Early hemorheological changes in a porcine model of intravenously given E. coli induced fulminant sepsis

Clinical Hemorheology and Microcirculation

Volumn 61, Issue 3, 2016, Pages 479-496

  Nemeth, Norbert ^a   Berhes, Mariann ^a   Kiss, Ferenc ^a   Hajdu, Endre ^a   Deak, Adam ^a   Molnar, Abel ^a   Szabo, Judit ^b   Fulesdi, Bela ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Animal model; E. coli; Red blood cell aggregation; Red blood cell deformability; Sepsis

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL BLOOD; ARTICLE; BLOOD ANALYSIS; BLOOD RHEOLOGY; ERYTHROCYTE AGGREGATION; ERYTHROCYTE DEFORMABILITY; ERYTHROCYTE SEDIMENTATION RATE; ESCHERICHIA COLI; FEMALE; NONHUMAN; PIG; PLASMA VISCOSITY; SEPSIS; VENOUS BLOOD; ANIMAL; BLOOD; CATHETERIZATION; FLOW KINETICS; INFLAMMATION; MEAN CORPUSCULAR VOLUME; MICROCIRCULATION;

ANIMALS; CATHETERIZATION; ERYTHROCYTE AGGREGATION; ERYTHROCYTE DEFORMABILITY; ERYTHROCYTE INDICES; ESCHERICHIA COLI; INFLAMMATION; MICROCIRCULATION; RHEOLOGY; SEPSIS; SWINE;

EID: 84954174433     PISSN: 13860291     EISSN: 18758622     Source Type: Journal    
DOI: 10.3233/CH-141914     Document Type: Article

References (48)

