메뉴 건너뛰기




Volumn 86, Issue 6, 2015, Pages 1065-1075

Empirical Drug Therapy for Idiopathic Male Infertility: What is the New Evidence?

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ARGININE; AROMATASE INHIBITOR; CARNITINE; CAROTENOID; GLUTATHIONE; GONADOTROPIN; LYCOPENE; SELECTIVE ESTROGEN RECEPTOR MODULATOR; UBIDECARENONE; UBIQUINONE;

EID: 84955638859     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2015.07.030     Document Type: Review
Times cited : (36)

References (55)
  • 2
    • 33748116737 scopus 로고    scopus 로고
    • Drug therapy for idiopathic male infertility: Rationale versus evidence
    • R. Kumar, G. Gautam, and N.P. Gupta Drug therapy for idiopathic male infertility: rationale versus evidence J Urol 176 4 Pt 1 2006 1307 1312
    • (2006) J Urol , vol.176 , Issue.4 , pp. 1307-1312
    • Kumar, R.1    Gautam, G.2    Gupta, N.P.3
  • 3
    • 85027945013 scopus 로고    scopus 로고
    • Factors affecting spermatogenesis upon gonadotropin replacement therapy: A metaanalytic study
    • G. Rastrelli, G. Corona, E. Mannucci, and et al. Factors affecting spermatogenesis upon gonadotropin replacement therapy: a metaanalytic study Andrology 2 2014 794 808
    • (2014) Andrology , vol.2 , pp. 794-808
    • Rastrelli, G.1    Corona, G.2    Mannucci, E.3
  • 4
    • 33748101911 scopus 로고    scopus 로고
    • Effects of high doses of recombinant human follicle stimulating hormone in the treatment of male factor infertility: Results of a pilot study
    • R. Paradisi, P. Busacchi, R. Seracchioli, and et al. Effects of high doses of recombinant human follicle stimulating hormone in the treatment of male factor infertility: results of a pilot study Fertil Steril 86 2006 728 731
    • (2006) Fertil Steril , vol.86 , pp. 728-731
    • Paradisi, R.1    Busacchi, P.2    Seracchioli, R.3
  • 6
    • 84866361860 scopus 로고    scopus 로고
    • Recombinant human FSH reduces sperm DNA fragmentation in men with idiopathic oligoasthenoteratozoospermia
    • N. Colacurci, M.G. Monti, F. Fornaro, and et al. Recombinant human FSH reduces sperm DNA fragmentation in men with idiopathic oligoasthenoteratozoospermia J Androl 33 2012 588 593
    • (2012) J Androl , vol.33 , pp. 588-593
    • Colacurci, N.1    Monti, M.G.2    Fornaro, F.3
  • 8
    • 78751571033 scopus 로고    scopus 로고
    • The effect of aromatase inhibitor letrozole on body mass index, serum hormones and sperm parameters in infertile men
    • B. Saylam, O. Efesoy, and S. Cayan The effect of aromatase inhibitor letrozole on body mass index, serum hormones and sperm parameters in infertile men Fertil Steril 95 2011 809 811
    • (2011) Fertil Steril , vol.95 , pp. 809-811
    • Saylam, B.1    Efesoy, O.2    Cayan, S.3
  • 9
    • 84862993267 scopus 로고    scopus 로고
    • Changes in hormonal profile and seminal parameters with use of aromatase inhibitors in management of infertile men with low testosterone to estradiol ratios
