Hydroxylation of Longiborneol by a Clm2-Encoded CYP450 Monooxygenase to Produce Culmorin in Fusarium graminearum

Journal of Natural Products

Volumn 79, Issue 1, 2016, Pages 81-88

  Bahadoor, Adilah ^a   Schneiderman, Danielle ^a   Gemmill, Larissa ^a   Bosnich, Whynn ^a   Blackwell, Barbara ^a   Melanson, Jeremy E ^b   McRae, Garnet ^b   Harris, Linda J ^a  

^a OTTAWA RESEARCH AND DEVELOPMENT CENTRE   (Canada)

^b NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

11 EPI ACETYLCULMORIN; 12 HYDROXYLONGIBORNEOL; 15 HYDROXYLONGIBORNEOL; 3 HYDROXYLONGIBORNEOL; 5 HYDROXYLONGIBORNEOL; CULMORIN; CYTOCHROME P450; PROTEIN; PROTEIN CLM2; SESQUITERPENE DERIVATIVE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE; LONGIBORNEOL; SESQUITERPENE;

ARTICLE; CONTROLLED STUDY; FUSARIUM GRAMINEARUM; GENE EXPRESSION; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROXYLATION; LIGHT SCATTERING; LIQUID CULTURE; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; X RAY CRYSTALLOGRAPHY; CHEMICAL STRUCTURE; CONFORMATION; ENZYMOLOGY; FUSARIUM; GENETICS; METABOLISM; NUCLEAR MAGNETIC RESONANCE; STEREOISOMERISM;

CRYSTALLOGRAPHY, X-RAY; CYTOCHROME P-450 ENZYME SYSTEM; FUSARIUM; HYDROXYLATION; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; SESQUITERPENES; STEREOISOMERISM;

EID: 84956847507     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/acs.jnatprod.5b00676     Document Type: Article

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