The role of secreted protein acidic and rich in cysteine (SPARC) in cardiac repair and fibrosis: Does expression of SPARC by macrophages influence outcomes?

Journal of Molecular and Cellular Cardiology

Volumn 93, Issue , 2016, Pages 156-161

  Bradshaw, Amy D ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b RALPH H JOHNSON VA MEDICAL CENTER   (United States)

Author keywords

BM40; Collagen; Extracellular matrix; Inflammation; Matricellular; Osteonectin

Indexed keywords

OSTEONECTIN; SPARC PROTEIN, HUMAN;

AGING; CARDITIS; CELL ADHESION; CELL FUNCTION; CELL INTERACTION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; EXTRACELLULAR MATRIX; HEART MUSCLE FIBROSIS; HEART VENTRICLE OVERLOAD; HUMAN; NONHUMAN; OUTCOME ASSESSMENT; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; REVIEW; TISSUE REPAIR; TUMOR ASSOCIATED LEUKOCYTE; AGE; ANIMAL; BLOOD PRESSURE; CARDIAC MUSCLE; FIBROSIS; GENE EXPRESSION; GENETICS; HEART INFARCTION; IMMUNOLOGY; MACROPHAGE; MACROPHAGE ACTIVATION; MECHANICS; MECHANOTRANSDUCTION; METABOLISM; MYOCARDITIS; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; PATHOPHYSIOLOGY; WOUND HEALING;

AGE FACTORS; ANIMALS; BLOOD PRESSURE; CHEMOTAXIS, LEUKOCYTE; FIBROSIS; GENE EXPRESSION; HUMANS; MACROPHAGE ACTIVATION; MACROPHAGES; MECHANICAL PHENOMENA; MECHANOTRANSDUCTION, CELLULAR; MYOCARDIAL INFARCTION; MYOCARDITIS; MYOCARDIUM; OSTEONECTIN; WOUND HEALING;

EID: 84955486870     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2015.11.014     Document Type: Review

References (32)

