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Volumn 142, Issue 1, 2016, Pages 305-315

Long-term follow-up of the AML97 study for patients aged 60 years and above with acute myeloid leukaemia: a study of the East German Haematology and Oncology Study Group (OSHO)

(22)  Kahl, C a,b   Krahl, R c   Becker, C c   Al Ali, H K c   Sayer, H G d,e   Schulze, A d   Herold, M d   Hanel M f   Scholl, S e   Hochhaus, A e   Uharek, L g   Maschmeyer, G h   Haehling, D i   Junghanss C b   Peter, N j   Kampfe D k   Kettner, E a   Heinicke, T l   Fischer, T l   Kreibich, U m   more..


Author keywords

AML; Elderly; Long term follow up; Therapy

Indexed keywords

AMSACRINE; ANTHRACYCLINE; CYTARABINE; ETOPOSIDE; IDARUBICIN; MITOXANTRONE; PREDNISOLONE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; TIOGUANINE; ANTINEOPLASTIC AGENT;

EID: 84953637893     PISSN: 01715216     EISSN: 14321335     Source Type: Journal    
DOI: 10.1007/s00432-015-2045-8     Document Type: Article
Times cited : (20)

References (39)
  • 1
    • 84855416811 scopus 로고    scopus 로고
    • Azacitidine in patients with acute myeloid leukemia medically unfit for or resistant to chemotherapy: a multicenter phase I/II study
    • PID: 21767242, COI: 1:CAS:528:DC%2BC38Xjs1Cntg%3D%3D
    • Al-Ali HK, Jaekel N, Junghanss C, Maschmeyer G, Krahl R, Cross M, Hoppe G, Niederwieser D (2012) Azacitidine in patients with acute myeloid leukemia medically unfit for or resistant to chemotherapy: a multicenter phase I/II study. Leuk Lymphoma 53:110–117
    • (2012) Leuk Lymphoma , vol.53 , pp. 110-117
    • Al-Ali, H.K.1    Jaekel, N.2    Junghanss, C.3    Maschmeyer, G.4    Krahl, R.5    Cross, M.6    Hoppe, G.7    Niederwieser, D.8
  • 2
    • 84893697515 scopus 로고    scopus 로고
    • The role of hypomethylating agents in the treatment of elderly patients with AML
    • PID: 24484723
    • Al-Ali HK, Jaekel N, Niederwieser D (2014) The role of hypomethylating agents in the treatment of elderly patients with AML. J Geriatr Oncol 5:89–105
    • (2014) J Geriatr Oncol , vol.5 , pp. 89-105
    • Al-Ali, H.K.1    Jaekel, N.2    Niederwieser, D.3
  • 3
    • 17544388046 scopus 로고    scopus 로고
    • Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype
    • PID: 9751631, COI: 1:CAS:528:DyaK1cXmtlCksLo%3D
    • Bloomfield CD, Lawrence D, Byrd JC, Carroll A, Pettenati MJ, Tantravahi R, Patil SR, Davey FR, Berg DT, Schiffer CA et al (1998) Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype. Cancer Res 58:4173–4179
    • (1998) Cancer Res , vol.58 , pp. 4173-4179
    • Bloomfield, C.D.1    Lawrence, D.2    Byrd, J.C.3    Carroll, A.4    Pettenati, M.J.5    Tantravahi, R.6    Patil, S.R.7    Davey, F.R.8    Berg, D.T.9    Schiffer, C.A.10
  • 4
    • 0345104178 scopus 로고    scopus 로고
    • Double induction strategy for acute myeloid leukemia: the effect of high-dose cytarabine with mitoxantrone instead of standard-dose cytarabine with daunorubicin and 6-thioguanine: a randomized trial by the German AML Cooperative Group
    • PID: 10361108, COI: 1:CAS:528:DyaK1MXjvVGrtro%3D
