메뉴 건너뛰기




Volumn 21, Issue 12, 2015, Pages 1407-1414

Gastric motor dysfunctions in Parkinson's disease: Current pre-clinical evidence

Author keywords

Gastric motility; Gastric neuromuscular functions; Parkinson's disease; Preclinical models of Parkinson's disease

Indexed keywords

ALPHA SYNUCLEIN; DOPAMINE 2 RECEPTOR; DOPAMINE TRANSPORTER; NEURONAL NITRIC OXIDE SYNTHASE; OXIDOPAMINE; CHOLECYSTOKININ; PROTEIN AGGREGATE; ROTENONE;

EID: 84955702998     PISSN: 13538020     EISSN: 18735126     Source Type: Journal    
DOI: 10.1016/j.parkreldis.2015.10.011     Document Type: Review
Times cited : (52)

References (70)
  • 2
    • 0029864459 scopus 로고    scopus 로고
    • Gastric emptying in Parkinson's disease: patients with and without response fluctuations
    • Djaldetti R., Baron J., Ziv I., Melamed E. Gastric emptying in Parkinson's disease: patients with and without response fluctuations. Neurology 1996, 46:1051-1054.
    • (1996) Neurology , vol.46 , pp. 1051-1054
    • Djaldetti, R.1    Baron, J.2    Ziv, I.3    Melamed, E.4
  • 4
    • 0035526250 scopus 로고    scopus 로고
    • Gastric emptying time and gastric motility in patients with Parkinson's disease
    • Hardoff R., Sula M., Tamir A., Soil A., Front A., Badarna S., Giladi N. Gastric emptying time and gastric motility in patients with Parkinson's disease. Mov. Disord. 2001, 16:1041-1047.
    • (2001) Mov. Disord. , vol.16 , pp. 1041-1047
    • Hardoff, R.1    Sula, M.2    Tamir, A.3    Soil, A.4    Front, A.5    Badarna, S.6    Giladi, N.7
  • 6
    • 84937636909 scopus 로고    scopus 로고
    • The frequency and severity of gastrointestinal symptoms in patients with early Parkinson's disease
    • Sung H.Y., Park J.W., Kim J.S. The frequency and severity of gastrointestinal symptoms in patients with early Parkinson's disease. J. Mov. Disord. 2014, 7:7-12.
    • (2014) J. Mov. Disord. , vol.7 , pp. 7-12
    • Sung, H.Y.1    Park, J.W.2    Kim, J.S.3
  • 7
    • 32544442518 scopus 로고    scopus 로고
    • Gastric alpha-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology
    • Braak H., de Vos R.A., Bohl J., Del Tredici K. Gastric alpha-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology. Neurosci. Lett. 2006, 396:67-72.
    • (2006) Neurosci. Lett. , vol.396 , pp. 67-72
    • Braak, H.1    de Vos, R.A.2    Bohl, J.3    Del Tredici, K.4
  • 8
    • 78651096332 scopus 로고    scopus 로고
    • Gastrointestinal dysfunction in Parkinson's disease
    • Pfeiffer R.F. Gastrointestinal dysfunction in Parkinson's disease. Park. Relat. Disord. 2011, 17:10-15.
    • (2011) Park. Relat. Disord. , vol.17 , pp. 10-15
    • Pfeiffer, R.F.1
  • 9
    • 84861197363 scopus 로고    scopus 로고
    • Gastroparesis and Parkinson's disease: a systematic review
    • Heetun Z.S., Quigley E.M. Gastroparesis and Parkinson's disease: a systematic review. Park. Relat. Disord. 2012, 18:433-440.
    • (2012) Park. Relat. Disord. , vol.18 , pp. 433-440
    • Heetun, Z.S.1    Quigley, E.M.2
  • 10
    • 41149110768 scopus 로고    scopus 로고
    • Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: autonomic pathway implicated in Parkinson's disease?
    • Phillips R.J., Walter G.C., Wilder S.L., Baronowsky E.A., Powley T.L. Alpha-synuclein-immunopositive myenteric neurons and vagal preganglionic terminals: autonomic pathway implicated in Parkinson's disease?. Neuroscience 2008, 153:733-750.
