Curcumin ameliorates dopaminergic neuronal oxidative damage via activation of the Akt/Nrf2 pathway

Molecular Medicine Reports

Volumn 13, Issue 2, 2016, Pages 1381-1388

  Cui, Qunli ^a   Li, Xin ^a   Zhu, Hongcan ^b  

^a ZHENGZHOU UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

Author keywords

Curcumin; Dopaminergic neurons; Oxidative damage; Parkinson's disease; Rotenone

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CURCUMA LONGA EXTRACT; CURCUMIN; GLUTATHIONE; HEME OXYGENASE 1; LENTIVIRUS VECTOR; MALONALDEHYDE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); ROTENONE; SHORT HAIRPIN RNA; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANSCRIPTION FACTOR NRF2; TYROSINE 3 MONOOXYGENASE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; ANTIOXIDANT; CHROMONE DERIVATIVE; MORPHOLINE DERIVATIVE; NEUROPROTECTIVE AGENT; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOCHEMICAL ANALYSIS; CATALEPSY; CIRCLING BEHAVIOR; CONTROLLED STUDY; CURCUMA LONGA; DOPAMINERGIC NERVE CELL; DRUG EFFECT; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MOTOR DYSFUNCTION; NERVE CELL LESION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OPEN FIELD TEST; OXIDATIVE STRESS; PARKINSON DISEASE; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; ANIMAL; DRUG EFFECTS; HEK293 CELL LINE; LEWIS RAT; METABOLISM; PATHOLOGY;

ANIMALS; ANTIOXIDANTS; CHROMONES; CURCUMIN; DOPAMINERGIC NEURONS; GLUTATHIONE; HEK293 CELLS; HUMANS; MALE; MALONDIALDEHYDE; MORPHOLINES; NEUROPROTECTION; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PARKINSON DISEASE; PROTO-ONCOGENE PROTEINS C-AKT; RATS, INBRED LEW; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; ROTENONE;

EID: 84956881839     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4657     Document Type: Article

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