메뉴 건너뛰기




Volumn 57, Issue 1, 2016, Pages 92-98

High serum concentration of L-kynurenine predicts unfavorable outcomes in patients with acute myeloid leukemia

Author keywords

3 dioxygenase; acute myeloid leukemia (AML); immunological tolerance; indoleamine 2; L kynurenine; L tryptophan catabolism; prognostic factor

Indexed keywords

ANTHRACYCLINE; CYTARABINE; DAUNORUBICIN; ETOPOSIDE; GEMTUZUMAB OZOGAMICIN; IDARUBICIN; KYNURENINE; LACTATE DEHYDROGENASE; TUMOR MARKER;

EID: 84954287348     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2015.1041388     Document Type: Article
Times cited : (35)

References (48)
  • 1
    • 33646404606 scopus 로고    scopus 로고
    • Age and acute myeloid leukemia
    • Appelbaum FR, Gundacker H, Head DR, et al. Age and acute myeloid leukemia. Blood 2006;107:3481-3485.
    • (2006) Blood , vol.107 , pp. 3481-3485
    • Appelbaum, F.R.1    Gundacker, H.2    Head, D.R.3
  • 2
    • 0023879484 scopus 로고
    • Acute myeloblastic leukemia with hyperleukocytosis: Risk factors for early mortality in induction
    • Ventura GJ, Hester JP, Smith TL, Keating MJ. Acute myeloblastic leukemia with hyperleukocytosis: risk factors for early mortality in induction. Am J Hematol 1988;27:34-37.
    • (1988) Am J Hematol , vol.27 , pp. 34-37
    • Ventura, G.J.1    Hester, J.P.2    Smith, T.L.3    Keating, M.J.4
  • 3
    • 0023413292 scopus 로고
    • Hyperleukocytosis in adult acute nonlymphocytic leukemia: Impact on remission rate and duration, and survival
    • Dutcher JP, Schiffer CA, Wiernik PH. Hyperleukocytosis in adult acute nonlymphocytic leukemia: impact on remission rate and duration, and survival. J Clin Oncol 1987;5:1364-1372.
    • (1987) J Clin Oncol , vol.5 , pp. 1364-1372
    • Dutcher, J.P.1    Schiffer, C.A.2    Wiernik, P.H.3
  • 4
    • 33747729551 scopus 로고    scopus 로고
    • Leukocyte count as a predictor of death during remission induction in acute myeloid leukemia
    • Greenwood MJ, Seftel MD, Richardson C, et al. Leukocyte count as a predictor of death during remission induction in acute myeloid leukemia. Leuk Lymphoma 2006;47:1245-1252.
    • (2006) Leuk Lymphoma , vol.47 , pp. 1245-1252
    • Greenwood, M.J.1    Seftel, M.D.2    Richardson, C.3
  • 5
    • 48749123878 scopus 로고    scopus 로고
    • Prognostic implications of gene mutations in acute myeloid leukemia with normal cytogenetics
    • Gaidzik V, Döhner K. Prognostic implications of gene mutations in acute myeloid leukemia with normal cytogenetics. Semin Oncol 2008;35:346-355.
    • (2008) Semin Oncol , vol.35 , pp. 346-355
    • Gaidzik, V.1    Döhner, K.2
  • 7
    • 33846230449 scopus 로고    scopus 로고
    • Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: Are we ready for a prognostically prioritized molecular classification?
    • Mrózek K, Marcucci G, Paschka P, et al. Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification? Blood 2007;109:431-448.
    • (2007) Blood , vol.109 , pp. 431-448
    • Mrózek, K.1    Marcucci, G.2    Paschka, P.3
  • 8
    • 0033215041 scopus 로고    scopus 로고
    • Tryptophan catabolism and T-cell tolerance: Immunosuppression by starvation?
    • Mellor AL, Munn DH. Tryptophan catabolism and T-cell tolerance: immunosuppression by starvation? Immunol Today 1999;20:469-473.
