Sonic hedgehog delivery from self-assembled nanofiber hydrogels reduces the fibrotic response in models of erectile dysfunction

Acta Biomaterialia

Volumn 32, Issue , 2016, Pages 89-99

  Choe, Shawn ^a   Veliceasa, Dorina ^a   Bond, Christopher W ^b   Harrington, Daniel A ^c   Stupp, Samuel I ^d,e   Mcvary, Kevin T ^f   Podlasek, Carol A ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c RICE UNIVERSITY   (United States)

^d NORTHWESTERN UNIVERSITY   (United States)

^e Northwestern University   (United States)

^f SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cavernous nerve injury; Collagen; Penis; Self assembling peptide amphiphile nanofiber hydrogels; Sonic hedgehog

Indexed keywords

AMPHIPHILES; COLLAGEN; HYDROGELS; PATIENT TREATMENT; PEPTIDES; RATS; UROLOGY;

CAVERNOI NERVE INJURY; CONDITION; DIABETICS PATIENTS; ERECTILE DYSFUNCTION; NERVE INJURIES; PENIS; PEPTIDE AMPHIPHILES; SELF-ASSEMBLING PEPTIDE AMPHIPHILE NANOFIBER HYDROGEL; SELF-ASSEMBLING PEPTIDES; SONIC HEDGEHOGS;

NANOFIBERS;

AMPHOPHILE; COLLAGEN; NANOFIBER; SONIC HEDGEHOG PROTEIN; HYDROGEL; HYDROXYPROLINE; PEPTIDE;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CAVERNOUS NERVE; CONTROLLED STUDY; CORPUS CAVERNOSUM; DIABETES MELLITUS; DRUG DELIVERY SYSTEM; ERECTILE DYSFUNCTION; HUMAN; HUMAN TISSUE; HYDROGEL; INJURY SEVERITY; INNERVATION; MORPHOLOGY; NERVE INJURY; NONHUMAN; PARASYMPATHETIC NERVE; PELVIC GANGLION; PENILE FIBROSIS; PENIS; PRIORITY JOURNAL; PROSTATECTOMY; RAT; REGENERATION; SMOOTH MUSCLE; ANIMAL; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; FIBROSIS; GANGLION; IMMUNOHISTOCHEMISTRY; MALE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; STAINING; TIME FACTOR;

ANIMALS; COLLAGEN; DIABETES MELLITUS; DISEASE MODELS, ANIMAL; DRUG DELIVERY SYSTEMS; ERECTILE DYSFUNCTION; FIBROSIS; GANGLIA; HEDGEHOG PROTEINS; HUMANS; HYDROGELS; HYDROXYPROLINE; IMMUNOHISTOCHEMISTRY; MALE; NANOFIBERS; PENIS; PEPTIDES; PROSTATECTOMY; RATS, SPRAGUE-DAWLEY; STAINING AND LABELING; TIME FACTORS;

EID: 84955275441     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2016.01.014     Document Type: Article

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