p53 deficiency linked to B cell translocation gene 2 (BTG2) loss enhances metastatic potential by promoting tumor growth in primary and metastatic sites in patient-derived xenograft (PDX) models of triple-negative breast cancer

Breast Cancer Research

Volumn 18, Issue 1, 2016, Pages

  Powell, Emily ^a   Shao, Jiansu ^a   Yuan, Yuan ^a   Chen, Hsiang Chun ^a   Cai, Shirong ^a   Echeverria, Gloria V ^a   Mistry, Nipun ^a   Decker, Keith F ^b   Schlosberg, Christopher ^b   Do, Kim Anh ^a   Edwards, John R ^b   Liang, Han ^a   Piwnica Worms, David ^a   Piwnica Worms, Helen ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

BTG2; Metastasis; P53; PDX models; Triple negative breast cancer

Indexed keywords

B CELL TRANSLOCATION GENE 2 PROTEIN; PROTEIN P53; TUMOR PROTEIN; UNCLASSIFIED DRUG; BTG2 PROTEIN, HUMAN; IMMEDIATE EARLY PROTEIN; TP53 PROTEIN, HUMAN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B CELL TRANSLOCATION GENE 2 GENE; BIOLUMINESCENCE; CANCER GROWTH; CANCER STAGING; CIRCULATING TUMOR CELL; CONTROLLED STUDY; DISEASE ACTIVITY; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; IN VIVO STUDY; LONGITUDINAL STUDY; METASTASIS; METASTASIS POTENTIAL; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; ONCOGENE; PROTEIN DETERMINATION; PROTEIN FUNCTION; RNA SEQUENCE; TRIPLE NEGATIVE BREAST CANCER; TUMOR SUPPRESSOR GENE; TUMOR VOLUME; TUMOR XENOGRAFT; ANIMAL; APOPTOSIS; BIOSYNTHESIS; CELL PROLIFERATION; DISEASE MODEL; DRUG SCREENING; FEMALE; GENETICS; PATHOLOGY; TUMOR CELL LINE; TUMOR EMBOLISM;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; IMMEDIATE-EARLY PROTEINS; MICE; NEOPLASM METASTASIS; NEOPLASTIC CELLS, CIRCULATING; TRIPLE NEGATIVE BREAST NEOPLASMS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84956587006     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/s13058-016-0673-9     Document Type: Article

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