    • (1999) Immunol Today , vol.20 , pp. 469-473
    • Mellor, A.L.1    Munn, D.H.2
  • 9
    • 0033519278 scopus 로고    scopus 로고
    • Inhibition of T cell proliferation by macrophage tryptophan catabolism
    • Munn DH, Shafizadeh E, Attwood JT, et al. Inhibition of T cell proliferation by macrophage tryptophan catabolism. J Exp Med 1999;189:1363-1372.
    • (1999) J Exp Med , vol.189 , pp. 1363-1372
    • Munn, D.H.1    Shafizadeh, E.2    Attwood, J.T.3
  • 10
    • 0024495089 scopus 로고
    • Role of tryptophan degradation in respiratory burst-independent antimicrobial activity of gamma interferon-stimulated human macrophages
    • Murray HW, Szuro-Sudol A, Wellner D, et al. Role of tryptophan degradation in respiratory burst-independent antimicrobial activity of gamma interferon-stimulated human macrophages. Infect Immun 1989;57:845-849.
    • (1989) Infect Immun , vol.57 , pp. 845-849
    • Murray, H.W.1    Szuro-Sudol, A.2    Wellner, D.3
  • 11
    • 0034850590 scopus 로고    scopus 로고
    • Lipopolysaccharide induction of indoleamine 2, 3-dioxygenase is mediated dominantly by an IFNgamma-independent mechanism
    • Fujigaki S, Saito K, Sekikawa K, et al. Lipopolysaccharide induction of indoleamine 2, 3-dioxygenase is mediated dominantly by an IFNgamma-independent mechanism. Eur J Immunol 2001;31:2313-2318.
    • (2001) Eur J Immunol , vol.31 , pp. 2313-2318
    • Fujigaki, S.1    Saito, K.2    Sekikawa, K.3
  • 12
    • 33745654304 scopus 로고    scopus 로고
    • The signal transducer and activator of transcription 1alpha and interferon regulatory factor 1 are not essential for the induction of indoleamine 2, 3-dioxygenase by lipopolysaccharide: Involvement of p38 mitogen-activated protein kinase and nuclear factor-kappaB pathways, and synergistic effect of several proinflammatory cytokines
    • Fujigaki H, Saito K, Fujigaki S, et al. The signal transducer and activator of transcription 1alpha and interferon regulatory factor 1 are not essential for the induction of indoleamine 2, 3-dioxygenase by lipopolysaccharide: involvement of p38 mitogen-activated protein kinase and nuclear factor-kappaB pathways, and synergistic effect of several proinflammatory cytokines. J Biochem 2006;139:655-662.
    • (2006) J Biochem , vol.139 , pp. 655-662
    • Fujigaki, H.1    Saito, K.2    Fujigaki, S.3
  • 13
    • 0037136328 scopus 로고    scopus 로고
    • Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2, 3-dioxygenase
    • Frumento G, Rotondo R, Tonetti M, et al. Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2, 3-dioxygenase. J Exp Med 2002;196:459-468.
    • (2002) J Exp Med , vol.196 , pp. 459-468
    • Frumento, G.1    Rotondo, R.2    Tonetti, M.3
  • 14
    • 0037024439 scopus 로고    scopus 로고
    • Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer
    • Huang A, Fuchs D, Widner B, et al. Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer. Br J Cancer 2002;86:1691-1696.
    • (2002) Br J Cancer , vol.86 , pp. 1691-1696
    • Huang, A.1    Fuchs, D.2    Widner, B.3
  • 15
    • 77949456437 scopus 로고    scopus 로고
    • Serum concentration of L-kynurenine predicts the clinical outcome of patients with diffuse large B-cell lymphoma treated with R-CHOP
    • Yoshikawa T, Hara T, Tsurumi H, et al. Serum concentration of L-kynurenine predicts the clinical outcome of patients with diffuse large B-cell lymphoma treated with R-CHOP. Eur J Haematol 2010;84:304-309.
