Gastric Cancer Screening by Combined Assay for Serum Anti-Helicobacter pylori IgG Antibody and Serum Pepsinogen Levels-The ABC Method

Digestion

Volumn 93, Issue 1, 2016, Pages 13-18

  Yamaguchi, Yasuharu ^a   Nagata, Yasuhiko ^a   Hiratsuka, Ryuuta ^a   Kawase, Yoshihiko ^a   Tominaga, Tatsurou ^a   Takeuchi, Shunji ^a   Sakagami, Shinya ^a   Ishida, Shusei ^a  

^a Yamaguchi Internal Medicine   (Japan)

Author keywords

ABC method; Cancer screening; Gastric cancer; Helicobacter pylori; Pepsinogen

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY; PEPSINOGEN; BACTERIUM ANTIBODY; IMMUNOGLOBULIN G;

ADENOMA; ADVANCED CANCER; ANTIBODY BLOOD LEVEL; BLOOD EXAMINATION; CANCER RISK; CANCER SCREENING; CONFERENCE PAPER; DUODENUM CANCER; ENDOSCOPIC SURGERY; ENDOSCOPY; ESOPHAGUS CANCER; GASTRIC ADENOMA; HUMAN; MARGINAL ZONE LYMPHOMA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RADIODIAGNOSIS; STOMACH CANCER; BLOOD; CARCINOMA; EARLY CANCER DIAGNOSIS; GASTRITIS, ATROPHIC; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; IMMUNOLOGY; STOMACH NEOPLASMS;

ANTIBODIES, BACTERIAL; CARCINOMA; EARLY DETECTION OF CANCER; GASTRITIS, ATROPHIC; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNOGLOBULIN G; PEPSINOGEN A; STOMACH NEOPLASMS;

EID: 84955616296     PISSN: 00122823     EISSN: 14219867     Source Type: Journal    
DOI: 10.1159/000441742     Document Type: Conference Paper

References (26)

