Identification of pancreatic tumors in vivo with ligand-targeted, pH responsive mesoporous silica nanoparticles by multispectral optoacoustic tomography

Journal of Controlled Release

Volumn 231, Issue , 2016, Pages 60-67

  Gurka, Marie K ^a   Pender, Dillon ^a   Chuong, Phillip ^a   Fouts, Benjamin L ^a   Sobelov, Alexander ^a   McNally, Molly W ^a   Mezera, Megan ^a   Woo, Shiao Y ^a   McNally, Lacey R ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Mesoporous silica; Nanomedicine multispectral optoacoustic tomography; Pancreatic cancer; Theranostics

Indexed keywords

BINS; DISEASES; DRUG PRODUCTS; ENZYME INHIBITION; FLUORESCENCE; LIGANDS; MEDICAL NANOTECHNOLOGY; MESOPOROUS MATERIALS; NANOPARTICLES; PHOTOACOUSTIC EFFECT; SILICA; TOMOGRAPHY;

MESOPOROUS SILICA; MESOPOROUS SILICA NANOPARTICLES; MULTI-SPECTRAL; NANOPARTICLE BIODISTRIBUTION; OPTOACOUSTIC TOMOGRAPHY; PANCREATIC CANCERS; THERANOSTICS; UROKINASE PLASMINOGEN ACTIVATORS (UPA);

TUMORS;

CHITOSAN; GEMCITABINE; INDOCYANINE GREEN; LIGAND; MESOPOROUS SILICA NANOPARTICLE; UROKINASE; UROKINASE RECEPTOR; DEOXYCYTIDINE; NANOPARTICLE; SILICON DIOXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER DIAGNOSIS; CONTROLLED STUDY; DRUG RELEASE; EX VIVO STUDY; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MULTISPECTRAL OPTOACOUSTIC TOMOGRAPHY; NANOENCAPSULATION; NONHUMAN; PANCREAS CANCER; PH; PHOTOACOUSTIC TOMOGRAPHY; PRIORITY JOURNAL; TUMOR MICROENVIRONMENT; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; DIAGNOSTIC IMAGING; HUMAN; METABOLISM; NUDE RAT; PANCREAS TUMOR; PARTICLE SIZE; PHOTOACOUSTICS; POROSITY; PROCEDURES; SURFACE PROPERTY; THERANOSTIC NANOMEDICINE; TISSUE DISTRIBUTION; TOMOGRAPHY; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; CHITOSAN; DEOXYCYTIDINE; DRUG LIBERATION; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; INDOCYANINE GREEN; LIGANDS; MICE; NANOPARTICLES; PANCREATIC NEOPLASMS; PARTICLE SIZE; PHOTOACOUSTIC TECHNIQUES; POROSITY; RATS, NUDE; SILICON DIOXIDE; SURFACE PROPERTIES; THERANOSTIC NANOMEDICINE; TISSUE DISTRIBUTION; TOMOGRAPHY; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 84953455479     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2015.12.055     Document Type: Article

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