    • (2010) Eur J Haematol , vol.84 , pp. 304-309
    • Yoshikawa, T.1    Hara, T.2    Tsurumi, H.3
  • 16
    • 79955928670 scopus 로고    scopus 로고
    • Indoleamine 2, 3-dioxygenase in tumor tissue indicates prognosis in patients with diffuse large B-cell lymphoma treated with R-CHOP
    • Ninomiya S, Hara T, Tsurumi H, et al. Indoleamine 2, 3-dioxygenase in tumor tissue indicates prognosis in patients with diffuse large B-cell lymphoma treated with R-CHOP. Ann Hematol 2011;90:409-416.
    • (2011) Ann Hematol , vol.90 , pp. 409-416
    • Ninomiya, S.1    Hara, T.2    Tsurumi, H.3
  • 17
    • 84861350333 scopus 로고    scopus 로고
    • Indoleamine 2, 3-dioxygenase expression and serum kynurenine concentrations in patients with diffuse large B-cell lymphoma
    • Ninomiya S, Hara T, Tsurumi H, et al. Indoleamine 2, 3-dioxygenase expression and serum kynurenine concentrations in patients with diffuse large B-cell lymphoma. Leuk Lymphoma 2012;53:1143-1145.
    • (2012) Leuk Lymphoma , vol.53 , pp. 1143-1145
    • Ninomiya, S.1    Hara, T.2    Tsurumi, H.3
  • 18
    • 84954298195 scopus 로고    scopus 로고
    • Expression of indoleamine 2, 3-dioxygenase in leukemic cells indicates an unfavorable prognosis in patients with acute myeloid leukemia and intermediate-risk cytogenetics
    • In press
    • Fukuno K, Hara T, Tsurumi H, et al. Expression of indoleamine 2, 3-dioxygenase in leukemic cells indicates an unfavorable prognosis in patients with acute myeloid leukemia and intermediate-risk cytogenetics. Leuk Lymphoma In press
    • Leuk Lymphoma
    • Fukuno, K.1    Hara, T.2    Tsurumi, H.3
  • 19
    • 67649431530 scopus 로고    scopus 로고
    • Acute myeloid leukaemia with myelodysplasia-related changes
    • In: Swerdlow S, Campo E, Harris NL, editors. 4th ed. Geneva: World Health Organization
    • Arber DA, Brunning RD, Orazi A, et al. Acute myeloid leukaemia with myelodysplasia-related changes. In: Swerdlow S, Campo E, Harris NL, editors. WHO classification of tumors of hematopoietic and lymphoid tissues. 4th ed. Geneva: World Health Organization; 2008. Pp. 124-126.
    • (2008) WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues , pp. 124-126
    • Arber, D.A.1    Brunning, R.D.2    Orazi, A.3
  • 20
    • 0022135739 scopus 로고
    • Proposed revised criteria for the classification of acute myeloid leukaemia
    • A report of the French-American-British Cooperative Group
    • Bennett JM, Catovsky D, Daniel MT, et al. Proposed revised criteria for the classification of acute myeloid leukaemia. A report of the French-American-British Cooperative Group. Ann Intern Med 1985;103:620-625.
    • (1985) Ann Intern Med , vol.103 , pp. 620-625
    • Bennett, J.M.1    Catovsky, D.2    Daniel, M.T.3
  • 21
    • 0032188805 scopus 로고    scopus 로고
    • The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1, 612 patients entered into the MRC AML 10 trial
    • The Medical Research Council Adult and Children's Leukaemia Working Parties
    • Grimwade D, Walker H, Oliver F, et al. The importance of diagnostic cytogenetics on outcome in AML: analysis of 1, 612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. Blood 1998;92:2322-2333.
