Assessment of angiogenesis modulators in pregnant women with pre-eclampsia: a case–control study

Archives of Gynecology and Obstetrics

Volumn 293, Issue 2, 2016, Pages 369-375

  Mundim, Guilhermo Justino ^a   Paschoini, Marina Carvalho ^a   Araujo Júnior, Edward ^b   Da Silva Costa, Fabricio ^c,d   Rodrigues Júnior, Virmondes ^a  

^a FEDERAL UNIVERSITY OF TRIÂNGULO MINEIRO   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c ROYAL WOMEN'S HOSPITAL   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Angiogenesis; Cytokines; Placenta; Pre eclampsia

Indexed keywords

ANGIOGENESIS MODULATOR; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 6; PLACENTAL GROWTH FACTOR; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; IL10 PROTEIN, HUMAN; IL17A PROTEIN, HUMAN; PLACENTA PROTEIN; TUMOR NECROSIS FACTOR; VASCULOTROPIN A;

ADULT; ANGIOGENESIS; ARTICLE; BLOOD LEVEL; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GESTATION PERIOD; HUMAN; KRUSKAL WALLIS TEST; MATERNAL BLOOD; PLACENTA CIRCULATION; PREECLAMPSIA; PREGNANT WOMAN; PROSPECTIVE STUDY; PROTEINURIA; RANK SUM TEST; BLOOD; BLOOD PRESSURE; CHEMISTRY; GESTATIONAL AGE; NONPARAMETRIC TEST; PATHOPHYSIOLOGY; PLACENTA; PRE-ECLAMPSIA; PREGNANCY;

ADULT; ANGIOGENESIS MODULATING AGENTS; BLOOD PRESSURE; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GESTATIONAL AGE; HUMANS; INTERLEUKIN-10; INTERLEUKIN-17; INTERLEUKIN-6; PLACENTA; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY PROTEINS; PROSPECTIVE STUDIES; STATISTICS, NONPARAMETRIC; TUMOR NECROSIS FACTOR-ALPHA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84954388747     PISSN: 09320067     EISSN: 14320711     Source Type: Journal    
DOI: 10.1007/s00404-015-3823-x     Document Type: Article

References (37)

