Treatment intensity, age and outcome in medical ICU patients: results of a French administrative database

Annals of Intensive Care

Volumn 6, Issue 1, 2016, Pages 1-8

  Peigne, Vincent ^a,b   Somme, Dominique ^c,d   Guérot, Emmanuel ^a,b   Lenain, Emilie ^a,b   Chatellier, Gilles ^a,b   Fagon, Jean Yves ^a,b   Saint Jean, Olivier ^a,b  

^a HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

^d UNIVERSITÉ DE RENNES 1   (France)

Author keywords

Intensive care; Mechanical ventilation; Older patients; Renal failure; Shock; Treatment intensity

Indexed keywords

ADULT; AGE; AGED; ARTICLE; FEMALE; HUMAN; INTENSIVE CARE; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; SIMPLIFIED ACUTE PHYSIOLOGY SCORE; STANDARDIZED MORTALITY RATIO; TREATMENT OUTCOME; VERY ELDERLY;

EID: 84954431510     PISSN: None     EISSN: 21105820     Source Type: Journal    
DOI: 10.1186/s13613-016-0107-y     Document Type: Article

References (28)

1. Bagshaw SM, Webb SAR, Delaney A, George C, Pilcher D, Hart GK, Bellomo R. Very old patients admitted to intensive care in Australia and New Zealand: a multi-centre cohort analysis. Crit Care. 2009;13:R45.
2. Le Gall JR, Lemeshow S, Saulnier F. A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA. 1993;270:2957–63.
3. Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med. 1985;13:818–29.
4. Knaus WA, Wagner DP, Draper EA, Zimmerman JE, Bergner M, Bastos PG, Sirio CA, Murphy DJ, Lotring T, Damiano A. The APACHE III prognostic system. Risk prediction of hospital mortality for critically ill hospitalized adults. Chest. 1991;100:1619–36.
5. Moreno RP, Metnitz PGH, Almeida E, Jordan B, Bauer P, Campos RA, Iapichino G, Edbrooke D, Capuzzo M, Le Gall J-R. SAPS 3–From evaluation of the patient to evaluation of the intensive care unit. Part 2: Development of a prognostic model for hospital mortality at ICU admission. Intensive Care Med. 2005;31:1345–55.
6. Hamel MB, Phillips RS, Davis RB, Desbiens N, Connors AF Jr, Teno JM, Wenger N, Lynn J, Wu AW, Fulkerson W, Tsevat J. Outcomes and cost-effectiveness of initiating dialysis and continuing aggressive care in seriously ill hospitalized adults. SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments. Ann Intern Med. 1997;127:195–202.
7. Hamel MB, Phillips RS, Davis RB, Teno J, Desbiens N, Lynn J, Tsevat J. Are aggressive treatment strategies less cost-effective for older patients? The case of ventilator support and aggressive care for patients with acute respiratory failure. J Am Geriatr Soc. 2001;49:382–90.
8. Ely EW, Wheeler AP, Thompson BT, Ancukiewicz M, Steinberg KP, Bernard GR. Recovery rate and prognosis in older persons who develop acute lung injury and the acute respiratory distress syndrome. Ann Intern Med. 2002;136:25–36.
9. De Rooij SE, Abu-Hanna A, Levi M, de Jonge E. Factors that predict outcome of intensive care treatment in very elderly patients: a review. Crit Care. 2005;9:R307–14.
10. Boumendil A, Somme D, Garrouste-Orgeas M, Guidet B. Should elderly patients be admitted to the intensive care unit? Intensive Care Med. 2007;33:1252–62.
11. Garrouste-Orgeas M, Montuclard L, Timsit J-F, Reignier J, Desmettre T, Karoubi P, Moreau D, Montesino L, Duguet A, Boussat S, Ede C, Monseau Y, Paule T, Misset B, Carlet J. Predictors of intensive care unit refusal in French intensive care units: a multiple-center study. Crit Care Med. 2005;33:750–5.
12. Garrouste-Orgeas M, Boumendil A, Pateron D, Aergerter P, Somme D, Simon T, Guidet B. Selection of intensive care unit admission criteria for patients aged 80 years and over and compliance of emergency and intensive care unit physicians with the selected criteria: an observational, multicenter, prospective study. Crit Care Med. 2009;37:2919–28.
