Development of an Experimental Model of Diabetes Co-Existing with Metabolic Syndrome in Rats

Advances in Pharmacological Sciences

Volumn 2016, Issue , 2016, Pages

  Suman, Rajesh Kumar ^a   Ray Mohanty, Ipseeta ^a   Borde, Manjusha K ^a   Maheshwari, Ujwala ^a   Deshmukh, Y A ^a  

^a MGM Medical College   (India)

Author keywords

[No Author keywords available]

Indexed keywords

C PEPTIDE; CHOLESTEROL; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROGENESIS; CARDITIS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DIABETES MELLITUS; DYSLIPIDEMIA; GLUCOSE BLOOD LEVEL; HEART EDEMA; HEART INJURY; HEART MUSCLE NECROSIS; HISTOPATHOLOGY; HYPERGLYCEMIA; HYPERTENSION; INSULIN BLOOD LEVEL; KIDNEY; KIDNEY FUNCTION; LIPID DIET; LIVER; MALE; METABOLIC SYNDROME X; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; RAT MODEL; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 84955597698     PISSN: 16876334     EISSN: 16876342     Source Type: Journal    
DOI: 10.1155/2016/9463476     Document Type: Article

References (25)

1. K. G. M. M. Alberti, R. H. Eckel, S. M. Grundy et al., "Harmonizing the metabolic syndrome: a joint interim statement of the international diabetes federation task force on epidemiology and prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the study of obesity, " Circulation, vol. 120, no. 16, pp. 1640-1645, 2009.
2. J. S. Torgerson, J. Hauptman, M. N. Boldrin, and L. Sjöström, "XENical in the Prevention of Diabetes in Obese Subjects (XENDOS) Study. A randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients, " Diabetes Care, vol. 27, no. 1, pp. 155-161, 2004.
3. A. Guilherme, J. V. Virbasius, V. Puri, and M. P. Czech, "Adi-pocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes, " Nature Reviews Molecular Cell Biology, vol. 9, no. 5, pp. 367-377, 2008.
4. K.-H. Yoon, J.-H. Lee, J.-W. Kim et al., "Epidemic obesity and type 2 diabetes in Asia, " The Lancet, vol. 368, no. 9548, pp. 1681-1688, 2006.
5. G. I. Bell and K. S. Polonsky, "Diabetes mellitus and genetically programmed defects in?-cell function, " Nature, vol. 414, no. 6865, pp. 788-791, 2001.
6. J. E. Shaw, R. A. Sicree, and P. Z. Zimmet, "Global estimates of the prevalence of diabetes for 2010 and 2030, " Diabetes Research and Clinical Practice, vol. 87, no. 1, pp. 4-14, 2010.
7. N. Unwin, D. Gan, and D. Whiting, "The IDF Diabetes Atlas: providing evidence, raising awareness and promoting action, " Diabetes Research and Clinical Practice, vol. 87, no. 1, pp. 2-3, 2010.
8. X.-K.Zheng, L.Zhang, W.-W. Wang, Y.-Y. Wu, Q.-B. Zhang, and W.-S. Feng, "Anti-diabetic activity and potential mechanism of total favonoids of Selaginella tamariscina (Beauv.) Spring in rats induced by high fat diet and low dose STZ, " Journal of Ethnopharmacology, vol. 137, no. 1, pp. 662-668, 2011.
9. S. Skovsø, "Modeling type 2 diabetes in rats using high fat diet and streptozotocin, " Journal of Diabetes Investigation, vol. 5, no. 4, pp. 349-358, 2014.
10. R. H. Unger, G. O. Clark, P. E. Scherer, and L. Orci, "Lipid home-ostasis, lipotoxicity and the metabolic syndrome, " Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids, vol. 1801, no. 3, pp. 209-214, 2010.
11. F. Franconi, G. Seghieri, S. Canu, E. Straface, I. Campesi, and W. Malorni, "Are the available experimental models of type 2 diabetes appropriate for a gender perspective?" Pharmacological Research, vol. 57, no. 1, pp. 6-18, 2008.