    • (1998) Blood , vol.92 , pp. 2322-2333
    • Grimwade, D.1    Walker, H.2    Oliver, F.3
  • 22
    • 0032532675 scopus 로고    scopus 로고
    • Species differences in L-tryptophan-kynurenine pathway metabolism: Quantification of anthranilic acid and its related enzymes
    • Fujigaki S, Saito K, Takemura M, et al. Species differences in L-tryptophan-kynurenine pathway metabolism: quantification of anthranilic acid and its related enzymes. Arch Biochem Biophys 1998;358:329-335.
    • (1998) Arch Biochem Biophys , vol.358 , pp. 329-335
    • Fujigaki, S.1    Saito, K.2    Takemura, M.3
  • 23
    • 0037217515 scopus 로고    scopus 로고
    • Cytogenetic heterogeneity of acute myeloid leukaemia (AML) with trilineage dysplasia: Japan Adult Leukaemia Study Group-AML 92 study
    • Miyazaki Y, Kuriyama K, Miyawaki S, et al. Cytogenetic heterogeneity of acute myeloid leukaemia (AML) with trilineage dysplasia: Japan Adult Leukaemia Study Group-AML 92 study. Br J Haematol 2003;120:56-62.
    • (2003) Br J Haematol , vol.120 , pp. 56-62
    • Miyazaki, Y.1    Kuriyama, K.2    Miyawaki, S.3
  • 24
    • 34250703743 scopus 로고    scopus 로고
    • Therapeutic strategy of untreated de novo acute myeloid leukemia in the elderly: The efficacy of continuous drip infusion with low dose cytarabine and etoposide
    • Tsurumi H, Kanemura N, Hara T, et al. Therapeutic strategy of untreated de novo acute myeloid leukemia in the elderly: the efficacy of continuous drip infusion with low dose cytarabine and etoposide. J Cancer Res Clin Oncol 2007;133:547-553.
    • (2007) J Cancer Res Clin Oncol , vol.133 , pp. 547-553
    • Tsurumi, H.1    Kanemura, N.2    Hara, T.3
  • 25
    • 41349102596 scopus 로고    scopus 로고
    • Continuous drip infusion of low dose cytarabine and etoposide with granulocyte colonystimulating factor for elderly patients with acute myeloid leukaemia ineligible for intensive chemotherapy
    • Kanemura N, Tsurumi H, Kasahara S, et al. Continuous drip infusion of low dose cytarabine and etoposide with granulocyte colonystimulating factor for elderly patients with acute myeloid leukaemia ineligible for intensive chemotherapy. Hematol Oncol 2008;26:33-38.
    • (2008) Hematol Oncol , vol.26 , pp. 33-38
    • Kanemura, N.1    Tsurumi, H.2    Kasahara, S.3
  • 26
    • 1542753559 scopus 로고    scopus 로고
    • Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia
    • Cheson BD, Bennett JM, Kopecky KJ, et al. Revised recommendations of the International Working Group for Diagnosis, Standardization of Response Criteria, Treatment Outcomes, and Reporting Standards for Therapeutic Trials in Acute Myeloid Leukemia. J Clin Oncol 2003;21:4642-4649.
    • (2003) J Clin Oncol , vol.21 , pp. 4642-4649
    • Cheson, B.D.1    Bennett, J.M.2    Kopecky, K.J.3
  • 27
    • 0034672269 scopus 로고    scopus 로고
    • Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: A Southwest Oncology Group/Eastern Cooperative Oncology Group Study
    • Slovak ML, Kopecky KJ, Cassileth PA, et al. Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group Study. Blood 2000;96:4075-4083.
    • (2000) Blood , vol.96 , pp. 4075-4083
    • Slovak, M.L.1    Kopecky, K.J.2    Cassileth, P.A.3
  • 28
    • 0142137237 scopus 로고    scopus 로고
    • Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2, 3-dioxygenase
    • Uyttenhove C, Pilotte L, Théate I, et al. Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2, 3-dioxygenase. Nat Med 2003;9:1269-1274.
