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Volumn 64, Issue 1, 2016, Pages 14-24

Microarray to deep sequencing: transcriptome and miRNA profiling to elucidate molecular pathways in systemic lupus erythematosus

Author keywords

DNA methylation; Microarray; microRNA; RNA sequencing; Systemic lupus erythematosus

Indexed keywords

CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CX3CR1; CXCL2 CHEMOKINE; CXCL3 CHEMOKINE; INTERFERON; INTERLEUKIN 1; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; MICRORNA; TRANSCRIPTOME; CYTOKINE;

EID: 84955627567     PISSN: 0257277X     EISSN: 15590755     Source Type: Journal    
DOI: 10.1007/s12026-015-8672-y     Document Type: Review
Times cited : (25)

References (68)
  • 1
    • 14244250736 scopus 로고    scopus 로고
    • Autoantibody explosion in systemic lupus erythematosus: more than 100 different antibodies found in SLE patients
    • PID: 15505768
    • Sherer Y, Gorstein A, Fritzler MJ, Shoenfeld Y. Autoantibody explosion in systemic lupus erythematosus: more than 100 different antibodies found in SLE patients. Semin Arthritis Rheum. 2004;34:501–37.
    • (2004) Semin Arthritis Rheum , vol.34 , pp. 501-537
    • Sherer, Y.1    Gorstein, A.2    Fritzler, M.J.3    Shoenfeld, Y.4
  • 2
    • 84895896764 scopus 로고    scopus 로고
    • Diagnostic criteria for systemic lupus erythematosus: a critical review
    • PID: 24461385
    • Yu C, Gershwin ME, Chang C. Diagnostic criteria for systemic lupus erythematosus: a critical review. J Autoimmun. 2014;48–49:10–3.
    • (2014) J Autoimmun , vol.48-49 , pp. 10-13
    • Yu, C.1    Gershwin, M.E.2    Chang, C.3
  • 3
    • 0002738994 scopus 로고    scopus 로고
    • The epidemiology of systemic lupus erythematosus
    • Wallace DJ, Hahn BH, (eds), Williams and Wilkins, Baltimore
    • Hochberg MC. The epidemiology of systemic lupus erythematosus. In: Wallace DJ, Hahn BH, editors. Dubois’ lupus erythematosus. 7th ed. Baltimore: Williams and Wilkins; 1997. p. 49–65.
    • (1997) Dubois’ lupus erythematosus , pp. 49-65
    • Hochberg, M.C.1
  • 4
    • 33744822178 scopus 로고    scopus 로고
    • Epidemiology of systemic lupus erythematosus: a comparison of worldwide disease burden
    • PID: 16761508
    • Danchenko N, Satia JA, Anthony MS. Epidemiology of systemic lupus erythematosus: a comparison of worldwide disease burden. Lupus. 2006;15:308–18.
    • (2006) Lupus , vol.15 , pp. 308-318
    • Danchenko, N.1    Satia, J.A.2    Anthony, M.S.3
  • 5
    • 0031884870 scopus 로고    scopus 로고
    • High levels of circulating early apoptotic peripheral blood mononuclear cells in systemic lupus erythematosus
    • PID: 9541096
    • Perniok A, Wedekind F, Herrmann M, Specker C, Schneider M. High levels of circulating early apoptotic peripheral blood mononuclear cells in systemic lupus erythematosus. Lupus. 1998;7:113–8.
    • (1998) Lupus , vol.7 , pp. 113-118
    • Perniok, A.1    Wedekind, F.2    Herrmann, M.3    Specker, C.4    Schneider, M.5
  • 7
    • 0142072318 scopus 로고    scopus 로고
    • Increased apoptotic neutrophils and macrophages and impaired macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus
    • PID: 14558095
    • Ren Y, Tang J, Mok MY, Chan AW, Wu A, Lau CS. Increased apoptotic neutrophils and macrophages and impaired macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus. Arthritis Rheum. 2003;48:2888–97.