    • (2008) Neuroscience , vol.153 , pp. 733-750
    • Phillips, R.J.1    Walter, G.C.2    Wilder, S.L.3    Baronowsky, E.A.4    Powley, T.L.5
  • 11
    • 84922394304 scopus 로고    scopus 로고
    • Gastric dysregulation induced by microinjection of 6-OHDA in the substantia nigra pars compacta of rats is determined by alterations in the brain-gut axis
    • Toti L., Travagli R.A. Gastric dysregulation induced by microinjection of 6-OHDA in the substantia nigra pars compacta of rats is determined by alterations in the brain-gut axis. Am. J. Physiol. Gastrointest. Liver Physiol. 2014, 307:G1013-G1023.
    • (2014) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.307 , pp. G1013-G1023
    • Toti, L.1    Travagli, R.A.2
  • 12
    • 0017333923 scopus 로고
    • Gastric emptying of solid food in normal man and after subtotal gastrectomy and truncal vagotomy with pyloroplasty
    • MacGregor I.L., Martin P., Meyer J.H. Gastric emptying of solid food in normal man and after subtotal gastrectomy and truncal vagotomy with pyloroplasty. Gastroenterology 1977, 72:206-211.
    • (1977) Gastroenterology , vol.72 , pp. 206-211
    • MacGregor, I.L.1    Martin, P.2    Meyer, J.H.3
  • 14
    • 84862501292 scopus 로고    scopus 로고
    • The enteric nervous system and neurogastroenterology
    • Furness J.B. The enteric nervous system and neurogastroenterology. Nat. Rev. Gastroenterol. Hepatol. 2012, 9:286-294.
    • (2012) Nat. Rev. Gastroenterol. Hepatol. , vol.9 , pp. 286-294
    • Furness, J.B.1
  • 15
    • 84909643578 scopus 로고    scopus 로고
    • The enteric nervous system and gastrointestinal innervation: integrated local and central control
    • Furness J.B., Callaghan B.P., Rivera L.R., Cho H.J. The enteric nervous system and gastrointestinal innervation: integrated local and central control. Adv. Exp. Med. Biol. 2014, 817:39-71.
    • (2014) Adv. Exp. Med. Biol. , vol.817 , pp. 39-71
    • Furness, J.B.1    Callaghan, B.P.2    Rivera, L.R.3    Cho, H.J.4
  • 21
    • 29144446911 scopus 로고    scopus 로고
    • Impaired myocardial 123I-metaiodobenzylguanidine uptake in Lewy body disease: comparison between dementia with Lewy bodies and Parkinson's disease
    • Suzuki M., Kurita A., Hashimoto M., Fukumitsu N., Abo M., Ito Y., Urashima M., Inoue K. Impaired myocardial 123I-metaiodobenzylguanidine uptake in Lewy body disease: comparison between dementia with Lewy bodies and Parkinson's disease. J. Neurol. Sci. 2006, 240:15-19.
    • (2006) J. Neurol. Sci. , vol.240 , pp. 15-19
    • Suzuki, M.1    Kurita, A.2    Hashimoto, M.3    Fukumitsu, N.4    Abo, M.5    Ito, Y.6    Urashima, M.7    Inoue, K.8
  • 23
    • 84930663308 scopus 로고    scopus 로고
    • Gastrointestinal biopsies for the diagnosis of alpha-synuclein pathology in Parkinson's disease
    • Cersosimo M.G. Gastrointestinal biopsies for the diagnosis of alpha-synuclein pathology in Parkinson's disease. Gastroenterol. Res. Pract. 2015, 2015:476041.
    • (2015) Gastroenterol. Res. Pract. , vol.2015 , pp. 476041
    • Cersosimo, M.G.1
  • 24
    • 0023174716 scopus 로고
    • Overview of morphological changes in Parkinson's disease
    • Jellinger K. Overview of morphological changes in Parkinson's disease. Adv. Neurol. 1987, 45:1-18.