    • Buchner T, Hiddemann W, Wormann B, Loffler H, Gassmann W, Haferlach T, Fonatsch C, Haase D, Schoch C, Hossfeld D et al (1999) Double induction strategy for acute myeloid leukemia: the effect of high-dose cytarabine with mitoxantrone instead of standard-dose cytarabine with daunorubicin and 6-thioguanine: a randomized trial by the German AML Cooperative Group. Blood 93:4116–4124
    • (1999) Blood , vol.93 , pp. 4116-4124
    • Buchner, T.1    Hiddemann, W.2    Wormann, B.3    Loffler, H.4    Gassmann, W.5    Haferlach, T.6    Fonatsch, C.7    Haase, D.8    Schoch, C.9    Hossfeld, D.10
  • 7
    • 33745003472 scopus 로고    scopus 로고
    • Double induction containing either two courses or one course of high-dose cytarabine plus mitoxantrone and postremission therapy by either autologous stem-cell transplantation or by prolonged maintenance for acute myeloid leukemia
    • PID: 16735702
    • Buchner T, Berdel WE, Schoch C, Haferlach T, Serve HL, Kienast J, Schnittger S, Kern W, Tchinda J, Reichle A et al (2006) Double induction containing either two courses or one course of high-dose cytarabine plus mitoxantrone and postremission therapy by either autologous stem-cell transplantation or by prolonged maintenance for acute myeloid leukemia. J Clin Oncol 24:2480–2489
    • (2006) J Clin Oncol , vol.24 , pp. 2480-2489
    • Buchner, T.1    Berdel, W.E.2    Schoch, C.3    Haferlach, T.4    Serve, H.L.5    Kienast, J.6    Schnittger, S.7    Kern, W.8    Tchinda, J.9    Reichle, A.10
  • 8
    • 0037114753 scopus 로고    scopus 로고
    • Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461)
    • PID: 12393746, COI: 1:CAS:528:DC%2BD38XpsFCqs7o%3D
    • Byrd JC, Mrozek K, Dodge RK, Carroll AJ, Edwards CG, Arthur DC, Pettenati MJ, Patil SR, Rao KW, Watson MS et al (2002) Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461). Blood 100:4325–4336
    • (2002) Blood , vol.100 , pp. 4325-4336
    • Byrd, J.C.1    Mrozek, K.2    Dodge, R.K.3    Carroll, A.J.4    Edwards, C.G.5    Arthur, D.C.6    Pettenati, M.J.7    Patil, S.R.8    Rao, K.W.9    Watson, M.S.10
  • 9
    • 0026721131 scopus 로고
    • The classification of acute leukaemia
    • PID: 1578905
    • Catovsky D, Matutes E (1992) The classification of acute leukaemia. Leukemia 6(Suppl 2):1–6
    • (1992) Leukemia , vol.6 , pp. 1-6
    • Catovsky, D.1    Matutes, E.2
  • 11
    • 84889661479 scopus 로고    scopus 로고
    • Reduced intensity allogeneic hematopoietic transplantation is an established standard of care for treatment of older patients with acute myeloid leukemia
    • PID: 24309534
    • Champlin R (2013) Reduced intensity allogeneic hematopoietic transplantation is an established standard of care for treatment of older patients with acute myeloid leukemia. Best Pract Res Clin Haematol 26:297–300
    • (2013) Best Pract Res Clin Haematol , vol.26 , pp. 297-300
    • Champlin, R.1
  • 14
    • 0035469856 scopus 로고    scopus 로고
    • Attempts to improve treatment outcomes in acute myeloid leukemia (AML) in older patients: the results of the United Kingdom Medical Research Council AML11 trial
    • PID: 11520775, COI: 1:CAS:528:DC%2BD3MXmvFGjtr8%3D
