Genomic resistance island AGI1 carrying a complex class 1 integron in a multiply antibiotic-resistant ST25 Acinetobacter baumannii isolate

Journal of Antimicrobial Chemotherapy

Volumn 70, Issue 9, 2015, Pages 2519-2523

  Hamidian, Mohammad ^a   Holt, Kathryn E ^b   Hall, Ruth M ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

A. baumannii; Acinetobacter genomic island 1; Antibiotic resistance

Indexed keywords

ANTIBIOTIC AGENT; CEPHALOSPORIN DERIVATIVE; CIPROFLOXACIN; CONTIG; GENTAMICIN; KANAMYCIN; NALIDIXIC ACID; NEOMYCIN; SPECTINOMYCIN; STREPTOMYCIN; SULFAMETHOXAZOLE; TOBRAMYCIN; TRIMETHOPRIM; ANTIINFECTIVE AGENT; BACTERIAL DNA;

ACINETOBACTER BAUMANNII; ACINETOBACTER GENOMIC ISLAND 1; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM ISOLATE; DNA SEQUENCE; GENE; GENE DOSAGE; GENE MUTATION; GENE SEQUENCE; GENETIC RESISTANCE; GYRA GENE; INTEGRON; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; RESG GENE; SEQUENCE ANALYSIS; BACTERIAL GENOME; CHEMISTRY; DRUG EFFECTS; GENE ORDER; GENETICS; GENOMIC ISLAND; MOLECULAR GENETICS; MULTIDRUG RESISTANCE;

ACINETOBACTER BAUMANNII; ANTI-BACTERIAL AGENTS; DNA, BACTERIAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; GENE ORDER; GENOME, BACTERIAL; GENOMIC ISLANDS; INTEGRONS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS, DNA;

EID: 84954217481     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkv137     Document Type: Article

References (17)

1. Mulvey MR, Boyd DA, Olson AB et al. The genetics of Salmonella genomic island 1. Microbes Infect 2006; 8: 1915-22.
2. Hall RM. SGI-type genomic islands and antibiotic resistance in Salmonella enterica. Future Microbiol 2010; 5: 125-38.
3. Levings RS, Lightfoot D, Partridge SR et al. The genomic island SGI1, containing the multiple antibiotic resistance region of Salmonella enterica serovar Typhimurium DT104 or variants of it, is widely distributed in other S. enterica serovars. J Bacteriol 2005; 187: 4401-9.
4. Hamidian M, Holt KE, Hall RM. The complete sequence of Salmonella genomic island SGI2. J Antimicrob Chemother 2015; 70: 617-9.
5. Levings RS, Djordjevic SP, Hall RM. SGI2, a relative of Salmonella genomic island SGI1 with an independent origin. Antimicrob Agents Chemother 2008; 52: 2529-37.
6. Siebor E, Neuwirth C. Proteus genomic island 1 (PGI1), a new resistance genomic island from two Proteus mirabilis French clinical isolates. J Antimicrob Chemother 2014; 69: 3216-20.
7. Zarrilli R, Pournaras S, Giannouli M et al. Global evolution of multidrug-resistant Acinetobacter baumannii clonal lineages. Int J Antimicrob Agents 2013; 41: 11-9.
8. Hamidian M, Nigro SJ, Hall RM. Variants of the gentamicin and tobramycin resistance plasmid pRAY are widely distributed in Acinetobacter. J Antimicrob Chemother 2012; 67: 2833-6.
9. Hamidian M, Holt KE, Pickard D et al. A GC1Acinetobacter baumannii isolate carrying AbaR3 and the aminoglycoside resistance transposon TnaphA6 in a conjugative plasmid. J Antimicrob Chemother 2014; 69: 955-8.
10. Hamidian M, Hall RM. Tn6168, a transposon carrying an ISAba1-activated ampC gene and conferring cephalosporin resistance in Acinetobacter baumannii. J Antimicrob Chemother 2014; 69: 77-80.
11. Hamidian M, Hancock DP, Hall RM. Horizontal transfer of an ISAba125-activated ampC gene between Acinetobacter baumannii strains leading to cephalosporin resistance. J Antimicrob Chemother 2013; 68: 244-5.
12. Poirel L, Bonnin RA, Nordmann P. Genetic basis of antibiotic resistance in pathogenic Acinetobacter species. IUBMB Life 2011; 63: 1061-7.
13. PER-1 flanked by miniature inverted-repeat transposable elements in Acinetobacter johnsonii. PLoS One 2014; 9: e90046.
14. Wang F, Wu K, Sun J et al. Novel ISCR1-linked resistance genes found in multidrug-resistant Gram-negative bacteria in southern China. Int J Antimicrob Agents 2012; 40: 404-8.
15. PER-1 gene in Gram-negative bacteria. Antimicrob Agents Chemother 2005; 49: 1708-13.
16. Beaber JW, Hochhut B, Waldor MK. Genomic and functional analyses of SXT, an integrating antibiotic resistance gene transfer element derived from Vibrio cholerae. J Bacteriol 2002; 184: 4259-69.
17. Kamali-Moghaddam M, Sundström L. Transposon targeting determined by resolvase. FEMS Microbiology Letters 2000; 186: 55-9.