Treatment of growth plate injury using IGF-I-loaded PLGA scaffolds

Journal of Tissue Engineering and Regenerative Medicine

Volumn 9, Issue 12, 2015, Pages E202-E209

  Sundararaj, Sharath Kumar C ^a   Cieply, Ryan D ^b   Gupta, Gautam ^a,d   Milbrandt, Todd A ^b,c   Puleo, David A ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b UNIVERSITY OF KENTUCKY   (United States)

^c Shriners Hospital for Children   (United States)

^d Biomet Incorporated   (United States)

Author keywords

Drug delivery; Growth plate; IGF I; PLGA; Scaffold; Tissue engineering

Indexed keywords

BONE; CELL ENGINEERING; DEFECTS; PLATES (STRUCTURAL COMPONENTS); SCAFFOLDS (BIOLOGY); TARGETED DRUG DELIVERY; TISSUE REGENERATION;

CELL-FREE; GROWTH PLATE; IN-VIVO; INSULIN-LIKE GROWTH FACTOR-I; LOCALIZED DELIVERY; POLY LACTIC-CO-GLYCOLIC ACID; POLY(LACTIC-CO-GLYCOLIC ACID); TISSUES ENGINEERINGS; VIVO TISSUE ENGINEERING;

CONTROLLED DRUG DELIVERY;

POLYGLACTIN; SOMATOMEDIN C; DRUG CARRIER; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE INJURY; BONE MARROW STROMA CELL; CONTROLLED STUDY; CYTOKINE RELEASE; DEGRADATION KINETICS; DRUG RELEASE; GROWTH PLATE; GROWTH PLATE INJURY; HISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PILOT STUDY; PRIORITY JOURNAL; RAT; TISSUE ENGINEERING; TISSUE REGENERATION; TISSUE SECTION; ANIMAL; BONE MARROW CELL; EPIPHYSIS PLATE; EPIPHYSIS PLATE FRACTURE; INJURIES; METABOLISM; PATHOLOGY; RABBIT; SPRAGUE DAWLEY RAT; STROMA CELL; TIBIA;

ANIMALS; BONE MARROW CELLS; DRUG CARRIERS; GROWTH PLATE; INSULIN-LIKE GROWTH FACTOR I; LACTIC ACID; MALE; POLYGLYCOLIC ACID; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; SALTER-HARRIS FRACTURES; STROMAL CELLS; TIBIA;

EID: 84955192193     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.1670     Document Type: Article

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