TNF receptor-2 facilitates an immunosuppressive microenvironment in the liver to promote the colonization and growth of hepatic metastases

Cancer Research

Volumn 75, Issue 24, 2015, Pages 5235-5245

  Ham, Boram ^a   Wang, Ni ^a   D'Costa, Zarina ^a   Fernandez, Maria Celia ^a   Bourdeau, France ^a   Auguste, Patrick ^b,c   Illemann, Martin ^d,e   Eefsen, Rikke Loevendahl ^d,e   Høyer Hansen, Gunilla ^d,e   Vainer, Ben ^d   Evrard, Maximilien ^f,g   Gao, Zu Hua ^a   Brodt, Pnina ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITÉ DE BORDEAUX   (France)

^c INSERM   (France)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

^e UNIVERSITY OF COPENHAGEN   (Denmark)

^f UNIVERSITÉ PARIS DESCARTES   (France)

^g AGENCY FOR SCIENCE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CD33 ANTIGEN; CD4 ANTIGEN; CHEMOKINE RECEPTOR CXCR2; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; HLA DR ANTIGEN; INTERCELLULAR ADHESION MOLECULE 1; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; CANCER INCIDENCE; CELL INFILTRATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LIVER METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; REGULATORY T LYMPHOCYTE; REVIEW; TUMOR MICROENVIRONMENT; UPREGULATION; ADOPTIVE TRANSFER; ANIMAL; BONE MARROW CELL; C57BL MOUSE; COLON TUMOR; CONFOCAL MICROSCOPY; DISEASE MODEL; FLOW CYTOMETRY; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; KNOCKOUT MOUSE; LIVER TUMOR; LUNG TUMOR; METASTASIS; POLYMERASE CHAIN REACTION; SECONDARY; TUMOR ASSOCIATED LEUKOCYTE; TUMOR ESCAPE;

ADOPTIVE TRANSFER; ANIMALS; COLONIC NEOPLASMS; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER NEOPLASMS; LUNG NEOPLASMS; LYMPHOCYTES, TUMOR-INFILTRATING; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MYELOID CELLS; NEOPLASM METASTASIS; POLYMERASE CHAIN REACTION; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; TUMOR ESCAPE; TUMOR MICROENVIRONMENT;

EID: 84955488156     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-3173     Document Type: Review

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