Role of serum hepatitis B virus marker quantitation to differentiate natural history phases of HBV infection

Hepatology International

Volumn 10, Issue 1, 2016, Pages 133-138

  Wang, Li ^a   Zou, Zhi Qiang ^a   Wang, Kai ^b   Yu, Ji Guang ^a   Liu, Xiang Zhong ^a  

^a Infectious Disease Hospital of Yantai   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Differentiation; Hepatitis B virus marker; Infection; Natural history; Quantitation

Indexed keywords

HEPATITIS B CORE ANTIBODY; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; VIRUS DNA; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; DIFFERENTIATION ANTIGEN;

ADULT; ARTICLE; CHRONIC HEPATITIS B; CONTROLLED STUDY; DISEASE COURSE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PREDICTIVE VALUE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; BLOOD; GENETICS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; ISOLATION AND PURIFICATION; MIDDLE AGED; VIRUS LOAD;

ADULT; ALANINE TRANSAMINASE; ANTIGENS, DIFFERENTIATION; ASPARTATE AMINOTRANSFERASES; BIOMARKERS; DNA, VIRAL; FEMALE; HEPATITIS B E ANTIGENS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; IMMUNE TOLERANCE; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; VIRAL LOAD;

EID: 84955193798     PISSN: 19360533     EISSN: 19360541     Source Type: Journal    
DOI: 10.1007/s12072-015-9657-6     Document Type: Article

References (27)

1. Kao JH. Risk stratification of HBV infection in Asia-Pacific region. Clin Mol Hepatol 2014;20(3):223–237
2. Liaw YF, Chu CM. Hepatitis B virus infection. Lancet 2009;373:582–592
3. Azmi AN, Tan SS, Mohamed R. Practical approach in hepatitis B e antigen-negative individuals to identify treatment candidates. World J Gastroenterol 2014;20(34):12045–12055
4. Chan HL, Wong GL, Wong VW. A review of the natural history of chronic hepatitis B in the era of transient elastography. Antivir Ther 2009;14:489–499
5. Liaw YF, Kao JH, Piratvisuth T, et al. Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2012 update. Hepatol Int 2012;6:531–561
6. European Association for the Study of the Liver. EASL clinical practice guidelines: management of chronic hepatitis B virus infection. J Hepatol 2012;57(1):167–185
7. Sanai FM, Babatin MA, Bzeizi KI, et al. Accuracy of international guidelines for identifying significant fibrosis in hepatitis B e antigen-negative patients with chronic hepatitis. Clin Gastroenterol Hepatol 2013;11:1493–1499.e2
8. Villa E, Fattovich G, Mauro A, Pasino M. Natural history of chronic HBV infection: special emphasis on the prognostic implications of the inactive carrier state versus chronic hepatitis. Dig Liver Dis 2011;43(Suppl. 1):S8–S14
9. Liao B, Wang Z, Lin S, et al. Significant fibrosis is not rare in Chinese chronic hepatitis B patients with persistent normal ALT. PLoS One 2013;8(10):e78672
10. Gui HL, Wang H, Yang YH, et al. Significant histopathology in Chinese chronic hepatitis B patients with persistently high-normal alanine aminotransferase. J Viral Hepat 2010;17(Suppl. 1):44–50
11. Chotiyaputta W, Degertekin B, McKenna BJ, et al. Characteristics of chronic hepatitis B patients who underwent liver biopsies. J Viral Hepat 2011;18(11):792–803
12. Martinot-Peignoux M, Lapalus M, Asselah T, Marcellin P. HBsAg quantification: useful for monitoring natural history and treatment outcome. Liver Int 2014;34(Suppl. 1):97–107
13. Tseng TC, Liu CJ, Yang HC, et al. Serum hepatitis B surface antigen levels help predict disease progression in patients with low hepatitis B virus loads. Hepatology 2013;57(2):441–450
14. Chan HL, Wong VW, Wong GL, et al. A longitudinal study on the natural history of serum hepatitis B surface antigen changes in chronic hepatitis B. Hepatology 2010;52(4):1232–1241
15. Jia W, Song LW, Fang YQ, et al. Antibody to hepatitis B core antigen levels in the natural history of chronic hepatitis B: a prospective observational study. Medicine (Baltim) 2014;93(29):e322
16. Song LW, Liu PG, Liu CJ, et al. Quantitative hepatitis B core antibody levels in the natural history of hepatitis B virus infection. Clin Microbiol Infect 2015;21(2):197–203
17. Chinese Society of Hepatology, Chinese Medical Association, Chinese Society of Infectious Diseases. Guideline on prevention and treatment of chronic hepatitis B in China (2005). Chin Med J (Engl) 2007;120:2159–2173
18. Bedossa P, Poynard T, The French METAVIR Cooperative Study Group. An algorithm for grading activity in chronic hepatitis C. Hepatology 1996;24:289–293
19. Jaroszewicz J, Calle Serrano B, Wursthorn K, et al. Hepatitis B surface antigen (HBsAg) levels in the natural history of hepatitis B virus (HBV)-infection: a European perspective. J Hepatol 2010;52:514–522
20. Nguyen T, Thompson AJ, Bowden S, et al. Hepatitis B surface antigen levels during the natural history of chronic hepatitis B: a perspective on Asia. J Hepatol 2010;52:508–513
21. Hadziyannis SJ, Vassilopoulos D. Hepatitis B e antigen-negative chronic hepatitis B. Hepatology 2001;34:617–624
22. Kamitsukasa H, Iri M, Tanaka A, et al. Spontaneous reactivation of hepatitis B virus (HBV) infection in patients with resolved or occult HBV infection. J Med Virol 2015;87(4):589–600
23. Thimme R, Wieland S, Steiger C, et al. CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection. J Virol 2003;77(1):68–76
24. Tseng TC, Liu CJ, Yang WT, et al. Hepatitis B surface antigen level complements viral load in predicting viral reactivation in spontaneous HBeAg seroconverters. J Gastroenterol Hepatol 2014;29(6):1242–1249
25. Lee JM, Ahn SH. Quantification of HBsAg: basic virology for clinical practice. World J Gastroenterol 2011;17:283–289
26. Loggi E, Gamal N, Bihl F, Bernardi M, Andreone P. Adaptive response in hepatitis B virus infection. J Viral Hepat 2014;21(5):305–313
27. Lesmana CR, Jackson K, Lim SG, et al. Clinical significance of hepatitis B virion and SVP productivity: relationships between intrahepatic and serum markers in chronic hepatitis B patients. United Eur Gastroenterol J 2014;2(2):99–107