    • (2003) Arthritis Rheum , vol.48 , pp. 2888-2897
    • Ren, Y.1    Tang, J.2    Mok, M.Y.3    Chan, A.W.4    Wu, A.5    Lau, C.S.6
  • 9
    • 84874284576 scopus 로고    scopus 로고
    • NETs: the missing link between cell death and systemic autoimmune diseases?
    • PID: 23335928
    • Darrah E, Andrade F. NETs: the missing link between cell death and systemic autoimmune diseases? Front Immunol. 2013;3:428.
    • (2013) Front Immunol , vol.3 , pp. 428
    • Darrah, E.1    Andrade, F.2
  • 10
    • 0035525528 scopus 로고    scopus 로고
    • From T to B and back again: positive feedback in systemic autoimmune disease
    • PID: 11905822
    • Shlomchik MJ, Craft JE, Mamula MJ. From T to B and back again: positive feedback in systemic autoimmune disease. Nat Rev Immunol. 2001;1:147–53.
    • (2001) Nat Rev Immunol , vol.1 , pp. 147-153
    • Shlomchik, M.J.1    Craft, J.E.2    Mamula, M.J.3
  • 11
    • 0036201362 scopus 로고    scopus 로고
    • Expression of cytokine- and chemokine-related genes in peripheral blood mononuclear cells from lupus patients by cDNA array
    • PID: 11890715
    • Rus V, Atamas SP, Shustova V, Luzina IG, Selaru F, Magder LS, Via CS. Expression of cytokine- and chemokine-related genes in peripheral blood mononuclear cells from lupus patients by cDNA array. Clin Immunol. 2002;102:283–90.
    • (2002) Clin Immunol , vol.102 , pp. 283-290
    • Rus, V.1    Atamas, S.P.2    Shustova, V.3    Luzina, I.G.4    Selaru, F.5    Magder, L.S.6    Via, C.S.7
  • 12
    • 0141986842 scopus 로고    scopus 로고
    • Analysis of gene expression profiles in human systemic lupus erythematosus using oligonucleotide microarray
    • PID: 12700592
    • Han GM, Chen SL, Shen N, Ye S, Bao CD, Gu YY. Analysis of gene expression profiles in human systemic lupus erythematosus using oligonucleotide microarray. Genes Immun. 2003;4:177–86.
    • (2003) Genes Immun , vol.4 , pp. 177-186
    • Han, G.M.1    Chen, S.L.2    Shen, N.3    Ye, S.4    Bao, C.D.5    Gu, Y.Y.6
  • 14
    • 1542542349 scopus 로고    scopus 로고
    • Design peptide scaffolds for regenerative medicine
    • PID: 12903718
    • Zhang S, Semino CE. Design peptide scaffolds for regenerative medicine. Adv Exp Med Biol. 2003;534:147–63.
    • (2003) Adv Exp Med Biol , vol.534 , pp. 147-163
    • Zhang, S.1    Semino, C.E.2
  • 15
    • 1642374097 scopus 로고    scopus 로고
    • Specificity of microRNA target selection in translational repression
    • PID: 15014042
    • Doench JG, Sharp PA. Specificity of microRNA target selection in translational repression. Genes Dev. 2004;18:504–11.
    • (2004) Genes Dev , vol.18 , pp. 504-511
    • Doench, J.G.1    Sharp, P.A.2
  • 16
    • 84900415568 scopus 로고    scopus 로고
    • The SLE transcriptome exhibits evidence of chronic endotoxin exposure and has widespread dysregulation of non-coding and coding RNAs
    • PID: 24796678
    • Shi L, Zhang Z, Yu AM, Wang W, Wei Z, Akhter E, Maurer K, Costa Reis P, Song L, Petri M, Sullivan KE. The SLE transcriptome exhibits evidence of chronic endotoxin exposure and has widespread dysregulation of non-coding and coding RNAs. PLoS ONE. 2014;9:e93846.
