메뉴 건너뛰기




Volumn 374, Issue 5, 2016, Pages 422-433

Assessment of minimal residual disease in standard-risk AML

(22)  Ivey, Adam a   Hills, Robert K e   Simpson, Michael A b   Jovanovic, Jelena V b   Gilkes, Amanda e   Grech, Angela f   Patel, Yashma c   Bhudia, Neesa d   Farah, Hassan b   Mason, Joanne g   Wall, Kerry g   Akiki, Susanna g   Griffiths, Michael g   Solomon, Ellen b   McCaughan, Frank b   Linch, David C c   Gale, Rosemary E c   Vyas, Paresh h   Freeman, Sylvie D i   Russell, Nigel j   more..


Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; NUCLEOPHOSMIN; DNA; NUCLEAR PROTEIN; TRANSCRIPTOME;

EID: 84956917285     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1507471     Document Type: Article
Times cited : (648)

References (40)
  • 1
    • 84885735554 scopus 로고    scopus 로고
    • Mutational landscape and significance across 12 major cancer types
    • Kandoth C, McLellan MD, Vandin F, et al. Mutational landscape and significance across 12 major cancer types. Nature 2013; 502: 333-9.
    • (2013) Nature , vol.502 , pp. 333-339
    • Kandoth, C.1    McLellan, M.D.2    Vandin, F.3
  • 2
    • 84878372012 scopus 로고    scopus 로고
    • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
    • Cancer Genome Atlas Research Network. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. N Engl J Med 2013; 368: 2059-74.
    • (2013) N Engl J Med , vol.368 , pp. 2059-2074
    • Cancer Genome Atlas Research Network1
  • 3
    • 84955451182 scopus 로고    scopus 로고
    • Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevance
    • Grimwade D, Ivey I, Huntly BJP. Molecular landscape of acute myeloid leukemia in younger adults and its clinical relevance. Blood 2016; 127: 29-41.
    • (2016) Blood , vol.127 , pp. 29-41
    • Grimwade, D.1    Ivey, I.2    Bjp, H.3
  • 4
    • 77449159028 scopus 로고    scopus 로고
    • European leukemianet. Diagnosis and management of acute myeloid leukemia in adults: Recommendations from an international expert panel, on behalf of the European LeukemiaNet
    • Döhner H, Estey EH, Amadori S, et al. European LeukemiaNet. Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet. Blood 2010; 115: 453-74.
    • (2010) Blood , vol.115 , pp. 453-474
    • Döhner, H.1    Estey, E.H.2    Amadori, S.3
  • 5
    • 84867099700 scopus 로고    scopus 로고
    • The european leukemianet AML working party consensus statement on allogeneic hsct for patients with AML in remission: An integrated-risk adapted approach
    • Cornelissen JJ, Gratwohl A, Schlenk RF, et al. The European LeukemiaNet AML Working Party consensus statement on allogeneic HSCT for patients with AML in remission: an integrated-risk adapted approach. Nat Rev Clin Oncol 2012; 9: 579-90.
    • (2012) Nat Rev Clin Oncol , vol.9 , pp. 579-590
    • Cornelissen, J.J.1    Gratwohl, A.2    Schlenk, R.F.3
  • 7
    • 19944427850 scopus 로고    scopus 로고
    • Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype
    • Falini B, Mecucci C, Tiacci E, et al. Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. N Engl J Med 2005; 352: 254-66.
    • (2005) N Engl J Med , vol.352 , pp. 254-266
    • Falini, B.1    Mecucci, C.2    Tiacci, E.3
  • 8
    • 42949142189 scopus 로고    scopus 로고
    • Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia
    • Schlenk RF, Döhner K, Krauter J, et al. Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia. N Engl J Med 2008; 358: 1909-18.
    • (2008) N Engl J Med , vol.358 , pp. 1909-1918
    • Schlenk, R.F.1    Döhner, K.2    Krauter, J.3
  • 9
    • 78649906060 scopus 로고    scopus 로고
    • DNMT3A mutations in acute myeloid leukemia
    • Ley TJ, Ding L, Walter MJ, et al. DNMT3A mutations in acute myeloid leukemia. N Engl J Med 2010; 363: 2424-33.
