Is metabolic syndrome associated with obstructive sleep apnea in obese adolescents?

Journal of Clinical Sleep Medicine

Volumn 11, Issue 12, 2015, Pages 1371-1376

  Erdim, Ibrahim ^a   Akcay, Teoman ^b   Yilmazer, Rasim ^c,d   Erdur, Omer ^e   Kayhan, Fatma Tulin ^f  

^a Erbaa State Hospital   (Turkey)

^b Kanuni Sultan Suleyman Education and Research Hospital   (Turkey)

^c ISTANBUL MEDIPOL UNIVERSITY   (Turkey)

^d UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^e Konya Education and Research Hospital   (Turkey)

^f BAKIRKOY DR SADI KONUK TRAINING AND RESEARCH HOSPITAL   (Turkey)

Author keywords

Metabolic syndrome; Obesity; Pediatric sleep apnea syndrome

Indexed keywords

ADENOID HYPERTROPHY; ADENOTONSILLAR HYPERTROPHY; ADOLESCENT; ANTHROPOMETRIC PARAMETERS; APNEA HYPOPNEA INDEX; AROUSAL; ARTICLE; CHILD; DRUG USE; HUMAN; MAJOR CLINICAL STUDY; METABOLIC SYNDROME X; OBESITY; OXYGEN DESATURATION; POLYSOMNOGRAPHY; PREPUBERTY; PUBERTY; SCHOOL CHILD; SLEEP DISORDERED BREATHING; SNORING; BODY MASS; CHILDHOOD OBESITY; COMPLICATION; FEMALE; MALE;

ADOLESCENT; BODY MASS INDEX; FEMALE; HUMANS; MALE; METABOLIC SYNDROME X; PEDIATRIC OBESITY; POLYSOMNOGRAPHY; SLEEP APNEA, OBSTRUCTIVE;

EID: 84954522576     PISSN: 15509389     EISSN: 15509397     Source Type: Journal    
DOI: 10.5664/jcsm.5266     Document Type: Article

References (34)