    • (2014) PLoS ONE , vol.9 , pp. e93846
    • Shi, L.1    Zhang, Z.2    Yu, A.M.3    Wang, W.4    Wei, Z.5    Akhter, E.6    Maurer, K.7    Costa Reis, P.8    Song, L.9    Petri, M.10    Sullivan, K.E.11
  • 20
    • 77956905671 scopus 로고    scopus 로고
    • Platelet transcriptional profile and protein expression in patients with systemic lupus erythematosus: up-regulation of the type I interferon system is strongly associated with vascular disease
    • PID: 20538795
    • Lood C, Amisten S, Gullstrand B, Jönsen A, Allhorn M, Truedsson L, Sturfelt G, Erlinge D, Bengtsson AA. Platelet transcriptional profile and protein expression in patients with systemic lupus erythematosus: up-regulation of the type I interferon system is strongly associated with vascular disease. Blood. 2010;116:1951–7.
    • (2010) Blood , vol.116 , pp. 1951-1957
    • Lood, C.1    Amisten, S.2    Gullstrand, B.3    Jönsen, A.4    Allhorn, M.5    Truedsson, L.6    Sturfelt, G.7    Erlinge, D.8    Bengtsson, A.A.9
  • 22
    • 47949089923 scopus 로고    scopus 로고
    • Association of a gene expression profile from whole blood with disease activity in systemic lupus erythaematosus
    • PID: 18063674
    • Nikpour M, Dempsey AA, Urowitz MB, Gladman DD, Barnes DA. Association of a gene expression profile from whole blood with disease activity in systemic lupus erythaematosus. Ann Rheum Dis. 2008;67:1069–75.
    • (2008) Ann Rheum Dis , vol.67 , pp. 1069-1075
    • Nikpour, M.1    Dempsey, A.A.2    Urowitz, M.B.3    Gladman, D.D.4    Barnes, D.A.5
  • 24
    • 79957541792 scopus 로고    scopus 로고
    • Meta-analysis of microarray data using a pathway-based approach identifies a 37-gene expression signature for systemic lupus erythematosus in human peripheral blood mononuclear cells
    • PID: 21624134
    • Arasappan D, Tong W, Mummaneni P, Fang H, Amur S. Meta-analysis of microarray data using a pathway-based approach identifies a 37-gene expression signature for systemic lupus erythematosus in human peripheral blood mononuclear cells. BMC Med. 2011;9:65.
    • (2011) BMC Med , vol.9 , pp. 65
    • Arasappan, D.1    Tong, W.2    Mummaneni, P.3    Fang, H.4    Amur, S.5
  • 25
    • 0034533825 scopus 로고    scopus 로고
    • Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies
    • PID: 11199920
    • Bengtsson AA, Sturfelt G, Truedsson L, Blomberg J, Alm G, Vallin H, Ronnblom L. Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies. Lupus. 2000;9:664–71.
    • (2000) Lupus , vol.9 , pp. 664-671
    • Bengtsson, A.A.1    Sturfelt, G.2    Truedsson, L.3    Blomberg, J.4    Alm, G.5    Vallin, H.6    Ronnblom, L.7
  • 26
    • 0038639795 scopus 로고    scopus 로고
    • Systemic lupus erythematosus and the type I interferon system
    • PID: 12718746
    • Ronnblom L, Alm GV. Systemic lupus erythematosus and the type I interferon system. Arthritis Res Ther. 2003;5:68–75.
    • (2003) Arthritis Res Ther , vol.5 , pp. 68-75
    • Ronnblom, L.1    Alm, G.V.2
  • 28
    • 4644343950 scopus 로고    scopus 로고
    • Autoimmunity gene expression portrait: specific signature that intersects or differentiates between multiple sclerosis and systemic lupus erythematosus
    • PID: 15373920
    • Mandel M, Gurevich M, Pauzner R, Kaminski N, Achiron A. Autoimmunity gene expression portrait: specific signature that intersects or differentiates between multiple sclerosis and systemic lupus erythematosus. Clin Exp Immunol. 2004;138:164–70.