    • O. Gregoriou, P. Bakas, C. Grigoriadis, and et al. Changes in hormonal profile and seminal parameters with use of aromatase inhibitors in management of infertile men with low testosterone to estradiol ratios Fertil Steril 98 2012 48 51
    • (2012) Fertil Steril , vol.98 , pp. 48-51
    • Gregoriou, O.1    Bakas, P.2    Grigoriadis, C.3
  • 10
    • 84887237194 scopus 로고    scopus 로고
    • Multivariate analysis to predict letrozole efficacy in improving sperm count of non-obstructive azoospermic and cryptozoospermic patients: A pilot study
    • G. Cavallini, G. Biagiotti, and E. Bolzon Multivariate analysis to predict letrozole efficacy in improving sperm count of non-obstructive azoospermic and cryptozoospermic patients: a pilot study Asian J Androl 15 2013 806 811
    • (2013) Asian J Androl , vol.15 , pp. 806-811
    • Cavallini, G.1    Biagiotti, G.2    Bolzon, E.3
  • 11
    • 84933506295 scopus 로고    scopus 로고
    • Sperm concentration is poorly associated with hypoandrogenism in infertile men
    • D.P. Patel, W.O. Brant, J.B. Myers, and et al. Sperm concentration is poorly associated with hypoandrogenism in infertile men Urology 85 2015 1062 1067
    • (2015) Urology , vol.85 , pp. 1062-1067
    • Patel, D.P.1    Brant, W.O.2    Myers, J.B.3
  • 12
    • 84939549782 scopus 로고    scopus 로고
    • A randomized prospective double-blind comparison trial of clomiphene citrate and anastrozole in raising testosterone in hypogonadal infertile men
    • Accessed July 24, 2015
    • S. Helo, J. Ellen, C. Mechlin, and et al. A randomized prospective double-blind comparison trial of clomiphene citrate and anastrozole in raising testosterone in hypogonadal infertile men J Sex Med 2015 10.1111/jsm.12944 Accessed July 24, 2015
    • (2015) J Sex Med
    • Helo, S.1    Ellen, J.2    Mechlin, C.3
  • 13
    • 34547872379 scopus 로고    scopus 로고
    • Effect of clomiphene citrate on sperm density in male partners of infertile couples
    • S.S. Patankar, S.B. Kaore, M.V. Sawane, and et al. Effect of clomiphene citrate on sperm density in male partners of infertile couples Indian J Physiol Pharmacol 51 2007 195 198
    • (2007) Indian J Physiol Pharmacol , vol.51 , pp. 195-198
    • Patankar, S.S.1    Kaore, S.B.2    Sawane, M.V.3
  • 14
    • 72049097916 scopus 로고    scopus 로고
    • Role of testosterone/estradiol ratio in predicting the efficacy of tamoxifen citrate treatment in idiopathic oligoasthenoteratozoospermic men
    • M. Cakan, M. Aldemir, M. Topcuoglu, and et al. Role of testosterone/estradiol ratio in predicting the efficacy of tamoxifen citrate treatment in idiopathic oligoasthenoteratozoospermic men Urol Int 83 2009 446 451
    • (2009) Urol Int , vol.83 , pp. 446-451
    • Cakan, M.1    Aldemir, M.2    Topcuoglu, M.3
  • 15
    • 78649757817 scopus 로고    scopus 로고
    • Safety and efficacy of clomiphene citrate and L-carnitine in idiopathic male infertility: A comparative study
    • M. Moradi, A. Moradi, M. Alemi, and et al. Safety and efficacy of clomiphene citrate and L-carnitine in idiopathic male infertility: a comparative study Urol J 7 2010 188 193