1. World Health Organization. Nutrition. Controlling the global obesity epidemic. Available at: www.who.int/nut/obs.htm (accessed November 2004).
2. Ebbeling CB, Pawlak DB, Ludwig DS. Childhood obesity: public health crisis, common sense cure. Lancet 2002;360:473-82.
3. Ali NJ, Pitson DJ, Stradling JR. Snoring, sleep disturbance, and behavior in 4-5 year olds. Arch Dis Child 1993;68:360-6.
4. Gislason T, Benediktsdottir B. Snoring, apneic episodes and nocturnal hypoxemia among children 6 months to 6 years old. An epidemiologic study of lower limit of prevalence. Chest 1995;107:963-6.
5. Redline S, Tishler PV, Schluchter M, Aylor J, Clark K, Graham G. Risk factors for sleep-disordered breathing in children. Associations with obesity, race and respiratory problems. Am J Respir Crit Care Med 1999;159:1527-32.
6. Rosen CL, Larkin EK, Kirchner HL, et al. Prevalence and risk factors for sleep disordered breathing in 8- to 11-year-old children: association with race and prematurity. J Pediatr 2003;142:383-9.
7. Brouilette R, Hanson D, David R, et al. A diagnostic approach to suspected obstructive sleep apnea in children. J Pediatr 1984;105:10-4.
8. Marcus CL, Curtis S, Koerner CB, Joffe A, Serwint JR, Loughlin GM. Evaluation of respiratory complications in obese children/adolescents. Pediatr Pulmonol 1996;21:176-83.
9. Wing YK, Hui SH, Pak WM, et al. A controlled study of sleep related disordered breathing in obese children. Arch Dis Child 2003;88:1043-7.
10. de Ferranti SD, Gauvreau K, Ludwig DS, Neufeld EJ, Newburger JW, Rifai N. Prevalence of the metabolic syndrome in American adolescents: findings from the Third National Health and Nutrition Examination Survey. Circulation 2004;110:2494-7.
11. Grundy SM, Cleeman JI, Daniels SR, et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005;112:2735-52.
12. Huang PL. A comprehensive definition for metabolic syndrome. Dis Model Mech 2009;2:231-7.
13. Tagaya M, Nakata S, Yasuma F, et al. Relationship between adenoid size and severity of obstructive sleep apnea in preschool children. Int J Pediatr Otorhinolaryngol 2012;76:1827-30.
14. Hatipoglu N, Ozturk A, Mazicioglu MM, Kurtoglu S, Seyhan S, Lokoglu F. Waist circumference percentiles for 7- to 17-year-old Turkish children and adolescents. Eur J Pediatr 2008;167:383-9.
15. Alberti KG, Zimmet PZ, Shaw JE. The metabolic syndrome: a new worldwide definition from the International Diabetes Federation Consensus. Lancet 2005;366:1059-62.
16. American Thoracic Society. Standards and indications for cardiopulmonary sleep studies in children. Am J Respir Crit Care Med 1996;153:866-78.
17. Li AM, Chan MH, Chan DF, et al. Insulin and obstructive sleep apnea in obese Chinese children. Pediatr Pulmonol 2006;41:1175-81.
18. Carno MA, Ellis E, Anson E, et al. Symptoms of sleep apnea and polysomnography as predictors of poor quality of life in overweight children and adolescents. J Pediatr Psychol 2008;33:269-78.
19. Kahn A, Mozin MJ, Rebuffat E, et al. Sleep pattern alterations and brief airway obstructions in overweight infants. Sleep 1989;12:430-8.
20. Mallory GB Jr, Fiser DH, Jackson R. Sleep-associated breathing disorders in morbidly obese children and adolescents. J Pediatr 1989;115:892-7.
21. Marcus CL, Curtis S, Koerner CB, Joffe A, Serwint JR, Loughlin GM. Evaluation of pulmonary function and polysomnography in obese children and adolescents. Pediatr Pulmonol 1996;21:176-83.
22. Rosen CL. Clinical features of obstructive sleep apnea hypoventilation syndrome in otherwise healthy children. Pediatr Pulmonol 1999;27:403-9.
23. Silvestri JM, Weese-Mayer DE, Bass MT, Kenny AS, Hauptman SA, Pearsall SM. Polysomnography in obese children with a history of sleep-associated breathing disorders. Pediatr Pulmonol 1993;16:124-9.
24. Kalra M, Inge T, Garcia V, et al. Obstructive sleep apnea in extremely overweight adolescents undergoing bariatric surgery. Obes Res 2005;13:1175-9.
25. Redline S, Strohl KP. Recognition and consequences of obstructive sleep apnea hypopnea syndrome. Otolaryngol Clin North Am 1999;32:303-31.
26. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 1993;328:1230-5.
27. Ip MS, Lam B, Ng MM, Lam WK, Tsang KW, Lam KS. Obstructive sleep apnea is independently associated with insulin resistance. Am J Respir Crit Care Med 2002;165:670-6.
28. Redline S, Storfer-Isser A, Rosen CL, et al. Association between metabolic syndrome and sleep-disordered breathing in adolescents. Am J Respir Crit Care Med 2007;176:401-8.
29. Gozal D, Capdevila OS, Kheirandish-Gozal L. Metabolic alterations and systemic inflammation in obstructive sleep apnea among nonobese and obese prepubertal children. Am J Respir Crit Care Med 2008;177:1142-9.
30. Larkin EK, Rosen CL, Kirchner HL, et al. Variation of C-reactive protein levels in adolescents: association with sleep-disordered breathing and sleep duration. Circulation 2005;111:1978-84.
31. Tauman R, Ivanenko A, O'Brien LM, Gozal D. Plasma C-reactive protein levels among children with sleep-disordered breathing. Pediatrics 2004;113:564-9.
32. Kaditis AG, Alexopoulos EI, Kalampouka E, et al. Morning levels of C-reactive protein in children with obstructive sleep-disordered breathing. Am J Respir Crit Care Med 2005;171:282-6.
33. Dawson A, Abel SL, Loving RT, et al. CPAP therapy of obstructive sleep apnea in type 2 diabetics improves glycemic control during sleep. J Clin Sleep Med 2008;4:538-42.
34. Stefanini DOS, Barros EL, Stefanini R, et al. Comparing the clinical profile of non obese children with sleep apnea and snoring. Braz J Otorhinolaryngol 2012;78:22-6.