Peroxidated olive oil nanoemulsion for cancer targeted therapy

Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

Volumn 2015-November, Issue , 2015, Pages 2580-2583

  Dellacasa, Elena ^a   Pastorino, Laura ^a   Scanarotti, Chiara ^b   Vernazza, Stefania ^b   Bassi, Anna Maria ^b   Rolandi, Ranieri ^b   Ruggiero, Carmelina ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EMULSION; NANOMATERIAL; OLIVE OIL; REACTIVE OXYGEN METABOLITE;

CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; EMULSION; HUMAN; LIPID PEROXIDATION; METABOLISM; NEOPLASMS; THERAPEUTIC USE; TOXICITY;

CELL LINE; CELL SURVIVAL; EMULSIONS; HUMANS; LIPID PEROXIDATION; NANOSTRUCTURES; NEOPLASMS; OLIVE OIL; REACTIVE OXYGEN SPECIES;

EID: 84953265579     PISSN: 1557170X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1109/EMBC.2015.7318919     Document Type: Conference Paper

References (24)

1. P. T. Schumacker, "Reactive oxygen species in cancer cells: live by the sword, die by the sword," Cancer Cell, vol. 10, pp. 175-6, Sep 2006.
2. D. C. Wallace, "A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine," Annu Rev Genet, vol. 39, pp. 359-407, 2005.
3. T. P. Szatrowski and C. F. Nathan, "Production of large amounts of hydrogen peroxide by human tumor cells," Cancer Res, vol. 51, pp. 794-8, Feb 1 1991.
4. D. Trachootham, Y. Zhou, H. Zhang, Y. Demizu, Z. Chen, H. Pelicano, et al., "Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate," Cancer Cell, vol. 10, pp. 241-52, Sep 2006.
5. M. H. Yoo, X. M. Xu, B. A. Carlson, V. N. Gladyshev, and D. L. Hatfield, "Thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells," J Biol Chem, vol. 281, pp. 13005-8, May 12 2006.
6. M. Adachi, Y. Zhang, X. Zhao, T. Minami, R. Kawamura, Y. Hinoda, et al., "Synergistic effect of histone deacetylase inhibitors FK228 and m-carboxycinnamic acid bis-hydroxamide with proteasome inhibitors PSI and PS-341 against gastrointestinal adenocarcinoma cells," Clin Cancer Res, vol. 10, pp. 3853-62, Jun 1 2004.
7. A. Gupte and R. J. Mumper, "Elevated copper and oxidative stress in cancer cells as a target for cancer treatment," Cancer Treat Rev, vol. 35, pp. 32-46, Feb 2009.
8. S. Simizu, M. Takada, K. Umezawa, and M. Imoto, "Requirement of caspase-3(-like) protease-mediated hydrogen peroxide production for apoptosis induced by various anticancer drugs," J Biol Chem, vol. 273, pp. 26900-7, Oct 9 1998.
9. J. Alexandre, F. Batteux, C. Nicco, C. Chereau, A. Laurent, L. Guillevin, et al., "Accumulation of hydrogen peroxide is an early and crucial step for paclitaxel-induced cancer cell death both in vitro and in vivo," Int J Cancer, vol. 119, pp. 41-8, Jul 1 2006.
10. T. Yoshikawa, S. Kokura, K. Tainaka, Y. Naito, and M. Kondo, "A novel cancer therapy based on oxygen radicals," Cancer Res, vol. 55, pp. 1617-20, Apr 15 1995.
11. B. Rigas and Y. Sun, "Induction of oxidative stress as a mechanism of action of chemopreventive agents against cancer," Br J Cancer, vol. 98, pp. 1157-60, Apr 8 2008.
12. H. Pelicano, D. Carney, and P. Huang, "ROS stress in cancer cells and therapeutic implications," Drug Resist Updat, vol. 7, pp. 97-110, Apr 2004.
13. S. Pervaiz, "Pro-oxidant milieu blunts scissors: insight into tumor progression, drug resistance, and novel druggable targets," Curr Pharm Des, vol. 12, pp. 4469-77, 2006.
14. Q. Kong, J. A. Beel, and K. O. Lillehei, "A threshold concept for cancer therapy," Med Hypotheses, vol. 55, pp. 29-35, Jul 2000.
15. M. F. McCarty, J. Barroso-Aranda, and F. Contreras, "A twophase strategy for treatment of oxidant-dependent cancers," Med Hypotheses, vol. 69, pp. 489-96, 2007.
16. C. Nicco, A. Laurent, C. Chereau, B. Weill, and F. Batteux, "Differential modulation of normal and tumor cell proliferation by reactive oxygen species," Biomed Pharmacother, vol. 59, pp. 169-74, May 2005.
17. H. Ragelle, S. Crauste-Manciet, J. Seguin, D. Brossard, D. Scherman, P. Arnaud, et al., "Nanoemulsion formulation of fisetin improves bioavailability and antitumour activity in mice," International Journal of Pharmaceutics, vol. 427, pp. 452-459, 2012.
18. Martin Kello PUFAs enhance oxidative stress and apoptosis in tumor cells exposed to hypericin-mediated PDT, Photochem. Photobiol. Sci., 2010, 9, 1244-1251.
19. Girotti A. W. (1998) Lipid hydroperoxide generation, turnover, and effector action in biological systems, journal of lipid Research; 39: 1529-1542.
20. S. Ogawa, E. A. Decker, and D. J. McClements, "Production and Characterization of O/W Emulsions Containing Droplets Stabilized by Lecithin-Chitosan-Pectin Mutilayered Membranes", J. Agric. Food Chem., vol. 52, pp 3595-3600, 2004
21. T. Mossmann, "Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays", Journal of Immunological Methods, Vol. 65, pp. 55-63, December 1983.
22. E. Borenfreund and J. A. Puerner, "Toxicity determined in vitro by morphological alterations and neutral red absorption", Toxicology Letters, vol. 24, pp. 119-124, 1985.
23. R. J. Riddell, R. H. Clothier, and M. Balls, "An evaluation of three In vitro cytotoxicity assays", Food and Chemical Toxicology, Vol. 24, pp. 469-471, 1986.
24. H. Babich, and E. Borenfreund, "Structure-activity relationship (SAR) models established in vitro with the neutral red cytotoxicity assay", Toxicology in Vitro, Vol. 1, pp. 3-9, 1987.