    • (2010) N Engl J Med , vol.363 , pp. 2424-2433
    • Ley, T.J.1    Ding, L.2    Walter, M.J.3
  • 10
    • 84863116398 scopus 로고    scopus 로고
    • Age-related prognostic impact of different types of DNMT3A mutations in adults with primary cytogenetically normal acute myeloid leukemia
    • Marcucci G, Metzeler KH, Schwind S, et al. Age-related prognostic impact of different types of DNMT3A mutations in adults with primary cytogenetically normal acute myeloid leukemia. J Clin Oncol 2012; 30: 742-50.
    • (2012) J Clin Oncol , vol.30 , pp. 742-750
    • Marcucci, G.1    Metzeler, K.H.2    Schwind, S.3
  • 11
    • 84937576519 scopus 로고    scopus 로고
    • Simpson's paradox and the impact of different DNMT3A mutations on outcome in younger adults with acute myeloid leukemia
    • Gale RE, Lamb K, Allen C, et al. Simpson's paradox and the impact of different DNMT3A mutations on outcome in younger adults with acute myeloid leukemia. J Clin Oncol 2015; 33: 2072-83.
    • (2015) J Clin Oncol , vol.33 , pp. 2072-2083
    • Gale, R.E.1    Lamb, K.2    Allen, C.3
  • 12
    • 84929148668 scopus 로고    scopus 로고
    • Impact of additional genetic alterations on the outcome of patients with NPM1-mutated cytogenetically normal acute myeloid leukemia
    • Peterlin P, Renneville A, Ben Abdelali R, et al. Impact of additional genetic alterations on the outcome of patients with NPM1-mutated cytogenetically normal acute myeloid leukemia. Haematologica 2015; 100(5): e196-9.
    • (2015) Haematologica , vol.100 , Issue.5 , pp. e196-e199
    • Peterlin, P.1    Renneville, A.2    Ben Abdelali, R.3
  • 13
    • 84863393263 scopus 로고    scopus 로고
    • Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
    • Patel JP, Gönen M, Figueroa ME, et al. Prognostic relevance of integrated genetic profiling in acute myeloid leukemia. N Engl J Med 2012; 366: 1079-89.
    • (2012) N Engl J Med , vol.366 , pp. 1079-1089
    • Patel, J.P.1    Gönen, M.2    Figueroa, M.E.3
  • 14
    • 84867806184 scopus 로고    scopus 로고
    • A novel hierarchical prognostic model of AML solely based on molecular mutations
    • Grossmann V, Schnittger S, Kohlmann A, et al. A novel hierarchical prognostic model of AML solely based on molecular mutations. Blood 2012; 120: 2963-72.
    • (2012) Blood , vol.120 , pp. 2963-2972
    • Grossmann, V.1    Schnittger, S.2    Kohlmann, A.3
  • 15
    • 84913553522 scopus 로고    scopus 로고
    • Defining minimal residual disease in acute myeloid leukemia: Which platforms are ready for "prime time"?
    • Grimwade D, Freeman SD. Defining minimal residual disease in acute myeloid leukemia: which platforms are ready for "prime time"? Blood 2014; 124: 3345-55.
    • (2014) Blood , vol.124 , pp. 3345-3355
    • Grimwade, D.1    Freeman, S.D.2
  • 16
    • 33744464741 scopus 로고    scopus 로고
    • Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations
    • Gorello P, Cazzaniga G, Alberti F, et al. Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations. Leukemia 2006; 20: 1103-8.
    • (2006) Leukemia , vol.20 , pp. 1103-1108
    • Gorello, P.1    Cazzaniga, G.2    Alberti, F.3
  • 17
    • 34247640052 scopus 로고    scopus 로고
    • Clinical implications of minimal residual disease monitoring by quantitative polymerase chain reaction in acute myeloid leukemia patients bearing nucleophosmin (NPM1) mutations
    • Chou WC, Tang JL, Wu SJ, et al. Clinical implications of minimal residual disease monitoring by quantitative polymerase chain reaction in acute myeloid leukemia patients bearing nucleophosmin (NPM1) mutations. Leukemia 2007; 21: 998-1004.
