"Frailty, thy name is woman" Syndrome of women with heart failure with preserved ejection fraction

Circulation: Cardiovascular Quality and Outcomes

Volumn 8, Issue , 2015, Pages S48-S51

  Pedrotty, Dawn M ^a   Jessup, Mariell ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Heart failure; Heart failure, diastolic; Women

Indexed keywords

CARDIOVASCULAR MALFORMATION; CARDIOVASCULAR RISK; COMORBIDITY; CORONARY ARTERY DISEASE; FEMALE; HEART FAILURE WITH PRESERVED EJECTION FRACTION; HEART FUNCTION; HEART MUSCLE CONTRACTILITY; HIGH RISK POPULATION; HUMAN; PATHOPHYSIOLOGY; PHENOTYPE; PRIORITY JOURNAL; REVIEW; AGE; AGED; FRAIL ELDERLY; HEALTH CARE DISPARITY; HEALTH DISPARITY; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART STROKE VOLUME; MALE; MIDDLE AGED; PROGNOSIS; RISK FACTOR; SEX DIFFERENCE;

AGE FACTORS; AGED; COMORBIDITY; FEMALE; FRAIL ELDERLY; HEALTH STATUS DISPARITIES; HEALTHCARE DISPARITIES; HEART FAILURE; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; PROGNOSIS; RISK FACTORS; SEX FACTORS; STROKE VOLUME; VENTRICULAR FUNCTION, LEFT;

EID: 84952718848     PISSN: 19417713     EISSN: 19417705     Source Type: Journal    
DOI: 10.1161/CIRCOUTCOMES.115.001700     Document Type: Review

References (42)

