메뉴 건너뛰기




Volumn 56, Issue 2, 2016, Pages 170-175

Folic acid supplementation for pregnant women and those planning pregnancy: 2015 update

Author keywords

folate; folic acid; genetics of neural tube defects; neural tube defects; prevention; spina bifida

Indexed keywords

FOLIC ACID; VITAMIN;

EID: 84956756059     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1002/jcph.616     Document Type: Review
Times cited : (71)

References (44)
  • 1
    • 0025863475 scopus 로고
    • Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study
    • MRC Vitamin Study Research Group.
    • MRC Vitamin Study Research Group. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet. 1991; 338 (8760): 131-137.
    • (1991) Lancet , vol.338 , Issue.8760 , pp. 131-137
  • 2
    • 0027080461 scopus 로고
    • Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation
    • Czeizel AE, Dudás I,. Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation. N Engl J Med. 1992; 327 (26): 1832-1835.
    • (1992) N Engl J Med , vol.327 , Issue.26 , pp. 1832-1835
    • Czeizel, A.E.1    Dudás, I.2
  • 3
    • 0032728921 scopus 로고    scopus 로고
    • Achieving a public health recommendation for preventing neural tube defects with folic acid
    • Werler MM, Louik C, Mitchell AA,. Achieving a public health recommendation for preventing neural tube defects with folic acid. Am J Public Health. 1999; 89 (11): 1637-1640.
    • (1999) Am J Public Health , vol.89 , Issue.11 , pp. 1637-1640
    • Werler, M.M.1    Louik, C.2    Mitchell, A.A.3
  • 4
    • 84922447495 scopus 로고    scopus 로고
    • Updated estimates of neural tube defects prevented by mandatory folic acid fortification - United States, 1995-2011
    • Williams J, Mai CT, Mulinare J, et al., Updated estimates of neural tube defects prevented by mandatory folic acid fortification-United States, 1995-2011. MMWR Morbid Mortal Wkly Rep. 2015; 64 (1): 1-5.
    • (2015) MMWR Morbid Mortal Wkly Rep , vol.64 , Issue.1 , pp. 1-5
    • Williams, J.1    Mai, C.T.2    Mulinare, J.3
  • 5
    • 0028863219 scopus 로고
    • Folate levels and neural tube defects. Implications for prevention
    • Daly LE, Kirke PN, Molloy A, Weir DG, Scott JM,. Folate levels and neural tube defects. Implications for prevention. JAMA 1995; 274 (21): 1698-1702.
    • (1995) JAMA , vol.274 , Issue.21 , pp. 1698-1702
    • Daly, L.E.1    Kirke, P.N.2    Molloy, A.3    Weir, D.G.4    Scott, J.M.5
  • 6
    • 84904876075 scopus 로고    scopus 로고
    • Population red blood cell folate concentrations for prevention of neural tube defects: Bayesian model
    • Crider KS, Devine O, Hao L, et al., Population red blood cell folate concentrations for prevention of neural tube defects: Bayesian model. BMJ 2014; 349: g4554. doi: 10.1136/bmj.g4554
    • (2014) BMJ , vol.349 , pp. g4554
    • Crider, K.S.1    Devine, O.2    Hao, L.3
  • 7
    • 0035894581 scopus 로고    scopus 로고
    • Quantifying the effect of folic acid
    • Wald NJ, Law MR, Morris JK, Wald DS., Quantifying the effect of folic acid. Lancet. 2001; 358 (9298): 2069-2073.
    • (2001) Lancet , vol.358 , Issue.9298 , pp. 2069-2073
    • Wald, N.J.1    Law, M.R.2    Morris, J.K.3    Wald, D.S.4
  • 8
    • 47249084202 scopus 로고    scopus 로고
    • Folate fortification and supplementation - are we there yet
    • Bar-Oz B, Koren G, Nguyen P, Kapur BM., Folate fortification and supplementation-are we there yet ? Reprod Toxicol. 2008; 25 (4): 408-412.
    • (2008) Reprod Toxicol , vol.25 , Issue.4 , pp. 408-412
    • Bar-Oz, B.1    Koren, G.2    Nguyen, P.3    Kapur, B.M.4
  • 9
    • 84866274971 scopus 로고    scopus 로고
    • Differences in erythrocyte folate concentrations in older adults reached steady-state within one year in a two-year, controlled, 1 mg/d folate supplementation trial