    • (1987) Adv. Neurol. , vol.45 , pp. 1-18
    • Jellinger, K.1
  • 27
    • 33846419768 scopus 로고    scopus 로고
    • Stanley Fahn lecture 2005: the staging procedure for the inclusion body pathology associated with sporadic Parkinson's disease reconsidered
    • Braak H., Bohl J.R., Muller C.M., Rub U., de Vos R.A., Del Tredici K. Stanley Fahn lecture 2005: the staging procedure for the inclusion body pathology associated with sporadic Parkinson's disease reconsidered. Mov. Disord. 2006, 21:2042-2051.
    • (2006) Mov. Disord. , vol.21 , pp. 2042-2051
    • Braak, H.1    Bohl, J.R.2    Muller, C.M.3    Rub, U.4    de Vos, R.A.5    Del Tredici, K.6
  • 29
    • 40049097822 scopus 로고    scopus 로고
    • Hormones of the gut-brain axis as targets for the treatment of upper gastrointestinal disorders
    • Sanger G.J., Lee K. Hormones of the gut-brain axis as targets for the treatment of upper gastrointestinal disorders. Nat. Rev. Drug Discov. 2008, 7:241-254.
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 241-254
    • Sanger, G.J.1    Lee, K.2
  • 31
    • 0023732489 scopus 로고
    • Cholecystokinin inhibits gastric motility and emptying via a capsaicin-sensitive vagal pathway in rats
    • Raybould H.E., Tache Y. Cholecystokinin inhibits gastric motility and emptying via a capsaicin-sensitive vagal pathway in rats. Am. J. Physiol. 1988, 255:G242-G246.
    • (1988) Am. J. Physiol. , vol.255 , pp. G242-G246
    • Raybould, H.E.1    Tache, Y.2
  • 34
    • 0344394289 scopus 로고    scopus 로고
    • Vagotomy dissociates short- and long-term controls of circulating ghrelin
    • Williams D.L., Grill H.J., Cummings D.E., Kaplan J.M. Vagotomy dissociates short- and long-term controls of circulating ghrelin. Endocrinology 2003, 144:5184-5187.
    • (2003) Endocrinology , vol.144 , pp. 5184-5187
    • Williams, D.L.1    Grill, H.J.2    Cummings, D.E.3    Kaplan, J.M.4
  • 35
    • 79959846783 scopus 로고    scopus 로고
    • Postprandial ghrelin response is reduced in patients with Parkinson's disease and idiopathic REM sleep behaviour disorder: a peripheral biomarker for early Parkinson's disease?
    • Unger M.M., Moller J.C., Mankel K., Eggert K.M., Bohne K., Bodden M., Stiasny-Kolster K., Kann P.H., Mayer G., Tebbe J.J., Oertel W.H. Postprandial ghrelin response is reduced in patients with Parkinson's disease and idiopathic REM sleep behaviour disorder: a peripheral biomarker for early Parkinson's disease?. J. Neurol. 2011, 258:982-990.
    • (2011) J. Neurol. , vol.258 , pp. 982-990
    • Unger, M.M.1    Moller, J.C.2    Mankel, K.3    Eggert, K.M.4    Bohne, K.5    Bodden, M.6    Stiasny-Kolster, K.7    Kann, P.H.8    Mayer, G.9    Tebbe, J.J.10    Oertel, W.H.11
  • 37
    • 0037173006 scopus 로고    scopus 로고
    • Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53--> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice
    • Lee M.K., Stirling W., Xu Y., Xu X., Qui D., Mandir A.S., Dawson T.M., Copeland N.G., Jenkins N.A., Price D.L. Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53--> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:8968-8973.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 8968-8973
    • Lee, M.K.1    Stirling, W.2    Xu, Y.3    Xu, X.4    Qui, D.5    Mandir, A.S.6    Dawson, T.M.7    Copeland, N.G.8    Jenkins, N.A.9    Price, D.L.10
  • 40
    • 9744274529 scopus 로고    scopus 로고
    • Mitochondrial complex I inhibition depletes plasma testosterone in the rotenone model of Parkinson's disease
    • Alam M., Schmidt W.J. Mitochondrial complex I inhibition depletes plasma testosterone in the rotenone model of Parkinson's disease. Physiol. Behav. 2004, 83:395-400.
