2008, 3:481-490.
6. Ichimura T., Hung C.C., Yang S.A., Stevens J.L., Bonventre J.V. Kidney injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced renal injury. Am. J. Physiol. Ren. 2004, 286:F552-F563.
7. Mishra J., Ma Q., Prada A., Mitsnefes M., Zahedi K., Yang J., Barasch J., Devarajan P. Identification of neutrophil gelatinase-associated lipocalin as a novel early urinary biomarker for ischemic renal injury. J. Am. Soc. Nephrol. 2003, 14:2534-2543.
8. Stevens L.A., Coresh J., Feldman H.I., Greene T., Lash J.P., Nelson R.G., Rahman M., Deysher A.E., Zhang Y.P., Schmid C.H., Levey A.S. Evaluation of the modification of diet in renal disease study equation in a large diverse population. J. Am. Soc. Nephrol. 2007, 18:2749-2757.
9. Schwartz G.J., Work D.F. Measurement and estimation of GFR in children and adolescents. Clin. J. Am. Soc. Nephrol. 2009, 4:1832-1843.
10. Bagshaw S.M., Bellomo R. Cystatin C in acute kidney injury. Curr. Opin. Crit. Care 2010, 16:533-539.
11. Shlipak M.G., Sarnak M.J., Katz R., Fried L.F., Seliger S.L., Newman A.B., Siscovick D.S., Stehman-Breen C. Cystatin C and the risk of death and cardiovascular events among elderly persons. N. Engl. J. Med. 2005, 352:2049-2060.
12. Peralta C.A., Shlipak M.G., Judd S., Cushman M., McClellan W., Zakai N.A., Safford M.M., Zhang X.A., Muntner P., Warnock D. Detection of chronic kidney disease with creatinine, cystatin C, and urine albumin-to-creatinine ratio and association with progression to end-stage renal disease and mortality. J. Am. Med. Assoc. 2011, 305:1545-1552.
13. Pergande M., Jung K. Sandwich enzyme-immunoassay of cystatin-C in serum with commercially available antibodies. Clin. Chem. 1993, 39:1885-1890.
14. Kyhseandersen J., Schmidt C., Nordin G., Andersson B., Nilssonehle P., Lindstrom V., Grubb A. Serum cystatin-C, determined by a rapid, automated particle-enhanced turbidimetric method, is a better marker than serum creatinine for glomerular-filtration rate. Clin. Chem. 1994, 40:1921-1926.
15. Harmsen M.M., De Haard H.J. Properties, production, and applications of camelid single-domain antibody fragments. Appl. Microbiol. Biot. 2007, 77:13-22.
16. Wang P.Y., Li G.H., Yan J.R., Hu Y.H., Zhang C.Z., Liu X.J., Wan Y.K. Bactrian camel nanobody-based immunoassay for specific and sensitive detection of Cry1Fa toxin. Toxicon 2014, 92:186-192.
17. De Genst E., Silence K., Decanniere K., Conrath K., Loris R., Kinne R., Muyldermans S., Wyns L. Molecular basis for the preferential cleft recognition by dromedary heavy-chain antibodies. Proc. Natl. ACA Sci. U. S. A. 2006, 103:4586-4591.
18. Sukhanova A., Even-Desrumeaux K., Kisserli A., Tabary T., Reveil B., Millot J.M., Chames P., Baty D., Artemyev M., Oleinikov V., Pluot M., Cohen J.H.M., Nabiev I. Oriented conjugates of single-domain antibodies and quantum dots: toward a new generation of ultrasmall diagnostic nanoprobes. Nanomed. Nanotechnol. Biol. Med. 2012, 8:516-525.
19. Li H.N., Yan J.R., Ou W.J., Liu H., Liu S.Q., Wan Y.K. Construction of a biotinylated cameloid-like antibody for lable-free detection of apolipoprotein B-100. Biosens. Bioelectron. 2015, 64:111-118.
20. Hamerscasterman C., Atarhouch T., Muyldermans S., Robinson G., Hamers C., Songa E.B., Bendahman N., Hamers R. Naturally-occurring antibodies devoid of light-chains. Nature 1993, 363:446-448.
21. Wang G.L., Yu P.P., Xu J.J., Chen H.Y. A label-free photoelectrochemical immunosensor based on water-soluble CdS quantum dots. J. Phys. Chem. C 2009, 113:11142-11148.
22. 2/CdS hybrid. Biosens. Bioelectron. 2009, 25:791-796.
23. Haddour N., Chauvin J., Gondran C., Cosnier S. Photoelectrochemical immunosensor for label-free detection and quantification of anti-cholera toxin antibody. J. Am. Chem. Soc. 2006, 128:9693-9698.
24. 2 nanotube arrays. Analyst 2013, 138:5726-5733.