    • Goldstone AH, Burnett AK, Wheatley K, Smith AG, Hutchinson RM, Clark RE (2001) Attempts to improve treatment outcomes in acute myeloid leukemia (AML) in older patients: the results of the United Kingdom Medical Research Council AML11 trial. Blood 98:1302–1311
    • (2001) Blood , vol.98 , pp. 1302-1311
    • Goldstone, A.H.1    Burnett, A.K.2    Wheatley, K.3    Smith, A.G.4    Hutchinson, R.M.5    Clark, R.E.6
  • 15
    • 0027076295 scopus 로고
    • Southwest Oncology Group standard response criteria, endpoint definitions and toxicity criteria
    • PID: 1487397, COI: 1:STN:280:DyaK3s7jvV2jsw%3D%3D
    • Green S, Weiss GR (1992) Southwest Oncology Group standard response criteria, endpoint definitions and toxicity criteria. Invest New Drugs 10:239–253
    • (1992) Invest New Drugs , vol.10 , pp. 239-253
    • Green, S.1    Weiss, G.R.2
  • 16
    • 0032188805 scopus 로고    scopus 로고
    • The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children’s Leukaemia Working Parties
    • PID: 9746770, COI: 1:CAS:528:DyaK1cXmsVKnsrw%3D
    • Grimwade D, Walker H, Oliver F, Wheatley K, Harrison C, Harrison G, Rees J, Hann I, Stevens R, Burnett A et al (1998) The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children’s Leukaemia Working Parties. Blood 92:2322–2333
    • (1998) Blood , vol.92 , pp. 2322-2333
    • Grimwade, D.1    Walker, H.2    Oliver, F.3    Wheatley, K.4    Harrison, C.5    Harrison, G.6    Rees, J.7    Hann, I.8    Stevens, R.9    Burnett, A.10
  • 18
    • 0027093461 scopus 로고
    • Differences in the intracellular pharmacokinetics of cytosine arabinoside (AraC) between circulating leukemic blasts and normal mononuclear blood cells
    • PID: 1453772, COI: 1:STN:280:DyaK3s%2Fos1WmtA%3D%3D
    • Hiddemann W, Schleyer E, Unterhalt M, Zuhlsdorf M, Rolf C, Reuter C, Kewer U, Uhrmeister C, Wormann B, Buchner T (1992) Differences in the intracellular pharmacokinetics of cytosine arabinoside (AraC) between circulating leukemic blasts and normal mononuclear blood cells. Leukemia 6:1273–1280
    • (1992) Leukemia , vol.6 , pp. 1273-1280
    • Hiddemann, W.1    Schleyer, E.2    Unterhalt, M.3    Zuhlsdorf, M.4    Rolf, C.5    Reuter, C.6    Kewer, U.7    Uhrmeister, C.8    Wormann, B.9    Buchner, T.10
  • 19
    • 0002459325 scopus 로고    scopus 로고
    • Pathology and genetics of tumors of haematopoietic and lymphoid tissues
    • Jaffe ES, Harris NL, Stein JE, Variakojis D, (eds), IARC Press, Lyon
    • Jaffe ES (2001) Pathology and genetics of tumors of haematopoietic and lymphoid tissues. In: Jaffe ES, Harris NL, Stein JE, Variakojis D (eds) World Health Organization classification of tumors. IARC Press, Lyon
    • (2001) World Health Organization classification of tumors
    • Jaffe, E.S.1
  • 22
    • 84864063679 scopus 로고    scopus 로고
    • Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia
    • PID: 22689805, COI: 1:CAS:528:DC%2BC38Xht1ygsr%2FI
    • Kantarjian HM, Thomas XG, Dmoszynska A, Wierzbowska A, Mazur G, Mayer J, Gau JP, Chou WC, Buckstein R, Cermak J et al (2012) Multicenter, randomized, open-label, phase III trial of decitabine versus patient choice, with physician advice, of either supportive care or low-dose cytarabine for the treatment of older patients with newly diagnosed acute myeloid leukemia. J Clin Oncol 30:2670–2677