1. Trombetta-Esilva J., Bradshaw A.D. The function of SPARC as a mediator of fibrosis. Open Rheumatol. J. 2012, 6:146-155.
2. Ploetz C., Zycband E.I., Birk D.E. Collagen fibril assembly and deposition in the developing dermis: segmental deposition in extracellular compartments. J. Struct. Biol. 1991, 106:73-81.
3. Reed M.J., Puolakkainen P., Lane T.F., Dickerson D., Bornstein P., Sage E.H. Differential expression of SPARC and thrombospondin 1 in wound repair: immunolocalization and in situ hybridization. J. Histochem. Cytochem. 1993, 41:1467-1477.
4. Sangaletti S., Di Carlo E., Gariboldi S., Miotti S., Cappetti B., Parenza M., et al. Macrophage-derived SPARC bridges tumor cell-extracellular matrix interactions toward metastasis. Cancer Res. 2008, 68:9050-9059.
5. Bradshaw A.D., Baicu C.F., Rentz T.J., Van Laer A.O., Boggs J., Lacy J.M., et al. Pressure overload-induced alterations in fibrillar collagen content and myocardial diastolic function: role of secreted protein acidic and rich in cysteine (SPARC) in post-synthetic procollagen processing. Circulation 2009, 119:269-280.
6. Harris B.S., Zhang Y., Card L., Rivera L.B., Brekken R.A., Bradshaw A.D. SPARC regulates collagen interaction with cardiac fibroblast cell surfaces. Am. J. Physiol. Heart Circ. Physiol. 2011, 301:H841-H847.
7. Weisheit C., Zhang Y., Faron A., Kopke O., Weisheit G., Steinstrasser A., et al. Ly6C(low) and not Ly6C(high) macrophages accumulate first in the heart in a model of murine pressure-overload. PLoS ONE 2014, 9.
8. Martinez F.O., Gordon S. The M1 and M2 paradigm of macrophage activation: time for reassessment. F1000prime reports 2014, 6:13.
9. Nahrendorf M., Swirski F.K. Monocyte and macrophage heterogeneity in the heart. Circ. Res. 2013, 112:1624-1633.
10. Bradshaw A.D., Baicu C.F., Rentz T.J., Van Laer A.O., Bonnema D.D., Zile M.R. Age-dependent alterations in fibrillar collagen content and myocardial diastolic function: role of SPARC in post-synthetic procollagen processing. Am. J. Physiol. Heart Circ. Physiol. 2010, 298:H614-H622.
11. Toba H., de Castro Bras L.E., Baicu C.F., Zile M.R., Lindsey M.L., Bradshaw A.D. Secreted protein acidic and rich in cysteine facilitates age-related cardiac inflammation and macrophage M1 polarization. Am. J. Physiol. Cell Physiol. 2015, 308:C972-C982.
12. Frantz S., Nahrendorf M. Cardiac macrophages and their role in ischaemic heart disease. Cardiovasc. Res. 2014, 102:240-248.
13. Nahrendorf M., Swirski F.K., Aikawa E., Stangenberg L., Wurdinger T., Figueiredo J.L., et al. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J. Exp. Med. 2007, 204:3037-3047.
14. Schellings M.W., Vanhoutte D., Swinnen M., Cleutjens J.P., Debets J., van Leeuwen R.E., et al. Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction. J. Exp. Med. 2009, 206:113-123.
15. Bradshaw A.D., Puolakkainen P., Dasgupta J., Davidson J.M., Wight T.N., Sage E.H. SPARC-null mice display abnormalities in the dermis characterized by decreased collagen fibril diameter and reduced tensile strength. J. Investig. Dermatol. 2003, 120:949-955.
16. McCurdy S.M., Dai Q., Zhang J., Zamilpa R., Ramirez T.A., Dayah T., et al. SPARC mediates early extracellular matrix remodeling following myocardial infarction. Am. J. Physiol. Heart Circ. Physiol. 2011, 301:H497-H505.
17. Sangaletti S., Gioiosa L., Guiducci C., Rotta G., Rescigno M., Stoppacciaro A., et al. Accelerated dendritic-cell migration and T-cell priming in SPARC-deficient mice. J. Cell Sci. 2005, 118:3685-3694.
18. Ng Y.L., Klopcic B., Lloyd F., Forrest C., Greene W., Lawrance I.C. Secreted protein acidic and rich in cysteine (SPARC) exacerbates colonic inflammatory symptoms in dextran sodium sulphate-induced murine colitis. PLoS ONE 2013, 8.
19. Socha M.J., Manhiani M., Said N., Imig J.D., Motamed K. Secreted protein acidic and rich in cysteine deficiency ameliorates renal inflammation and fibrosis in angiotensin hypertension. Am. J. Pathol. 2007, 171:1104-1112.
20. Rempel S.A., Hawley R.C., Gutierrez J.A., Mouzon E., Bobbitt K.R., Lemke N., et al. Splenic and immune alterations of the SPARC-null mouse accompany a lack of immune response. Genes Immun. 2007, 8:262-274.
21. Sangaletti S., Tripodo C., Cappetti B., Casalini P., Chiodoni C., Piconese S., et al. SPARC oppositely regulates inflammation and fibrosis in bleomycin-induced lung damage. Am. J. Pathol. 2011, 179:3000-3010.
22. Arnold S.A., Rivera L.B., Miller A.F., Carbon J.G., Dineen S.P., Xie Y., et al. Lack of host SPARC enhances vascular function and tumor spread in an orthotopic murine model of pancreatic carcinoma. Dis. Model. Mech. 2010, 3:57-72.
23. Arnold S.A., Rivera L.B., Carbon J.G., Toombs J.E., Chang C.L., Bradshaw A.D., et al. Losartan slows pancreatic tumor progression and extends survival of SPARC-null mice by abrogating aberrant TGFbeta activation. PLoS ONE 2012, 7.
24. Sangaletti S., Stoppacciaro A., Guiducci C., Torrisi M.R., Colombo M.P. Leukocyte, rather than tumor-produced SPARC, determines stroma and collagen type IV deposition in mammary carcinoma. J. Exp. Med. 2003, 198:1475-1485.
25. Bradshaw A.D. The role of SPARC in extracellular matrix assembly. J. Cell. Commun. Signal. 2009, 3:239-246.
26. Kelly K.A., Allport J.R., Yu A.M., Sinh S., Sage E.H., Gerszten R.E., et al. SPARC is a VCAM-1 counter-ligand that mediates leukocyte transmigration. J. Leukoc. Biol. 2007, 81:748-756.
27. Kzhyshkowska J., Workman G., Cardo-Vila M., Arap W., Pasqualini R., Gratchev A., et al. Novel function of alternatively activated macrophages: stabilin-1-mediated clearance of SPARC. J. Immunol. 2006, 176:5825-5832.
28. Martinez F.O., Helming L., Milde R., Varin A., Melgert B.N., Draijer C., et al. Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences. Blood 2013, 121:e57-e69.
29. Belkin A.M. Extracellular TG2: emerging functions and regulation. FEBS J. 2011, 278:4704-4716.
30. Trombetta-eSilva J., Rosset E.A., Hepfer R.G., Wright G.J., Baicu C., Yao H., et al. Decreased mechanical strength and collagen content in SPARC-null periodontal ligament is reversed by inhibition of transglutaminase activity. J. Bone Miner. Res. Off. J. Am. Soc. Bone Miner. Res. 2015.
31. Dobaczewski M., Gonzalez-Quesada C., Frangogiannis N.G. The extracellular matrix as a modulator of the inflammatory and reparative response following myocardial infarction. J. Mol. Cell. Cardiol. 2010, 48:504-511.
32. Charest A., Pepin A., Shetty R., Cote C., Voisine P., Dagenais F., et al. Distribution of SPARC during neovascularisation of degenerative aortic stenosis. Heart 2006, 92:1844-1849.