Genetic loci on chromosome 5 are associated with circulating levels of interleukin-5 and eosinophil count in a European population with high risk for cardiovascular disease

Cytokine

Volumn 81, Issue , 2016, Pages 1-9

  McLeod, Olga ^a   Silveira, Angela ^a   Valdes Marquez, Elsa ^b   Björkbacka, Harry ^c   Almgren, Peter ^c   Gertow, Karl ^a   Gådin, Jesper R ^a   Bäcklund, Alexandra ^a   Sennblad, Bengt ^a   Baldassarre, Damiano ^d,e   Veglia, Fabrizio ^e   Humphries, Steve E ^f   Tremoli, Elena ^d,e   de Faire, Ulf ^a   Nilsson, Jan ^c   Melander, Olle ^c   Hopewell, Jemma C ^b   Clarke, Robert ^b   Björck, Hanna M ^a   Hamsten, Anders ^a   Öhrvik, John ^a,g   Strawbridge, Rona J ^a   more..

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c LUND UNIVERSITY   (Sweden)

^d UNIVERSITY OF MILAN   (Italy)

^e CENTRO CARDIOLOGICO MONZINO   (Italy)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

^g UPPSALA UNIVERSITY   (Sweden)

Author keywords

Eosinophil count; Genetics; IL 5; Intima media thickness; RAD50; Subclinical atherosclerosis

Indexed keywords

INTERLEUKIN 5; MESSENGER RNA; DNA BINDING PROTEIN; DNA LIGASE; RAD50 PROTEIN, HUMAN;

ADULT; AGED; ARTERIAL WALL THICKNESS; ARTICLE; CHROMOSOME 14; CHROMOSOME 5; CORONARY ARTERY DISEASE; EOSINOPHIL COUNT; EUROPEAN; FEMALE; GENE EXPRESSION; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; HIGH RISK PATIENT; HUMAN; IL5 GENE; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; ATHEROSCLEROTIC PLAQUE; BLOOD; EOSINOPHIL; EUROPE; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; LEUKOCYTE COUNT; METABOLISM; MIDDLE AGED; POPULATION GENETICS; PROCEDURES; RISK FACTOR; STATISTICAL MODEL;

AGED; CAROTID INTIMA-MEDIA THICKNESS; CHROMOSOMES, HUMAN, PAIR 14; CHROMOSOMES, HUMAN, PAIR 5; CORONARY ARTERY DISEASE; DNA REPAIR ENZYMES; DNA-BINDING PROTEINS; EOSINOPHILS; EUROPE; FEMALE; GENE EXPRESSION; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENETICS, POPULATION; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INTERLEUKIN-5; LEUKOCYTE COUNT; LINEAR MODELS; MALE; MIDDLE AGED; PLAQUE, ATHEROSCLEROTIC; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 84955476020     PISSN: 10434666     EISSN: 10960023     Source Type: Journal    
DOI: 10.1016/j.cyto.2016.01.007     Document Type: Article

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