메뉴 건너뛰기




Volumn 263, Issue 1, 2016, Pages 177-178

Relaunching an old drug: the potential role of bexarotene in neurodegenerative diseases

Author keywords

[No Author keywords available]

Indexed keywords

BEXAROTENE; NEUROPROTECTIVE AGENT; RETINOIC ACID RECEPTOR; TETRALIN DERIVATIVE;

EID: 84955692149     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-015-8004-0     Document Type: Letter
Times cited : (11)

References (15)
  • 1
    • 84897147399 scopus 로고    scopus 로고
    • Nuclear receptors, RXR, and the big bang
    • COI: 1:CAS:528:DC%2BC2cXmtVCqsLw%3D, PID: 24679540
    • Evans RM, Mangelsdorf DJ (2014) Nuclear receptors, RXR, and the big bang. Cell 157(1):255–266
    • (2014) Cell , vol.157 , Issue.1 , pp. 255-266
    • Evans, R.M.1    Mangelsdorf, D.J.2
  • 2
    • 18844405941 scopus 로고    scopus 로고
    • Role of retinoid signalling in the adult brain
    • COI: 1:CAS:528:DC%2BD2MXktVOntb0%3D, PID: 15882777
    • Lane MA, Bailey SJ (2005) Role of retinoid signalling in the adult brain. Prog Neurobiol 75(4):275–293
    • (2005) Prog Neurobiol , vol.75 , Issue.4 , pp. 275-293
    • Lane, M.A.1    Bailey, S.J.2
  • 3
    • 1842689602 scopus 로고    scopus 로고
    • Bexarotene: a clinical review
    • COI: 1:CAS:528:DC%2BD2cXislyrur8%3D, PID: 15056048
    • Farol LT, Hymes KB (2004) Bexarotene: a clinical review. Expert Rev Anticancer Ther 4(2):180–188
    • (2004) Expert Rev Anticancer Ther , vol.4 , Issue.2 , pp. 180-188
    • Farol, L.T.1    Hymes, K.B.2
  • 4
    • 84862777666 scopus 로고    scopus 로고
    • ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models
    • COI: 1:CAS:528:DC%2BC38XktFWksbY%3D, PID: 22323736
    • Cramer PE, Cirrito JR, Wesson DW, Lee CY, Karlo JC, Zinn AE et al (2012) ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models. Science 335(6075):1503–1506
    • (2012) Science , vol.335 , Issue.6075 , pp. 1503-1506
    • Cramer, P.E.1    Cirrito, J.R.2    Wesson, D.W.3    Lee, C.Y.4    Karlo, J.C.5    Zinn, A.E.6
  • 5
    • 84877950101 scopus 로고    scopus 로고
    • Comment on “ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models
    • COI: 1:CAS:528:DC%2BC3sXnvFSrur8%3D, PID: 23704552
    • Fitz NF, Cronican AA, Lefterov I, Koldamova R (2013) Comment on “ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models”. Science 340(6135):924
    • (2013) Science , vol.340 , Issue.6135 , pp. 924
    • Fitz, N.F.1    Cronican, A.A.2    Lefterov, I.3    Koldamova, R.4
  • 6
    • 84877950101 scopus 로고    scopus 로고
    • Comment on “ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models
    • COI: 1:CAS:528:DC%2BC3sXnvFSrurg%3D, PID: 23704554
    • Tesseur I, Lo AC, Roberfroid A, Dietvorst S, Van Broeck B, Borgers M et al (2013) Comment on “ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models”. Science 340(6135):924
    • (2013) Science , vol.340 , Issue.6135 , pp. 924
    • Tesseur, I.1    Lo, A.C.2    Roberfroid, A.3    Dietvorst, S.4    Van Broeck, B.5    Borgers, M.6
  • 7
    • 84877986239 scopus 로고    scopus 로고
    • Comment on “ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models
    • COI: 1:CAS:528:DC%2BC3sXnvFSrur0%3D, PID: 23704553
    • Price AR, Xu G, Siemienski ZB, Smithson LA, Borchelt DR, Golde TE et al (2013) Comment on “ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models”. Science 340(6135):924
    • (2013) Science , vol.340 , Issue.6135 , pp. 924
    • Price, A.R.1    Xu, G.2    Siemienski, Z.B.3    Smithson, L.A.4    Borchelt, D.R.5    Golde, T.E.6
  • 8
    • 84877986239 scopus 로고    scopus 로고
    • Comment on “ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models
    • COI: 1:CAS:528:DC%2BC3sXnvFSrurY%3D, PID: 23704555
