Broad-range TRP channel inhibitors (2-APB, flufenamic acid, SKF-96365) affect differently contraction of resistance and conduit femoral arteries of rat

European Journal of Pharmacology

Volumn 765, Issue , 2015, Pages 533-540

  Bencze, Michal ^a,b   Behuliak, Michal ^a   Vavřínová, Anna ^a,b   Zicha, Josef ^a  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

Author keywords

2 APB; Femoral artery; Flufenamic acid; SKF 96365; TRP channel; Vascular contraction

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; 15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 2 AMINOETHOXYDIPHENYLBORANE; FLUFENAMIC ACID; NIFEDIPINE; PHENYLEPHRINE; POTASSIUM ION; SODIUM ION; 1-(2-(3-(4-METHOXYPHENYL)PROPOXY)-4-METHOXYPHENYLETHYL)-1H-IMIDAZOLE; 2-AMINOETHOXYDIPHENYL BORATE; BORON DERIVATIVE; IMIDAZOLE DERIVATIVE; TRANSIENT RECEPTOR POTENTIAL CHANNEL;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTERY RESISTANCE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; EXTRACELLULAR SPACE; FEMORAL ARTERY; GENE EXPRESSION; INHIBITION KINETICS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; ANTAGONISTS AND INHIBITORS; DOSE RESPONSE; DRUG EFFECTS; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION; WISTAR RAT;

ANIMALS; BORON COMPOUNDS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMORAL ARTERY; FLUFENAMIC ACID; IMIDAZOLES; MALE; MUSCLE, SMOOTH, VASCULAR; ORGAN CULTURE TECHNIQUES; RATS; RATS, WISTAR; TRANSIENT RECEPTOR POTENTIAL CHANNELS; VASOCONSTRICTION;

EID: 84954357407     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.09.014     Document Type: Article

References (30)