12. K. Sahin, M. Onderci, M. Tuzcu et al., "Efect of chromium on carbohydrate and lipid metabolism in a rat model of type 2 diabetes mellitus: the fat-fed, streptozotocin-treated rat, " Metabolism: Clinical and Experimental, vol. 56, no. 9, pp. 1233-1240, 2007.
13. K. Srinivasan, B. Viswanad, L. Asrat, C. L. Kaul, and P. Ramarao, "Combination of high-fat diet-fed and low-dose streptozotocin-treated rat: a model for type 2 diabetes and pharmacological screening, " Pharmacological Research, vol. 52, no. 4, pp. 313-320, 2005.
14. D. Kuate, A. Pascale, N. Kengne, C. P. N. Biapa, B. G. K. Azantsa, and W. A. B. W. Muda, "The t r a p l e u r a t e t r a p t e ra spice attenuates high-carbohydrate, high-fat diet-induced obese and type 2 diabetic rats with metabolic syndrome features, " Lipids in Health and Disease, vol. 14, article 50, 13 pages, 2015.
15. E. L. B. Novelli, Y. S. Diniz, C. M. Galhardi et al., "Anthropo-metrical parameters and markers of obesity in rats, " Laboratory Animals, vol. 41, no. 1, pp. 111-119, 2007.
16. L. S. Mansor, E. R. Gonzalez, M. A. Cole et al., "Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin, " Cardiovascular Diabetology, vol. 12, article 136, 10 pages, 2013.
17. Y. Wang, T. Campbell, B. Perry, C. Beaurepaire, and L. Qin, "Hypoglycemic and insulin-sensitizing efects of berberine in high-fat diet-and streptozotocin-induced diabetic rats, " Metabolism: Clinical and Experimental, vol. 60, no. 2, pp. 298-305, 2011.
18. P. Kehkashan and A. S. Waseem, "Protective efect of butea monospora on high fat diet and streptozotocin-induced non-genetic rat model of type 2 diabetes: biochemical & histopatho-logical evidence, " International Journal of Pharmacy and Pharmaceutical Sciences, vol. 3, no. 3, pp. 74-81, 2011.
19. N. M. El-Sheikh, "Mangifera indica leaves extract modulates serum leptin. Asymmetric dimethylarginine and endothelin-1 leaves in experimental diabetes mellitus, " Egyptian Journal of Biochemistry & Molecular Biology, vol. 30, no. 2, pp. 229-244, 2012.
20. A. A. Kamal, M. A. Ezzar, and A. N. Mohammad, "Efects of panax quindue of olium on streptozotocin induced diabetic rats: role of C-peptide. Nitric oxide & oxitadive stress, " International Journal of Clinical and Experimental Medicine, vol. 4, no. 2, pp. 136-147, 2011.
21. M. R. Shahraki, M. Harati, and A. R. Shahraki, "Prevention of high fructose-induced metabolic syndrome in male wistar rats by aqueous extract of Ta m a r i n d u s i n d i c a seed, " Acta Medica Iranica, vol. 49, no. 5, pp. 277-283, 2011.
22. R. P. Munshi, S. G. Joshi, and B. N. Rane, "Development of an experimental diet model in rats to study hyperlipidemia and insulin resistance, markers for coronary heart disease, " Indian Journal of Pharmacology, vol. 46, no. 3, pp. 270-276, 2014.
23. N. Mamikutty, Z. C. Tent, S. R. Sapri, N. N. Sahruddin, M. R. Mohd Yusof, and F. Haji Suhaimi, "The establishment of metabolic syndrome model by induction of fructose drinking water in male Wistar rats, " BioMed Research International, vol. 2014, Article ID 263897, 8 pages, 2014.
24. T. Zhang, S. Yang, and J. Du, "Protective efects of berberine on isoproterenol-induced acute myocardial ischemia in rats through regulating hmgb1-tlr4 axis, " Evidence-Based Complementary and Alternative Medicine, vol. 2014, Article ID 849783, 8 pages, 2014.
25. N. F. Renna, E. A. Diez, and R. M. Miatello, "Efects of dipep-tidyl-peptidase 4 inhibitor about vascular infammation in a metabolic syndrome model, " PLoS ONE, vol. 9, no. 9, Article ID e106563, 2014.