    • (2004) Clin Exp Immunol , vol.138 , pp. 164-170
    • Mandel, M.1    Gurevich, M.2    Pauzner, R.3    Kaminski, N.4    Achiron, A.5
  • 30
    • 4043168531 scopus 로고    scopus 로고
    • Gene expression profiling in peripheral blood mononuclear cells from lupus patients with active and inactive disease
    • PID: 15308115
    • Rus V, Chen H, Zernetkina V, Magder LS, Mathai S, Hochberg MC, Via CS. Gene expression profiling in peripheral blood mononuclear cells from lupus patients with active and inactive disease. Clin Immunol. 2004;112:231–4.
    • (2004) Clin Immunol , vol.112 , pp. 231-234
    • Rus, V.1    Chen, H.2    Zernetkina, V.3    Magder, L.S.4    Mathai, S.5    Hochberg, M.C.6    Via, C.S.7
  • 35
    • 39049174107 scopus 로고    scopus 로고
    • Gene expression profiling of peripheral leukocytes from patients with systemic lupus erythematosus using oligonucleotide DNA microarray
    • PID: 16109543
    • Wu YS, Fan RQ, Chen DC, Xuan GW. Gene expression profiling of peripheral leukocytes from patients with systemic lupus erythematosus using oligonucleotide DNA microarray. Di Yi Jun Yi Da Xue Xue Bao. 2005;25:929–34.
    • (2005) Di Yi Jun Yi Da Xue Xue Bao , vol.25 , pp. 929-934
    • Wu, Y.S.1    Fan, R.Q.2    Chen, D.C.3    Xuan, G.W.4
  • 37
    • 84880854544 scopus 로고    scopus 로고
    • Aberrant B cell selection and activation in systemic lupus erythematosus
    • PID: 23768157
    • Kil LP, Hendriks RW. Aberrant B cell selection and activation in systemic lupus erythematosus. Int Rev Immunol. 2013;32:445–70.
    • (2013) Int Rev Immunol , vol.32 , pp. 445-470
    • Kil, L.P.1    Hendriks, R.W.2
  • 38
    • 66149083275 scopus 로고    scopus 로고
    • Review of recent genome-wide association scans in lupus
    • PID: 19493061
    • Graham RR, Hom G, Ortmann W, Behrens TW. Review of recent genome-wide association scans in lupus. J Intern Med. 2009;265:680–8.
    • (2009) J Intern Med , vol.265 , pp. 680-688
    • Graham, R.R.1    Hom, G.2    Ortmann, W.3    Behrens, T.W.4
  • 39
    • 70350629871 scopus 로고    scopus 로고
    • Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus
    • PID: 19838193
    • Han JW, Zheng HF, Cui Y, Sun LD, Ye DQ, et al. Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. Nat Genet. 2009;41:1234–7.
    • (2009) Nat Genet , vol.41 , pp. 1234-1237
    • Han, J.W.1    Zheng, H.F.2    Cui, Y.3    Sun, L.D.4    Ye, D.Q.5
  • 40
    • 77649206245 scopus 로고    scopus 로고
    • Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus
    • PID: 20169177
    • Yang W, Shen N, Ye D-Q, Liu Q, Zhang Y, et al. Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus. PLoS Genet. 2010;6:e1000841.
    • (2010) PLoS Genet , vol.6 , pp. e1000841
    • Yang, W.1    Shen, N.2    Ye, D.-Q.3    Liu, Q.4    Zhang, Y.5
  • 41
    • 84865473936 scopus 로고    scopus 로고
    • Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways
    • PID: 22753952
    • Vaughn SE, Kottyan LC, Munroe ME, Harley JB. Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways. J Leukoc Biol. 2012;92:577–91.
    • (2012) J Leukoc Biol , vol.92 , pp. 577-591
    • Vaughn, S.E.1    Kottyan, L.C.2    Munroe, M.E.3    Harley, J.B.4
  • 42
    • 84866720077 scopus 로고    scopus 로고
    • Molecular characterization of circulating plasma cells in patients with active systemic lupus erythematosus
    • PID: 23028528
    • Lugar PL, Love C, Grammer AC, Dave SS, Lipsky PE. Molecular characterization of circulating plasma cells in patients with active systemic lupus erythematosus. PLoS ONE. 2012;7:e44362.