1. C.L. Andersen, J.L. Jensen, T.F. Ørntoft Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets Cancer Res. 64 2004 5245 5250
2. D.J. Beech Characteristics of transient receptor potential canonical calcium-permeable channels and their relevance to vascular physiology and disease Circ. J. 77 2013 570 579
3. G. Boulay, X. Zhu, M. Peyton, M. Jiang, R. Hurst, E. Stefani, L. Birnbaumer Cloning and expression of a novel mammalian homolog of Drosophila transient receptor potential (Trp) involved in calcium entry secondary to activation of receptors coupled by the Gq class of G protein J. Biol. Chem. 272 1997 29672 29680
4. D.E. Clapham TRP channels as cellular sensors Nature 426 2003 517 524
5. S. Earley, J.E. Brayden Transient receptor potential channels in the vasculature Physiol. Rev. 95 2015 645 690
6. J.C. Gonzalez-Cobos, M. Trebak TRPC channels in smooth muscle cells Front. Biosci. 15 2010 1023 1039
7. C. Guibert, T. Ducret, J.P. Savineau Voltage-independent calcium influx in smooth muscle Prog. Biophys. Mol. Biol. 98 2008 10 23
8. R. Guinamard, C. Simard, C. Del Negro Flufenamic acid as an ion channel modulator Pharmacol. Ther. 138 2013 272 284
9. C. Harteneck, M. Gollasch Pharmacological modulation of diacylglycerol-sensitive TRPC3/6/7 channels Curr. Pharm. Biotechnol. 12 2011 35 41
10. 2+-permeable cation channel Circ. Res. 88 2001 325 332
11. R. Inoue, L.J. Jensen, J. Shi, H. Morita, M. Nishida, A. Honda, Y. Ito Transient receptor potential channels in cardiovascular function and disease Circ. Res. 99 2006 119 131
12. H. Jiang, B. Zeng, G.L. Chen, D. Bot, S. Eastmond, S.E. Elsenussi, S.L. Atkin, A.N. Boa, S.Z. Xu Effect of non-steroidal anti-inflammatory drugs and new fenamate analogues on TRPC4 and TRPC5 channels Biochem. Pharmacol. 83 2012 923 931
13. L. Lemonnier, M. Trebak, J.W. Putney Jr. Complex regulation of the TRPC3, 6 and 7 channel subfamily by diacylglycerol and phosphatidylinositol-4,5-bisphosphate Cell Calcium 43 2008 506 514
14. J.P. Lievremont, G.S. Bird, J.W. Putney Jr. Mechanism of inhibition of TRPC cation channels by 2-aminoethoxydiphenylborane Mol. Pharmacol. 68 2005 758 762
15. S.H. Lindsey, R.M. Tribe, E. Songu-Mize Cyclic stretch decreases TRPC4 protein and capacitative calcium entry in rat vascular smooth muscle cells Life Sci. 83 2008 29 34
16. D. Liu, D. Yang, H. He, X. Chen, T. Cao, X. Feng, L. Ma, Z. Luo, L. Wang, Z. Yan, Z. Zhu, M. Tepel Increased transient receptor potential canonical type 3 channels in vasculature from hypertensive rats Hypertension 53 2009 70 76
17. J.E. Merritt, W.P. Armstrong, C.D. Benham, T.J. Hallam, R. Jacob, A. Jaxa-Chamiec, B.K. Leigh, S.A. McCarthy, K.E. Moores, T.J. Rink SK&F 96365, a novel inhibitor of receptor-mediated calcium entry Biochem. J. 271 1990 515 522
18. M.G. Rae, J. Hilton, J. Sharkey Putative TRP channel antagonists, SKF 96365, flufenamic acid and 2-APB, are non-competitive antagonists at recombinant human α1β2γ2 GABA(A) receptors Neurochem. Int. 60 2012 543 554
19. J.M. Ruijter, C. Ramakers, W.M. Hoogaars, Y. Karlen, O. Bakker, M.J. Van den Hoff, A.F. Moorman Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data Nucleic Acids Res. 37 2009 e45
20. 2+ responses to noradrenaline: possible role of TRPC channels Acta Physiol. 200 2010 265 278
21. S.G. Shlykov, M. Yang, J.L. Alcorn, B.M. Sanborn Capacitative cation entry in human myometrial cells and augmentation by hTrpC3 overexpression Biol. Reprod. 69 2003 647 655
22. 2+ signal generation in A7r5 smooth muscle cells J. Biol. Chem. 280 2005 39786 39794
23. K. Tai, M.C. Hamaide, H. Debaix, P. Gailly, M. Wibo, N. Morel Agonist-evoked calcium entry in vascular smooth muscle cells requires IP3 receptor-mediated activation of TRPC1 Eur. J. Pharmacol. 583 2008 135 147
24. M. Tosun, R.J. Paul, R.M. Rapoport Role of extracellular Ca++ influx via l-type and non-l-type Ca++ channels in thromboxane A2 receptor-mediated contraction in rat aorta J. Pharmacol. Exp. Ther. 284 1998 921 928
25. 2+-activated cation channels TRPM4 and TRPM5 from mice Cell Calcium 37 2005 267 278
26. G. Vazquez, B.J. Wedel, O. Aziz, M. Trebak, J.W. Putney Jr. The mammalian TRPC cation channels Biochim. Biophys. Acta 1742 2004 21 36
27. H. Watanabe, M. Murakami, T. Ohba, Y. Takahashi, H. Ito TRP channel and cardiovascular disease Pharmacol. Ther. 118 2008 337 351
28. R.C. Webb Smooth muscle contraction and relaxation Adv. Physiol. Educ. 27 2003 201 206
29. S.Z. Xu, F. Zeng, G. Boulay, C. Grimm, C. Harteneck, D.J. Beech Block of TRPC5 channels by 2-aminoethoxydiphenyl borate: a differential, extracellular and voltage-dependent effect Br. J. Pharmacol. 145 2005 405 414
30. S.Z. Xu, G. Boulay, R. Flemming, D.J. Beech E3-targeted anti-TRPC5 antibody inhibits store-operated calcium entry in freshly isolated pial arterioles Am. J. Physiol. Heart Circ. Physiol. 291 2006 H2653 H2659