Trends in sepsis incidence and outcomes among people with or without type 2 diabetes mellitus in Spain (2008-2012)

Diabetes Research and Clinical Practice

Volumn 110, Issue 3, 2015, Pages 266-275

  de Miguel Yanes, J M ^a   Mendez Bailon M ^b   Jimenez Garcia R ^c   Hernandez Barrera V ^c   Perez Farinos N ^d   Lopez de Andres A ^c  

^a HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑÓN   (Spain)

^b HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^c UNIVERSIDAD REY JUAN CARLOS   (Spain)

^d Social Policy and Equality ^*  (Spain)

Author keywords

In hospital mortality; Incidence; Sepsis; Septic shock; Type 2 diabetes mellitus

Indexed keywords

ADULT; AGE; AGED; ARTICLE; COHORT ANALYSIS; COMORBIDITY; FEMALE; HOSPITAL DISCHARGE; HUMAN; INCIDENCE; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MORTALITY; MULTIVARIATE ANALYSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; OBSERVATIONAL STUDY; PROGNOSIS; RETROSPECTIVE STUDY; RISK ASSESSMENT; SEPSIS; SEPTIC SHOCK; SPAIN; UNIVARIATE ANALYSIS; VERY ELDERLY; YOUNG ADULT; COMPLICATION; DIABETES MELLITUS, TYPE 2; HOSPITAL MORTALITY; HOSPITALIZATION; TRENDS;

AGED; AGED, 80 AND OVER; DIABETES MELLITUS, TYPE 2; FEMALE; HOSPITAL MORTALITY; HOSPITALIZATION; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; RETROSPECTIVE STUDIES; SEPSIS; SPAIN;

EID: 84955213410     PISSN: 01688227     EISSN: 18728227     Source Type: Journal    
DOI: 10.1016/j.diabres.2015.10.008     Document Type: Article

References (31)