1. Asaka M, Kato M, Takahashi S, Fukuda Y, Sugiyama T, Ota H, Uemura N, Murakami K, Satoh K, Sugano K: Guidelines for the management of Helicobacter pylori infection in Japan: 2009 revised edition. Helicobacter 2010;15:1-20.
2. Hatakeyama M: Oncogenic mechanisms of the Helicobacter pylori CagA protein. Nat Rev Cancer 2004;4:688-694.
3. Nomura A, Stemmermann GN, Chyou PH, Kato I, Perez-Perez GI, Blaser MJ: Helicobacter pylori infection and gastric carcinoma among Japanese Americans in Hawaii. N Engl J Med 1991;325:1132-1136.
4. International Agency for Research on Cancer: Schistosomiasis, liver flukes and Helicobacter pylori. IARC Monogr Eval Carcinog Risks Hum 1994;61:177-240.
5. Uemura N, Okamoto S, Yamamoto S, Matsumura N, Yamaguchi S, Yamakido M, Taniyama K, Sasaki N, Schlemper RJ: Helicobacter pylori infection and the development of gastric cancer. N Engl J Med 2001;345:784-789.
6. Watabe H, Mitsushima T, Yamaji Y, Okamoto M, Wada R, Kokubo T, Doi H, Yoshida H, Kawabe T, Omata M: Predicting the development of gastric cancer from combining Helicobacter pylori antibodies and serum pepsinogen status: a prospective endoscopic cohort study. Gut 2005;54:764-768.
7. Fukase K, Kato M, Kikuchi S, Inoue K, Uemura N, Okamoto S, Terao S, Amagai K, Hayashi S, Asaka M: Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial. Lancet 2008;372:392-397.
8. Mizuno S, Miki I, Ishida T, Yoshida M, Onoyama M, Azuma T, Habu Y, Inokuchi H, Ozasa K, Miki K, Watanabe Y: Prescreening of a high-risk group for gastric cancer by serologically determined Helicobacter pylori infection and atrophic gastritis. Dig Dis Sci 2010;55:3132-3137.
9. Ichinose M, Miki K, Furihata C, Kageyama T, Hayashi R, Niwa H, Oka H, Matsushima T, Takahashi K: Radioimmunoassay of serum group I and group II pepsinogens in normal controls and patients with various disorders. Clin Chim Acta 1982;126:183-191.
10. Samloff IM, Varis K, Ihamaki T, Siurala M, Rotter JI: Relationships among serum pepsinogen I, serum pepsinogen II, and gastric mucosal histology. A study in relatives of patients with pernicious anemia. Gastroenterology 1982;83:204-209.
11. Miki K, Ichinose M, Furihata C, Niwa H, Oka H, Oda T, Matsushima T: Potential peptic activity of pepsinogen of human gastroduodenal mucosa determined by fluorescent microassay method using succinyl albumin. Clin Chim Acta 1982;121:337-344.
12. Miki K, Ichinose M, Ishikawa KB, Yahagi N, Matsushima M, Kakei N, Tsukada S, Kido M, Ishihama S, Shimizu Y, et al. Clinical application of serum pepsinogen I and II levels for mass screening to detect gastric cancer. Jpn J Cancer Res 1993;84:1086-1090.
13. Miki K, Ichinose M, Kakei N, Yahagi N, Matsushima M, Tsukada S, Ishihama S, Shimizu Y, Suzuki T, Kurokawa K, Takahashi K: The clinical application of the serum pepsinogen I and II levels as mass screening method for gastric cancer; in Takahashi K (ed): Aspartic Proteinases: Structure, Function, Biology and Biomedical Implications. New York, Plenum Press, 1995, pp 139-143.
14. Watanabe Y, Kurata JH, Mizuno S, Mukai M, Inokuchi H, Miki K, Ozasa K, Kawai K: Helicobacter pylori infection and gastric cancer. A nested case-control study in a rural area of Japan. Dig Dis Sci 1997;42:1383-1387.
15. Ohata H, Kitauchi S, Yoshimura N, Mugitani K, Iwane M, Nakamura H, Yoshikawa A, Yanaoka K, Arii K, Tamai H, Shimizu Y, Takeshita T, Mohara O, Ichinose M: Progression of chronic atrophic gastritis associated with Helicobacter pylori infection increases risk of gastric cancer. Int J Cancer 2004;109:138-143.
16. Yoshida T, Kato J, Inoue I, Yoshimura N, Deguchi H, Mukoubayashi C, Oka M, Watanabe M, Enomoto S, Niwa T, Maekita T, Iguchi M, Tamai H, Utsunomiya H, Yamamichi N, Fujishiro M, Iwane M, Takeshita T, Ushijima T, Ichinose M: Cancer development based on chronic active gastritis and resulting gastric atrophy as assessed by serum levels of pepsinogen and Helicobacter pylori antibody titer. Int J Cancer 2014;134:1445-1457.
17. Sasazuki S, Inoue M, Iwasaki M, Otani T, Yamamoto S, Ikeda S, Hanaoka T, Tsugane S; Japan Public Health Center Study Group: Effect of Helicobacter pylori infection combined with CagA and pepsinogen status on gastric cancer development among Japanese men and women: a nested case-control study. Cancer Epidemiol Biomarkers Prev 2006;15:1341-1347.
18. Yanaoka K, Oka M, Mukoubayashi C, Yoshimura N, Enomoto S, Iguchi M, Magari H, Utsunomiya H, Tamai H, Arii K, Ohata H, Fujishiro M, Takeshita T, Mohara O, Ichinose M: Cancer high-risk subjects identified by serum pepsinogen tests: outcomes after 10-year follow-up in asymptomatic middle-aged males. Cancer Epidemiol Biomarkers Prev 2008;17:838-845.
19. Watanabe M, Kato J, Inoue I, Yoshimura N, Yoshida T, Mukoubayashi C, Deguchi H, Enomoto S, Ueda K, Maekita T, Iguchi M, Tamai H, Utsunomiya H, Yamamichi N, Fujishiro M, Iwane M, Tekeshita T, Mohara O, Ushijima T, Ichinose M: Development of gastric cancer in nonatrophic stomach with highly active inflammation identified by serum levels of pepsinogen and Helicobacter pylori antibody together with endoscopic rugal hyperplastic gastritis. Int J Cancer 2012;131:2632-2642.
20. Masuyama H, Yoshitake N, Sasai T, Nakamura T, Masuyama A, Zuiki T, Kurashina K, Mieda M, Sunada K, Yamamoto H, Togashi K, Terano A, Hiraishi H: Relationship between the degree of endoscopic atrophy of the gastric mucosa and carcinogenic risk. Digestion 2015;91:30-36.
21. Miki K: Gastric cancer screening by combined assay for serum anti-Helicobacter pylori IgG antibody and serum pepsinogen levels-'ABC method'. Proc Jpn Acad Ser B Phys Biol Sci 2011;87:405-414.
22. Hisamichi S: Screening for gastric cancer. World J Surg 1989;13:31-37.
23. Bureau of Social Welfare and Public Health, Tokyo Metropolitan Government. http://www.fukushihoken.metro.tokyo.jp/kensui/gan/toukei/data/kako.html (in Japanese).
24. Nagata Y, Yamaguchi Y, Hiratsuka R, Tanaka U, Takahara T, Hirata K, Kawase Y, Tominaga T, Takeuchi S, Moritani M, Sakagami S, Ishida S: The efficacy of new gastric cancer screening, the ABC method, in Nishitokyo city. J Tokyo Med Assoc 2014;67:60-68.
25. Terasawa T, Nishida H, Kato K, Miyashiro I, Yoshikawa T, Takaku R, Hamashima C: Prediction of gastric cancer development by serum pepsinogen test and Helicobacter pylori seropositivity in Eastern Asians: a systematic review and meta-analysis. PLoS One 2014;9:e109783.
26. Gotoda T, Ishikawa H, Ohnishi H, Sugano K, Kusano C, Yokoi C, Matsuyama Y, Moriyasu F: Randomized controlled trial comparing gastric cancer screening by gastrointestinal X-ray with serology for Helicobacter pylori and pepsinogens followed by gastrointestinal endoscopy. Gastric Cancer 2015;18:605-611.