An omics investigation into chronic widespread musculoskeletal pain reveals epiandrosterone sulfate as a potential biomarker

Pain

Volumn 156, Issue 10, 2015, Pages 1845-1851

  Livshits, Gregory ^a,b   Macgregor, Alexander J ^a,c   Gieger, Christian ^d   Malkin, Ida ^b   Moayyeri, Alireza ^a,e   Grallert, Harald ^d,f   Emeny, Rebecca T ^d   Spector, Tim ^a   Kastenmuller, Gabi ^a,d   Williams, Frances M K ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b TEL AVIV UNIVERSITY   (Israel)

^c UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^d INSTITUTE OF EPIDEMIOLOGY   (Germany)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

Author keywords

Biomarker; Chronic pain; Gene; Genome wide association; Metabolome

Indexed keywords

EPIANDROSTERONE; STEROID HORMONE; SULFATE; ANDROSTERONE; ANDROSTERONE SULFATE;

ADULT; AGE; ARTICLE; BODY COMPOSITION; BODY MASS; CHROMOSOME 17; CHRONIC PAIN; CHRONIC WIDESPREAD MUSCULOSKELETAL PAIN; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FAT MASS; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; METABOLITE; METABOLOMICS; MUSCULOSKELETAL PAIN; OBESITY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; ANALOGS AND DERIVATIVES; DIZYGOTIC TWINS; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; GERMANY; MALE; MENDELIAN RANDOMIZATION ANALYSIS; METABOLISM; MONOZYGOTIC TWINS; PHENOTYPE; TWINS; UNITED KINGDOM; YOUNG ADULT;

ADULT; ANDROSTERONE; BODY MASS INDEX; FEMALE; GENOME-WIDE ASSOCIATION STUDY; GENOMICS; GERMANY; HUMANS; MALE; MENDELIAN RANDOMIZATION ANALYSIS; MUSCULOSKELETAL PAIN; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; TWINS, DIZYGOTIC; TWINS, MONOZYGOTIC; UNITED KINGDOM; YOUNG ADULT;

EID: 84954566321     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1097/j.pain.0000000000000200     Document Type: Article

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