    • Veeraraghavalu K, Zhang C, Miller S, Hefendehl JK, Rajapaksha TW, Ulrich J et al (2013) Comment on “ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models”. Science 340(6135):924
    • (2013) Science , vol.340 , Issue.6135 , pp. 924
    • Veeraraghavalu, K.1    Zhang, C.2    Miller, S.3    Hefendehl, J.K.4    Rajapaksha, T.W.5    Ulrich, J.6
  • 9
    • 84877986239 scopus 로고    scopus 로고
    • Response to comments on “ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models
    • COI: 1:CAS:528:DC%2BC3sXnvFSru74%3D, PID: 23704556
    • Landreth GE, Cramer PE, Lakner MM, Cirrito JR, Wesson DW, Brunden KR et al (2013) Response to comments on “ApoE-directed therapeutics rapidly clear beta-amyloid and reverse deficits in AD mouse models”. Science 340(6135):924
    • (2013) Science , vol.340 , Issue.6135 , pp. 924
    • Landreth, G.E.1    Cramer, P.E.2    Lakner, M.M.3    Cirrito, J.R.4    Wesson, D.W.5    Brunden, K.R.6
  • 10
    • 84902084909 scopus 로고    scopus 로고
    • Bexarotene reduces network excitability in models of Alzheimer’s disease and epilepsy
    • COI: 1:CAS:528:DC%2BC2cXmvVWrtb4%3D, PID: 24767949
    • Bomben V, Holth J, Reed J, Cramer P, Landreth G, Noebels J (2014) Bexarotene reduces network excitability in models of Alzheimer’s disease and epilepsy. Neurobiol Aging 35(9):2091–2095
    • (2014) Neurobiol Aging , vol.35 , Issue.9 , pp. 2091-2095
    • Bomben, V.1    Holth, J.2    Reed, J.3    Cramer, P.4    Landreth, G.5    Noebels, J.6
  • 11
    • 84934964053 scopus 로고    scopus 로고
    • RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment
    • COI: 1:CAS:528:DC%2BC2MXhtVegtLbE, PID: 26071899
    • Lefterov I, Schug J, Mounier A, Nam KN, Fitz NF, Koldamova R (2015) RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment. Neurobiol Dis 82:132–140
    • (2015) Neurobiol Dis , vol.82 , pp. 132-140
    • Lefterov, I.1    Schug, J.2    Mounier, A.3    Nam, K.N.4    Fitz, N.F.5    Koldamova, R.6
  • 12
    • 84930458042 scopus 로고    scopus 로고
    • The continuing failure of bexarotene in Alzheimer’s disease mice
    • COI: 1:CAS:528:DC%2BC2MXps12ls7g%3D, PID: 25777514
    • Balducci C, Paladini A, Micotti E, Tolomeo D, La Vitola P, Grigoli E et al (2015) The continuing failure of bexarotene in Alzheimer’s disease mice. J Alzheimers Dis 46(2):471–482
    • (2015) J Alzheimers Dis , vol.46 , Issue.2 , pp. 471-482
    • Balducci, C.1    Paladini, A.2    Micotti, E.3    Tolomeo, D.4    La Vitola, P.5    Grigoli, E.6
  • 14
    • 84888380533 scopus 로고    scopus 로고
    • Low dose bexarotene treatment rescues dopamine neurons and restores behavioral function in models of Parkinson’s disease
    • COI: 1:CAS:528:DC%2BC3sXhs1SgsLrN, PID: 24117438
    • McFarland K, Spalding TA, Hubbard D, Ma JN, Olsson R, Burstein ES (2013) Low dose bexarotene treatment rescues dopamine neurons and restores behavioral function in models of Parkinson’s disease. ACS Chem Neurosci 4(11):1430–1438
    • (2013) ACS Chem Neurosci , vol.4 , Issue.11 , pp. 1430-1438
    • McFarland, K.1    Spalding, T.A.2    Hubbard, D.3    Ma, J.N.4    Olsson, R.5    Burstein, E.S.6
  • 15
    • 84908259585 scopus 로고    scopus 로고
    • Compensatory motor neuron response to chromatolysis in the murine hSOD1 G93A model of amyotrophic lateral sclerosis
    • PID: 25374511
    • Riancho J, Ruiz-Soto M, Villagrá NT, Berciano J, Berciano MT, Lafarga M (2014) Compensatory motor neuron response to chromatolysis in the murine hSOD1 G93A model of amyotrophic lateral sclerosis. Front Cell Neurosci 8:346
    • (2014) Front Cell Neurosci , vol.8 , pp. 346
    • Riancho, J.1    Ruiz-Soto, M.2    Villagrá, N.T.3    Berciano, J.4    Berciano, M.T.5    Lafarga, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.