    • (2012) J Clin Oncol , vol.30 , pp. 2670-2677
    • Kantarjian, H.M.1    Thomas, X.G.2    Dmoszynska, A.3    Wierzbowska, A.4    Mazur, G.5    Mayer, J.6    Gau, J.P.7    Chou, W.C.8    Buckstein, R.9    Cermak, J.10
  • 23
    • 0002391815 scopus 로고
    • The Clinical Evaluation of Chemotherapeutic Agents in Cancer
    • MacLeod C, (ed), Columbia University Press, New York
    • Karnofsky D, Burchenal J (1949) The Clinical Evaluation of Chemotherapeutic Agents in Cancer. In: MacLeod C (ed) Evaluation of Chemotherapeutic Agents. Columbia University Press, New York
    • (1949) Evaluation of Chemotherapeutic Agents
    • Karnofsky, D.1    Burchenal, J.2
  • 24
    • 17344366634 scopus 로고    scopus 로고
    • Superiority of high-dose over intermediate-dose cytosine arabinoside in the treatment of patients with high-risk acute myeloid leukemia: results of an age-adjusted prospective randomized comparison
    • PID: 9665189, COI: 1:CAS:528:DyaK1cXkvVensLk%3D
    • Kern W, Aul C, Maschmeyer G, Schonrock-Nabulsi R, Ludwig WD, Bartholomaus A, Bettelheim P, Wormann B, Buchner T, Hiddemann W (1998) Superiority of high-dose over intermediate-dose cytosine arabinoside in the treatment of patients with high-risk acute myeloid leukemia: results of an age-adjusted prospective randomized comparison. Leukemia 12:1049–1055
    • (1998) Leukemia , vol.12 , pp. 1049-1055
    • Kern, W.1    Aul, C.2    Maschmeyer, G.3    Schonrock-Nabulsi, R.4    Ludwig, W.D.5    Bartholomaus, A.6    Bettelheim, P.7    Wormann, B.8    Buchner, T.9    Hiddemann, W.10
  • 25
    • 0033975925 scopus 로고    scopus 로고
    • Multivariate analysis of prognostic factors in patients with refractory and relapsed acute myeloid leukemia undergoing sequential high-dose cytosine arabinoside and mitoxantrone (S-HAM) salvage therapy: relevance of cytogenetic abnormalities
    • PID: 10673737, COI: 1:STN:280:DC%2BD3c7jvFGnsw%3D%3D
    • Kern W, Schoch C, Haferlach T, Braess J, Unterhalt M, Wormann B, Buchner T, Hiddemann W (2000) Multivariate analysis of prognostic factors in patients with refractory and relapsed acute myeloid leukemia undergoing sequential high-dose cytosine arabinoside and mitoxantrone (S-HAM) salvage therapy: relevance of cytogenetic abnormalities. Leukemia 14:226–231
    • (2000) Leukemia , vol.14 , pp. 226-231
    • Kern, W.1    Schoch, C.2    Haferlach, T.3    Braess, J.4    Unterhalt, M.5    Wormann, B.6    Buchner, T.7    Hiddemann, W.8
  • 27
    • 0036193018 scopus 로고    scopus 로고
    • Intermediate-dose cytarabine treatment delivered at moderate infusion rates for de novo acute myeloid leukemia-results of a phase I-II study
    • PID: 11999557, COI: 1:CAS:528:DC%2BD38XntVarurY%3D
    • Mantovani L, Hasenclever D, Krahl R, Ponisch W, Herold M, Pasold R, Fiedler F, Dolken G, Kampfe D, Schmoll HJ et al (2002) Intermediate-dose cytarabine treatment delivered at moderate infusion rates for de novo acute myeloid leukemia-results of a phase I-II study. Leuk Lymphoma 43:265–274