    • (2012) PLoS ONE , vol.7 , pp. e44362
    • Lugar, P.L.1    Love, C.2    Grammer, A.C.3    Dave, S.S.4    Lipsky, P.E.5
  • 43
    • 26444577831 scopus 로고    scopus 로고
    • Metallothionein mediates leukocyte chemotaxis
    • PID: 16164753
    • Yin X, Knecht DA, Lynes MA. Metallothionein mediates leukocyte chemotaxis. BMC Immunol. 2005;6:21.
    • (2005) BMC Immunol , vol.6 , pp. 21
    • Yin, X.1    Knecht, D.A.2    Lynes, M.A.3
  • 45
    • 0023216891 scopus 로고
    • CpG islands in vertebrate genomes
    • PID: 3656447
    • Gardiner-Garden M, Frommer M. CpG islands in vertebrate genomes. J Mol Biol. 1987;196:261–82.
    • (1987) J Mol Biol , vol.196 , pp. 261-282
    • Gardiner-Garden, M.1    Frommer, M.2
  • 46
    • 33744936286 scopus 로고    scopus 로고
    • The epigenetic face of systemic lupus erythematosus
    • PID: 16751355
    • Ballestar E, Esteller M, Richardson BC. The epigenetic face of systemic lupus erythematosus. J Immunol. 2006;176:7143–7.
    • (2006) J Immunol , vol.176 , pp. 7143-7147
    • Ballestar, E.1    Esteller, M.2    Richardson, B.C.3
  • 47
    • 2642556447 scopus 로고    scopus 로고
    • Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors
    • PID: 15188362
    • Oelke K, Lu Q, Richardson D, Wu A, Deng C, Hanash S, Richardson B. Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors. Arthritis Rheum. 2004;50:1850–60.
    • (2004) Arthritis Rheum , vol.50 , pp. 1850-1860
    • Oelke, K.1    Lu, Q.2    Richardson, D.3    Wu, A.4    Deng, C.5    Hanash, S.6    Richardson, B.7
  • 49
    • 78650626621 scopus 로고    scopus 로고
    • RFX1 regulates CD70 and CD11a expression in lupus T cells by recruiting the histone methyltransferase SUV39H1
    • PID: 21192791
    • Zhao M, Wu X, Zhang Q, Luo S, Liang G, Su Y, Tan Y, Lu Q. RFX1 regulates CD70 and CD11a expression in lupus T cells by recruiting the histone methyltransferase SUV39H1. Arthritis Res Ther. 2010;12:R227.
    • (2010) Arthritis Res Ther , vol.12 , pp. R227
    • Zhao, M.1    Wu, X.2    Zhang, Q.3    Luo, S.4    Liang, G.5    Su, Y.6    Tan, Y.7    Lu, Q.8
  • 50
    • 79957550675 scopus 로고    scopus 로고
    • Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus
    • PID: 21436623
    • Jeffries MA, Dozmorov M, Tang Y, Merrill JT, Wren JD, Sawalha AH. Genome-wide DNA methylation patterns in CD4+ T cells from patients with systemic lupus erythematosus. Epigenetics. 2011;6:593–601.
    • (2011) Epigenetics , vol.6 , pp. 593-601
    • Jeffries, M.A.1    Dozmorov, M.2    Tang, Y.3    Merrill, J.T.4    Wren, J.D.5    Sawalha, A.H.6
  • 51
    • 34249690659 scopus 로고    scopus 로고
    • Transcript overexpression of the MBD2 and MBD4 genes in CD4+ T cells from systemic lupus erythematosus patients
    • PID: 17360956
    • Balada E, Ordi-Ros J, Serrano-Acedo S, Martinez-Lostao L, Vilardell-Tarrés M. Transcript overexpression of the MBD2 and MBD4 genes in CD4+ T cells from systemic lupus erythematosus patients. J Leukoc Biol. 2007;81:1609–16.