1. Roger VL, Go AS, Lloyd-Jones DM, Adams RJ, Berry JD, Brown TM, Carnethon MR, Dai S, de Simone G, Ford ES, Fox CS, Fullerton HJ, Gillespie C, Greenlund KJ, Hailpern SM, Heit JA, Ho PM, Howard VJ, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Makum DM, Marcus GM, Marelli A, Matchar DB, McDermott MM, Meigs JB, Moy CS, Mozaffarian D, Mussolino ME, Nichol G, Paynter NP, Rosamond WD, Sorlie PD, Stafford RS, Turan TN, Turner MB, Wong ND, Wylie-Rosett J; American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics: 2011 update-A report from the American Heart Association. Circulation. 2011;123:e18-e209.
2. Alagiakrishnan K, Banach M, Jones LG, Datta S, Ahmed A, Aronow WS. Update on diastolic heart failure or heart failure with preserved ejection fraction in the older adults. Ann Med. 2013;45:37-50. doi: 10.3109/07853890.2012.660493.
3. Borlaug BA, Redfield MM. Diastolic and systolic heart failure are distinct phenotypes within the heart failiure spectrum. Circulation. 2011;123:2006-2014.
4. Lee DS, Gona P, Vasan RS, Larson MG, Benjamin EJ, Wan TJ, Tu JV, Levy D. Relation of disease pathogenesis and risk factors to heart failure with preserved or reduced ejction fraction; insights from the framingham heart study of the national heart, lung, and blood institute. Circulation. 2009;119:3070-3077.
5. Masoudi FA, Havranek EP, Smith G, Fish RH, Steiner JF, Ordin DL, Krumholz HM. Gender, age, and heart failure with preserved left ventricular systolic function. J Am Coll Cardiol. 2003;41:217-223.
6. Ho JE, Lyass A, Lee DS, Vasan RS, Kannel WB, Larson MG, Levy D. Predictors of new-onset heart failure. Circ Heart Fail. 2013;6:279-286.
7. Agha G, Loucks EB, Tinker LF, Waring ME, Michaud DS, Foraker RE, Li W, Martin LW, Greenland P, Manson JE, Eaton CB. Healthy lifestyle and decreasing risk of heart failure in women: the Women's Health Initiative observational study. J Am Coll Cardiol. 2014;64:1777-1785. doi: 10.1016/j.jacc.2014.07.981.
8. Brouwers FP, Hillege HL, van Gilst WH, van Veldhuisen DJ. Comparing new onset heart failure with reduced ejection fraction and new onset heart failure with preserved ejection fraction: an epidemiologic perspective. Curr Heart Fail Rep. 2012;9:363-368. doi: 10.1007/s11897-012-0115-7.
9. Velagaleti RS, Gona P, Pencina MJ, Aragam J, Wang TJ, Levy D, D'Agostino RB, Lee DS, Kannel WB, Benjamin EJ, Vasan RS. Left ventricular hypertrophy patterns and incidence of heart failure with preserved versus reduced ejection fraction. Am J Cardiol. 2014;113:117-122. doi: 10.1016/j.amjcard.2013.09.028.
10. Paulus WJ, Tschope C, Sanderson TC, Rusconi C, Flachskamp FA, Rademakers FE, Marino P, Smiseth OA, De KG, Leite-Moreira AF, Borbel A, Edes I, Handoko ML, Heymans S, Pezzali N, Dickstein K, Fraswer AG, Brutsaert DL. How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the heart failure and echocardiography associations of the european society of cardiology. Eur Heart J. 2007;28:2539-2550.
11. Vasan RS, Levy D. Defining diastolic heart failure: a call for standardized diagnostic criteria. Circulation. 2000;101:2118-2121.
12. McMurragy JJ, Adamopoulos S, Anker SD, Auricchio A, Bohm M, Dickestein K, Falk V, Flippatos G, Fonseca C, Gomez-Sanchez MA, Jaarsma T, Køber L, Lip GY, Maggioni AP, Parkhomenko A, Pieske BM, Popescu BA, Rønnevik PK, Rutten FH, Schwitter J, Seferovic P, Stepinska J, Trindade PT, Voors AA, Zannad F, Zeiher A; Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology, Bax JJ, Baumgartner H, Ceconi C, Dean V, Deaton C, Fagard R, Funck-Brentano C, Hasdai D, Hoes A, Kirchhof P, Knuuti J, Kolh P, McDonagh T, Moulin C, Popescu BA, Reiner Z, Sechtem U, Sirnes PA, Tendera M, Torbicki A, Vahanian A, Windecker S, McDonagh T, Sechtem U, Bonet LA, Avraamides P, Ben Lamin HA, Brignole M, Coca A, Cowburn P, Dargie H, Elliott P, Flachskampf FA, Guida GF, Hardman S, Iung B, Merkely B, Mueller C, Nanas JN, Nielsen OW, Orn S, Parissis JT, Ponikowski P; ESC Committee for Practice Guidelines. ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: the task force for the diagnosis and treatment of acute and chronic heart failure 2012 of the european society of cardiology. Developed in collaboration with the heart failure association (HFA) of the ESC. Eur Heart J. 2012;33:1787-1847.