1. Lam C, Lim KH, Karumanchi AS (2005) Circulating angiogenic factors in phatogenesis and prediction of preeclampsia. Hypertension 46:1077–1085
2. Skjaerven R, Wilcox AJ, Lie RT (2002) The interval between pregnancies and the risk of preeclampsia. N Engl J Med 346:33–38
3. Muy-Rivera M, Vadachkoria S, Woelk GB, Qiu C, Mahomed K, Willians MA (2005) Maternal plasma VEGF, sVEGF-R1 and PlGF concentrations in preeclampitic and normotensive pregnant Zimbabwean women. Physiol Res 54:611–622
4. Hladunewich M, Karumanchi SA, Lafayette R (2007) Pathophysiology of the clinical manifestations pre-eclampsia. Clin J Am Soc Nephrol 2:543–549
5. Carmeliet P (2004) Manipulating angiogenesis in medicine. J Intern Med 255:538–561
6. Romero R, Nien JK, Espinoza J, Todem D, Fu W, Chung H et al (2008) A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble VEGF receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small-gestational-age neonate. J Matern Fetal Neonatal Med 21:9–23
7. Yong BC, Levine RJ, Karumanchi SA (2010) Pathogenesis of preeclampsia. Annu Rev Pathol 5:173–192
8. Qiu Y, Hoareau-Aveilla C, Oltean S, Harper SJ, Bates DO (2009) The anti-angiogenic isoforms of VEGF in health and disease. Biochem Soc Trans 37:1207–1213
9. Sandrim VC, Palei ACT, Eleuterio N, Tanus-Santos JE, Cavalli RC (2015) Antihypertensive therapy in preeclampsia is not modulated by VEGF polymorphisms. Arch Gynecol Obstet 291:799–803
10. Silva VRS, Soardi FC, Tanaka SCSV, Silva-Greco RL, Paschoini MC, Balarin AS (2015) Investigation of polymorphisms in pre-eclampsia related genes VEGF and IL1A. Arch Gynecol Obstet 291:1029–1035
11. Ghosh SK, Raheja S, Tuli A, Raghunandan C, Agarwal S (2013) Is serum placental growth factor more effective as a biomarker in predicting early onset preeclampsia in early second trimester than in first trimester of pregnancy? Arch Gynecol Obstet 287:865–873
12. Redman CW, Sargent IL (2010) Immunology of pre-eclampsia. Am J Reprod Immunol 63:534–543
13. Jovanovic M, Kovacevic T, Stefanoska I, Vicovac L (2010) The effect of IL-6 on the trophoblast cell line HTR-8/SVNEO. Arch Biol Sci 62:531–538
14. Artunc-Ulkumen B, Guvenc y, Goker A, Gozukara C (2015) Maternal serum S100-B, PAPP-A and IL-6 in severe preeclampsia. Arch Gynecol Obstet [ahead of print]
15. Ferrão MH, Pereira AC, Gersgorin HC, Paula TA, Corrêa RR (2006) Castro EC [Treatment effectiveness of hypertension during pregnancy]. Rev Assoc Med Bras 52:390–396
16. Santner-Nanan B, Peek MJ, Khanam R, Richarts L, Zhu E, Groth BF et al (2009) Systemic increase in the ratio between Foxp3 + and IL-17-producing CD4 + T cells in healthy pregnancy but not in preeclampsia. J Immnuol 183:7023–7030
17. Nakashima A, Ito M, Yoneda S, Shiozaki A, Hidaka T, Saito S (2010) Circulating and decidual TH17 cell levels in healthy pregnancy. Am J Reprod Immunol 63:104–109
18. Sibai BM, Dekker GA, Kuplerminc M (2005) Preeclampsia. Lancet 365:785–799
19. Grill S, Rusterholz C, Zanetti-Dasllenbach R, Tercanli S, Holzgreve W, Hahn S et al (2009) Potential markers of preeclampsia–a review. Reprod Biol Endocrinol 70:1–14
20. (2000) Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. Am J Obstet Gynecol 183:S1–S22
21. Sibai BM (1998) Prevention of preeclampsia: a big disappointment. Am J Obstet Gynecol 179:1275–1278
22. Lynch A, Salmon JE (2010) Dysregulated complement activation as a common pathway of injury in preeclampsia and other pregnancy complications. Placenta 31:561–567
23. Lapaire O, Shennan A, Stepan H (2010) The preeclampsia biomakers solubles fms-like tyrosine kinase-1 and placental growth factor: current knowledge, clinical implications and future application. Eur J Obstet Gynecol Reprod Biol 151:122–129
24. Holston AM, Qian C, Yu KF, Epstein FH, Karumanchi AS, Levine RJ (2009) Circulating factors in gestational proteinuria without hypertension. Am J Obstet Gynecol 200:392.e1–e10
25. Sharkey AM, Cooper JC, Balmforth JR, McLaren J, Clarck DE, Charnok-Jones DS et al (1996) Maternal plasma levels of vascular endothelial growth factor in normotensive pregnancies and in pregnancies complicated by preeclampsia. Eur J Clin Invest 26:1182–1185
26. Bersinger NA, Odegard RA (2005) Serum levels of macrophage colony stimulating vascular endothelial, and placenta growth factor in relation to later clinical onset of pre-eclampsia and small-for-gestational age birth. Am J Reprod Immunol 54:77–83
27. Liu F, Guo J, Tian T, Wang H, Dong F, Huang H et al (2011) Plancental trophoblasts shifted Th1/Th2 balance toward Th2 and inhibited Th17 immunity at fetomaternal interface. APMIS 119:597–604
28. Saito S (2010) TH17 cells and regulatory T cells: new light on pathophysiology of preeclampsia. Immunol Cell Biol 88:615–617
29. Kalkunte S, Nevers T, Noris WE, Sharma S (2011) Vascular IL-10: a protective role in preeclampsia. J Reprod Immunol 88:165–169
30. Lewis DF, Canzoneri BJ, Wang Y (2009) Maternum circulating TNF- α levels are highly correlated with IL-10 levels, but not IL-6 and IL-8 levels, in women with pre-eclampsia. Am J Reprod Immunol 62:269–274
31. Wu MY, Chen HF, Chen SU, Chao KH, Yang YS, Ho HN (2001) Increase in the production of interleukin-10 early after implantation is related to the success of pregnancy. Am J Reprod Immunol 46:386–392
32. Vitoratos N, Economou E, Iavazzo C, Panoulis K, Creatsas G (2010) Maternal serum levels of TNF-alpha and IL-6 long after delivery in preeclamptic and normotensive pregnant women. Mediators Inflamm 2010:908649
33. Amash A, Holcberg G, Sheiner E, Huleihel M (2010) Magnesium sulfate normalizes placental interleukin-6 secretion in preeclampsia. J Interferon Cytokine Res 30:683–690
34. Roudsari FV, Ayati S, Ayatollahi H, Esmaeily H, Hasanzadeh M, Shahabian M et al (2009) Comparison of maternal serum Tumor Necrosis Factor-alpha (TNFα) in severe and mild preeclampsia versus normal pregnancy. Iran J Reprod Med 7:153–156
35. Lamarca BD, Ryan MJ, Granger JP (2007) Pathophysiology during preeclampsia. Curr Hypertens Rev 9:480–485
36. Lockwood CJ, Yen C, Basar M, Kayisli UA, Martel M, Buhimschi I et al (2008) Preeclampsia-related inflammatory cytokines regulate interleukin-6 in human decidual cells. Am J Pathol 172:1571–1579
37. Szarka A, Rigó-Junior J, Lázar L, Bekö G, Molvarec A (2010) Circulation cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array. BMC Immunol 11:1–9