    • (2002) Leuk Lymphoma , vol.43 , pp. 265-274
    • Mantovani, L.1    Hasenclever, D.2    Krahl, R.3    Ponisch, W.4    Herold, M.5    Pasold, R.6    Fiedler, F.7    Dolken, G.8    Kampfe, D.9    Schmoll, H.J.10
  • 28
    • 0642373288 scopus 로고    scopus 로고
    • Assessment of differences in patient populations selected for excluded from participation in clinical phase III acute myelogenous leukemia trials
    • PID: 14581417
    • Mengis C, Aebi S, Tobler A, Dahler W, Fey MF (2003) Assessment of differences in patient populations selected for excluded from participation in clinical phase III acute myelogenous leukemia trials. J Clin Oncol 21:3933–3939
    • (2003) J Clin Oncol , vol.21 , pp. 3933-3939
    • Mengis, C.1    Aebi, S.2    Tobler, A.3    Dahler, W.4    Fey, M.F.5
  • 30
    • 77955575938 scopus 로고    scopus 로고
    • Long-term disease-free survival after nonmyeloablative cyclophosphamide/fludarabine conditioning and related/unrelated allotransplantation for acute myeloid leukemia/myelodysplasia
    • PID: 20062092, COI: 1:CAS:528:DC%2BC3cXhtVajsL3K
    • Nelson RP Jr, Yu M, Schwartz JE, Robertson MJ, Hromas R, Fausel CA, Vance GH, Dlouhy SR, Baute JA, Cox EA et al (2010) Long-term disease-free survival after nonmyeloablative cyclophosphamide/fludarabine conditioning and related/unrelated allotransplantation for acute myeloid leukemia/myelodysplasia. Bone Marrow Transplant 45:1300–1308
    • (2010) Bone Marrow Transplant , vol.45 , pp. 1300-1308
    • Nelson, R.P.1    Yu, M.2    Schwartz, J.E.3    Robertson, M.J.4    Hromas, R.5    Fausel, C.A.6    Vance, G.H.7    Dlouhy, S.R.8    Baute, J.A.9    Cox, E.A.10
  • 31
    • 84893788771 scopus 로고    scopus 로고
    • Declining rates of treatment-related mortality in patients with newly diagnosed AML given ‘intense’ induction regimens: a report from SWOG and MD Anderson
    • PID: 23760400, COI: 1:CAS:528:DC%2BC2cXhsl2huro%3D
    • Othus M, Kantarjian H, Petersdorf S, Ravandi F, Godwin J, Cortes J, Pierce S, Erba H, Faderl S, Appelbaum FR et al (2014) Declining rates of treatment-related mortality in patients with newly diagnosed AML given ‘intense’ induction regimens: a report from SWOG and MD Anderson. Leukemia 28:289–292
    • (2014) Leukemia , vol.28 , pp. 289-292
    • Othus, M.1    Kantarjian, H.2    Petersdorf, S.3    Ravandi, F.4    Godwin, J.5    Cortes, J.6    Pierce, S.7    Erba, H.8    Faderl, S.9    Appelbaum, F.R.10
  • 33
    • 0023356575 scopus 로고
    • Saturation of ara-CTP accumulation during high-dose ara-C therapy: pharmacologic rationale for intermediate-dose ara-C
    • PID: 3589690, COI: 1:STN:280:DyaL2s3jsVeqsw%3D%3D
    • Plunkett W, Liliemark JO, Estey E, Keating MJ (1987a) Saturation of ara-CTP accumulation during high-dose ara-C therapy: pharmacologic rationale for intermediate-dose ara-C. Semin Oncol 14:159–166
    • (1987) Semin Oncol , vol.14 , pp. 159-166
    • Plunkett, W.1    Liliemark, J.O.2    Estey, E.3    Keating, M.J.4
  • 34
    • 0023176899 scopus 로고
    • Effect of amsacrine on ara-CTP cellular pharmacology in human leukemia cells during high-dose cytarabine therapy