13. Senni M, Paulus WJ, Gavazzi A, Fraser AG, Diez J, Solomon SD, Smiseth OA, Guazzi M, Lam CS, Maggioni AP, Tschope C, Metra M, Hummel SL, Edelmann F, Ambrosio G, Coats AJ, Filippatos GS, Gheorghiade M, Anker SD, Levy D, Pfeffer MA, Stough WG, Pieske BM. New strategies for heart failure with preserved ejection fraction: the importance of targeted therapies for heart failure phenotypes. Eur Heart J. 2014;35:2797-2811.
14. Desai AS, Lewis EF, Li R, Solomon SD, Assmann SF, Boineau R, Clausell N, Diaz R, Fleg JL, Gordeev I, McKinlay S, O'Meara E, Shaburishvili T, Pitt B, Pfeffer MA. Rationale and design of the treatment of preserved cardiac function heart failure with an aldosterone antagonist trial: a randomized, controlled study of spironolactone in patients with symptomatic heart failure and preserved ejection fraction. Am Heart J. 2011;162:966-972.
15. McMurray JJ, Ostergren J, Swedberg K, Granger CB, Held P, Michelson EL, Olofsson B, Yusuf S, Pfeffer MA; CHARM Investigators and Committees. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensinconverting-enzyme inhibitors: the CHARM-Added trial. Lancet. 2003;362:777-781.
16. Massie BM, Carson PE, McMurray JJ, Komajda M, McKelvie R, Zile MR, Anderson S, Donovan M, Iverson E, Staiger C, Ptaszynska A; I-PRESERVE Investigators. Irbesartan in patients with heart failure and preserved ejection fraction. N Engl J Med. 2008;359:2456-2467. doi: 10.1056/NEJMoa0805450.
17. Wang AY, Wang M, Lam CW, Chan IH, Lui SF. Heart failure with preserved or reduced ejection fraction in patients treated with peritoneal dialysis. Am J Kidney Dis. 2013;61:975-983.
18. Caughey MC, Avery CL, Ni H, Solomon SD, Matsushita K, Wruck LM, Rosamond WD, Loehr LR. Outcomes of patients with anemia and acute decompensated heart failure with preserved versus reduced ejection fraction (from the ARIC study community surveillance). Am J Cardiol. 2014;114:1850-1854. doi: 10.1016/j.amjcard.2014.09.024.
19. Yancy CW, Lopatin M, Stevenson LW, De Marco T, Fonarow GC; ADHERE Scientific Advisory Committee and Investigators. Clinical presentation, management, and in-hospital outcomes of patients admitted with acute decompensated heart failure with preserved systolic function: a report from the Acute Decompensated Heart Failure National Registry (ADHERE) Database. J Am Coll Cardiol. 2006;47:76-84. doi: 10.1016/j.jacc.2005.09.022.
20. Shah SJ, Katz DH, Selvaraj S, Burke MA, Yancy CW, Gheorghiade M, Bonow RO, Huang CC, Deo RC. Phenomapping for novel classification of heart failure with preserved ejection fraction. Circulation. 2015;131:269-279. doi: 10.1161/CIRCULATIONAHA.114.010637.
21. Rossignol P, Zannad F. Regional differences in heart failure with preserved ejection fraction trials: when nephrology meets cardiology but East does not meet West. Circulation. 2015;131:7-10. doi: 10.1161/CIRCULATIONAHA.114.013637.
22. Kristensen SL, Køber L, Jhund PS, Solomon SD, Kjekshus J, McKelvie RS, Zile MR, Granger CB, Wikstrand J, Komajda M, Carson PE, Pfeffer MA, Swedberg K, Wedel H, Yusuf S, McMurray JJ. International geographic variation in event rates in trials of heart failure with preserved and reduced ejection fraction. Circulation. 2015;131:43-53. doi: 10.1161/CIRCULATIONAHA.114.012284.
23. Damman K, Perez AC, Anand IS, Komajda M, McKelvie RS, Zile MR, Massie B, Carson PE, McMurray JJ. Worsening renal function and outcome in heart failure patients with preserved ejection fraction and the impact of angiotensin receptor blocker treatment. J Am Coll Cardiol. 2014;64:1106-1113. doi: 10.1016/j.jacc.2014.01.087.
24. Mohammed SF, Hussain I, Abou Ezzeddine OF, Takahama H, Kwon SH, Forfia P, Roger VL, Redfield MM. Right ventricular function in heart failure with preserved ejection fraction: a community-based study. Circulation. 2014;130:2310-2320. doi: 10.1161/CIRCULATIONAHA.113.008461.
