β-Sarcoglycan gene transfer decreases fibrosis and restores force in LGMD2E mice

Gene Therapy

Volumn 23, Issue 1, 2016, Pages 57-66

  Pozsgai, E R ^a,b   Griffin, D A ^b   Heller, K N ^a,b   Mendell, J R ^a,b   Rodino Klapac, L R ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SARCOGLYCAN; BETA SARCOGLYCAN; COLLAGEN; COMPLEMENTARY DNA; DYSTROPHIN; SARCOGLYCAN; TRANSCRIPTION FACTOR E2A; VIRUS VECTOR; SGCB PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ECCENTRIC MUSCLE CONTRACTION; FEMALE; GENE EXPRESSION; GENE TRANSFER; HISTOLOGY; LIMB GIRDLE MUSCULAR DYSTROPHY; LIMB GIRDLE MUSCULAR DYSTROPHY TYPE 2E; MACROPHAGE; MALE; MONONUCLEAR CELL; MOUSE; MUSCLE CELL; MUSCLE FUNCTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; SIMIAN VIRUS 40; SKELETAL MUSCLE; VIRAL GENE DELIVERY SYSTEM; ANIMAL; DEPENDOPARVOVIRUS; DISEASE MODEL; DRUG EFFECTS; FIBROSIS; GENE THERAPY; GENE VECTOR; GENETICS; HUMAN; KNOCKOUT MOUSE; METABOLISM; MUSCULAR DYSTROPHIES; MUTATION; PATHOPHYSIOLOGY; PROCEDURES; SARCOGLYCANOPATHIES;

ANIMALS; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; FEMALE; FIBROSIS; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; GENETIC VECTORS; HUMANS; MALE; MICE; MICE, KNOCKOUT; MUSCLE, SKELETAL; MUSCULAR DYSTROPHIES; MUTATION; SARCOGLYCANOPATHIES; SARCOGLYCANS;

EID: 84955215428     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2015.80     Document Type: Article

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