Patient and hospital characteristics associated with inpatient severe sepsis mortality in California, 2005-2010

Critical Care Medicine

Volumn 40, Issue 11, 2012, Pages 2960-2966

  Banta, Jim E ^a   Joshi, Kamlesh P ^a   Beeson, Lawrence ^a   Nguyen, H Bryant ^b  

^a Center for Community Health Development   (United States)

^b LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

California; general hospitals; health facility environment; mortality; sepsis; severe sepsis

Indexed keywords

ADULT; AGED; AGING; ARTICLE; DEMOGRAPHY; DISEASE SEVERITY; EMERGENCY CARE; FEMALE; HEALTH STATUS; HOSPITAL CARE; HOSPITAL PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAID; MORTALITY; PRIORITY JOURNAL; RACE DIFFERENCE; SEPSIS; UNITED STATES;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CALIFORNIA; CROSS-SECTIONAL STUDIES; FEMALE; HOSPITAL MORTALITY; HOSPITALIZATION; HUMANS; LOGISTIC MODELS; MALE; MEDICAL AUDIT; MIDDLE AGED; PATIENT DISCHARGE; RETROSPECTIVE STUDIES; SEPSIS; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 84868208082     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31825bc92f     Document Type: Article

References (33)

1. Wang HE, Shapiro NI, Angus DC, et al: National estimates of severe sepsis in United States emergency departments. Crit Care Med 2007; 35:1928-1936
2. Mayr FB, Yende S, Linde-Zwirble WT, et al: Infection rate and acute organ dysfunction risk as explanations for racial differences in severe sepsis. JAMA 2010; 303:2495-2503
3. Lagu T, Rothberg MB, Shieh MS, et al: Hospitalizations, costs, and outcomes of severe sepsis in the United States 2003 to 2007. Crit Care Med 2012; 40:754-761
4. Angus DC, Linde-Zwirble WT, Lidicker J, et al: Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001; 29:1303-1310
5. Dombrovskiy VY, Martin AA, Sunderram J, et al: Rapid increase in hospitalization and mortality rates for severe sepsis in the United States: A trend analysis from 1993 to 2003. Crit Care Med 2007; 35:1244-1250
6. Martin GS, Mannino DM, Eaton S, et al: The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003; 348:1546-1554
7. Barnato AE, Alexander SL, Linde-Zwirble WT, et al: Racial variation in the incidence, care, and outcomes of severe sepsis: Analysis of population, patient, and hospital characteristics. Am J Respir Crit Care Med 2008; 177:279-284
8. Esper AM, Moss M, Lewis CA, et al: The role of infection and comorbidity: Factors that influence disparities in sepsis. Crit Care Med 2006; 34:2576-2582
9. Odetola FO, Gebremariam A, Freed GL: Patient and hospital correlates of clinical outcomes and resource utilization in severe pediatric sepsis. Pediatrics 2007; 119:487-494
10. Powell ES, Khare RK, Courtney DM, et al: Volume of emergency department admissions for sepsis is related to inpatient mortality: Results of a nationwide cross-sectional analysis. Crit Care Med 2010; 38: 2161-2168
11. Patient Discharge Data-public dataset. State of California, Office of Statewide Health Planning and Development 2010. Available at: http://www.oshpd.ca.gov/HID/Products/PatDischargeData/PublicDataSet/index.html. Accessed November 28, 2011
12. Annual financial data. State of California, Office of Statewide Health Planning and Development 2010. Available at: http://www.oshpd.ca.gov/hid/ Products/Hospitals/AnnFinanData/PivotProfles/default.asp. Accessed December 8, 2011
13. Gijsen R, Hoeymans N, Schellevis FG, et al: Causes and consequences of comorbidity: A review. J Clin Epidemiol 2001; 54:661-674
14. Charlson ME, Pompei P, Ales KL, et al: A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. J Chronic Dis 1987; 40:373-383
15. Quan H, Sundararajan V, Halfon P, et al: Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med Care 2005; 43:1130-1139
16. Romley JA, Jena AB, Goldman DP: Hospital spending and inpatient mortality: Evidence from California: An observational study. Ann Intern Med 2011; 154:160-167
17. Allison PD: Missing Data. Thousand Oaks, CA: Sage, 2002
18. Yuan Y: Multiple Imputation for Missing Data: Concepts and New Development. Rockville, MD: SAS Institute Inc., 2005. Available at: http://support.sas.com/rnd/app/papers/multipleimputation.pdf. Accessed February 20, 2012
19. Cho T, Nguyen HB, Hayes SR, et al: Evaluation of APACHE II, SAPS II, MPM II, and MEDS for the prognostication of severe sepsis or septic shock in the emergency department. Crit Care Med 2006; 34:A2
20. Crowe CA, Kulstad EB, Mistry CD, et al: Comparison of severity of illness scoring systems in the prediction of hospital mortality in severe sepsis and septic shock. J Emerg Trauma Shock 2010; 3:342-347
21. Bateman BT, Schmidt U, Berman MF, et al: Temporal trends in the epidemiology of severe postoperative sepsis after elective surgery: A large, nationwide sample. Anesthesiology 2010; 112:917-925
22. Jha AK, Shlipak MG, Hosmer W, et al: Racial differences in mortality among men hospitalized in the Veterans Affairs health care system. JAMA 2001; 285:297-303
23. Sarrazin MV, Cannon KT, Rosenthal GE, et al: Racial differences in mortality among veterans hospitalized for exacerbation of chronic obstructive pulmonary disease. J Natl Med Assoc 2009; 101:656-662
24. Melamed A, Sorvillo FJ: The burden of sepsisassociated mortality in the United States from 1999 to 2005: An analysis of multiple-causeof-death data. Crit Care 2009; 13:R28
25. Birkmeyer JD, Siewers AE, Finlayson EV, et al: Hospital volume and surgical mortality in the United States. N Engl J Med 2002; 346:1128-1137
26. Elixhauser A, Steiner C, Fraser I: Volume thresholds and hospital characteristics in the United States. Health Aff (Millwood) 2003; 22:167-177
27. Kahn JM, Goss CH, Heagerty PJ, et al: Hospital volume and the outcomes of mechanical ventilation. N Engl J Med 2006; 355:41-50
28. Levy MM, Rapoport J, Lemeshow S, et al: Association between critical care physician management and patient mortality in the intensive care unit. Ann Intern Med 2008; 148:801-809
29. Popovich MJ, Esfandiari S, Boutros A: A new ICU paradigm: Intensivists as primary critical care physicians. Cleve Clin J Med 2011; 78:697-700
30. Czura CJ: Merinoff symposium 2010: Sepsis-An international call to action. Mol Med 2010; 16:157-158
31. Offner PJ, Heit J, Roberts R: Implementation of a rapid response team decreases cardiac arrest outside of the intensive care unit. J Trauma 2007; 62:1223-1227; discussion 1227
32. Nguyen HB, Van Ginkel C, Batech M, et al: Comparison of Predisposition, Insult/Infection, Response, and Organ dysfunction, Acute Physiology And Chronic Health Evaluation II, and Mortality in Emergency Department Sepsis in patients meeting criteria for early goal-directed therapy and the severe sepsis resuscitation bundle. J Crit Care 2011 Oct 25. [Epub ahead of print]
33. Zajacova A, Dowd JB, Aiello AE: Socioeconomic and race/ethnic patterns in persistent infection burden among U.S. adults. J Gerontol A Biol Sci Med Sci 2009; 64:272-279