25. Lindman BR, Dávila-Román VG, Mann DL, McNulty S, Semigran MJ, Lewis GD, de las Fuentes L, Joseph SM, Vader J, Hernandez AF, Redfield MM. Cardiovascular phenotype in HFpEF patients with or without diabetes: a RELAX trial ancillary study. J Am Coll Cardiol. 2014;64:541-549. doi: 10.1016/j.jacc.2014.05.030.
26. Chung AK, Das SR, Leonard D, Peshock RM, Kazi F, Abdullah SM, Canham RM, Levine BD, Drazner MH. Women have higher left ventricular ejection fractions than men indepenedent of differences in left ventricular volume: the dallas heart study. Circulation. 2006;113:1597-1604.
27. de Simone F, Devereux RB, Daniels SR, Meyer RA. Gender differences in left ventricular growth. Hypertension. 1995;26:979-983.
28. Aurigemma GP, Silver KH, McLaughlin M, Mauser J, Gaasch WH. Impact of chamber geometry and gender on lfet ventricular systolic function in patients 60 years of age with aortic stenosis. Am J Cardiol. 1994;74:794-798.
29. Petrov G, Regitz-Zagrosek V, Lehmkuhl E, Krabatsch T, Dunkel A, Dandel M, Dworatzek E, Mahmoodzadeh S, Schubert C, Becher E, Hampl H, Hetzer R. Regression of myocardial hypertrophy after aortic valve replacement: faster in women? Circulation. 2010;122:S23-S28.
30. Fleg JL, O'Connor F, Gerstenblith G, Becker LC, Clulow J, Schulman SP, Lakatta EG. Impace of age on the cardiovascular response to dynamic upright exercise in healthy men and women. J Appl Phys. 1995;78:890-900.
31. Rossi P, Frances Y, Kingwell BA, Ahimastos AA. Gender differences in artery wall biomechanical properties throughout life. J Hypertens. 2011;29:1023-1033. doi: 10.1097/HJH.0b013e328344da5e.
32. Grandi A, Venco A, Barzizza F, Scalise F, Pantaleo P, Finardi G. Influence of age and sex on left ventricular anatomy and function in normals. Cardiology. 1992;81:8-13.
33. Föll D, Jung B, Schilli E, Staehle F, Geibel A, Hennig J, Bode C, Markl M. Magnetic resonance tissue phase mapping of mocardial motion: new insight in age and gender. Circ Cardiovasc Imaging. 2010;3:588-595.
34. Scantlebury DC, Borlaug BA. Why are women more likely than men to develop heart failure with preserved ejection fraction? Curr Opin Cardiol. 2011;26:562-568. doi: 10.1097/HCO.0b013e32834b7faf.
35. Lund LH, Donal E, Oger E, Hage C, Persson H, Haugen-Löfman I, Ennezat PV, Sportouch-Dukhan C, Drouet E, Daubert JC, Linde C; KaRen Investigators. Association between cardiovascular vs non-cardiovascular co-morbidities and outcomes in heart failure with preserved ejection fraction. Eur J Heart Fail. 2014;16:992-1001. doi: 10.1002/ejhf.137.
36. Oluleye OW, Rector TS, Win S, McMurray JJ, Zile MR, Komajda M, McKelvie RS, Massie B, Carson PE, Anand IS. History of atrial fibrillation as a risk factor in patients with heart failure and preserved ejection fraction. Circ Heart Fail. 2014;7:960-966. doi: 10.1161/CIRCHEARTFAILURE.114.001523.
37. Renoux C, Patenaude V, Suissa S. Incidence, mortality, and sex differences of non-valvular atrial fibrillation: a population-based study. J Am Heart Assoc. 2014;3:e001402. doi: 10.1161/JAHA.114.001402.
38. Rossi A, Gheorghiade M, Triposkiadis F, Solomon SD, Pieske B, Butler J. Left atrium in heart failure with preserved ejection fraction: structure, function, and significance. Circ Heart Fail. 2014;7:1042-1049. doi: 10.1161/CIRCHEARTFAILURE.114.001276.
39. Kumar P, Patel A, Mounsey JP, Chung EH, Schwartz JD, Pursell IW, Gehi AK. Effect of left ventricular diastolic dysfunction on outcomes of atrial fibrillation ablation. Am J Cardiol. 2014;114:407-411. doi: 10.1016/j.amjcard.2014.05.012.
40. Yamamoto K, Origasa H, Suzuki Y, Takahashi T, Shinozaki T, Watanabe T, Sakata Y, Izumi C, Taira K, Hori M; J-DHF Investigators. Relation of risk factors with response to carvedilol in heart failure with preserved ejection fraction-A report from the Japanese Diastolic Heart Failure Study (J-DHF). J Cardiol. 2014;63:424-431. doi: 10.1016/j. jjcc.2013.10.014.
41. Paulus WJ, Tschope C. A novel paradigm for heart failure with preserved ejection fraction. Am J Coll Cardiol. 2013;62:263-271.
42. Mohammed SF, Hussain S, Mirzoyev SA, Edwards WD, Maleszewski JJ, Redfield MM. Coronary microvascular rarefaction and myocardial fibrosis in heart failure with preserved ejction fraction (epub ahead of print). Circulation. 2014.