    • Bradbury KE, Williams SM, Green TJ, et al., Differences in erythrocyte folate concentrations in older adults reached steady-state within one year in a two-year, controlled, 1 mg/d folate supplementation trial. J Nutr. 2012; 142 (9): 1633-1637.
    • (2012) J Nutr , vol.142 , Issue.9 , pp. 1633-1637
    • Bradbury, K.E.1    Williams, S.M.2    Green, T.J.3
  • 10
    • 74049089339 scopus 로고    scopus 로고
    • Folic acid source, usual intake, and folate and Vitamin B-12 status in US adults: National Health and Nutrition Examination Survey (NHANES) 2003-2006
    • Yang Q, Cogswell ME, Hamner HC, et al., Folic acid source, usual intake, and folate and vitamin B-12 status in US adults: National Health and Nutrition Examination Survey (NHANES) 2003-2006. Am J Clin Nutr. 2010; 91 (1): 64-72.
    • (2010) Am J Clin Nutr , vol.91 , Issue.1 , pp. 64-72
    • Yang, Q.1    Cogswell, M.E.2    Hamner, H.C.3
  • 11
    • 58149352931 scopus 로고    scopus 로고
    • Comparing folic acid pharmacokinetics among women of childbearing age: Single dose ingestion of 1.1 versus 5 mg folic acid
    • Nguyen P, Boskovic R, Yazdani P, Kapur B, Vandenberghe H, Koren G., Comparing folic acid pharmacokinetics among women of childbearing age: single dose ingestion of 1.1 versus 5 mg folic acid. Can J Clin Pharmacol. 2008; 15 (2): e314-e322.
    • (2008) Can J Clin Pharmacol , vol.15 , Issue.2 , pp. e314-e322
    • Nguyen, P.1    Boskovic, R.2    Yazdani, P.3    Kapur, B.4    Vandenberghe, H.5    Koren, G.6
  • 12
    • 6444233166 scopus 로고    scopus 로고
    • Celiac disease during pregnancy
    • Hancock R, Koren G., Celiac disease during pregnancy. Can Fam Physician. 2004; 50: 1361-1363.
    • (2004) Can Fam Physician , vol.50 , pp. 1361-1363
    • Hancock, R.1    Koren, G.2
  • 13
    • 67049087956 scopus 로고    scopus 로고
    • Predictors of prenatal multivitamin adherence in pregnant women
    • Nguyen P, Thomas M, Koren G., Predictors of prenatal multivitamin adherence in pregnant women. J Clin Pharmacol. 2009; 49 (6): 735-742.
    • (2009) J Clin Pharmacol , vol.49 , Issue.6 , pp. 735-742
    • Nguyen, P.1    Thomas, M.2    Koren, G.3
  • 14
    • 48249129119 scopus 로고    scopus 로고
    • Conclusions of a WHO Technical Consultation on folate and vitamin B12 deficiencies
    • de Benoist B., Conclusions of a WHO Technical Consultation on folate and vitamin B12 deficiencies. Food Nutr Bull. 2008; 29 (2 Suppl): S238-S244.
    • (2008) Food Nutr Bull , vol.29 , pp. S238-S244
    • De Benoist, B.1
  • 15
    • 84939432971 scopus 로고    scopus 로고
    • Association between folate status and use of oral contraceptives: A systematic review and meta-analysis
    • Shere M, Bapat P, NickeL C, Kapur B, Koren G., Association between folate status and use of oral contraceptives: a systematic review and meta-analysis. J Obstet Gynaecol Can. 2015; 37 (5): 430-438.
    • (2015) J Obstet Gynaecol Can , vol.37 , Issue.5 , pp. 430-438
    • Shere, M.1    Bapat, P.2    NickeL, C.3    Kapur, B.4    Koren, G.5
  • 17
    • 79956330532 scopus 로고    scopus 로고
    • MTHFR 677C→T genotype is associated with folate and homocysteine concentrations in a large, population-based, double-blind trial of folic acid supplementation
    • Crider KS, Zhu JH, Hao L, et al., MTHFR 677C→T genotype is associated with folate and homocysteine concentrations in a large, population-based, double-blind trial of folic acid supplementation. Am J Clin Nutr. 2011; 93 (6): 1365-1372.
    • (2011) Am J Clin Nutr , vol.93 , Issue.6 , pp. 1365-1372
    • Crider, K.S.1    Zhu, J.H.2    Hao, L.3
  • 18
    • 0347988053 scopus 로고    scopus 로고
    • Autoantibodies against folate receptors in women with a pregnancy complicated by a neural-tube defect