1. E. Alt, B.R. Amann-Vesti, C. Madl, G. Funk and R. Koppensteiner, Platelet aggregation and blood rheology in severe sepsis/septic shock: Relation to the Sepsis-related Organ Failure Assessment (SOFA) score, Clin Hemorheol Microcirc 30 (2004), 107-115.
2. M.E. Astiz, G.E. DeGent, R.Y. Lin and E.C. Rackow, Microvascular function and rheologic changes in hyperdynamic sepsis, Crit Care Med 23 (1995), 265-271.
3. A. Barratt-Due, A. Sokolov, A. Gustavsen, B.C. Hellerud, K. Egge, S.E. Pischke, J.K. Lindstad, A. Pharo, A. Castellheim, E.B. Thorgersen and T.E. Mollnes, Polyvalent immunoglobulin significantly attenuated the formation of IL-1beta in Escherichia coli-induced sepsis in pigs, Immunobiology 218 (2013), 683-689.
4. O.K. Baskurt, Mechanisms of blood rheology alterations, in: Handbook of Hemorheology and Hemodynamics, O.K. Baskurt, M.R. Hardeman, M.W. Rampling and H.J. Meiselman, eds., IOS Press, Amsterdam, The Netherlands, 2007, pp. 170-190.
5. O.K. Baskurt and F. Mat, Importance of measurement temperature in detecting the alterations of red blood cell aggregation and deformability studied by ektacytometry: A study on experimental sepsis in rats, Clin Hemorheol Microcirc 23 (2000), 43-49.
6. O.K. Baskurt and H.J. Meiselman, Data reduction methods for ektacytometry in clinical hemorheology, Clin Hemorheol Microcirc 54 (2013), 99-107.
7. O.K. Baskurt, B. Neu and H.J. Meiselman, Red Blood Cell Aggregation, CRC Press, Boca Raton, USA, 2012, pp. 223-267.
8. O.K. Baskurt, A. Temiz and H.J. Meiselman, Red blood cell aggregation in experimental sepsis, J Lab Clin Med 130 (1997), 183-190.
9. L. Bogar and M. Tekeres, Leukocyte flotation during gravity sedimentation of the whole blood, Clin Hemorheol Microcirc 22 (2000), 29-33.
10. M. Bor-Kucukatay, R.B:Wenby, H.J. Meiselman and O.K. Baskurt, Effects of nitric oxide on red blood cell deformability, Am J Physiol Heart Circ Physiol 284 (2003), H1577-H1584.
11. K.A. Brown, S.D. Brain, J.D. Pearson, J.D. Edgeworth, S.M. Lewis and D.F. Treacher, Neutrophils in development of multiple organ failure in sepsis, The Lancet 368 (2006), 157-169.
12. A. Castellheim, E.B. Thorgersen, B.C. Hellerud, A. Pharo, H.T. Johansen, F. Brosstad, P. Gaustad, H. Brun, E. Fosse, T.I. Tonnessen, E.W. Nielsen and T.E. Mollnes, New biomarkers in an acute model of live Escherichia coli-induced sepsis in pigs, Scand J Immunol 68 (2008), 75-84.
13. V.J. Castro, M.E. Astiz and E.C. Rackow, Effect of crystalloid and colloid solutions on blood rheology in sepsis, Shock 8 (1997), 104-107.
14. J. Chvojka, R. Sykora, A. Krouzecky, J. Radej, V. Varnerova, T. Karvunidis, O. Hes, I. Novak, P. Radermacher and M. Matejovic, Renal haemodynamic, microcirculatory, metabolic and histopathological responses to peritonitis-induced septic shock in pigs, Crit Care 12 (2008), R164.
15. M.R. Clark, N. Mohandas and S.B. Shohet, Osmotic gradient ektacytometry: Comprehensive characterization of red cell volume and surface maintenance, Blood 61 (1983), 899-910.
16. S. Chien, S. Usami, J. Dellenback and V. Magazinovic, Blood rheology after hemorrhage and endotoxin, Adv Exp Med Biol 33 (1972), 75-93.
17. C.T. Esmon, Why do animal models (sometimes) fail to mimic human sepsis Crit, Care Med 32 (2004), S219-S222.
18. M.P. Fink, Animal models of sepsis, Virulence 5 (2014), 143-153.
19. M.R. Hardeman, P.T. Goedhart and S. Shin, Methods in hemorheology, in: Handbook of Hemorheology and Hemodynamics, O.K. Baskurt, M.R. Hardeman, M.W. Rampling and H.J. Meiselman, eds., IOS Press, Amsterdam, The Netherlands, 2007, pp. 242-266.
20. J.E. Jagger, C.G. Ellis, W.J. Sibbald and O. Eichelbrönner, Measurement temperature plays a pivotal role in the distribution of erythrocyte deformability after LPS, Biorheology 38 (2001), 439-448.
21. T. Kato, Relation between blood viscosity and hematocrit in rabbits subjected to repeated treatment with endotoxin, Resuscitation 21 (1991), 61-66.
22. L.A. Kirschenbaum, M. Aziz, M.E. Astiz, D.C. Saha and E.C. Rackow, Influence of rheologic changes and plateletneutrophil interactions on cell filtration in sepsis, Am J Respir Crit Care Med 161 (2000), 1602-1607.
23. M.M. Levy, M.P. Fink, J.C. Marshall, E. Abraham, D. Angus, D. Cook, J. Cohen, S.M. Opal, J.L. Vincent and G. Ramsay, 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference, Crit Care Med 31 (2003), 1250-1256.
24. D.J. Lundy and S. Trzeciak, Microcirculatory dysfunction in sepsis, Crit Care Clin 25 (2009), 721-731.
