Does Haptoglobin Phenotype Influence Postnatal Morbidity in Preterm Neonates?

American Journal of Perinatology

Volumn 33, Issue 2, 2015, Pages 130-135

  Kessel, Irena ^a   Leib, Maayan ^a   Levy, Andrew ^a   Miller Lotan, Rachel ^a   Waisman, Dan ^a   Jacobson, Eyal ^b   Rotschild, Avi ^a   Blum, Shany ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b MINISTRY OF HEALTH   (Israel)

Author keywords

haptoglobin phenotypes; inflammation; preterm infants; sepsis

Indexed keywords

HAPTOGLOBIN; OXYGEN;

ARTICLE; ARTIFICIAL VENTILATION; BIRTH WEIGHT; BRAIN HEMORRHAGE; CLINICAL FEATURE; DISEASE COURSE; DISEASE SEVERITY; FEMALE; GESTATIONAL AGE; HUMAN; INFANT; LENGTH OF STAY; LUNG DYSPLASIA; MAJOR CLINICAL STUDY; MALE; MORBIDITY; NECROTIZING ENTEROCOLITIS; OBSERVATIONAL STUDY; OXYGEN THERAPY; PHENOTYPE; POSTNATAL MORBIDITY; PREMATURE LABOR; PREMATURITY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN EXPRESSION; RETROLENTAL FIBROPLASIA; SEPSIS; VERY LOW BIRTH WEIGHT; BRONCHOPULMONARY DYSPLASIA; CEREBRAL HEMORRHAGE; COHORT ANALYSIS; ENTEROCOLITIS, NECROTIZING; GENETICS; INFANT, PREMATURE, DISEASES; ISRAEL; METABOLISM; NEWBORN; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PROTECTION; RETINOPATHY OF PREMATURITY; RISK FACTOR;

BRONCHOPULMONARY DYSPLASIA; CEREBRAL HEMORRHAGE; COHORT STUDIES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENTEROCOLITIS, NECROTIZING; FEMALE; HAPTOGLOBINS; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; ISRAEL; MALE; PHENOTYPE; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDIES; PROTECTIVE FACTORS; RETINOPATHY OF PREMATURITY; RISK FACTORS; SEPSIS;

EID: 84955753425     PISSN: 07351631     EISSN: 10988785     Source Type: Journal    
DOI: 10.1055/s-0035-1560042     Document Type: Article

References (27)

1. Eaton J. W., Brandt P., Mahoney J. R., Lee J. T. Jr. Haptoglobin: a natural bacteriostat. Science: 1982; 215 4533 691 693
2. Bowman B. H., Kurosky A. Haptoglobin: the evolutionary product of duplication, unequal crossing over, and point mutation. Adv Hum Genet: 1982; 12 189 261, 453-454
3. Wassell J. Haptoglobin: function and polymorphism. Clin Lab: 2000; 46 11-12 547 552
4. Sadrzadeh S. M., Bozorgmehr J. Haptoglobin phenotypes in health and disorders. Am J Clin Pathol: 2004; 121 (Suppl): S97 S104
5. Hochberg I., Roguin A., Nikolsky E., Chanderashekhar P. V., Cohen S., Levy A. P. Haptoglobin phenotype and coronary artery collaterals in diabetic patients. Atherosclerosis: 2002; 161 2 441 446
6. Levy A. P., Hochberg I., Jablonski K., et al. Strong Heart Study. Haptoglobin phenotype is an independent risk factor for cardiovascular disease in individuals with diabetes: The Strong Heart Study. J Am Coll Cardiol: 2002; 40 11 1984 1990
7. Guéye P. M., Glasser N., Férard G., Lessinger J. M. Influence of human haptoglobin polymorphism on oxidative stress induced by free hemoglobin on red blood cells. Clin Chem Lab Med: 2006; 44 5 542 547
8. Quaye I. K. Haptoglobin, inflammation and disease. Trans R Soc Trop Med Hyg: 2008; 102 8 735 742
9. Delanghe J., Langlois M., Ouyang J., Claeys G., De Buyzere M., Wuyts B. Effect of haptoglobin phenotypes on growth of Streptococcus pyogenes. Clin Chem Lab Med: 1998; 36 9 691 696
10. Wasserzug O., Blum S., Klement E., Lejbkowicz F., Miller-Lotan R., Levy A. P. Haptoglobin 1-1 genotype and the risk of life-threatening Streptococcus infection: evolutionary implications. J Infect: 2007; 54 4 410
11. Dani C., Cecchi A., Bertini G. Role of oxidative stress as physiopathologic factor in the preterm infant. Minerva Pediatr: 2004; 56 4 381 394
12. Jobe A. H., Bancalari E. Bronchopulmonary dysplasia. Am J Respir Crit Care Med: 2001; 163 7 1723 1729
13. Stoll B. J., Hansen N., Fanaroff A. A., et al. Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network. Pediatrics: 2002; 110 (2 Pt 1): 285 291
14. Bentlin M. R., Suppo de Souza Rugolo L. M. Late-onset sepsis: epidemiology, evaluation, and outcome. NeoReviews: 2010; 11 8 e426 e435
15. Dammann O., Brinkhaus M. J., Bartels D. B., et al. Immaturity, perinatal inflammation, and retinopathy of prematurity: a multi-hit hypothesis. Early Hum Dev: 2009; 85 5 325 329
16. Weinberger B., Laskin D. L., Heck D. E., Laskin J. D. Oxygen toxicity in premature infants. Toxicol Appl Pharmacol: 2002; 181 1 60 67
17. Exploring Proteins and Proteomes. In: Berg J. M., Tymoczko J. L., Stryer L. eds. Biochemistry. 6th ed. New York, NY W. H. Freeman and Company: 2006; 71 73
18. Koch W., Latz W., Eichinger M., et al. Genotyping of the common haptoglobin Hp 1/2 polymorphism based on PCR. Clin Chem: 2002; 48 9 1377 1382
19. Levy N. S., Levy A. P. ELISA for determination of the haptoglobin phenotype. Clin Chem: 2004; 50 11 2148 2150
20. Nanthakumar N., Meng D., Goldstein A. M., et al. The mechanism of excessive intestinal inflammation in necrotizing enterocolitis: an immature innate immune response. PLoS One: 2011; 6 3 e17776
21. Saugstad O. D. Oxidative stress in the newborn-a 30-year perspective. Biol Neonate: 2005; 88 3 228 236
22. Dani C., Cecchi A., Bertini G. Role of oxidative stress as physiopathologic factor in the preterm infant. Minerva Pediatr: 2004; 56 4 381 394
23. Robles R., Palomino N., Robles A. Oxidative stress in the neonate. Early Hum Dev: 2001; 65 (Suppl): S75 S81
24. Mezer E., Makhoul I., Blum S., et al. The role of haptoglobin genotype in the pathogenesis of Retinopathy of Prematurity. J AAPOS: 2012; 16 1 e22
25. Makhoul I. R., Sujov P., Smolkin T., Lusky A., Reichman B. Epidemiological, clinical, and microbiological characteristics of late-onset sepsis among very low birth weight infants in Israel: a national survey. Pediatrics: 2002; 109 1 34 39
26. Buhimschi C. S., Bhandari V., Dulay A. T., et al. Proteomics mapping of cord blood identifies haptoglobin switch-on pattern as biomarker of early-onset neonatal sepsis in preterm newborns. PLoS ONE: 2011; 6 10 e26111
27. Chavez-Bueno S., Beasley J. A., Goldbeck J. M., et al. 'Haptoglobin concentrations in preterm and term newborns' J Perinatol: 2011; 31 7 500 503