    • (2007) Leukemia , vol.21 , pp. 998-1004
    • Chou, W.C.1    Tang, J.L.2    Wu, S.J.3
  • 18
    • 70349579540 scopus 로고    scopus 로고
    • Minimal residual disease levels assessed by NPM1 mutation-specific RQ-PCR provide important prognostic information in AML
    • Schnittger S, Kern W, Tschulik C, et al. Minimal residual disease levels assessed by NPM1 mutation-specific RQ-PCR provide important prognostic information in AML. Blood 2009; 114: 2220-31.
    • (2009) Blood , vol.114 , pp. 2220-2231
    • Schnittger, S.1    Kern, W.2    Tschulik, C.3
  • 19
    • 79960127726 scopus 로고    scopus 로고
    • Monitoring of minimal residual disease in npm1-mutated acute myeloid leukemia: A study from the German-austrian acute myeloid leukemia study group
    • Krönke J, Schlenk RF, Jensen KO, et al. Monitoring of minimal residual disease in NPM1-mutated acute myeloid leukemia: a study from the German-Austrian Acute Myeloid Leukemia Study Group. J Clin Oncol 2011; 29: 2709-16.
    • (2011) J Clin Oncol , vol.29 , pp. 2709-2716
    • Krönke, J.1    Schlenk, R.F.2    Jensen, K.O.3
  • 20
    • 84883677161 scopus 로고    scopus 로고
    • The level of residual disease based on mutant NPM1 is an independent prognostic factor for relapse and survival in AML
    • Shayegi N, Kramer M, Bornhäuser M, et al. The level of residual disease based on mutant NPM1 is an independent prognostic factor for relapse and survival in AML. Blood 2013; 122: 83-92.
    • (2013) Blood , vol.122 , pp. 83-92
    • Shayegi, N.1    Kramer, M.2    Bornhäuser, M.3
  • 21
    • 84905169133 scopus 로고    scopus 로고
    • Molecular response assessment by quantitative real-time polymerase chain reaction after induction therapy in NPM1-mutated patients identifies those at high risk of relapse
    • Hubmann M, Köhnke T, Hoster E, et al. Molecular response assessment by quantitative real-time polymerase chain reaction after induction therapy in NPM1-mutated patients identifies those at high risk of relapse. Haematologica 2014; 99: 1317-25.
    • (2014) Haematologica , vol.99 , pp. 1317-1325
    • Hubmann, M.1    Köhnke, T.2    Hoster, E.3
  • 22
    • 84906266071 scopus 로고    scopus 로고
    • MRD assessed by WT1 and NPM1 transcript levels identifies distinct outcomes in AML patients and is influenced by gemtuzumab ozogamicin
    • Lambert J, Lambert J, Nibourel O, et al. MRD assessed by WT1 and NPM1 transcript levels identifies distinct outcomes in AML patients and is influenced by gemtuzumab ozogamicin. Oncotarget 2014; 5: 6280-8.
    • (2014) Oncotarget , vol.5 , pp. 6280-6288
    • Lambert, J.1    Lambert, J.2    Nibourel, O.3
  • 23
    • 84894304555 scopus 로고    scopus 로고
    • Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission
    • Corces-Zimmerman MR, Hong WJ, Weissman IL, Medeiros BC, Majeti R. Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. Proc Natl Acad Sci U S A 2014; 111: 2548-53.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 2548-2553
    • Corces-Zimmerman, M.R.1    Hong, W.J.2    Weissman, I.L.3    Medeiros, B.C.4    Majeti, R.5
  • 24
    • 84894245627 scopus 로고    scopus 로고
    • Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia
    • Shlush LI, Zandi S, Mitchell A, et al. Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia. Nature 2014; 506: 328-33.
