Exposure to folic acid antagonists during the first trimester of pregnancy and the risk of major malformations

British Journal of Clinical Pharmacology

Volumn 68, Issue 6, 2009, Pages 956-962

  Matok, Ilan ^a   Gorodischer, Rafael ^a,b,c,e   Koren, Gideon ^d,e   Landau, Daniella ^a,b,c   Wiznitzer, Arnon ^a,b   Levy, Amalia ^a,e  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^c CLALIT HEALTH SERVICES   (Israel)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

^e BeMORE Collaboration (Ben Gurion Motherisk Obstetric Registry of Exposure Collaboration)   (Israel)

Author keywords

Congenital malformations; Drug safety; Folic acid antagonists; Pregnancy outcomes

Indexed keywords

CARBAMAZEPINE; COLESTYRAMINE; COTRIMOXAZOLE; DIHYDROFOLATE REDUCTASE INHIBITOR; FOLIC ACID ANTAGONIST; LAMOTRIGINE; METHOTREXATE; PHENOBARBITAL; PHENYTOIN; PRIMIDONE; SALAZOSULFAPYRIDINE; VALPROIC ACID; VIGABATRIN;

ADULT; ARTICLE; CARDIOVASCULAR MALFORMATION; CONGENITAL MALFORMATION; CONTROLLED STUDY; DRUG SAFETY; FEMALE; FETUS; FIRST TRIMESTER PREGNANCY; HUMAN; INFANT; ISRAEL; MAJOR CLINICAL STUDY; NEURAL TUBE DEFECT; PREGNANCY OUTCOME; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; THERAPEUTIC ABORTION; URINARY TRACT MALFORMATION;

ABNORMALITIES, DRUG-INDUCED; ADOLESCENT; ADULT; COHORT STUDIES; DATABASES AS TOPIC; FEMALE; FOLIC ACID ANTAGONISTS; HUMANS; INFANT, NEWBORN; ISRAEL; MIDDLE AGED; PREGNANCY; PREGNANCY OUTCOME; PREGNANCY TRIMESTER, FIRST; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES; RISK FACTORS; YOUNG ADULT;

EID: 70849105140     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2009.03544.x     Document Type: Article

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