Ultrasensitive Detection of Multiplexed Somatic Mutations Using MALDI-TOF Mass Spectrometry

Journal of Molecular Diagnostics

Volumn 18, Issue 1, 2016, Pages 23-31

  Mosko, Michael J ^a   Nakorchevsky, Aleksey A ^a   Flores, Eunice ^a   Metzler, Heath ^a   Ehrich, Mathias ^b   Van Den Boom, Dirk J ^b   Sherwood, James L ^c   Nygren, Anders O H ^a  

^a AGENA BIOSCIENCE   (United States)

^b SEQUENOM INC   (United States)

^c ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; DNA;

ALLELE; ARTICLE; CANCER PATIENT; CLINICAL LABORATORY; COMPARATIVE STUDY; GENE AMPLIFICATION; GENE FREQUENCY; GENETIC VARIABILITY; HIGH THROUGHPUT SEQUENCING; HT 29 CELL LINE; HUMAN; HUMAN CELL; INVERSE POLYMERASE CHAIN REACTION; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MISSENSE MUTATION; MULTIPLEX POLYMERASE CHAIN REACTION; MUTATION RATE; POINT MUTATION; POLYMERASE CHAIN REACTION SYSTEM; QUALITY CONTROL; SOMATIC MUTATION; BLOOD; GENETICS; LIMIT OF DETECTION; MATRIX-ASSISTED LASER DESORPTION-IONIZATION MASS SPECTROMETRY; MELANOMA; MUTATION; PROCEDURES; TUMOR CELL LINE;

ALLELES; CELL LINE, TUMOR; DNA; GENE FREQUENCY; HUMANS; LIMIT OF DETECTION; MELANOMA; MULTIPLEX POLYMERASE CHAIN REACTION; MUTATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84954046405     PISSN: 15251578     EISSN: 19437811     Source Type: Journal    
DOI: 10.1016/j.jmoldx.2015.08.001     Document Type: Article

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