    • PID: 3567973, COI: 1:STN:280:DyaL2s7oslegsA%3D%3D
    • Plunkett W, Nowak B, Keating MJ (1987b) Effect of amsacrine on ara-CTP cellular pharmacology in human leukemia cells during high-dose cytarabine therapy. Cancer Treat Rep 71:479–483
    • (1987) Cancer Treat Rep , vol.71 , pp. 479-483
    • Plunkett, W.1    Nowak, B.2    Keating, M.J.3
  • 35
    • 0036673816 scopus 로고    scopus 로고
    • Intensified double induction therapy with high dose mitoxantrone, etoposide, m-amsacrine and high dose ara-C for elderly acute myeloid leukemia patients aged 61-65 years
    • PID: 12161356, COI: 1:CAS:528:DC%2BD38Xnt1Whurc%3D
    • Schaich M, Illmer T, Aulitzky W, Bodenstein H, Clemens M, Neubauer A, Repp R, Schakel U, Soucek S, Wandt H et al (2002) Intensified double induction therapy with high dose mitoxantrone, etoposide, m-amsacrine and high dose ara-C for elderly acute myeloid leukemia patients aged 61-65 years. Haematologica 87:808–815
    • (2002) Haematologica , vol.87 , pp. 808-815
    • Schaich, M.1    Illmer, T.2    Aulitzky, W.3    Bodenstein, H.4    Clemens, M.5    Neubauer, A.6    Repp, R.7    Schakel, U.8    Soucek, S.9    Wandt, H.10
  • 36
    • 0029033064 scopus 로고
    • Granulocyte-macrophage colony-stimulating factor after initial chemotherapy for elderly patients with primary acute myelogenous leukemia. Cancer and Leukemia Group B
    • PID: 7760868, COI: 1:STN:280:DyaK2M3otV2ktA%3D%3D
    • Stone RM, Berg DT, George SL, Dodge RK, Paciucci PA, Schulman P, Lee EJ, Moore JO, Powell BL, Schiffer CA (1995) Granulocyte-macrophage colony-stimulating factor after initial chemotherapy for elderly patients with primary acute myelogenous leukemia. Cancer and Leukemia Group B. N Engl J Med 332:1671–1677
    • (1995) N Engl J Med , vol.332 , pp. 1671-1677
    • Stone, R.M.1    Berg, D.T.2    George, S.L.3    Dodge, R.K.4    Paciucci, P.A.5    Schulman, P.6    Lee, E.J.7    Moore, J.O.8    Powell, B.L.9    Schiffer, C.A.10
  • 37
    • 0035437132 scopus 로고    scopus 로고
    • Postremission therapy in older patients with de novo acute myeloid leukemia: a randomized trial comparing mitoxantrone and intermediate-dose cytarabine with standard-dose cytarabine
    • PID: 11468148, COI: 1:CAS:528:DC%2BD3MXlsFKrtL4%3D
    • Stone RM, Berg DT, George SL, Dodge RK, Paciucci PA, Schulman PP, Lee EJ, Moore JO, Powell BL, Baer MR et al (2001) Postremission therapy in older patients with de novo acute myeloid leukemia: a randomized trial comparing mitoxantrone and intermediate-dose cytarabine with standard-dose cytarabine. Blood 98:548–553
    • (2001) Blood , vol.98 , pp. 548-553
    • Stone, R.M.1    Berg, D.T.2    George, S.L.3    Dodge, R.K.4    Paciucci, P.A.5    Schulman, P.P.6    Lee, E.J.7    Moore, J.O.8    Powell, B.L.9    Baer, M.R.10
  • 39
    • 84937556831 scopus 로고    scopus 로고
    • Treating acute myeloid leukemia in older adults
    • Wang ES (2014) Treating acute myeloid leukemia in older adults. Hematol Am Soc Hematol Educ Program 2014:14–20
    • (2014) Hematol Am Soc Hematol Educ Program , vol.2014 , pp. 14-20
    • Wang, E.S.1


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