    • (2003) Nat Med , vol.9 , pp. 1269-1274
    • Uyttenhove, C.1    Pilotte, L.2    Théate, I.3
  • 29
    • 33750699056 scopus 로고    scopus 로고
    • The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46-and NKG2D-activating receptors and regulates NK-cell function
    • Della Chiesa M, Carlomagno S, Frumento G, et al. The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46-and NKG2D-activating receptors and regulates NK-cell function. Blood 2006;108:4118-4125.
    • (2006) Blood , vol.108 , pp. 4118-4125
    • Della Chiesa, M.1    Carlomagno, S.2    Frumento, G.3
  • 30
    • 33845246900 scopus 로고    scopus 로고
    • Indoleamine 2, 3-dioxygenase is a novel prognostic indicator for endometrial cancer
    • Ino K, Yoshida N, Kajiyama H, et al. Indoleamine 2, 3-dioxygenase is a novel prognostic indicator for endometrial cancer. Br J Cancer 2006;95:1555-1561.
    • (2006) Br J Cancer , vol.95 , pp. 1555-1561
    • Ino, K.1    Yoshida, N.2    Kajiyama, H.3
  • 31
    • 34548024195 scopus 로고    scopus 로고
    • Increased synthesis of indoleamine-2, 3-dioxygenase protein is positively associated with impaired survival in patients with serous-type, but not with other types of, ovarian cancer
    • Takao M, Okamoto A, Nikaido T, et al. Increased synthesis of indoleamine-2, 3-dioxygenase protein is positively associated with impaired survival in patients with serous-type, but not with other types of, ovarian cancer. Oncol Rep 2007;17:1333-1339.
    • (2007) Oncol Rep , vol.17 , pp. 1333-1339
    • Takao, M.1    Okamoto, A.2    Nikaido, T.3
  • 32
    • 0029147379 scopus 로고
    • Interleukin-1 enhances indoleamine 2, 3-dioxygenase activity by increasing specific mRNA expression in human mononuclear phagocytes
    • Hu B, Hissong BD, Carlin JM. Interleukin-1 enhances indoleamine 2, 3-dioxygenase activity by increasing specific mRNA expression in human mononuclear phagocytes. J Interferon Cytokine Res 1995;15:617-624.
    • (1995) J Interferon Cytokine Res , vol.15 , pp. 617-624
    • Hu, B.1    Hissong, B.D.2    Carlin, J.M.3
  • 33
    • 0030813497 scopus 로고    scopus 로고
    • Potentiation of interferon-induced indoleamine 2, 3-dioxygenase mRNA in human mononuclear phagocytes by lipopolysaccharide and interleukin-1
    • Hissong BD, Carlin JM. Potentiation of interferon-induced indoleamine 2, 3-dioxygenase mRNA in human mononuclear phagocytes by lipopolysaccharide and interleukin-1. J Interferon Cytokine Res 1997;17:387-393.
    • (1997) J Interferon Cytokine Res , vol.17 , pp. 387-393
    • Hissong, B.D.1    Carlin, J.M.2
  • 34
    • 0034015314 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha and lipopolysaccharide enhance interferon-induced antichlamydial indoleamine dioxygenase activity independently
    • Currier AR, Ziegler MH, Riley MM, et al. Tumor necrosis factor-alpha and lipopolysaccharide enhance interferon-induced antichlamydial indoleamine dioxygenase activity independently. J Interferon Cytokine Res 2000;20:369-376.
    • (2000) J Interferon Cytokine Res , vol.20 , pp. 369-376
    • Currier, A.R.1    Ziegler, M.H.2    Riley, M.M.3
  • 35
    • 0033949638 scopus 로고    scopus 로고
    • Transcriptional activation of indoleamine dioxygenase by interleukin 1 and tumor necrosis factor alpha in interferon-treated epithelial cells
    • Babcock TA, Carlin JM. Transcriptional activation of indoleamine dioxygenase by interleukin 1 and tumor necrosis factor alpha in interferon-treated epithelial cells. Cytokine 2000;12: 588-594.