    • (2004) Physiol. Behav. , vol.83 , pp. 395-400
    • Alam, M.1    Schmidt, W.J.2
  • 41
    • 69749124032 scopus 로고    scopus 로고
    • Chronic rotenone exposure reproduces Parkinson's disease gastrointestinal neuropathology
    • Drolet R.E., Cannon J.R., Montero L., Greenamyre J.T. Chronic rotenone exposure reproduces Parkinson's disease gastrointestinal neuropathology. Neurobiol. Dis. 2009, 36:96-102.
    • (2009) Neurobiol. Dis. , vol.36 , pp. 96-102
    • Drolet, R.E.1    Cannon, J.R.2    Montero, L.3    Greenamyre, J.T.4
  • 42
    • 84859108554 scopus 로고    scopus 로고
    • Animal models of Parkinson's disease
    • Blandini F., Armentero M.T. Animal models of Parkinson's disease. FEBS J. 2012, 279:1156-1166.
    • (2012) FEBS J. , vol.279 , pp. 1156-1166
    • Blandini, F.1    Armentero, M.T.2
  • 43
  • 45
    • 0037118259 scopus 로고    scopus 로고
    • Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein
    • Giasson B.I., Duda J.E., Quinn S.M., Zhang B., Trojanowski J.Q., Lee V.M. Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron 2002, 34:521-533.
    • (2002) Neuron , vol.34 , pp. 521-533
    • Giasson, B.I.1    Duda, J.E.2    Quinn, S.M.3    Zhang, B.4    Trojanowski, J.Q.5    Lee, V.M.6
  • 46
    • 34548230441 scopus 로고    scopus 로고
    • Loss of enteric dopaminergic neurons and associated changes in colon motility in an MPTP mouse model of Parkinson's disease
    • Anderson G., Noorian A.R., Taylor G., Anitha M., Bernhard D., Srinivasan S., Greene J.G. Loss of enteric dopaminergic neurons and associated changes in colon motility in an MPTP mouse model of Parkinson's disease. Exp. Neurol. 2007, 207:4-12.
    • (2007) Exp. Neurol. , vol.207 , pp. 4-12
    • Anderson, G.1    Noorian, A.R.2    Taylor, G.3    Anitha, M.4    Bernhard, D.5    Srinivasan, S.6    Greene, J.G.7
  • 48
    • 67349122370 scopus 로고    scopus 로고
    • Delayed gastric emptying and enteric nervous system dysfunction in the rotenone model of Parkinson's disease
    • Greene J.G., Noorian A.R., Srinivasan S. Delayed gastric emptying and enteric nervous system dysfunction in the rotenone model of Parkinson's disease. Exp. Neurol. 2009, 218:154-161.
    • (2009) Exp. Neurol. , vol.218 , pp. 154-161
    • Greene, J.G.1    Noorian, A.R.2    Srinivasan, S.3
  • 49
    • 80055057793 scopus 로고    scopus 로고
    • Reduced expression of choline acetyltransferase in vagal motoneurons and gastric motor dysfunction in a 6-OHDA rat model of Parkinson's disease
    • Zheng L.F., Wang Z.Y., Li X.F., Song J., Hong F., Lian H., Wang Q., Feng X.Y., Tang Y.Y., Zhang Y., Zhu J.X. Reduced expression of choline acetyltransferase in vagal motoneurons and gastric motor dysfunction in a 6-OHDA rat model of Parkinson's disease. Brain Res. 2011, 1420:59-67.