    • Rothenberg SP, da Costa MP, Sequeira JM, et al., Autoantibodies against folate receptors in women with a pregnancy complicated by a neural-tube defect. N Engl J Med. 2004; 350 (2): 134-142.
    • (2004) N Engl J Med , vol.350 , Issue.2 , pp. 134-142
    • Rothenberg, S.P.1    Da Costa, M.P.2    Sequeira, J.M.3
  • 19
    • 69049101171 scopus 로고    scopus 로고
    • Association of reduced folate carrier gene polymorphism and maternal folic acid use with neural tube defects
    • Pei L, Liu J, Zhang Y, Zhu H, Ren A., Association of reduced folate carrier gene polymorphism and maternal folic acid use with neural tube defects. Am J Med Genet B Neuropsychiatr Genet. 2009; 150B (6): 874-878.
    • (2009) Am J Med Genet B Neuropsychiatr Genet , vol.150 B , Issue.6 , pp. 874-878
    • Pei, L.1    Liu, J.2    Zhang, Y.3    Zhu, H.4    Ren, A.5
  • 21
    • 0242669376 scopus 로고    scopus 로고
    • Reduced folate carrier polymorphism (80A→G) and neural tube defects
    • De Marco P, Calevo MG, Moroni A, et al., Reduced folate carrier polymorphism (80A→G) and neural tube defects. Eur J Hum Genet. 2003; 11 (3): 245-252.
    • (2003) Eur J Hum Genet , vol.11 , Issue.3 , pp. 245-252
    • De Marco, P.1    Calevo, M.G.2    Moroni, A.3
  • 22
    • 0037083014 scopus 로고    scopus 로고
    • Maternal periconceptional vitamin use, genetic variation of infant reduced folate carrier (A80G), and risk of spina bifida
    • Shaw GM, Lammer EJ, Zhu H, Baker MW, Neri E, Finnell RH., Maternal periconceptional vitamin use, genetic variation of infant reduced folate carrier (A80G), and risk of spina bifida. Am J Med Genet. 2002; 108 (1): 1-6.
    • (2002) Am J Med Genet , vol.108 , Issue.1 , pp. 1-6
    • Shaw, G.M.1    Lammer, E.J.2    Zhu, H.3    Baker, M.W.4    Neri, E.5    Finnell, R.H.6
  • 23
    • 31544464705 scopus 로고    scopus 로고
    • Evaluation of a methylenetetrahydrofolate-dehydrogenase 1958G> A polymorphism for neural tube defect risk
    • De Marco P, Merello E, Calevo MG, et al., Evaluation of a methylenetetrahydrofolate-dehydrogenase 1958G> A polymorphism for neural tube defect risk. J Hum Genet. 2006; 51 (2): 98-103.
    • (2006) J Hum Genet , vol.51 , Issue.2 , pp. 98-103
    • De Marco, P.1    Merello, E.2    Calevo, M.G.3
  • 24
    • 0942290719 scopus 로고    scopus 로고
    • New 19 bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): A risk factor for spina bifida acting in mothers during pregnancy
    • Johnson WG, Stenroos ES, Spychala JR, et al., New 19 bp deletion polymorphism in intron-1 of dihydrofolate reductase (DHFR): a risk factor for spina bifida acting in mothers during pregnancy ? Am J Med Genet A. 2004; 124A (4): 339-345.
    • (2004) Am J Med Genet A , vol.124 A , Issue.4 , pp. 339-345
    • Johnson, W.G.1    Stenroos, E.S.2    Spychala, J.R.3
  • 25
    • 0034190659 scopus 로고    scopus 로고
    • 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: A HuGE review
    • Botto LD, Yang Q,. 5,10-Methylenetetrahydrofolate reductase gene variants and congenital anomalies: a HuGE review. Am J Epidemiol. 2000; 151 (9): 862-877.
    • (2000) Am J Epidemiol , vol.151 , Issue.9 , pp. 862-877
    • Botto, L.D.1    Yang, Q.2
  • 26
    • 0035987006 scopus 로고    scopus 로고
    • Study of MTHFR and MS polymorphisms as risk factors for NTD in the Italian population
    • De Marco P, Calevo MG, Moroni A, et al., Study of MTHFR and MS polymorphisms as risk factors for NTD in the Italian population. J Hum Genet. 2002; 47 (6): 319-324.
    • (2002) J Hum Genet , vol.47 , Issue.6 , pp. 319-324
    • De Marco, P.1    Calevo, M.G.2    Moroni, A.3
  • 28
    • 70849105140 scopus 로고    scopus 로고
