Glutathione levels in plasma, saliva and gingival crevicular fluid after periodontal therapy in obese and normal weight individuals

Journal of Periodontal Research

Volumn 51, Issue 6, 2016, Pages 726-734

  Ongoz Dede F ^a   Bozkurt Dogan S ^a   Balli, U ^a   Avci, B ^b   Durmuslar M C ^a   Baratzade, T ^b  

^a ZONGULDAK KARAELMAS UNIVERSITY   (Turkey)

^b ONDOKUZ MAYIS UNIVERSITY   (Turkey)

Author keywords

antioxidants; chronic periodontitis; glutathione; obesity

Indexed keywords

GLUTATHIONE; GLUTATHIONE DISULFIDE;

ADULT; BLOOD; CASE CONTROL STUDY; CHEMISTRY; COMPLICATION; FEMALE; GINGIVITIS; HUMAN; MALE; METABOLISM; MIDDLE AGED; OBESITY; PERIODONTITIS; SALIVA;

ADULT; CASE-CONTROL STUDIES; FEMALE; GINGIVAL CREVICULAR FLUID; GLUTATHIONE; GLUTATHIONE DISULFIDE; HUMANS; MALE; MIDDLE AGED; OBESITY; PERIODONTITIS; SALIVA;

EID: 84953792345     PISSN: 00223484     EISSN: 16000765     Source Type: Journal    
DOI: 10.1111/jre.12349     Document Type: Article

References (43)