    • (2014) Nature , vol.506 , pp. 328-333
    • Shlush, L.I.1    Zandi, S.2    Mitchell, A.3
  • 25
    • 84932615484 scopus 로고    scopus 로고
    • A randomized comparison of daunorubicin 90 mg/m2 vs 60 mg/m2 in AML induction: Results from the UK NCRI AML17 trial in 1206 patients
    • Burnett AK, Russell NH, Hills RK, et al. A randomized comparison of daunorubicin 90 mg/m2 vs 60 mg/m2 in AML induction: results from the UK NCRI AML17 trial in 1206 patients. Blood 2015; 125: 3878-85.
    • (2015) Blood , vol.125 , pp. 3878-3885
    • Burnett, A.K.1    Russell, N.H.2    Hills, R.K.3
  • 27
    • 84874729279 scopus 로고    scopus 로고
    • Utility of a clinical risk score to identify high-risk patients with de novo acute myeloid leukaemia in first remission after high-dose cytarabine (HiDAC) based induction chemotherapy
    • Ling V, Burnett AK, Bradstock K, Seymour JF, Hills RK, Wei A. Utility of a clinical risk score to identify high-risk patients with de novo acute myeloid leukaemia in first remission after high-dose cytarabine (HiDAC) based induction chemotherapy. Br J Haematol 2013; 160: 861-3.
    • (2013) Br J Haematol , vol.160 , pp. 861-863
    • Ling, V.1    Burnett, A.K.2    Bradstock, K.3    Seymour, J.F.4    Hills, R.K.5    Wei, A.6
  • 28
    • 84921754720 scopus 로고    scopus 로고
    • The prognostic relevance of flt3 and npm1 mutations on older patients treated intensively or nonintensively: A study of 1312 patients in the UK NCRI AML16 trial
    • Lazenby M, Gilkes AF, Marrin C, Evans A, Hills RK, Burnett AK. The prognostic relevance of flt3 and npm1 mutations on older patients treated intensively or nonintensively: a study of 1312 patients in the UK NCRI AML16 trial. Leukemia 2014; 28: 1953-9.
    • (2014) Leukemia , vol.28 , pp. 1953-1959
    • Lazenby, M.1    Gilkes, A.F.2    Marrin, C.3    Evans, A.4    Hills, R.K.5    Burnett, A.K.6
  • 29
    • 68949137224 scopus 로고    scopus 로고
    • Prospective minimal residual disease monitoring to predict relapse of acute promyelocytic leukemia and to direct preemptive arsenic trioxide therapy
    • Grimwade D, Jovanovic JV, Hills RK, et al. Prospective minimal residual disease monitoring to predict relapse of acute promyelocytic leukemia and to direct preemptive arsenic trioxide therapy. J Clin Oncol 2009; 27: 3650-8.
    • (2009) J Clin Oncol , vol.27 , pp. 3650-3658
    • Grimwade, D.1    Jovanovic, J.V.2    Hills, R.K.3
  • 30
    • 9144222001 scopus 로고    scopus 로고
    • Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - A Europe against cancer program
    • Gabert J, Beillard E, van der Velden VH, et al. Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia-a Europe Against Cancer program. Leukemia 2003; 17: 2318-57.
    • (2003) Leukemia , vol.17 , pp. 2318-2357
    • Gabert, J.1    Beillard, E.2    Van Der Velden, V.H.3
  • 31
    • 84929166801 scopus 로고    scopus 로고
    • Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia
    • Kühnl A, Valk PJ, Sanders MA, et al. Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia. Blood 2015; 125: 2985-94.
    • (2015) Blood , vol.125 , pp. 2985-2994
    • Kühnl, A.1    Valk, P.J.2    Sanders, M.A.3
  • 32
    • 84904124365 scopus 로고    scopus 로고
    • Impact of FLT3 ITD mutant allele level on relapse risk in intermediate-risk acute myeloid leukemia
    • Linch DC, Hills RK, Burnett AK, Khwaja A, Gale RE. Impact of FLT3 ITD mutant allele level on relapse risk in intermediate-risk acute myeloid leukemia. Blood 2014; 124: 273-6.