25. C. Madl, R. Koppensteiner, B. Wendelin, K. Lenz, L. Kramer, G. Grimm, A. Kranz, B. Schneeweiss and H. Ehringer, Effect of immunoglobulin administration on blood rheology in patients with septic shock, Circ Shock 40 (1993), 264-267.
26. A. Matrai, R.B. Whittington and E. Ernst, A simple method of estimating whole blood viscosity at standardized hematocrit, Clin Hemorheol 7 (1987), 261-265.
27. J. Morel, J.Y. Li, P. Eyenga, A. Meiller, M.P. Gustin, G. Bricca, S. Molliex and J.P. Viale, Early adverse changes in liver microvascular circulation during experimental septic shock are not linked to an absolute nitric oxide deficit, Microvasc Res 90 (2013), 187-191.
28. A.G. Moutzouri, A.T. Skoutelis, C.A. Gogos, Y.F. Missirlis and G.M. Athanassiou, Red blood cell deformability in patients with sepsis: A marker for prognosis and monitoring of severity, Clin Hemorheol Microcirc 36 (2007), 291-299.
29. G.B. Nash, T. Watts, C. Thornton and M. Barigou, Red cell aggregation as a factor influencing margination and adhesion of leukocytes and platelets, Clin Hemorheol Microcirc 39 (2008), 303-310.
30. O.O. Nduka and J.E. Parrillo, The pathophysiology of septic shock, Crit Care Nurs Clin North Am 23 (2011), 41-66.
31. N. Nemeth, F. Kiss and K. Miszti-Blasius, Interpretation of osmotic gradient ektacytometry (osmoscan) data: A comparative study for methodological standards, Scand. J Clin Lab Invest (2014)-accepted for publication, doi:10.3109/00365513.2014.993695
32. M. Nishino, H. Tanaka, H. Ogura, Y. Inoue, T. Koh, K. Fujita and H. Sugimoto, Serial changes in leukocyte deformability and whole blood rheology in patients with sepsis or trauma, J Trauma 59 (2005), 1425-1431.
33. M. Piagnerelli, K.Z. Boudjeltia, A. Rapotec, T. Richard, D. Brohee, S. Babar, V. Bouckaert, A.C. Simon, J.P. Toko, T. Walravens, J.L. Vincent and M. Vanhaeverbeek, Neuraminidase alters red blood cells in sepsis, Crit Care Med 37 (2009), 1244-1250.
34. M. Piagnerelli, K.Z. Boudjeltia, M. Vanhaeverbeek and J.L. Vincent, Red blood cell rheology in sepsis, Intensive Care Med 29 (2003), 1052-1061.
35. M. Piagnerelli, F. Cotton, M. Van Nuffelen, J.L. Vincent and B. Gulbis, Modifications in erythrocyte membrane protein content are not responsible for the alterations in rheology seen in sepsis, Shock 37 (2012), 17-21.
36. M. Piagnerelli, K. Zouaoui Boudjeltia, P. Piro, D. Brohee, M.Vanhaeverbeek and J.L.Vincent, Effects of sample temperature on red blood cell shape in septic patients, Clin Hemorheol Microcirc 30 (2004), 463-466.
37. L.F. Poli-de-Figueiredo, A.G. Garrido, N. Nakagawa and P. Sannomiya, Experimental models of sepsis and their clinical relevance Shock 30 Suppl 1 (2008), 53-59.
38. J.M.N. Pöschl, C. Leray, P. Ruef, J.P. Cazenave and O. Linderkamp, Endotoxin binding to erythrocyte membrane and erythryocyte deformability in human sepsis and in vitro, Crit Care Med 31 (2003), 924-928.
39. G. Reggiori, G. Occhipinti, A. De Gasperi, J.L. Vincent and M. Piagnerelli, Early alterations of red blood cell rheology in critically ill patients, Crit Care Med 37 (2009), 3041-3046.
40. D.G. Remick, Pathophysiology of sepsis, Am J Pathol 170 (2007), 1435-1444.
41. T. Sordia, J. Tatarishvili and G. Mchedlishvili, Hemorheological disorders in the microcirculation during septic shock in rats, Clin Hemorheol Microcirc 35 (2006), 223-226.
42. P.E. Spronk, D.F. Zandstra and C. Ince, Bench-to-bedside review: Sepsis is a disease of the microcirculation, Crit Care 8 (2004), 462-468.
43. M.E. Starr and H. Saito, Sepsis in old age: Review of human and animal studies, Aging Dis 5 (2014), 126-136.
44. E.B. Thorgersen, B.C. Hellerud, E.W. Nielsen, A. Barratt-Due, H. Fure, J.K. Lindstad, A. Pharo, E. Fosse, T.I. Tonnessen, H.T. Johansen, A. Castellheim and T.E. Mollnes, CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli sepsis in pigs, FASEB J 24 (2010), 712-722.
45. A. Tyagi, A.K. Sethi, G. Girotra and M. Mohta, The microcirculation in sepsis, Indian J Anaesth 53 (2009), 281-293.
46. T.Wester, E. Haggblad, Z.A. Awan, A. Barratt-Due, M. Kvernebo, P.S. Halvorsen, T.E. Mollnes and K. Kvernebo, Assessments of skin and tongue microcirculation reveals major changes in porcine sepsis, Clin Physiol Funct Imaging 31 (2011), 151-158.
47. J.L. Wynn and H.R. Wong, Pathophysiology and treatment of septic shock in neonates, Clin Perinatol 37 (2010), 439-479.
48. P.C. Yodice, M.A. Astiz, B.M. Kurian, R.Y. Lim and E.C. Rackow, Neutrophil rheological changes in septic shock, Am J Respir Crit Care Med 155 (1997), 38-42.