Elevation of IL-9 in extreme patch test reactions suggests it is an inflammatory mediator in allergic contact dermatitis

Dermatitis

Volumn 27, Issue 1, 2016, Pages 35-36

  Gutin, Liat ^a   Tammaro, Antonella ^a,b   Fishelevich, Rita ^a   Gaspari, Anthony A ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 9; NICKEL; PHENYLENEDIAMINE; AUTACOID;

BLISTER FLUID; CONTACT ALLERGY; HUMAN; IRRITANT DERMATITIS; LETTER; NONHUMAN; PATCH TEST; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SKIN ALLERGY; SKIN BIOPSY; TH9 CELL; ANIMAL; GENETICS; IMMUNOLOGY; MOUSE;

ANIMALS; DERMATITIS, ALLERGIC CONTACT; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-9; MICE; NICKEL; PATCH TESTS;

EID: 84955598149     PISSN: 17103568     EISSN: 21625220     Source Type: Journal    
DOI: 10.1097/DER.0000000000000159     Document Type: Letter

References (3)

1. Dardalhon V, Awasthi A, Kwon H, IL-4 inhibits TGF-beta-induced Foxp3+ T cells and together with TGF-beta, generates IL-9+ IL-10+ Foxp3(-) effector T cells. Nat Immunol 2008; 9: 1347-1355
2. Veldhoen M, Uyttenhove C, van Snick J, Transforming growth factor-beta "reprograms" the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat Immunol 2008; 9: 1341-1346
3. Liu J, Harberts E, Tammaro A, IL-9 regulates allergen-specific Th1 responses in allergic contact dermatitis. J Invest Dermatol 2014; 134: 1903-1911