Scopariusicides, Novel Unsymmetrical Cyclobutanes: Structural Elucidation and Concise Synthesis by a Combination of Intermolecular [2 + 2] Cycloaddition and C-H Functionalization

Organic Letters

Volumn 17, Issue 24, 2015, Pages 6062-6065

  Zhou, Min ^a,b   Li, Xing Ren ^a,c   Tang, Jian Wei ^a,c   Liu, Yang ^d   Li, Xiao Nian ^a   Wu, Bin ^a   Qin, Hong Bo ^a   Du, Xue ^a   Li, Li Mei ^d   Wang, Wei Guang ^a   Pu, Jian Xin ^a   Sun, Han Dong ^a  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b YUNNAN MINZU UNIVERSITY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d CHENGDU MEDICAL COLLEGE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOBUTANE DERIVATIVE; IMMUNOSUPPRESSIVE AGENT; SCOPARIUSICIDE A; SCOPARIUSICIDE B;

CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; CYCLOADDITION; DRUG DEVELOPMENT; DRUG EFFECTS; HUMAN; ISODON; STEREOISOMERISM; SYNTHESIS; T LYMPHOCYTE; X RAY CRYSTALLOGRAPHY;

CATALYSIS; CRYSTALLOGRAPHY, X-RAY; CYCLOADDITION REACTION; CYCLOBUTANES; DRUG DISCOVERY; HUMANS; IMMUNOSUPPRESSIVE AGENTS; ISODON; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; STEREOISOMERISM; T-LYMPHOCYTES;

EID: 84952657024     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/acs.orglett.5b03079     Document Type: Article

References (20)

1. Morrison, H.; Rodriguez, O. J. Photochem. 1974, 3, 471 10.1016/0047-2670(74)80048-1
2. Schuster, D. I.; Lem, G.; Kaprinidis, N. A. Chem. Rev. 1993, 93, 3 10.1021/cr00017a001
3. Hoffmann, N. Chem. Rev. 2008, 108, 1052 10.1021/cr0680336
4. Ichikawa, M.; Takahashi, M.; Aoyagi, S.; Kibayashi, C. J. Am. Chem. Soc. 2004, 126, 16553 10.1021/ja0401702
5. Mangion, I. K.; MacMillan, D. W. C. J. Am. Chem. Soc. 2005, 127, 3696 10.1021/ja050064f
6. Lee-Ruff, E.; Mladenova, G. Chem. Rev. 2003, 103, 1449 10.1021/cr010013a
7. Gutekunst, W. R.; Baran, P. S. J. Org. Chem. 2014, 79, 2430 10.1021/jo4027148
8. Ischay, M. A.; Anzovino, M. E.; Du, J.; Yoon, T. P. J. Am. Chem. Soc. 2008, 130, 12886 10.1021/ja805387f
9. Du, J.; Yoon, T. P. J. Am. Chem. Soc. 2009, 131, 14604 10.1021/ja903732v
10. Baik, T. G.; Luis, A. L.; Wang, L. C.; Krische, M. J. J. Am. Chem. Soc. 2001, 123, 6716 10.1021/ja010800p
11. Gutekunst, W. R.; Baran, P. S. J. Am. Chem. Soc. 2011, 133, 19076 10.1021/ja209205x
12. Gutekunst, W. R.; Gianatassio, R.; Baran, P. S. Angew. Chem., Int. Ed. 2012, 51, 7507 10.1002/anie.201203897
13. Frébault, F.; Maulide, N. Angew. Chem., Int. Ed. 2012, 51, 2815 10.1002/anie.201108592
14. Zaitsev, V. G.; Shabashov, D.; Daugulis, O. J. Am. Chem. Soc. 2005, 127, 13154 10.1021/ja054549f
15. Shabashov, D.; Daugulis, O. J. Am. Chem. Soc. 2010, 132, 3965 10.1021/ja910900p
16. Zhou, M.; Geng, H. C.; Zhang, H. B.; Dong, K.; Wang, W. G.; Du, X.; Li, X. N.; He, F.; Qin, H. B.; Li, Y.; Pu, J. X.; Sun, H. D. Org. Lett. 2013, 15, 314 10.1021/ol303226c
17. Zhou, M.; Zhang, H. B.; Wang, W. G.; Gong, N. B.; Zhan, R.; Li, X. N.; Du, X.; Li, L. M.; Li, Y.; Lu, Y.; Pu, J. X.; Sun, H. D. Org. Lett. 2013, 15, 4446 10.1021/ol401991u
18. Liu, Y.; Yang, T.; Li, H.; Li, M. H.; Liu, J.; Wang, Y. T.; Yang, S. X.; Zheng, J.; Luo, X. Y.; Lai, Y.; Yang, P.; Li, L. M.; Zou, Q. Br. J. Pharmacol. 2013, 168, 632 10.1111/j.1476-5381.2012.02172.x
19. Ting, C. P.; Maimone, T. J. Angew. Chem., Int. Ed. 2014, 53, 3115 10.1002/anie.201311112
20. Feng, Y. Q.; Chen, G. Angew. Chem., Int. Ed. 2010, 49, 958 10.1002/anie.200905134