    • (2000) Cytokine , vol.12 , pp. 588-594
    • Babcock, T.A.1    Carlin, J.M.2
  • 36
    • 0042884203 scopus 로고    scopus 로고
    • Synergistic transcriptional activation of indoleamine dioxygenase by IFN-gamma and tumor necrosis factor-alpha
    • Robinson CM, Shirey KA, Carlin JM. Synergistic transcriptional activation of indoleamine dioxygenase by IFN-gamma and tumor necrosis factor-alpha. J Interferon Cytokine Res 2003;23:413-421.
    • (2003) J Interferon Cytokine Res , vol.23 , pp. 413-421
    • Robinson, C.M.1    Shirey, K.A.2    Carlin, J.M.3
  • 37
    • 0029041430 scopus 로고
    • Involvement of two regulatory elements in interferon-gamma-regulated expression of human indoleamine 2, 3-dioxygenase gene
    • Chon SY, Hassanain HH, Pine R, et al. Involvement of two regulatory elements in interferon-gamma-regulated expression of human indoleamine 2, 3-dioxygenase gene. J Interferon Cytokine Res 1995;15:517-526.
    • (1995) J Interferon Cytokine Res , vol.15 , pp. 517-526
    • Chon, S.Y.1    Hassanain, H.H.2    Pine, R.3
  • 38
    • 0030035226 scopus 로고    scopus 로고
    • Cooperative role of interferon regulatory factor 1 and p91 (STAT1) response elements in interferongamma-inducible expression of human indoleamine 2, 3-dioxygenase gene
    • Chon SY, Hassanain HH, Gupta SL. Cooperative role of interferon regulatory factor 1 and p91 (STAT1) response elements in interferongamma-inducible expression of human indoleamine 2, 3-dioxygenase gene. J Biol Chem 1996;271:17247-17252.
    • (1996) J Biol Chem , vol.271 , pp. 17247-17252
    • Chon, S.Y.1    Hassanain, H.H.2    Gupta, S.L.3
  • 39
    • 12144251098 scopus 로고    scopus 로고
    • The role of IFN-gamma and TNF-alpha-responsive regulatory elements in the synergistic induction of indoleamine dioxygenase
    • Robinson CM, Hale PT, Carlin JM. The role of IFN-gamma and TNF-alpha-responsive regulatory elements in the synergistic induction of indoleamine dioxygenase. J Interferon Cytokine Res 2005;25:20-30.
    • (2005) J Interferon Cytokine Res , vol.25 , pp. 20-30
    • Robinson, C.M.1    Hale, P.T.2    Carlin, J.M.3
  • 40
    • 84886945280 scopus 로고    scopus 로고
    • Indoleamine 2, 3-dioxygenase activity and clinical outcome following induction chemotherapy and concurrent chemoradiation in Stage III non-small cell lung cancer
    • Creelan BC, Antonia S, Bepler G, et al. Indoleamine 2, 3-dioxygenase activity and clinical outcome following induction chemotherapy and concurrent chemoradiation in Stage III non-small cell lung cancer. Oncoimmunology 2013;2:e23428.
    • (2013) Oncoimmunology , vol.2 , pp. e23428
    • Creelan, B.C.1    Antonia, S.2    Bepler, G.3
  • 41
    • 4043092238 scopus 로고    scopus 로고
    • Expression of indoleamine 2, 3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes
    • Munn DH, Sharma MD, Hou D, et al. Expression of indoleamine 2, 3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. J Clin Invest 2004;114:280-290.
    • (2004) J Clin Invest , vol.114 , pp. 280-290
    • Munn, D.H.1    Sharma, M.D.2    Hou, D.3
  • 42
    • 16244408626 scopus 로고    scopus 로고
    • Inhibition of indoleamine 2, 3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy
    • Muller AJ, DuHadaway JB, Donover PS, et al. Inhibition of indoleamine 2, 3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy. Nat Med 2005;11:312-319.