    • (2007) J Leukoc Biol , vol.81 , pp. 1609-1616
    • Balada, E.1    Ordi-Ros, J.2    Serrano-Acedo, S.3    Martinez-Lostao, L.4    Vilardell-Tarrés, M.5
  • 52
    • 79956191491 scopus 로고    scopus 로고
    • Analysis of associations between the patterns of global DNA hypomethylation and expression of DNA methyltransferase in patients with systemic lupus erythematosus
    • PID: 21595664
    • Zhu X, Liang J, Li F, Yang Y, Xiang L, Xu J. Analysis of associations between the patterns of global DNA hypomethylation and expression of DNA methyltransferase in patients with systemic lupus erythematosus. Int J Dermatol. 2011;50:697–704.
    • (2011) Int J Dermatol , vol.50 , pp. 697-704
    • Zhu, X.1    Liang, J.2    Li, F.3    Yang, Y.4    Xiang, L.5    Xu, J.6
  • 53
    • 37848999684 scopus 로고    scopus 로고
    • Hypomethylation of interleukin-4 and -6 promoters in T cells from systemic lupus erythematosus patients
    • PID: 18158872
    • Mi XB, Zeng FQ. Hypomethylation of interleukin-4 and -6 promoters in T cells from systemic lupus erythematosus patients. Acta Pharmacol Sin. 2008;29:105–12.
    • (2008) Acta Pharmacol Sin , vol.29 , pp. 105-112
    • Mi, X.B.1    Zeng, F.Q.2
  • 54
    • 84884634092 scopus 로고    scopus 로고
    • Genome-wide DNA methylation analysis of systemic lupus erythematosus reveals persistent hypomethylation of interferon genes and compositional changes to CD4+ T-cell populations
    • PID: 23950730
    • Absher DM, Li X, Waite LL, Gibson A, Roberts K, Edberg J, Chatham WW, Kimberly RP. Genome-wide DNA methylation analysis of systemic lupus erythematosus reveals persistent hypomethylation of interferon genes and compositional changes to CD4+ T-cell populations. PLoS Genet. 2013;9:e1003678.
    • (2013) PLoS Genet , vol.9 , pp. e1003678
    • Absher, D.M.1    Li, X.2    Waite, L.L.3    Gibson, A.4    Roberts, K.5    Edberg, J.6    Chatham, W.W.7    Kimberly, R.P.8
  • 55
    • 77649340053 scopus 로고    scopus 로고
    • Global H4 acetylation analysis by ChIP-chip in systemic lupus erythematosus monocytes
    • PID: 19710693
    • Zhang Z, Song L, Maurer K, Petri MA, Sullivan KE. Global H4 acetylation analysis by ChIP-chip in systemic lupus erythematosus monocytes. Genes Immun. 2010;11:124–33.
    • (2010) Genes Immun , vol.11 , pp. 124-133
    • Zhang, Z.1    Song, L.2    Maurer, K.3    Petri, M.A.4    Sullivan, K.E.5
  • 57
    • 37849031502 scopus 로고    scopus 로고
    • Microarray analysis of microRNA expression in peripheral blood cells of systemic lupus erythematosus patients
    • PID: 18042587
    • Dai Y, Huang YS, Tang M, Lv TY, Hu CX, Tan YH, Xu ZM, Yin YB. Microarray analysis of microRNA expression in peripheral blood cells of systemic lupus erythematosus patients. Lupus. 2007;16:939–46.
    • (2007) Lupus , vol.16 , pp. 939-946
    • Dai, Y.1    Huang, Y.S.2    Tang, M.3    Lv, T.Y.4    Hu, C.X.5    Tan, Y.H.6    Xu, Z.M.7    Yin, Y.B.8
  • 58
    • 65249138193 scopus 로고    scopus 로고
    • MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins
    • PID: 19333922
    • Tang Y, Luo X, Cui H, Ni X, Yuan M, Guo Y, Huang X, Zhou H, de Vries N, Tak PP, Chen S, Shen N. MicroRNA-146A contributes to abnormal activation of the type I interferon pathway in human lupus by targeting the key signaling proteins. Arthritis Rheum. 2009;60:1065–75.