    • (2010) Urol J , vol.7 , pp. 188-193
    • Moradi, M.1    Moradi, A.2    Alemi, M.3
  • 16
    • 84879791379 scopus 로고    scopus 로고
    • Tamoxifen combined with coenzyme Q10 for idiopathic oligoasthenospermia
    • K.F. Tang, Y. Xing, C.Y. Wu, and et al. Tamoxifen combined with coenzyme Q10 for idiopathic oligoasthenospermia Zhonghua Nan Ke Xue 17 2011 615 618
    • (2011) Zhonghua Nan Ke Xue , vol.17 , pp. 615-618
    • Tang, K.F.1    Xing, Y.2    Wu, C.Y.3
  • 17
    • 84938293986 scopus 로고    scopus 로고
    • Efficacy of tamoxifen and l-carnitine on sperm ultrastructure and seminal oxidative stress in patients with idiopathic oligoasthenoteratozoospermia
    • Epub. Accessed March 15, 2015
    • E.A. Nada, M.A. El Taieb, H.M. Ibrahim, and A.E. Al Saied Efficacy of tamoxifen and l-carnitine on sperm ultrastructure and seminal oxidative stress in patients with idiopathic oligoasthenoteratozoospermia Andrologia 2014 10.1111/and.12333 Epub. Accessed March 15, 2015
    • (2014) Andrologia
    • Nada, E.A.1    El Taieb, M.A.2    Ibrahim, H.M.3    Al Saied, A.E.4
  • 18
    • 84883014073 scopus 로고    scopus 로고
    • Revisiting oestrogen antagonists (clomiphene or tamoxifen) as medical empiric therapy for idiopathic male infertility: A meta-analysis
    • M.E. Chua, K.G. Escusa, S. Luna, and et al. Revisiting oestrogen antagonists (clomiphene or tamoxifen) as medical empiric therapy for idiopathic male infertility: a meta-analysis Andrology 1 2013 749 757
    • (2013) Andrology , vol.1 , pp. 749-757
    • Chua, M.E.1    Escusa, K.G.2    Luna, S.3
  • 19
    • 26944485833 scopus 로고    scopus 로고
    • Clomiphene administration for cases of non obstructive azoospermia: A multicenter study
    • A. Hussein, Y. Ozgok, L. Ross, and et al. Clomiphene administration for cases of non obstructive azoospermia: a multicenter study J Androl 26 2005 787 791
    • (2005) J Androl , vol.26 , pp. 787-791
    • Hussein, A.1    Ozgok, Y.2    Ross, L.3
  • 20
    • 84861516234 scopus 로고    scopus 로고
    • Beneficial effect of tamoxifen on sperm recovery in infertile men with non obstructive azoospermia
    • M.R. Moein, N. Tabibnejad, and J. Ghasemzadeh Beneficial effect of tamoxifen on sperm recovery in infertile men with non obstructive azoospermia Andrologia 44 2012 194 198
    • (2012) Andrologia , vol.44 , pp. 194-198
    • Moein, M.R.1    Tabibnejad, N.2    Ghasemzadeh, J.3
  • 21
    • 77957777948 scopus 로고    scopus 로고
    • A systematic review of the effect of oral antioxidants on male infertility
    • C. Ross, A. Morriss, M. Khairy, and et al. A systematic review of the effect of oral antioxidants on male infertility Reprod Biomed Online 20 2010 711 723
    • (2010) Reprod Biomed Online , vol.20 , pp. 711-723
    • Ross, C.1    Morriss, A.2    Khairy, M.3
  • 22
    • 79954524734 scopus 로고    scopus 로고
    • Oxidative stress and antioxidants for idiopathic oligoasthenoteratospermia: Is it justified?