1. Bullon P, Newman HN, Battino M. Obesity, diabetes mellitus, atherosclerosis and chronic periodontitis: a shared pathology via oxidative stress and mitochondrial dysfunction? Periodontol 2000 2014;64:139–153.
2. Pischon N, Heng N, Bernimoulin JP, Kleber BM, Willich SN, Pischon T. Obesity, inflammation, and periodontal disease. J Dent Res 2007;86:400–409.
3. Jagannathachary S, Kamaraj D. Obesity and periodontal disease. J Indian Soc Periodontol 2010;14:96–100.
4. Ye ZW, Zhang J, Townsend DM, Tew KD. Oxidative stress, redox regulation and diseases of cellular differentiation. Biochim Biophys Acta 2015;1850:1607–1621.
5. Albuali WH. Evaluation of oxidant-antioxidant status in overweight and morbidly obese Saudi children. World J Clin Pediatr 2014;8:6–13.
6. Vincent HK, Innes KE, Vincent KR. Oxidative stress and potential interventions to reduce oxidative stress in overweight and obesity. Diabetes Obes Metab 2007;9:813–839.
7. Chapple IL, Matthews JB. The role of reactive oxygen and antioxidant species in periodontal tissue destruction. Periodontol 2000 2007;43:160–232.
8. Ridgeway EE. Periodontal disease: diagnosis and management. J Am Acad Nurse Pract 2000;12:79–84.
9. Di Renzo L, Galvano F, Orlandi C et al. Oxidative stress in normal-weight obese syndrome. Obesity 2010;18:2125–2130.
10. Kaur S, Zilmer K, Kairane C, Kals M, Zilmer M. Clear differences in adiponectin level and glutathione redox status revealed in obese and normal-weight patients with psoriasis. Br J Dermatol 2008;159:1364–1367.
11. Chapple ILC, Brock G, Eftimiadi C, Matthews JB. Glutathione in gingival crevicular fluid and its relation to local antioxidant capacity in periodontal health and disease. Mol Pathol 2002;55:367–373.
12. Panjamurthy K, Manoharan S, Ramachandran CR. Lipid peroxidation and antioxidant status in patients with periodontitis. Cell Mol Biol Lett 2005;10:255–264.
13. Grant MM, Brock GR, Matthews JB, Chapple ILC. Crevicular fluid glutathione levels in periodontitis and the effect of non-surgical therapy. J Clin Periodontol 2010;37:17–23.
14. Tsai CC, Chen HS, Chen SL et al. Lipid peroxidation: a possible role in the induction and progression of chronic periodontitis. J Periodontal Res 2005;40:378–384.
15. Biju T, Shabeer MM, Amitha R, Rajendra BP, Suchetha K. Comparitive evaluation of serum superoxide dismutase and glutathione levels in periodontally diseased patients: an interventional study. Indian J Dent Res 2014;25:613–616.
16. Barnes VM, Kennedy AD, Panagakos F et al. Global metabolomic analysis of human saliva and plasma from healthy and diabetic subjects, with and without periodontal disease. PLoS One 2014;9:e105181.
17. Tomofuji T, Yamamoto T, Tamaki N et al. Effects of obesity on gingival oxidative stress in a rat model. J Periodontol 2009;80:1324–1329.
18. Azuma T, Tomofuji T, Endo Y et al. Effects of exercise training on gingival oxidative stress in obese rats. Arch Oral Biol 2011;56:768–774.
19. World Health Organization. Obesity: Preventing and Managing the Global Epidemic. Report of WHO Consultation on Obesity. Geneva: WHO, 1997: 9–12.
20. World Health Organization. Waist Circumference and Waist-Hip Ratio: Report of a WHO Expert Consultation. Geneva: WHO, 2008: 1–47.
21. Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999;4:1–6.
22. Löe H, Silness J. Periodontal disease in pregnancy. I. Prevalence and severity. Acta Odontol Scand 1963;21:531–551.
23. Ainamo J, Bay I. Problems and proposals for recording gingivitis and plaque. Int Dent J 1975;25:229–235.
24. Silness J, Löe H. Periodontal disease in pregnancy. II. Correletion between oral hygiene and periodontal condition. Acta Odontol Scand 1964;22:121–135.
25. Navazesh M. Methods for collecting saliva. Ann N Y Acad Sci 1993;694:72–77.
26. Rudin HJ, Overdiek HF, Rateitschak KH. Correlation between sulcus fluid rate and clinical and histological inflammation of the marginal gingiva. Helv Odontol Acta 1970;14:21–26.
27. Ritchie CS, Kinane DF. Nutrition, inflammation and periodontal disease. Nutrition 2003;19:475–476.
28. Boesing F, Patino JSR, da Silva VRG, Moreira EAM. The interface between obesity and periodontitis with emphasis on oxidative stress and inflammatory response. Obesity 2009;10:290–297.
29. Chaffee BW, Weston SJ. Association between chronic periodontal disease and obesity: a systematic review and meta-analysis. J Periodontol 2010;81:1708–1724.
30. Shimazaki Y, Egami Y, Matsubara T et al. Relationship between obesity and physical fitness and periodontitis. J Periodontol 2010;81:1124–1131.
31. Zuza EP, Barroso EM, Carrareto ALV et al. The role of obesity as a modifying factor in patients undergoing non-surgical periodontal therapy. J Periodontol 2011;82:676–682.
32. Sculley DV, Langley-Evans SC. Salivary antioxidants and periodontal disease status. Proc Nutr Soc 2002;61:137–143.
33. Moore S, Calder KA, Miller NJ, Rice-Evans CA. Antioxidant activity of saliva and periodontal disease. Free Radic Res 1994;21:417–425.
34. Lamster IB, Oshrain RL, Fiorello LA, Celenti RS, Gordon JM. A comparison of 4 methods of data presentation for lysosomal enzyme activity in gingival crevicular fluid. J Clin Periodontol 1988;15:347–352.
35. Munoz-Torres FJ, Jimenez MC, Rivas-Tumanyan S, Joshipura KJ. Associations between measures of central adiposity and periodontitis among older adults. Community Dent Oral 2014;42:170–177.
36. Suvan J, Petrie A, Moles DR et al. Body Mass Index as a predictive factor of periodontal therapy outcomes. J Dent Res 2014;93:49–54.
37. Dahiya P, Kamal R, Gupta R. Obesity, periodontal and general health: relationship and management. Indian J Endocr Metab 2012;16:88–93.
38. Dias IH, Chapple IL, Milward M et al. Sulforaphane restores cellular glutathione levels and reduces chronic periodontitis neutrophil hyperactivity in vitro. PLoS One 2013;24:e66407.
39. Savita AM, Sarun E, Arora S, Krishnan S. Evaluation of glutathione level in gingival crevicular fluid in periodontal health, in chronic periodontitis and after nonsurgical periodontal therapy: a clinicobiochemical study. Contemp Clin Dent 2015;6:206–210.
40. Chu L, Dong Z, Xu X, Cochran DL, Ebersole JL. Role of glutathione metabolism of Treponema denticola in bacterial growth and virulence expression. Infect Immun 2002;70:1113–1120.
41. Million M, Maraninchi M, Henry M et al. Obesity-associated gut microbiota is enriched in Lactobacillus reuteri and depleted in Bifidobacterium animalis and Methanobrevibacter smithii. Int J Obes (Lond) 2012;36:817–825.
42. Ao M, Miyauchi M, Inubushi T et al. Infection with Porphyromonas gingivalis exacerbates endothelial injury in obese mice. PLoS One 2014;21:e110519.
43. Saito T, Shimazaki Y. Metabolic disorders related to obesity and periodontal disease. Periodontol 2000 2007;43:254–266.