    • Exposure to folic acid antagonists during the first trimester of pregnancy and the risk of major malformations
    • Matok I, Gorodischer R, Koren G, Landau D, Wiznitzer A, Levy A., Exposure to folic acid antagonists during the first trimester of pregnancy and the risk of major malformations. Br J Clin Pharmacol. 2009; 68 (6): 956-961.
    • (2009) Br J Clin Pharmacol , vol.68 , Issue.6 , pp. 956-961
    • Matok, I.1    Gorodischer, R.2    Koren, G.3    Landau, D.4    Wiznitzer, A.5    Levy, A.6
  • 29
    • 54849424321 scopus 로고    scopus 로고
    • Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency
    • Roy M, Leclerc D, Wu Q, Gupta S, Kruger WD, Rozen R., Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency. J Cell Biochem. 2008; 105 (2): 467-476.
    • (2008) J Cell Biochem , vol.105 , Issue.2 , pp. 467-476
    • Roy, M.1    Leclerc, D.2    Wu, Q.3    Gupta, S.4    Kruger, W.D.5    Rozen, R.6
  • 30
    • 84859838414 scopus 로고    scopus 로고
    • Simultaneous folate intake may prevent adverse effect of valproic acid on neurulating nervous system
    • Umur AS, Selcuki M, Bursali A, et al., Simultaneous folate intake may prevent adverse effect of valproic acid on neurulating nervous system. Childs Nerv Syst. 2012; 28 (5): 729-737.
    • (2012) Childs Nerv Syst , vol.28 , Issue.5 , pp. 729-737
    • Umur, A.S.1    Selcuki, M.2    Bursali, A.3
  • 31
    • 79958781995 scopus 로고    scopus 로고
    • Dose-dependent risk of malformations with antiepileptic drugs: An analysis of data from the EURAP epilepsy and pregnancy registry
    • Tomson T, Battino D, Bonizzoni E, et al., Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry. Lancet Neurol. 2011; 10 (7): 609-617.
    • (2011) Lancet Neurol , vol.10 , Issue.7 , pp. 609-617
    • Tomson, T.1    Battino, D.2    Bonizzoni, E.3
  • 32
    • 84875612498 scopus 로고    scopus 로고
    • Maternal overweight and obesity and the risk of neural tube defects: A case-control study in China
    • Gao LJ, Wang ZP, Lu QB, Gong R, Sun XH, Zhao ZT., Maternal overweight and obesity and the risk of neural tube defects: a case-control study in China. Birth Defects Res A Clin Mol Teratol. 2013; 97 (3): 161-165.
    • (2013) Birth Defects Res A Clin Mol Teratol , vol.97 , Issue.3 , pp. 161-165
    • Gao, L.J.1    Wang, Z.P.2    Lu, Q.B.3    Gong, R.4    Sun, X.H.5    Zhao, Z.T.6
  • 33
    • 84896713349 scopus 로고    scopus 로고
    • Maternal passive smoking during pregnancy and neural tube defects in offspring: A meta-analysis
    • Wang M, Wang ZP, Zhang M, Zhao ZT., Maternal passive smoking during pregnancy and neural tube defects in offspring: a meta-analysis. Arch Gynecol Obstet. 2014; 289 (3): 513-521.
    • (2014) Arch Gynecol Obstet , vol.289 , Issue.3 , pp. 513-521
    • Wang, M.1    Wang, Z.P.2    Zhang, M.3    Zhao, Z.T.4
  • 34
    • 84883173680 scopus 로고    scopus 로고
    • The impact of folic acid intake on the association among diabetes mellitus, obesity, and spina bifida
    • Parker SE, Yazdy MM, Tinker SC, Mitchell AA, Werler MM., The impact of folic acid intake on the association among diabetes mellitus, obesity, and spina bifida. Am J Obstet Gynecol. 2013; 209 (3): 239.e1-8.
    • (2013) Am J Obstet Gynecol , vol.209 , Issue.3 , pp. 239e1-248e1
    • Parker, S.E.1    Yazdy, M.M.2    Tinker, S.C.3    Mitchell, A.A.4    Werler, M.M.5
  • 35
    • 84909578317 scopus 로고    scopus 로고
    • Infancia y Medio Ambiente (INMA) Project. Folic acid supplements during pregnancy and child psychomotor development after the first year of life
    • Valera-Gran D, García de la Hera M, Navarrete-Muñoz EM,. Infancia y Medio Ambiente (INMA) Project. Folic acid supplements during pregnancy and child psychomotor development after the first year of life. JAMA Pediatr. 2014; 168 (11): e142611. doi: 10.1001/jamapediatrics.2014.2611.