    • A. Agarwal, and L.H. Sekhon Oxidative stress and antioxidants for idiopathic oligoasthenoteratospermia: is it justified? Indian J Urol 27 2011 74 85
    • (2011) Indian J Urol , vol.27 , pp. 74-85
    • Agarwal, A.1    Sekhon, L.H.2
  • 23
    • 84876813382 scopus 로고    scopus 로고
    • Association of oxidative stress biomarkers and antioxidant enzymatic activity in male infertility of north-east India
    • R. Mahanta, A. Gogoi, P.N. Chaudhury, and et al. Association of oxidative stress biomarkers and antioxidant enzymatic activity in male infertility of north-east India J Obstet Gynaecol India 62 2012 546 550
    • (2012) J Obstet Gynaecol India , vol.62 , pp. 546-550
    • Mahanta, R.1    Gogoi, A.2    Chaudhury, P.N.3
  • 24
    • 70349391109 scopus 로고    scopus 로고
    • Glutathione S-transferase M1 and T1 polymorphism in men with idiopathic infertility
    • A.C. Finotti, R.C. Costa E Silva, B.M. Bordin, and et al. Glutathione S-transferase M1 and T1 polymorphism in men with idiopathic infertility Genet Mol Res 8 2009 1093 1098
    • (2009) Genet Mol Res , vol.8 , pp. 1093-1098
    • Finotti, A.C.1    Costa Silva, E.R.C.2    Bordin, B.M.3
  • 25
    • 84859164092 scopus 로고    scopus 로고
    • Glutathione peroxidase activity in seminal plasma and its relationship to classical sperm parameters and in vitro fertilization-intracytoplasmic sperm injection outcome
    • L. Crisol, R. Matorras, F. Aspichueta, and et al. Glutathione peroxidase activity in seminal plasma and its relationship to classical sperm parameters and in vitro fertilization-intracytoplasmic sperm injection outcome Fertil Steril 97 2012 852 857
    • (2012) Fertil Steril , vol.97 , pp. 852-857
    • Crisol, L.1    Matorras, R.2    Aspichueta, F.3
  • 26
    • 84888432389 scopus 로고    scopus 로고
    • Semen quality in relation to antioxidant intake in a healthy male population
    • P. Zareba, D.S. Colaci, M. Afeiche, and et al. Semen quality in relation to antioxidant intake in a healthy male population Fertil Steril 100 2013 1572 1579
    • (2013) Fertil Steril , vol.100 , pp. 1572-1579
    • Zareba, P.1    Colaci, D.S.2    Afeiche, M.3
  • 27
    • 77955580402 scopus 로고    scopus 로고
    • Lycopene supplementation in vitro can protect human sperm deoxyribonucleic acid from oxidative damage
    • A. Zini, M. San Gabriel, and J. Libman Lycopene supplementation in vitro can protect human sperm deoxyribonucleic acid from oxidative damage Fertil Steril 94 2010 1033 1036
    • (2010) Fertil Steril , vol.94 , pp. 1033-1036
    • Zini, A.1    San Gabriel, M.2    Libman, J.3
  • 28
    • 84924515394 scopus 로고    scopus 로고
    • Lycopene improves the distorted ratio between AA/DHA in the seminal plasma of infertile males and increases the likelihood of successful pregnancy
    • R. Filipcikova, I. Oborna, J. Brezinova, and et al. Lycopene improves the distorted ratio between AA/DHA in the seminal plasma of infertile males and increases the likelihood of successful pregnancy Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 159 2015 77 82
    • (2015) Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub , vol.159 , pp. 77-82
    • Filipcikova, R.1    Oborna, I.2    Brezinova, J.3
  • 29
    • 77955944267 scopus 로고    scopus 로고
    • Deficiency of alpha-tocopherol in seminal fluid as a probable factor in low fertility in Côte d'Ivoire
    • F. Diafouka, and G.K. Gbassi Deficiency of alpha-tocopherol in seminal fluid as a probable factor in low fertility in Côte d'Ivoire Afr J Reprod Health 13 2009 123 125
    • (2009) Afr J Reprod Health , vol.13 , pp. 123-125