    • (2005) Nat Med , vol.11 , pp. 312-319
    • Muller, A.J.1    DuHadaway, J.B.2    Donover, P.S.3
  • 43
    • 58149335435 scopus 로고    scopus 로고
    • Overexpression of indoleamine 2, 3-dioxygenase in human endometrial carcinoma cells induces rapid tumor growth in a mouse xenograft model
    • Yoshida N, Ino K, Ishida Y, et al. Overexpression of indoleamine 2, 3-dioxygenase in human endometrial carcinoma cells induces rapid tumor growth in a mouse xenograft model. Clin Cancer Res 2008;14:7251-7259.
    • (2008) Clin Cancer Res , vol.14 , pp. 7251-7259
    • Yoshida, N.1    Ino, K.2    Ishida, Y.3
  • 44
    • 70349746798 scopus 로고    scopus 로고
    • Role of the immunosuppressive enzyme indoleamine 2, 3-dioxygenase in the progression of ovarian carcinoma
    • Inaba T, Ino K, Kajiyama H, et al. Role of the immunosuppressive enzyme indoleamine 2, 3-dioxygenase in the progression of ovarian carcinoma. Gynecol Oncol 2009;115:185-192.
    • (2009) Gynecol Oncol , vol.115 , pp. 185-192
    • Inaba, T.1    Ino, K.2    Kajiyama, H.3
  • 45
    • 33846689594 scopus 로고    scopus 로고
    • Inhibition of indoleamine 2, 3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses
    • Hou DY, Muller AJ, Sharma MD, et al. Inhibition of indoleamine 2, 3-dioxygenase in dendritic cells by stereoisomers of 1-methyl-tryptophan correlates with antitumor responses. Cancer Res 2007;67:792-801.
    • (2007) Cancer Res , vol.67 , pp. 792-801
    • Hou, D.Y.1    Muller, A.J.2    Sharma, M.D.3
  • 46
    • 33846850363 scopus 로고    scopus 로고
    • (?)-Epigallocatechin gallate suppresses indoleamine 2, 3-dioxygenase expression in murine dendritic cells: Evidences for the COX-2 and STAT1 as potential targets
    • Jeong YI, Jung ID, Lee JS, et al. (?)-Epigallocatechin gallate suppresses indoleamine 2, 3-dioxygenase expression in murine dendritic cells: evidences for the COX-2 and STAT1 as potential targets. Biochem Biophys Res Commun 2007;354:1004-1009.
    • (2007) Biochem Biophys Res Commun , vol.354 , pp. 1004-1009
    • Jeong, Y.I.1    Jung, I.D.2    Lee, J.S.3
  • 47
    • 74849090444 scopus 로고    scopus 로고
    • Indoleamine 2, 3-dioxygenase, an immunomodulatory protein, is suppressed by (?)-epigallocatechin-3-gallate via blocking of gamma-interferon-induced JAK-PKC-delta-STAT1 signaling in human oral cancer cells
    • Cheng CW, Shieh PC, Lin YC, et al. Indoleamine 2, 3-dioxygenase, an immunomodulatory protein, is suppressed by (?)-epigallocatechin-3-gallate via blocking of gamma-interferon-induced JAK-PKC-delta-STAT1 signaling in human oral cancer cells. J Agric Food Chem 2010;58:887-894.
    • (2010) J Agric Food Chem , vol.58 , pp. 887-894
    • Cheng, C.W.1    Shieh, P.C.2    Lin, Y.C.3
  • 48
    • 84862808949 scopus 로고    scopus 로고
    • Suppression of azoxymethaneinduced colonic preneoplastic lesions in rats by 1-methyltryptophan, an inhibitor of indoleamine 2, 3-dioxygenase
    • Ogawa K, Hara T, Shimizu M, et al. Suppression of azoxymethaneinduced colonic preneoplastic lesions in rats by 1-methyltryptophan, an inhibitor of indoleamine 2, 3-dioxygenase. Cancer Sci 2012;103: 951-958.
    • (2012) Cancer Sci , vol.103 , pp. 951-958
    • Ogawa, K.1    Hara, T.2    Shimizu, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.