    • (2014) Blood , vol.124 , pp. 273-276
    • Linch, D.C.1    Hills, R.K.2    Burnett, A.K.3    Khwaja, A.4    Gale, R.E.5
  • 33
    • 1542753559 scopus 로고    scopus 로고
    • Revised recommendations of the international working group for diagnosis, standardization of response criteria, treatment outcomes, and reporting standards for therapeutic trials in acute myeloid leukemia
    • Cheson BD, Bennett JM, Kopecky KJ, et al. Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia. J Clin Oncol 2003; 21: 4642-9.
    • (2003) J Clin Oncol , vol.21 , pp. 4642-4649
    • Cheson, B.D.1    Bennett, J.M.2    Kopecky, K.J.3
  • 34
    • 50949113696 scopus 로고    scopus 로고
    • Segmental uniparental disomy is a commonly acquired genetic event in relapsed acute myeloid leukemia
    • Raghavan M, Smith LL, Lillington DM, et al. Segmental uniparental disomy is a commonly acquired genetic event in relapsed acute myeloid leukemia. Blood 2008; 112: 814-21.
    • (2008) Blood , vol.112 , pp. 814-821
    • Raghavan, M.1    Smith, L.L.2    Lillington, D.M.3
  • 35
    • 77955914238 scopus 로고    scopus 로고
    • Refinement of cytogenetic classification in acute myeloid leukemia: Determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials
    • Grimwade D, Hills RK, Moorman AV, et al. Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials. Blood 2010; 116: 354-65.
    • (2010) Blood , vol.116 , pp. 354-365
    • Grimwade, D.1    Hills, R.K.2    Moorman, A.V.3
  • 36
    • 84921779422 scopus 로고    scopus 로고
    • Should persons with acute myeloid leukemia have a transplant in first remission?
    • Gale RP, Wiernik PH, Lazarus HM. Should persons with acute myeloid leukemia have a transplant in first remission? Leukemia 2014; 28: 1949-52.
    • (2014) Leukemia , vol.28 , pp. 1949-1952
    • Gale, R.P.1    Wiernik, P.H.2    Lazarus, H.M.3
  • 37
    • 61949441174 scopus 로고    scopus 로고
    • Management of acute promyelocytic leukemia: Recommendations from an expert panel on behalf of the european leukemianet
    • Sanz MA, Grimwade D, Tallman MS, et al. Management of acute promyelocytic leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet. Blood 2009; 113: 1875-91.
    • (2009) Blood , vol.113 , pp. 1875-1891
    • Sanz, M.A.1    Grimwade, D.2    Tallman, M.S.3
  • 38
    • 84937408512 scopus 로고    scopus 로고
    • Detection and management of minimal residual disease in acute lymphoblastic leukemia
    • Schrappe M. Detection and management of minimal residual disease in acute lymphoblastic leukemia. Hematology Am Soc Hematol Educ Program 2014; 2014: 244-9.
    • (2014) Hematology Am Soc Hematol Educ Program , vol.2014 , pp. 244-249
    • Schrappe, M.1
  • 39
    • 84883730914 scopus 로고    scopus 로고
    • Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia
    • Krönke J, Bullinger L, Teleanu V, et al. Clonal evolution in relapsed NPM1-mutated acute myeloid leukemia. Blood 2013; 122: 100-8.
    • (2013) Blood , vol.122 , pp. 100-108
    • Krönke, J.1    Bullinger, L.2    Teleanu, V.3
  • 40
    • 84916229685 scopus 로고    scopus 로고
    • Persistence of DNMT3A mutations at long-term remission in adult patients with AML
    • Pløen GG, Nederby L, Guldberg P, et al. Persistence of DNMT3A mutations at long-term remission in adult patients with AML. Br J Haematol 2014; 167: 478-86.
    • (2014) Br J Haematol , vol.167 , pp. 478-486
    • Pløen, G.G.1    Nederby, L.2    Guldberg, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.