Adipose depots, not disease-related factors, account for skeletal muscle insulin sensitivity in established and treated rheumatoid arthritis

Journal of Rheumatology

Volumn 41, Issue 10, 2014, Pages 1974-1979

  Abouassi, Hiba ^a   Tune, K Noelle ^a   Gilmore, Brian ^a   Bateman, Lori A ^a   McDaniel, Gary ^a   Muehlbauer, Michael ^b   Huebner, Janet L ^b   Hoenig, Helen M ^a   Kraus, Virginia B ^b   St Clair, E William ^a   Kraus, William E ^b   Huffman, Kim M ^b  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Body composition; Insulin resistance; Physical activity; Skeletal muscle

Indexed keywords

INTERLEUKIN 18; INTERLEUKIN 6; TUMOR NECROSIS FACTOR; ANTIRHEUMATIC AGENT;

ABDOMINAL OBESITY; ACCELEROMETRY; ADULT; ARTICLE; BODY COMPOSITION; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DISABILITY; DISEASE ACTIVITY; DISEASE DURATION; FEMALE; GLUCOSE TOLERANCE TEST; HUMAN; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPID STORAGE; MAJOR CLINICAL STUDY; MALE; OBESITY; PATIENT ASSESSMENT; PHYSICAL ACTIVITY; PREDICTION; PRIORITY JOURNAL; PROTEIN DETERMINATION; RHEUMATOID ARTHRITIS; RISK FACTOR; SKELETAL MUSCLE; THIGH ADIPOSITY; ADIPOSE TISSUE; AGED; ARTHRITIS, RHEUMATOID; BLOOD; CROSS-SECTIONAL STUDY; METABOLISM; MIDDLE AGED; PHYSIOLOGY;

ADIPOSE TISSUE; ADIPOSITY; ADULT; AGED; ANTIRHEUMATIC AGENTS; ARTHRITIS, RHEUMATOID; CROSS-SECTIONAL STUDIES; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN RESISTANCE; INTERLEUKIN-18; INTERLEUKIN-6; MALE; MIDDLE AGED; MUSCLE, SKELETAL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84954398367     PISSN: 0315162X     EISSN: 14992752     Source Type: Journal    
DOI: 10.3899/jrheum.140224     Document Type: Article

References (25)

1. Maradit-Kremers H, Crowson CS, Nicola PJ, Ballman KV, Roger VL, Jacobsen SJ, et al. Increased unrecognized coronary heart disease and sudden deaths in rheumatoid arthritis: a population-based cohort study. Arthritis Rheum 2005;52:402-11.
2. Dessein PH, Joffe BI, Stanwix AE. Editorial: should we evaluate insulin sensitivity in rheumatoid arthritis? Semin Arthritis Rheum 2005;35:5-7.
3. Chung CP, Oeser A, Solus JF, Gebretsadik T, Shintani A, Avalos I, et al. Inflammation-associated insulin resistance: differential effects in rheumatoid arthritis and systemic lupus erythematosus define potential mechanisms. Arthritis Rheum 2008;58:2105-12.
4. DeFronzo RA, Tripathy D. Skeletal muscle insulin resistance is the primary defect in type 2 diabetes. Diabetes Care 2009;32 Suppl 2:S157-63.
5. Petersen KF, Dufour S, Savage DB, Bilz S, Solomon G, Yonemitsu S, et al. The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome. Proc Natl Acad Sci U S A 2007;104:12587-94.
6. Hoes JN, van der Goes MC, van Raalte DH, van der Zijl NJ, den Uyl D, Lems WF, et al. Glucose tolerance, insulin sensitivity and beta-cell function in patients with rheumatoid arthritis treated with or without low-to-medium dose glucocorticoids. Ann Rheum Dis 2011;70:1887-94.
7. Penesova A, Radikova Z, Vlcek M, Kerlik J, Lukac J, Rovensky J, et al. Chronic inflammation and low-dose glucocorticoid effects on glucose metabolism in premenopausal females with rheumatoid arthritis free of conventional metabolic risk factors. Physiol Res 2013;62:75-83.
8. Svenson KL, Pollare T, Lithell H, Hallgren R. Impaired glucose handling in active rheumatoid arthritis: relationship to peripheral insulin resistance. Metabolism 1988;37:125-30.
9. Hallgren R, Berne C. Glucose intolerance in patients with chronic inflammatory diseases is normalized by glucocorticoids. Acta Med Scand 1983;213:351-5.
10. Rosenvinge A, Krogh-Madsen R, Baslund B, Pedersen BK. Insulin resistance in patients with rheumatoid arthritis: effect of anti-TNFalpha therapy. Scand J Rheumatol 2007;36:91-6.
11. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
12. Bruce B, Fries JF. The Stanford Health Assessment Questionnaire: a review of its history, issues, progress, and documentation. J Rheumatol 2003;30:167-78.
13. Rigler SK, Studenski S, Wallace D, Reker DM, Duncan PW. Co-morbidity adjustment for functional outcomes in community-dwelling older adults. Clin Rehabil 2002;16:420-8.
14. Taylor-Piliae RE, Haskell WL, Iribarren C, Norton LC, Mahbouba MH, Fair JM, et al. Clinical utility of the Stanford brief activity survey in men and women with early-onset coronary artery disease. J Cardiopulm Rehabil Prev 2007;27:227-32.
15. Prevoo ML, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995;38:44-8.
16. Bergman RN, Ider YZ, Bowden CR, Cobelli C. Quantitative estimation of insulin sensitivity. Am J Physiol 1979;236:E667-77.
17. Irving BA, Weltman JY, Brock DW, Davis CK, Gaesser GA, Weltman A. NIH ImageJ and Slice-O-Matic computed tomography imaging software to quantify soft tissue. Obesity 2007;15:370-6.
18. Ellis KJ. Human body composition: in vivo methods. Physiol Rev 2000;80:649-80.
19. Cohen J. Statistical power analysis for the behavioral sciences. Second ed. Hillsdale, NJ: Lawrence Erlbaum Associates Inc.; 1988.
20. Paolisso G, Valentini G, Giugliano D, Marrazzo G, Tirri R, Gallo M, et al. Evidence for peripheral impaired glucose handling in patients with connective tissue diseases. Metabolism 1991;40:902-7.
21. Martin BC, Warram JH, Krolewski AS, Bergman RN, Soeldner JS, Kahn CR. Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study. Lancet 1992;340:925-9.
22. Lorenzo C, Wagenknecht LE, Rewers MJ, Karter AJ, Bergman RN, Hanley AJ, et al. Disposition index, glucose effectiveness, and conversion to type 2 diabetes: the Insulin Resistance Atherosclerosis Study (IRAS). Diabetes Care 2010;33:2098-103.
23. Muoio DM, Neufer PD. Lipid-induced mitochondrial stress and insulin action in muscle. Cell Metab 2012;15:595-605.
24. Romacho T, Elsen M, Rohrborn D, Eckel J. Adipose tissue and its role in organ crosstalk. Acta Physiol 2014;210:733-53.
25. El-Kadre LJ, Tinoco AC. Interleukin-6 and obesity: the crosstalk between intestine, pancreas and liver. Curr Opin Clin Nutr Metab Care 2013;16:564-8.