25. Wang P., Ma X.Y., Su M.Q., Hao Q., Lei J.P., Ju H.X. Cathode photoelectrochemical sensing of copper(II) based on analyte-induced formation of exciton trapping. Chem. Commun. 2012, 48:10216-10218.
26. Kang Q., Chen Y.F., Li C.C., Cai Q.Y., Yao S.Z., Grimes C.A. A photoelectrochemical immunosensor for benzo[a]pyrene detection amplified by bifunctional gold nanoparticles. Chem. Commun. 2011, 47:12509-12511.
27. Wang J., Shan Y., Zhao W.W., Xu J.J., Chen H.Y. Gold nanoparticle enhanced electrochemiluminescence of CdS thin films for ultrasensitive thrombin detection. Anal. Chem. 2011, 83:4004-4011.
28. Golub E., Niazov A., Freeman R., Zatsepin M., Willner I. Photoelectrochemical biosensors without external irradiation: probing enzyme activities and DNA sensing using hemin/G-quadruplex-stimulated chemiluminescence resonance energy transfer (CRET) generation of photocurrents. J. Phys. Chem. C 2012, 116:13827-13834.
29. Zhou Y.L., Xu Z.N., Wang M., Sun B., Yin H.S., Ai S.Y. DNA methyltransferase activity assay based on visible light-activated photoelectrochemical biosensor. Biosens. Bioelectron. 2014, 53:263-267.
30. 2 nanowire photoelectrochemical biosensors. J. Mater. Chem. A 2014, 2:6153-6157.
31. Schubert K., Khalid W., Yue Z., Parak W.J., Lisdat F. Quantum-dot-modified electrode in combination with NADH-dependent dehydrogenase reactions for substrate analysis. Langmuir 2010, 26:1395-1400.
32. Li H.N., Mu Y.W., Yan J.R., Cui D.M., Ou W.J., Wan Y.K., Liu S.Q. Label-free photoelectrochemical immunosensor for neutrophil gelatinase-associated lipocalin based on the use of nanobodies. Anal. Chem. 2015, 87:2007-2015.
33. Qian J., Zhu W., Mi L., Xu X., Yu J.C., Cui D.M., Xue Y.C., Liu S.Q. Nanohybrids of quantum dots and cytochrome P450 for light-driven drug metabolism. J. Electroanal. Chem. 2014, 733:27-32.
34. Bever C.R.S., Majkova Z., Radhakrishnan R., Suni I., McCoy M., Wang Y.R., Dechant J., Gee S., Hammock B.D. Development and utilization of camelid VHH antibodies from alpaca for 2,2',4,4'-tetrabrominated diphenyl ether detection. Anal. Chem. 2014, 86:7875-7882.
35. 2 nanotube arrays. Anal. Chem. 2014, 86:8003-8009.
36. Muyldermans S. Nanobodies: natural single-domain antibodies. Annu. Rev. Biochem. 2013, 82:775-797.
37. Saerens D., Conrath K., Govaert J., Muyldermans S. Disulfide bond introduction for general stabilization of immunoglobulin heavy-chain variable domains. J. Mol. Biol. 2008, 377:478-488.
38. Hussack G., Hirama T., Ding W., MacKenzie R., Tanha J. Engineered single-domain antibodies with high protease resistance and thermal stability. PLoS One 2011, 6.
39. 2 nanotube structure-based label-free immunosensor. Anal. Chem. 2010, 82:9749-9754.
40. Peng T.Y., Hasegawa A., Qiu J.R., Hirao K. Fabrication of titania tubules with high surface area and well-developed mesostructural walls by surfactant-mediated templating method. Chem. Mater. 2003, 15:2011-2016.
41. 2 nanotube arrays in dye-sensitized solar cells. Nano Lett. 2006, 6:215-218.
42. Tu W.W., Lei J.P., Wang P., Ju H.X. Photoelectrochemistry of free-base-porphyrin-functionalized zinc oxide nanoparticles and their applications in biosensing. Chem. Eur. J. 2011, 17:9440-9447.
43. Grubb A., Lofberg H., Barrett A.J. The disulfide bridges of human cystatin-C (gamma-trace) and chicken cystatin. FEBS Lett. 1984, 170:370-374.
44. Ni J., Abrahamson M., Zhang M., Fernandez M.A., Grubb A., Su J., Yu G.L., Li Y.L., Parmelee D., Xing L., Coleman T.A., Gentz S., Thotakura R., Nguyen N., Hesselberg M., Gentz R. Cystatin E is a novel human cysteine proteinase inhibitor with structural resemblance to family 2 cystatins. J. Biol. Chem. 1997, 272:10853-10858.
45. Ishiguro H., Ohkubo I., Mizokami M., Titani K., Sasaki M. The use of monoclonal-antibodies to define levels of cystatin-C in normal human-serum. Hybridoma 1989, 8:303-313.
46. 2-microglobulin. Clin. Chim. Acta 1983, 128:249-260.