RhoA orchestrates glycolysis for TH2 cell differentiation and allergic airway inflammation

Journal of Allergy and Clinical Immunology

Volumn 137, Issue 1, 2016, Pages 231-245.e4

  Yang, Jun Qi ^a,b   Kalim, Khalid W ^a   Li, Yuan ^a   Zhang, Shuangmin ^a   Hinge, Ashwini ^a   Filippi, Marie Dominique ^a   Zheng, Yi ^a   Guo, Fukun ^a  

^a CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^b BEIJING HOSPITAL   (China)

Author keywords

allergic airway inflammation; glycolysis; RhoA; T cell metabolism; TH2 differentiation

Indexed keywords

CD11B ANTIGEN; CD2 ANTIGEN; CD28 ANTIGEN; CD4 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; EOTAXIN; GLYCOPROTEIN P 15095; HERMES ANTIGEN; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 4 RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MESSENGER RNA; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; STAT6 PROTEIN; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR NFAT; ALLERGEN; OVALBUMIN;

ALLERGIC AIRWAY INFLAMMATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL INFILTRATION; CELL LINEAGE; CELL METABOLISM; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION; GLYCOLYSIS; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN DEFICIENCY; T LYMPHOCYTE ACTIVATION; TH2 CELL; TRANSGENIC MOUSE; WESTERN BLOTTING; ANIMAL; CYTOLOGY; DEFICIENCY; GENETICS; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; METABOLISM; RESPIRATORY TRACT ALLERGY;

ALLERGENS; ANIMALS; CELL DIFFERENTIATION; GLYCOLYSIS; INFLAMMATION; MICE, KNOCKOUT; MICE, TRANSGENIC; OVALBUMIN; RESPIRATORY HYPERSENSITIVITY; RHOA GTP-BINDING PROTEIN; TH2 CELLS;

EID: 84953638636     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.05.004     Document Type: Article

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