1. Dellinger R.P., Levy M.M., Rhodes A., Annane D., Gerlach H., Opal S.M., et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Med 2013, 39:165-228.
2. Dombrovskiy V.Y., Martin A.A., Sunderram J., Paz H.L. Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: a trend analysis from 1993 to 2003. Crit Care Med 2007, 35:1244-1250.
3. Banta J.E., Joshi K.P., Beeson L., Nguyen H.B. Patient and hospital characteristics associated with inpatient severe sepsis mortality in California, 2005-2010. Crit Care Med 2012, 40:2960-2966.
4. Martin G.S., Mannino D.M., Eaton S., Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003, 348:1546-1554.
5. Slynkova K., Mannino D.M., Martin G.S., Morehead R.S., Doherty D.E. The role of body mass index and diabetes in the development of acute organ failure and subsequent mortality in an observational cohort. Crit Care 2006, 10:R137.
6. Graham B.B., Keniston A., Gajic O., Trillo Alvarez C.A., Medvedev S., Douglas I.S. Diabetes mellitus does not adversely affect outcomes from a critical illness. Crit Care Med 2010, 38:16-24.
7. Siegelaar S.E., Hickmann M., Hoekstra J.B., Holleman F., DeVries J.H. The effect of diabetes on mortality in critically ill patients: a systematic review and meta-analysis. Crit Care 2011, 15:R205. 10.1186/cc10440.
8. Chang C.W., Kok V.C., Tseng T.C., Horng J.T., Liu C.E. Diabetic patients with severe sepsis admitted to intensive care unit do not fare worse than non-diabetic patients: a nationwide population-based cohort study. PLOS ONE 2012, 7:e50729. www.plosone.org.
9. Gaieski D.F., Edwards J.M., Kallan M.J., Carr B.G. Benchmarking the incidence and mortality of severe sepsis in the United States. Crit Care Med 2013, 41:1167-1174.
10. Wilhelms S.B., Huss F.R., Granath G., Sjöberg F. Assessment of incidence of severe sepsis in Sweden using different ways of abstracting International Classification of Diseases codes: difficulties with methods and interpretation of results. Crit Care Med 2010, 38:1442-1449.
11. Ayala-Ramírez O.H., Domínguez-Berjón M.F., Esteban-Vasallo M.D. Trends in hospitalizations of patients with sepsis and factors associated with inpatient mortality in the Region of Madrid, 2003-2011. Eur J Clin Microbiol Infect Dis 2014, 33:411-421.
12. Instituto Nacional de Gestión Sanitaria, Ministerio de Sanidad y Consumo: Conjunto Mínimo Básico de Datos, Hospitales del INSALUD 2013, Available at http://www.ingesa.msc.es/estadEstudios/documPublica/CMBD-2001.htm [accessed 03.12.13].
13. [accessed 03.12.13]. http://www.cdc.gov/nchs/icd/icd9cm.htm.
14. Lagu T., Rothberg M.B., Shieh M.S., Pekow P.S., Steingrub J.S., Lindenauer P.K. What is the best method for estimating the burden of severe sepsis in the United States?. J Crit Care 2012, 27:414.e1-414.e9.
15. Angus D.C., Linde-Zwirble W.T., Lidicker J., Clermont G., Carcillo J., Pinsky M.R. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001, 7:1303-1310.
16. Charlson M.E., Pompei P., Ales K.L., MacKenzie C.R. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987, 40:373-383.
17. Deyo R.A., Cherkin D.C., Ciol M.A. Adapting a clinical comorbidity index for use with ICD-9-CM administrative databases. J Clin Epidemiol 1992, 45:613-619.
18. Instituto Nacional de Estadística (INE) Population estimates 2013, Available at http://www.ine.es [accessed 03.12.13].
19. Esteban A., Frutos-Vivar F., Ferguson N.D., Peñuelas O., Lorente J.A., Gordo F., et al. Sepsis incidence and outcome: contrasting the intensive care unit with the hospital ward. Crit Care Med 2007, 35:1284-1289.
20. Iribarren-Diarasarri S., Latorre-García K., Muñoz-Martínez T., Poveda-Hernández Y., Dudagoitia-Otaolea J.L., Martínez-Alutiz S., et al. Limitation of therapeutic effort after ICU admission. Analysis of related factors. Med Intensiva 2007, 31:68-72.
21. Kumar G., Kumar N., Taneja A., Kaleekal T., Tarima S., McGinley E., et al. Nationwide trends of severe sepsis in the 21st century (2000-2007). Chest 2011, 140:1223-1231.
22. Kuperman E.F., Showalter J.W., Lehman E.B., Leib A.E., Kraschnewski J.L. The impact of obesity on sepsis mortality: a retrospective review. BMC Infect Dis 2013, 13:377.
23. Kaukonen K.M., Bailey M., Suzuki S., Pilcher D., Bellomo R. Mortality related to severe sepsis and septic shock among critically ill patients in Australia and New Zealand, 2000-2012. JAMA 2014, 311:1308-1316.
24. Malinis M.F., Mawhorter S.D., Jain A., Shrestha N.K., Avery R.K., van Duin D. Staphylococcus aureus bacteremia in solid organ transplant recipients: evidence for improved survival when compared with nontransplant patients. Transplantation 2012, 93:1045-1050.
25. Coughlan M.T., Permezel M., Georgiou H.M., Rice G.E. Repression of oxidant-induced nuclear factor-kappaB activity mediates placental cytokine responses in gestational diabetes. J Clin Endocrinol Metab 2004, 89:3585-3594.
26. Esper A.M., Moss M., Martin G.S. The effect of diabetes mellitus on organ dysfunction with sepsis: an epidemiological study. Crit Care 2012, 13:R18. 10.1186/cc7717.
27. Yang Y., Salam Z.H., Ong B.C., Yang K.S. Respiratory dysfunction in patients with sepsis: protective effect of diabetes mellitus. Am J Crit Care 2011, 20:e41-e47.
28. Peake S.L., Moran J.L., Ghelani D.R., Lloyd A.J., Walker M.J. The effect of obesity on 12-month survival following admission to intensive care: a prospective study. Crit Care Med 2006, 34:2929-2939.
29. Koh G.C.K.W., Peacock S.J., van der Poll T., Wiersinga W.J. The impact of diabetes on the pathogenesis of sepsis. Eur J Clin Microbiol Infect Dis 2012, 31:379-388.
30. Leong A., Dasgupta K., Bernatsky S., Lacaille D., Avina-Zubieta A., Rahme E. Systematic review and meta-analysis of validation studies on a diabetes case definition from health administrative records. PLOS ONE 2013, 8:e75256.
31. Ribera A., Marsal J.R., Ferreira-González I., Cascant P., Pons J.M., Mitjavila F., et al. Predicting in-hospital mortality with coronary bypass surgery using hospital discharge data: comparison with a prospective observational study. Rev Esp Cardiol 2008, 61:843-852.