    • (2014) JAMA Pediatr , vol.168 , Issue.11 , pp. e142611
    • Valera-Gran, D.1    García De La Hera, M.2    Navarrete-Muñoz, E.M.3
  • 36
    • 79951550718 scopus 로고    scopus 로고
    • Folate intake and the risk of colorectal cancer: A systematic review and meta-analysis
    • Kennedy DA, Stern SJ, Moretti M., Folate intake and the risk of colorectal cancer: a systematic review and meta-analysis. Cancer Epidemiol. 2011; 35 (1): 2-10.
    • (2011) Cancer Epidemiol , vol.35 , Issue.1 , pp. 2-10
    • Kennedy, D.A.1    Stern, S.J.2    Moretti, M.3
  • 37
    • 78449304532 scopus 로고    scopus 로고
    • Pooled analyses of 13 prospective cohort studies on folate intake and colon cancer
    • Kim DH, Smith-Warner SA, Spiegelman D, et al., Pooled analyses of 13 prospective cohort studies on folate intake and colon cancer. Cancer Causes Control. 2010; 21 (11): 1919-1930.
    • (2010) Cancer Causes Control , vol.21 , Issue.11 , pp. 1919-1930
    • Kim, D.H.1    Smith-Warner, S.A.2    Spiegelman, D.3
  • 38
    • 78751684848 scopus 로고    scopus 로고
    • Folic acid supplementation and colorectal cancer risk: A meta-analysis
    • Fife J, Raniga S, Hider PN, Frizelle FA., Folic acid supplementation and colorectal cancer risk: a meta-analysis. Colorectal Dis. 2011; 13 (2): 132-137.
    • (2011) Colorectal Dis , vol.13 , Issue.2 , pp. 132-137
    • Fife, J.1    Raniga, S.2    Hider, P.N.3    Frizelle, F.A.4
  • 39
    • 84920987678 scopus 로고    scopus 로고
    • Pregnancy-induced changes in the long-term pharmacokinetics of 1.1 mg vs. 5 mg folic acid: A randomized clinical trial
    • Shere M, Nguyen P, Tam C, et al., Pregnancy-induced changes in the long-term pharmacokinetics of 1.1 mg vs. 5 mg folic acid: a randomized clinical trial. J Clin Pharmacol. 2014. doi: 10.1002/jcph.387.
    • (2014) J Clin Pharmacol
    • Shere, M.1    Nguyen, P.2    Tam, C.3
  • 40
    • 61449184554 scopus 로고    scopus 로고
    • Steady state folate concentrations achieved with 5 mg compared with 1.1 mg folic acid supplementation among women of childbearing age
    • Nguyen P, Tam C, O'Connor DL, Kapur B, Koren G., Steady state folate concentrations achieved with 5 mg compared with 1.1 mg folic acid supplementation among women of childbearing age. Am J Clin Nutr. 2009; 89: 844-852.
    • (2009) Am J Clin Nutr , vol.89 , pp. 844-852
    • Nguyen, P.1    Tam, C.2    O'Connor, D.L.3    Kapur, B.4    Koren, G.5
  • 42
    • 84912042064 scopus 로고    scopus 로고
    • High dose of maternal folic acid supplementation is associated to infant asthma
    • Yang L, Jiang L, Bi M, et al., High dose of maternal folic acid supplementation is associated to infant asthma. Food Chem Toxicol. 2015; 75: 88-93.
    • (2015) Food Chem Toxicol , vol.75 , pp. 88-93
    • Yang, L.1    Jiang, L.2    Bi, M.3
  • 43
    • 84911806861 scopus 로고    scopus 로고
    • Maternal high-dose folic acid during pregnancy and asthma medication in the offspring
    • Zetstra-van der Woude PA, De Walle HE, Hoek A, et al., Maternal high-dose folic acid during pregnancy and asthma medication in the offspring. Pharmacoepidemiol Drug Saf. 2014; 23 (10): 1059-1065.
    • (2014) Pharmacoepidemiol Drug Saf , vol.23 , Issue.10 , pp. 1059-1065
    • Zetstra-Van Der Woude, P.A.1    De Walle, H.E.2    Hoek, A.3
  • 44
    • 84916899145 scopus 로고    scopus 로고
    • FIGO Working Group on Best Practice in Maternal-Fetal Medicine. Best practices in maternal fetal medicine
    • FIGO Working Group on Best Practice in Maternal-Fetal Medicine. Best practices in maternal fetal medicine. Int J Gynecol Obstet. 2015; 128: 80-82.
    • (2015) Int J Gynecol Obstet , vol.128 , pp. 80-82


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.