    • (2011) Brain Res. , vol.1420 , pp. 59-67
    • Zheng, L.F.1    Wang, Z.Y.2    Li, X.F.3    Song, J.4    Hong, F.5    Lian, H.6    Wang, Q.7    Feng, X.Y.8    Tang, Y.Y.9    Zhang, Y.10    Zhu, J.X.11
  • 50
    • 84859712673 scopus 로고    scopus 로고
    • Gastrointestinal dysfunction in a Parkinson's disease rat model and the changes of dopaminergic, nitric oxidergic, and cholinergic neurotransmitters in myenteric plexus
    • Zhu H.C., Zhao J., Luo C.Y., Li Q.Q. Gastrointestinal dysfunction in a Parkinson's disease rat model and the changes of dopaminergic, nitric oxidergic, and cholinergic neurotransmitters in myenteric plexus. J. Mol. Neurosci. 2012, 47:15-25.
    • (2012) J. Mol. Neurosci. , vol.47 , pp. 15-25
    • Zhu, H.C.1    Zhao, J.2    Luo, C.Y.3    Li, Q.Q.4
  • 52
    • 84900528499 scopus 로고    scopus 로고
    • The role of the vagal pathway and gastric dopamine in the gastroparesis of rats after a 6-hydroxydopamine microinjection in the substantia nigra
    • Zheng L.F., Song J., Fan R.F., Chen C.L., Ren Q.Z., Zhang X.L., Feng X.Y., Zhang Y., Li L.S., Zhu J.X. The role of the vagal pathway and gastric dopamine in the gastroparesis of rats after a 6-hydroxydopamine microinjection in the substantia nigra. Acta Physiol. 2014, 211:434-446.
    • (2014) Acta Physiol. , vol.211 , pp. 434-446
    • Zheng, L.F.1    Song, J.2    Fan, R.F.3    Chen, C.L.4    Ren, Q.Z.5    Zhang, X.L.6    Feng, X.Y.7    Zhang, Y.8    Li, L.S.9    Zhu, J.X.10
  • 53
    • 84883746135 scopus 로고    scopus 로고
    • Alterations in TH- and ChAT-immunoreactive neurons in the DMV and gastric dysmotility in an LPS-induced PD rat model
    • Zheng L.F., Zhang Y., Chen C.L., Song J., Fan R.F., Cai Q.Q., Wang Z.Y., Zhu J.X. Alterations in TH- and ChAT-immunoreactive neurons in the DMV and gastric dysmotility in an LPS-induced PD rat model. Auton. Neurosci. 2013, 177:194-198.
    • (2013) Auton. Neurosci. , vol.177 , pp. 194-198
    • Zheng, L.F.1    Zhang, Y.2    Chen, C.L.3    Song, J.4    Fan, R.F.5    Cai, Q.Q.6    Wang, Z.Y.7    Zhu, J.X.8
  • 54
    • 84902548422 scopus 로고    scopus 로고
    • Upregulation of beta1-adrenoceptors is involved in the formation of gastric dysmotility in the 6-hydroxydopamine rat model of Parkinson's disease
    • Song J., Zheng L., Zhang X., Feng X., Fan R., Sun L., Hong F., Zhang Y., Zhu J. Upregulation of beta1-adrenoceptors is involved in the formation of gastric dysmotility in the 6-hydroxydopamine rat model of Parkinson's disease. Transl. Res. 2014, 164:22-31.
    • (2014) Transl. Res. , vol.164 , pp. 22-31
    • Song, J.1    Zheng, L.2    Zhang, X.3    Feng, X.4    Fan, R.5    Sun, L.6    Hong, F.7    Zhang, Y.8    Zhu, J.9
  • 56
    • 33644829284 scopus 로고    scopus 로고
    • Physiological modulation of intestinal motility by enteric dopaminergic neurons and the D2 receptor: analysis of dopamine receptor expression, location, development, and function in wild-type and knock-out mice
    • Li Z.S., Schmauss C., Cuenca A., Ratcliffe E., Gershon M.D. Physiological modulation of intestinal motility by enteric dopaminergic neurons and the D2 receptor: analysis of dopamine receptor expression, location, development, and function in wild-type and knock-out mice. J Neurosci. 2006, 26:2798-2807.