    • Diafouka, F.1    Gbassi, G.K.2
  • 30
    • 70449102776 scopus 로고    scopus 로고
    • Factors contributing to gender differences in serum retinol and alpha-tocopherol in infertile couples
    • M.K. Al-Azemi, A.E. Omu, T. Fatinikun, and et al. Factors contributing to gender differences in serum retinol and alpha-tocopherol in infertile couples Reprod Biomed Online 19 2009 583 590
    • (2009) Reprod Biomed Online , vol.19 , pp. 583-590
    • Al-Azemi, M.K.1    Omu, A.E.2    Fatinikun, T.3
  • 31
    • 84857033815 scopus 로고    scopus 로고
    • In vitro effects of α tocopherol on teratozoospermic semen samples
    • S. Keshtgar, H. Fanaei, S. Bahmanpour, and et al. In vitro effects of α tocopherol on teratozoospermic semen samples Andrologia 44 2012 721 727
    • (2012) Andrologia , vol.44 , pp. 721-727
    • Keshtgar, S.1    Fanaei, H.2    Bahmanpour, S.3
  • 32
    • 84874815325 scopus 로고    scopus 로고
    • Efficacy of natural vitamin e on oligospermia and asthenospermia: A prospective multi-centered randomized controlled study of 106 cases
    • X.F. Chen, Z. Li, P. Ping, and et al. Efficacy of natural vitamin E on oligospermia and asthenospermia: a prospective multi-centered randomized controlled study of 106 cases Zhonghua Nan Ke Xue 18 2012 428 431
    • (2012) Zhonghua Nan Ke Xue , vol.18 , pp. 428-431
    • Chen, X.F.1    Li, Z.2    Ping, P.3
  • 34
    • 79960766859 scopus 로고    scopus 로고
    • Role of L-carnitine in male infertility
    • S.D. Ahmed, K.A. Karira, Jagdesh, and et al. Role of L-carnitine in male infertility J Pak Med Assoc 61 2011 732 736
    • (2011) J Pak Med Assoc , vol.61 , pp. 732-736
    • Ahmed, S.D.1    Karira, K.A.2    Jagdesh3
  • 35
    • 77957652356 scopus 로고    scopus 로고
    • Expressions of sperm-specific genes in carnitine-cultured testis sperm of obstructive azoospermia patients
    • J.Z. Shi, S.S. Zhang, Z. Zhang, and et al. Expressions of sperm-specific genes in carnitine-cultured testis sperm of obstructive azoospermia patients Zhonghua Nan Ke Xue 16 2010 504 509
    • (2010) Zhonghua Nan Ke Xue , vol.16 , pp. 504-509
    • Shi, J.Z.1    Zhang, S.S.2    Zhang, Z.3
  • 36
    • 84904290745 scopus 로고    scopus 로고
    • Cryoprotective effect of l-carnitine on motility, vitality and DNA oxidation of human spermatozoa
    • S. Banihani, A. Agarwal, R. Sharma, and et al. Cryoprotective effect of l-carnitine on motility, vitality and DNA oxidation of human spermatozoa Andrologia 46 2014 637 641
    • (2014) Andrologia , vol.46 , pp. 637-641
    • Banihani, S.1    Agarwal, A.2    Sharma, R.3
  • 37
    • 33646093473 scopus 로고    scopus 로고
    • Carnitine for the treatment of idiopathic asthenospermia: A randomized, double blind, placebo controlled trial
    • M. Sigman, S. Glass, J. Campagnone, and et al. Carnitine for the treatment of idiopathic asthenospermia: a randomized, double blind, placebo controlled trial Fertil Steril 85 2006 1409 1414
    • (2006) Fertil Steril , vol.85 , pp. 1409-1414
    • Sigman, M.1    Glass, S.2    Campagnone, J.3
  • 38
    • 34047151356 scopus 로고    scopus 로고
    • Effect of l-carnitine and/or l-acetyl-carnitine in nutrition treatment for male infertility: A systematic review
    • X. Zhou, F. Liu, and S. Zhai Effect of l-carnitine and/or l-acetyl-carnitine in nutrition treatment for male infertility: a systematic review Asia Pac J Clin Nutr 16 2007 383 390
    • (2007) Asia Pac J Clin Nutr , vol.16 , pp. 383-390
    • Zhou, X.1    Liu, F.2    Zhai, S.3
  • 39
    • 84862647334 scopus 로고    scopus 로고
    • Effects of l-carnitine on ejaculate parameters in males from infertile Couples