13. Sprung CL, Artigas A, Kesecioglu J, Pezzi A, Wiis J, Pirracchio R, Baras M, Edbrooke DL, Pesenti A, Bakker J, Hargreaves C, Gurman G, Cohen SL, Lippert A, Payen D, Corbella D, Iapichino G. The Eldicus prospective, observational study of triage decision making in European intensive care units. Part II: intensive care benefit for the elderly. Crit Care Med. 2012;40:132–8.
14. Boumendil A, Aegerter P, Guidet B. Treatment intensity and outcome of patients aged 80 and older in intensive care units: a multicenter matched-cohort study. J Am Geriatr Soc. 2005;53:88–93.
15. Hamel MB, Teno JM, Goldman L, Lynn J, Davis RB, Galanos AN, Desbiens N, Connors AF Jr, Wenger N, Phillips RS. Patient age and decisions to withhold life-sustaining treatments from seriously ill, hospitalized adults. SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatment. Ann Intern Med. 1999;130:116–25.
16. Lerolle N, Trinquart L, Bornstain C, Tadié J-M, Imbert A, Diehl J-L, Fagon J-Y, Guérot E. Increased intensity of treatment and decreased mortality in elderly patients in an intensive care unit over a decade. Crit Care Med. 2010;38:59–64.
17. Moreno R, Morais P. Validation of the simplified therapeutic intervention scoring system on an independent database. Intensive Care Med. 1997;23:640–4.
18. Sznajder M, Leleu G, Buonamico G, Auvert B, Aegerter P, Merlière Y, Dutheil M, Guidet B, Le Gall JR. Estimation of direct cost and resource allocation in intensive care: correlation with Omega system. Intensive Care Med. 1998;24:582–9.
19. Reis Miranda D, Moreno R, Iapichino G. Nine equivalents of nursing manpower use score (NEMS). Intensive Care Med. 1997;23:760–5.
20. Valentin A, Ferdinande P. Recommendations on basic requirements for intensive care units: structural and organizational aspects. Intensive Care Med. 2011;37:1575–87.
21. Minne L, Eslami S, de Keizer N, de Jonge E, de Rooij SE, Abu-Hanna A. Effect of changes over time in the performance of a customized SAPS-II model on the quality of care assessment. Intensive Care Med. 2012;38:40–6.
22. Kumar A, Roberts D, Wood KE, Light B, Parrillo JE, Sharma S, Suppes R, Feinstein D, Zanotti S, Taiberg L, Gurka D, Kumar A, Cheang M. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med. 2006;34:1589–96.
23. Khouri T, Kabeshova A, Annweiler C, Mercat A, Beauchet O, Lerolle N. Amount of care per survivor in young and older patients hospitalized in intensive care unit: a retrospective study. J Gerontol A Biol Sci Med Sci. 2014;69:1291–8.
24. Le Gall JR, Klar J, Lemeshow S, Saulnier F, Alberti C, Artigas A, Teres D. The Logistic Organ Dysfunction system. A new way to assess organ dysfunction in the intensive care unit. ICU Scoring Group. JAMA. 1996;276:802–10.
25. Vincent JL, Moreno R, Takala J, Willatts S, De Mendonça A, Bruining H, Reinhart CK, Suter PM, Thijs LG. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine. Intensive Care Med. 1996;22:707–10.
26. Rapoport J, Teres D, Barnett R, Jacobs P, Shustack A, Lemeshow S, Norris C, Hamilton S. A comparison of intensive care unit utilization in Alberta and western Massachusetts. Crit Care Med. 1995;23:1336–46.
27. Woolhandler S, Himmelstein DU. Costs of care and administration at for-profit and other hospitals in the United States. N Engl J Med. 1997;336:769–74.
28. Kramer AA, Higgins TL, Zimmerman JE. Intensive care unit readmissions in U.S. hospitals: patient characteristics, risk factors, and outcomes. Crit Care Med. 2012;40:3–10.