    • (2006) J Neurosci. , vol.26 , pp. 2798-2807
    • Li, Z.S.1    Schmauss, C.2    Cuenca, A.3    Ratcliffe, E.4    Gershon, M.D.5
  • 57
    • 0025761997 scopus 로고
    • Autonomic nervous system disorders in Parkinson's disease
    • Takahashi A. Autonomic nervous system disorders in Parkinson's disease. Eur. Neurol. 1991, 31(Suppl. 1):41-47.
    • (1991) Eur. Neurol. , vol.31 , pp. 41-47
    • Takahashi, A.1
  • 58
    • 43049145789 scopus 로고    scopus 로고
    • Alteration of dopaminergic markers in gastrointestinal tract of different rodent models of Parkinson's disease
    • Tian Y.M., Chen X., Luo D.Z., Zhang X.H., Xue H., Zheng L.F., Yang N., Wang X.M., Zhu J.X. Alteration of dopaminergic markers in gastrointestinal tract of different rodent models of Parkinson's disease. Neuroscience 2008, 153:634-644.
    • (2008) Neuroscience , vol.153 , pp. 634-644
    • Tian, Y.M.1    Chen, X.2    Luo, D.Z.3    Zhang, X.H.4    Xue, H.5    Zheng, L.F.6    Yang, N.7    Wang, X.M.8    Zhu, J.X.9
  • 61
    • 36248985106 scopus 로고    scopus 로고
    • Update on the genetics of Parkinson's disease
    • Gasser T. Update on the genetics of Parkinson's disease. Mov. Disord. 2007, 22(Suppl. 17):S343-S350.
    • (2007) Mov. Disord. , vol.22 , pp. S343-S350
    • Gasser, T.1
  • 63
    • 84863662763 scopus 로고    scopus 로고
    • Alpha-synuclein transgenic mice display age-related slowing of gastrointestinal motility associated with transgene expression in the vagal system
    • Noorian A.R., Rha J., Annerino D.M., Bernhard D., Taylor G.M., Greene J.G. Alpha-synuclein transgenic mice display age-related slowing of gastrointestinal motility associated with transgene expression in the vagal system. Neurobiol. Dis. 2012, 48:9-19.
    • (2012) Neurobiol. Dis. , vol.48 , pp. 9-19
    • Noorian, A.R.1    Rha, J.2    Annerino, D.M.3    Bernhard, D.4    Taylor, G.M.5    Greene, J.G.6
  • 64
    • 77952478217 scopus 로고    scopus 로고
    • Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated alpha-synuclein gene mutations precede central nervous system changes
    • Kuo Y.M., Li Z., Jiao Y., Gaborit N., Pani A.K., Orrison B.M., Bruneau B.G., Giasson B.I., Smeyne R.J., Gershon M.D., Nussbaum R.L. Extensive enteric nervous system abnormalities in mice transgenic for artificial chromosomes containing Parkinson disease-associated alpha-synuclein gene mutations precede central nervous system changes. Hum. Mol. Genet. 2010, 19:1633-1650.
    • (2010) Hum. Mol. Genet. , vol.19 , pp. 1633-1650
    • Kuo, Y.M.1    Li, Z.2    Jiao, Y.3    Gaborit, N.4    Pani, A.K.5    Orrison, B.M.6    Bruneau, B.G.7    Giasson, B.I.8    Smeyne, R.J.9    Gershon, M.D.10    Nussbaum, R.L.11
  • 66
    • 84881376726 scopus 로고    scopus 로고
    • Advances in the genetics of Parkinson disease
    • Trinh J., Farrer M. Advances in the genetics of Parkinson disease. Nat. Rev. Neurol. 2013, 9:445-454.
    • (2013) Nat. Rev. Neurol. , vol.9 , pp. 445-454
    • Trinh, J.1    Farrer, M.2
  • 68
    • 0038748401 scopus 로고    scopus 로고
    • Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen
    • Braak H., Rüb U., Gai W.P., Del Tredici K. Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen. J. Neural Transm. 2003, 110:517-536.
    • (2003) J. Neural Transm. , vol.110 , pp. 517-536
    • Braak, H.1    Rüb, U.2    Gai, W.P.3    Del Tredici, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.