    • ShN. Galimov, D.S. Gromenko, É.F. Galimova, and et al. Effects of l-carnitine on ejaculate parameters in males from infertile Couples Urologia 1 2012 47 51
    • (2012) Urologia , vol.1 , pp. 47-51
    • Galimov ShN.1    Gromenko, D.S.2    Galimova, É.F.3
  • 40
    • 84872787672 scopus 로고    scopus 로고
    • Short-term medication of l-carnitine before intracytoplasmic sperm injection for infertile men with oligoasthenozoospermia
    • Z.M. Wu, X. Lu, Y.W. Wang, and et al. Short-term medication of l-carnitine before intracytoplasmic sperm injection for infertile men with oligoasthenozoospermia Zhonghua Nan Ke Xue 18 2012 253 256
    • (2012) Zhonghua Nan Ke Xue , vol.18 , pp. 253-256
    • Wu, Z.M.1    Lu, X.2    Wang, Y.W.3
  • 41
    • 84893469946 scopus 로고    scopus 로고
    • Effect of Coenzyme Q10 supplementation on antioxidant enzymes activity and oxidative stress of seminal plasma: A double-blind randomized clinical trial
    • A. Nadjarzadeh, F. Shidfar, N. Amirjannati, and et al. Effect of Coenzyme Q10 supplementation on antioxidant enzymes activity and oxidative stress of seminal plasma: a double-blind randomized clinical trial Andrologia 46 2014 177 183
    • (2014) Andrologia , vol.46 , pp. 177-183
    • Nadjarzadeh, A.1    Shidfar, F.2    Amirjannati, N.3
  • 42
    • 84864279309 scopus 로고    scopus 로고
    • The effect of coenzyme Q10 supplementation on partner pregnancy rate in infertile men with idiopathic oligoasthenoteratozoospermia: An open-label prospective study
    • M.R. Safarinejad The effect of coenzyme Q10 supplementation on partner pregnancy rate in infertile men with idiopathic oligoasthenoteratozoospermia: an open-label prospective study Int Urol Nephrol 44 2012 689 700
    • (2012) Int Urol Nephrol , vol.44 , pp. 689-700
    • Safarinejad, M.R.1
  • 43
    • 84863728173 scopus 로고    scopus 로고
    • Effects of the reduced form of coenzyme Q10 (ubiquinol) on semen parameters in men with idiopathic infertility: A double-blind, placebo controlled, randomized study
    • M.R. Safarinejad, S. Safarinejad, N. Shafiei, and et al. Effects of the reduced form of coenzyme Q10 (ubiquinol) on semen parameters in men with idiopathic infertility: a double-blind, placebo controlled, randomized study J Urol 188 2012 526 531
    • (2012) J Urol , vol.188 , pp. 526-531
    • Safarinejad, M.R.1    Safarinejad, S.2    Shafiei, N.3
  • 45
    • 84855507529 scopus 로고    scopus 로고
    • Coenzyme Q10 improves seminal oxidative defense but does not affect on semen parameters in idiopathic oligoasthenoteratozoospermia: A randomized double-blind, placebo controlled trial
    • A. Nadjarzadeh, M.R. Sadeghi, N. Amirjannati, and et al. Coenzyme Q10 improves seminal oxidative defense but does not affect on semen parameters in idiopathic oligoasthenoteratozoospermia: a randomized double-blind, placebo controlled trial J Endocrinol Invest 34 2011 e224 e228
    • (2011) J Endocrinol Invest , vol.34 , pp. e224-e228
    • Nadjarzadeh, A.1    Sadeghi, M.R.2    Amirjannati, N.3
  • 46
    • 84881523637 scopus 로고    scopus 로고
    • Protective effects of in vitro treatment with zinc, d-aspartate and Coenzyme Q10 on human sperm motility, lipid peroxidation and DNA fragmentation
    • R. Talevi, V. Barbato, I. Fiorentino, and et al. Protective effects of in vitro treatment with zinc, d-aspartate and Coenzyme Q10 on human sperm motility, lipid peroxidation and DNA fragmentation Reprod Biol Endocrinol 16 2013 81
    • (2013) Reprod Biol Endocrinol , vol.16 , pp. 81
    • Talevi, R.1    Barbato, V.2    Fiorentino, I.3
  • 47