    • (2009) Arthritis Rheum , vol.60 , pp. 1065-1075
    • Tang, Y.1    Luo, X.2    Cui, H.3    Ni, X.4    Yuan, M.5    Guo, Y.6    Huang, X.7    Zhou, H.8    de Vries, N.9    Tak, P.P.10    Chen, S.11    Shen, N.12
  • 59
    • 79959784552 scopus 로고    scopus 로고
    • Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression
    • PID: 21602271
    • Stagakis E, Bertsias G, Verginis P, Nakou M, Hatziapostolou M, Kritikos H, Iliopoulos D, Boumpas DT. Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression. Ann Rheum Dis. 2011;70:1496–506.
    • (2011) Ann Rheum Dis , vol.70 , pp. 1496-1506
    • Stagakis, E.1    Bertsias, G.2    Verginis, P.3    Nakou, M.4    Hatziapostolou, M.5    Kritikos, H.6    Iliopoulos, D.7    Boumpas, D.T.8
  • 60
    • 84904057971 scopus 로고    scopus 로고
    • MicroRNA expression profiles of peripheral blood mononuclear cells in patients with systemic lupus erythematosus
    • PID: 24657071
    • Liu D, Zhao H, Zhao S, Wang X. MicroRNA expression profiles of peripheral blood mononuclear cells in patients with systemic lupus erythematosus. Acta Histochem. 2014;116:891–7.
    • (2014) Acta Histochem , vol.116 , pp. 891-897
    • Liu, D.1    Zhao, H.2    Zhao, S.3    Wang, X.4
  • 61
    • 84901452242 scopus 로고    scopus 로고
    • Differential microRNA profile and post-transcriptional regulation exist in systemic lupus erythematosus patients with distinct autoantibody specificities
    • PID: 24659206
    • Chauhan SK, Singh VV, Rai R, Rai M, Rai G. Differential microRNA profile and post-transcriptional regulation exist in systemic lupus erythematosus patients with distinct autoantibody specificities. J Clin Immunol. 2014;34:491–503.
    • (2014) J Clin Immunol , vol.34 , pp. 491-503
    • Chauhan, S.K.1    Singh, V.V.2    Rai, R.3    Rai, M.4    Rai, G.5
  • 62
    • 79955569628 scopus 로고    scopus 로고
    • MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1
    • PID: 21538319
    • Zhao S, Wang Y, Liang Y, Zhao M, Long H, Ding S, Yin H, Lu Q. MicroRNA-126 regulates DNA methylation in CD4+ T cells and contributes to systemic lupus erythematosus by targeting DNA methyltransferase 1. Arthritis Rheum. 2011;63:1376–86.
    • (2011) Arthritis Rheum , vol.63 , pp. 1376-1386
    • Zhao, S.1    Wang, Y.2    Liang, Y.3    Zhao, M.4    Long, H.5    Ding, S.6    Yin, H.7    Lu, Q.8
  • 63
    • 84870899591 scopus 로고    scopus 로고
    • MicroRNA-29b contributes to DNA hypomethylation of CD4+ T cells in systemic lupus erythematosus by indirectly targeting DNA methyltransferase 1
    • PID: 23142053
    • Qin H, Zhu X, Liang J, Wu J, Yang Y, Wang S, Shi W, Xu J. MicroRNA-29b contributes to DNA hypomethylation of CD4+ T cells in systemic lupus erythematosus by indirectly targeting DNA methyltransferase 1. J Dermatol Sci. 2013;69:61–7.
    • (2013) J Dermatol Sci , vol.69 , pp. 61-67
    • Qin, H.1    Zhu, X.2    Liang, J.3    Wu, J.4    Yang, Y.5    Wang, S.6    Shi, W.7    Xu, J.8
  • 67
    • 84899495767 scopus 로고    scopus 로고
    • Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling
    • PID: 24686847
    • Rice GI, del Toro Duany Y, Jenkinson EM, Forte GM, Anderson BH, Ariaudo G, et al. Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling. Nat Genet. 2014;46:503–9.
    • (2014) Nat Genet , vol.46 , pp. 503-509
    • Rice, G.I.1    del Toro, D.Y.2    Jenkinson, E.M.3    Forte, G.M.4    Anderson, B.H.5    Ariaudo, G.6


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