Iron regulation of hepcidin through Hfe and Hjv: Common or distinct pathways?

Hepatology

Volumn 62, Issue 6, 2015, Pages 1922-1923

  Pantopoulos, Kostas ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

HEPCIDIN; HLA ANTIGEN CLASS 1; IRON; MEMBRANE PROTEIN;

ANIMAL; FEMALE; GENETICS; HEMOCHROMATOSIS; HUMAN; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; FEMALE; HEMOCHROMATOSIS; HEPCIDINS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IRON; MEMBRANE PROTEINS; SIGNAL TRANSDUCTION;

EID: 84955203284     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.27777     Document Type: Article

References (4)

1. Wu Q, Wang H, An P, Tao Y, Deng J, Zhang Z, et al. HJV and HFE play distinct roles in regulating hepcidin. Antioxid Redox Signal. In press. doi: 10.1089/ars.2013.5819.
2. Kent P, Wilkinson N, Constante M, Fillebeen C, Gkouvatsos K, Wagner J, et al. Hfe and Hjv exhibit overlapping functions for iron signaling to hepcidin. J Mol Med (Berl). In press. doi: 10.1007/s00109-015-1253-7.
3. Wu XG, Wang Y, Wu Q, Cheng WH, Liu W, Zhao Y, et al. HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression. Blood 2014;124:1335-1343.
4. Ramos E, Kautz L, Rodriguez R, Hansen M, Gabayan V, Ginzburg Y, et al. Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice. Hepatology 2011;53:1333-1341.