    • 0033755597 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase in the rat testis: Evidence for potential roles in both normal function and inflammation-mediated infertility
    • M.K. O'Bryan, S. Schlatt, O. Gerdprasert, and et al. Inducible nitric oxide synthase in the rat testis: evidence for potential roles in both normal function and inflammation-mediated infertility Biol Reprod 63 2000 1285 1293
    • (2000) Biol Reprod , vol.63 , pp. 1285-1293
    • O'Bryan, M.K.1    Schlatt, S.2    Gerdprasert, O.3
  • 48
    • 0343091525 scopus 로고    scopus 로고
    • Seminal arginase activity in infertility
    • S. Elgün, M. Kaçmaz, I. Sen, and et al. Seminal arginase activity in infertility Urol Res 28 2000 20 23
    • (2000) Urol Res , vol.28 , pp. 20-23
    • Elgün, S.1    Kaçmaz, M.2    Sen, I.3
  • 49
    • 0141515692 scopus 로고    scopus 로고
    • Progressive motility increase caused by L-arginine and polyamines in sperm from patients with idiopathic and diabetic asthenozoospermia
    • M.E. Morales, G. Rico, C. Bravo, and et al. Progressive motility increase caused by L-arginine and polyamines in sperm from patients with idiopathic and diabetic asthenozoospermia Ginecol Obstet Mex 71 2003 297 303
    • (2003) Ginecol Obstet Mex , vol.71 , pp. 297-303
    • Morales, M.E.1    Rico, G.2    Bravo, C.3
  • 50
    • 0034936178 scopus 로고    scopus 로고
    • Nitric oxide synthase activity in human seminal plasma
    • A. Zini, M.K. O'Bryan, and P.N. Schlegel Nitric oxide synthase activity in human seminal plasma Urology 58 2001 85 89
    • (2001) Urology , vol.58 , pp. 85-89
    • Zini, A.1    O'Bryan, M.K.2    Schlegel, P.N.3
  • 51
    • 1242275295 scopus 로고    scopus 로고
    • Role of nitric oxide concentrations on human sperm motility
    • G. Balercia, S. Moretti, A. Vignini, and et al. Role of nitric oxide concentrations on human sperm motility J Androl 25 2004 245 249
    • (2004) J Androl , vol.25 , pp. 245-249
    • Balercia, G.1    Moretti, S.2    Vignini, A.3
  • 52
    • 0029016647 scopus 로고
    • The role of arginine, indomethacin and kallikrein in the treatment of oligoasthenospermia
    • S. Aydin, O. Inci, and B. Alagöl The role of arginine, indomethacin and kallikrein in the treatment of oligoasthenospermia Int Urol Nephrol 27 1995 199 202
    • (1995) Int Urol Nephrol , vol.27 , pp. 199-202
    • Aydin, S.1    Inci, O.2    Alagöl, B.3
  • 53
    • 38449106531 scopus 로고    scopus 로고
    • Sperm parameters in male idiopathic infertility after treatment with prelox
    • V. Nikolova, R. Stanislavov, I. Vatev, and et al. Sperm parameters in male idiopathic infertility after treatment with prelox Akush Ginekol (Sofiia) 46 2007 7 12
    • (2007) Akush Ginekol (Sofiia) , vol.46 , pp. 7-12
    • Nikolova, V.1    Stanislavov, R.2    Vatev, I.3
  • 54
    • 61449217851 scopus 로고    scopus 로고
    • Improvement of seminal parameters with Prelox: A randomized, double-blind, placebo-controlled, cross-over trial
    • R. Stanislavov, V. Nikolova, and P. Rohdewald Improvement of seminal parameters with Prelox: a randomized, double-blind, placebo-controlled, cross-over trial Phytother Res 23 2009 297 302
    • (2009) Phytother Res , vol.23 , pp. 297-302
    • Stanislavov, R.1    Nikolova, V.2    Rohdewald, P.3
  • 55
    • 0036865838 scopus 로고    scopus 로고
    • A new look at the medical management of infertility
    • F.M. Siddiq, and M. Sigman A new look at the medical management of infertility Urol Clin North Am 29 2002 949 963
    • (2002) Urol Clin North Am , vol.29 , pp. 949-963
    • Siddiq, F.M.1    Sigman, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.